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The map label for this gene is lplA-like1 [H]

Identifier: 15897928

GI number: 15897928

Start: 919106

End: 919945

Strand: Reverse

Name: lplA-like1 [H]

Synonym: SSO1060

Alternate gene names: 15897928

Gene position: 919945-919106 (Counterclockwise)

Preceding gene: 15897929

Following gene: 15897927

Centisome position: 30.74

GC content: 36.67

Gene sequence:

>840_bases
ATGAGTTGGAGATTTGTCTCTCTCCCTCCTCAAGATGGCTATCACATGGTAACTTCATTTGTATCGGTAGCGGATTATGT
AAATAGAGGAGGAAAAAATACATTATTGGTTTTTTCAGTTAAAGAGCCTTTTGTAAATGTGGGAATCCACCAAGAAGTAT
GGCTAGAAGTTGATTTAGAATTTACTAAAAAGATGAAAATCCCAGTCGTTAGGCGTGATTTAGGAGGAGGCACAGTAGTA
ATAACACCAGGTGAGCATGATTATTTTATTGTTGTTAGACAAGAGGACGCACCAAGAAATCCAAGTGAATTATATAAGAA
ATTCCTCACACCCATAGTAAACGTTTTACGTTCATATGGGTTAAAAGCCGATTTAAGAGATCAAGATATAGTAGTAAATG
GAAAGAAAATAAGTGGAAATGGCGCGATGACACACGGTAATTCAATCGTAATAGCCGGCAACATTTTGTTGAGTCTAGAT
ATTGACCTAATTAGTAAATGTATAAGGGTTCCAACAGAAAAGTTTAGGGATAAAATGGCTAAGGATATGTCAGAGTGGTT
AACATCATTAGAGAGAGAATTAGGATATATTCCGCCTAAGGAGGAGATTAACAAGAAACTTAAGGAGGCTTTTGAAAAGG
AATTAGGTATAAAATTTGAGGATTCGACGTTAACGCCAGAAGAAATAGAATTATGGGAGAAATTGGCAAGCGAAAAAGCT
AAAGAGGAATGGATATTTTACAAAGATAATAGGCATCGTGATATTCACACGGAGAGATGCGTTAAAATTTCGTCTGCGGC
ACTCTTTGCCACCTTGACTATAAGGCTAGGAAGTTGCTAA

Upstream 100 bases:

>100_bases
AATCCAGAGGAGTTAAAACAACTATTTAGTGGCCAAGCAGCTATACAGAAATTGAAGGAATTAATAGCCTCTGAAAAATT
AACATGCAAGAGGCTATAAA

Downstream 100 bases:

>100_bases
GAATTACCCTTAAAATAGCAAATAAGAAAATTGATGAAATATCAATTTCTGGTGACTTCTTCATTATGTCACCAAATGGG
TTCATAGAATATTTGGAAGA

Product: lipoate protein ligase A

Products: NA

Alternate protein names: Lipoate--protein ligase subunit 1 [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSWRFVSLPPQDGYHMVTSFVSVADYVNRGGKNTLLVFSVKEPFVNVGIHQEVWLEVDLEFTKKMKIPVVRRDLGGGTVV
ITPGEHDYFIVVRQEDAPRNPSELYKKFLTPIVNVLRSYGLKADLRDQDIVVNGKKISGNGAMTHGNSIVIAGNILLSLD
IDLISKCIRVPTEKFRDKMAKDMSEWLTSLERELGYIPPKEEINKKLKEAFEKELGIKFEDSTLTPEEIELWEKLASEKA
KEEWIFYKDNRHRDIHTERCVKISSAALFATLTIRLGSC

Sequences:

>Translated_279_residues
MSWRFVSLPPQDGYHMVTSFVSVADYVNRGGKNTLLVFSVKEPFVNVGIHQEVWLEVDLEFTKKMKIPVVRRDLGGGTVV
ITPGEHDYFIVVRQEDAPRNPSELYKKFLTPIVNVLRSYGLKADLRDQDIVVNGKKISGNGAMTHGNSIVIAGNILLSLD
IDLISKCIRVPTEKFRDKMAKDMSEWLTSLERELGYIPPKEEINKKLKEAFEKELGIKFEDSTLTPEEIELWEKLASEKA
KEEWIFYKDNRHRDIHTERCVKISSAALFATLTIRLGSC
>Mature_278_residues
SWRFVSLPPQDGYHMVTSFVSVADYVNRGGKNTLLVFSVKEPFVNVGIHQEVWLEVDLEFTKKMKIPVVRRDLGGGTVVI
TPGEHDYFIVVRQEDAPRNPSELYKKFLTPIVNVLRSYGLKADLRDQDIVVNGKKISGNGAMTHGNSIVIAGNILLSLDI
DLISKCIRVPTEKFRDKMAKDMSEWLTSLERELGYIPPKEEINKKLKEAFEKELGIKFEDSTLTPEEIELWEKLASEKAK
EEWIFYKDNRHRDIHTERCVKISSAALFATLTIRLGSC

Specific function: Lipoate-protein ligase catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. This subunit can alone only catalyze the lipoat

COG id: COG0095

COG function: function code H; Lipoate-protein ligase A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lplA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.7.7.63 [H]

Molecular weight: Translated: 31830; Mature: 31699

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWRFVSLPPQDGYHMVTSFVSVADYVNRGGKNTLLVFSVKEPFVNVGIHQEVWLEVDLE
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEECCCCEEEEEEEEEE
FTKKMKIPVVRRDLGGGTVVITPGEHDYFIVVRQEDAPRNPSELYKKFLTPIVNVLRSYG
ECCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
LKADLRDQDIVVNGKKISGNGAMTHGNSIVIAGNILLSLDIDLISKCIRVPTEKFRDKMA
CCCCCCCCCEEEECEEECCCCCEECCCEEEEECCEEEEECHHHHHHHHHCCHHHHHHHHH
KDMSEWLTSLERELGYIPPKEEINKKLKEAFEKELGIKFEDSTLTPEEIELWEKLASEKA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHH
KEEWIFYKDNRHRDIHTERCVKISSAALFATLTIRLGSC
HHCEEEEECCCCCCCCHHHHHHHHHHHEEEEEEEEECCC
>Mature Secondary Structure 
SWRFVSLPPQDGYHMVTSFVSVADYVNRGGKNTLLVFSVKEPFVNVGIHQEVWLEVDLE
CCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEECCCCEEEEEEEEEE
FTKKMKIPVVRRDLGGGTVVITPGEHDYFIVVRQEDAPRNPSELYKKFLTPIVNVLRSYG
ECCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
LKADLRDQDIVVNGKKISGNGAMTHGNSIVIAGNILLSLDIDLISKCIRVPTEKFRDKMA
CCCCCCCCCEEEECEEECCCCCEECCCEEEEECCEEEEECHHHHHHHHHCCHHHHHHHHH
KDMSEWLTSLERELGYIPPKEEINKKLKEAFEKELGIKFEDSTLTPEEIELWEKLASEKA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHH
KEEWIFYKDNRHRDIHTERCVKISSAALFATLTIRLGSC
HHCEEEEECCCCCCCCHHHHHHHHHHHEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]