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The map label for this gene is rnz [H]

Identifier: 15897910

GI number: 15897910

Start: 902135

End: 903010

Strand: Reverse

Name: rnz [H]

Synonym: SSO1043

Alternate gene names: 15897910

Gene position: 903010-902135 (Counterclockwise)

Preceding gene: 15897911

Following gene: 15897907

Centisome position: 30.18

GC content: 34.47

Gene sequence:

>876_bases
GTGATTCAAATATTCTTTTTAGGTACGGGAGCAGGTTCCCCTTCTAAGAAGAGAAAATTACCAGCATTCTTGGTAAGGAG
AGAGGGAGTAAACATTTTATTAGACTGTGGAGAAGGAACACAATATACGTTAATGAACTATAAGTTAGGAATAAATTCAA
TAAAAATCATAGGAATATCTCACATGCATGGAGATCACGTATTTGGACTACTAGGAGTGATTGCAAGCATGGGTCTTCTA
GATAGAAAGGAGACATTATATATACTAGGCCCAAGAAAACTTAAGGATTTCCTATACACATCCTTCGAATACTCCAAATT
CAATCCTTCATTCAAGATAGAGTTCATAGATAACTATAATGACGAGAATATTACAATTTCTACATTTAAAACTTGCCATA
CCATAGAGTCCCAAGGATATTTAATCATGGAAAAGGATAGAGTAAAAATAGATGAAGAAAAATTAGAAAAAGAAAAAATA
AGAGATTGGAGAGTAATAAGAAAATTAAAAGAAGGAAAGACAGTGGAGTATAATGGCAAGTTATTAAAGCCTGAGGACTA
TTTAGTGATAAAGAGAGGATCGAAAGTAGCCTATACTGGAGATACTATGCCTTGTCAATCTGTAGTAGACTCTGTTAAAG
GTGTCGATATCTTAATTCACGATTCAACATTCTTAGATGAACCCTCAGCTTATACGTACGGACATTCAAACGTAACAGAT
GCTGCAAAAATCGCTTTGGAAGCATCAGTTAAACTGTTAGCATTAACACACATAAGTCCCAGATATGAGGACGTAAGTGA
GCATTTAAAAATGGCTAGGAGAATTTTCCCGAAATCCATTTTACCAGACGACCTATCTTACATAACTATTAAGTAG

Upstream 100 bases:

>100_bases
TTATAGATAAATTAAAGGAAAATAGTTTTATTATAAAAGGTCTACATTACTTATACTCACATAAGAGTTTAACAAGGGCA
ATTTACGTGGTGCAGAAAAA

Downstream 100 bases:

>100_bases
TTAGACATCTGGAGGAACGGGGTTATCCCAAAGAGGTACTCCATGAGCCGTTTTTGGAGCTAACCAATCGACTATCTCTT
TAGGATTTTGGTATTCTATA

Product: hypothetical protein

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIQIFFLGTGAGSPSKKRKLPAFLVRREGVNILLDCGEGTQYTLMNYKLGINSIKIIGISHMHGDHVFGLLGVIASMGLL
DRKETLYILGPRKLKDFLYTSFEYSKFNPSFKIEFIDNYNDENITISTFKTCHTIESQGYLIMEKDRVKIDEEKLEKEKI
RDWRVIRKLKEGKTVEYNGKLLKPEDYLVIKRGSKVAYTGDTMPCQSVVDSVKGVDILIHDSTFLDEPSAYTYGHSNVTD
AAKIALEASVKLLALTHISPRYEDVSEHLKMARRIFPKSILPDDLSYITIK

Sequences:

>Translated_291_residues
MIQIFFLGTGAGSPSKKRKLPAFLVRREGVNILLDCGEGTQYTLMNYKLGINSIKIIGISHMHGDHVFGLLGVIASMGLL
DRKETLYILGPRKLKDFLYTSFEYSKFNPSFKIEFIDNYNDENITISTFKTCHTIESQGYLIMEKDRVKIDEEKLEKEKI
RDWRVIRKLKEGKTVEYNGKLLKPEDYLVIKRGSKVAYTGDTMPCQSVVDSVKGVDILIHDSTFLDEPSAYTYGHSNVTD
AAKIALEASVKLLALTHISPRYEDVSEHLKMARRIFPKSILPDDLSYITIK
>Mature_291_residues
MIQIFFLGTGAGSPSKKRKLPAFLVRREGVNILLDCGEGTQYTLMNYKLGINSIKIIGISHMHGDHVFGLLGVIASMGLL
DRKETLYILGPRKLKDFLYTSFEYSKFNPSFKIEFIDNYNDENITISTFKTCHTIESQGYLIMEKDRVKIDEEKLEKEKI
RDWRVIRKLKEGKTVEYNGKLLKPEDYLVIKRGSKVAYTGDTMPCQSVVDSVKGVDILIHDSTFLDEPSAYTYGHSNVTD
AAKIALEASVKLLALTHISPRYEDVSEHLKMARRIFPKSILPDDLSYITIK

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=326, Percent_Identity=31.5950920245399, Blast_Score=124, Evalue=7e-29,
Organism=Escherichia coli, GI87082078, Length=306, Percent_Identity=32.3529411764706, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322932, Length=312, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 33098; Mature: 33098

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIFFLGTGAGSPSKKRKLPAFLVRREGVNILLDCGEGTQYTLMNYKLGINSIKIIGIS
CEEEEEEECCCCCCHHHHCCCCEEEEECCCEEEEECCCCCEEEEEEEEECCCEEEEEEEE
HMHGDHVFGLLGVIASMGLLDRKETLYILGPRKLKDFLYTSFEYSKFNPSFKIEFIDNYN
CCCCCHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHCCEEECCCCCCEEEEEECCCC
DENITISTFKTCHTIESQGYLIMEKDRVKIDEEKLEKEKIRDWRVIRKLKEGKTVEYNGK
CCEEEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCE
LLKPEDYLVIKRGSKVAYTGDTMPCQSVVDSVKGVDILIHDSTFLDEPSAYTYGHSNVTD
EECCCCEEEEECCCEEEEECCCCCHHHHHHHCCCEEEEEECCCCCCCCCCEECCCCCCCH
AAKIALEASVKLLALTHISPRYEDVSEHLKMARRIFPKSILPDDLSYITIK
HHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MIQIFFLGTGAGSPSKKRKLPAFLVRREGVNILLDCGEGTQYTLMNYKLGINSIKIIGIS
CEEEEEEECCCCCCHHHHCCCCEEEEECCCEEEEECCCCCEEEEEEEEECCCEEEEEEEE
HMHGDHVFGLLGVIASMGLLDRKETLYILGPRKLKDFLYTSFEYSKFNPSFKIEFIDNYN
CCCCCHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHCCEEECCCCCCEEEEEECCCC
DENITISTFKTCHTIESQGYLIMEKDRVKIDEEKLEKEKIRDWRVIRKLKEGKTVEYNGK
CCEEEEEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCE
LLKPEDYLVIKRGSKVAYTGDTMPCQSVVDSVKGVDILIHDSTFLDEPSAYTYGHSNVTD
EECCCCEEEEECCCEEEEECCCCCHHHHHHHCCCEEEEEECCCCCCCCCCEECCCCCCCH
AAKIALEASVKLLALTHISPRYEDVSEHLKMARRIFPKSILPDDLSYITIK
HHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA