BacMap

Definition	Sulfolobus solfataricus P2 chromosome, complete genome.
Accession	NC_002754
Length	2,992,245

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The map label for this gene is cysA [H]

Identifier: 15897902

GI number: 15897902

Start: 895429

End: 896043

Strand: Reverse

Name: cysA [H]

Synonym: SSO1034

Alternate gene names: 15897902

Gene position: 896043-895429 (Counterclockwise)

Preceding gene: 15897903

Following gene: 15897894

Centisome position: 29.95

GC content: 30.41

Gene sequence:

>615_bases
TTGAGTGAGATAGTTAAAGTAGATGTTTTTAAGAAATTTAAAAATTTTGAGCTAAAAGTAAATTTCAGTGTAAATGAAGG
AGAGAAAGTTTTAATTCAAGGTCCAAATGGTTCTGGTAAGACTACTTTACTATATCTAATTTATGGCGTGTTAAATCCAG
ATTCTGGATACGTAAGGGTATTTAATAAGAATCCAACTGTAGAGCTAAGAAAAAGTGAAATGTACATGCTAGAGGAGTAT
TTAATATTTCTAGAAAATGCTAGTTTAAAGGAAAACTTAGAGTTCATAACGTCATTAAGGGATTTTAATATAAATAAAAC
AGAGGAGCTAATTAATAAATTCGATCTACCTCTTTATAAGAAATCTTACCAACTAAGTTCTGGTCAGAGAAGGTTATTTA
AATTAGCTTTAGCCTTCTCTGCCGAGGCCAAATTACTACTACTTGACGAGCCTACATCTAATTTAGATATAGAAAATTCT
AAAGCGGTCAAGGATATGATAAGGGAGTATAGCGGTACAATAATTTTTGCTTCTCATGATCTTCTGCTCAAAGAATCATG
TGATAAGACAATATATTTAAGAACAGGAAAAATAGAGCGAATTGAGATTAAATAA

Upstream 100 bases:

>100_bases
GCTGGACTAATTGGATTATTAGTATCTTCTATTTTGATTGAGTACTATACGGTGTTTTCTGCTTACAGTAATCAGCACAA
ATTCCTAAAGGTGAGGAGTA

Downstream 100 bases:

>100_bases
TTTATAAAGTGCAGTTTTTATTATTTATTTTTCCTTTAATAAAAATACGCGAATTTGGTATATTTATTACATTATAGTAT
ATATAATCGCCTTAATTTAA

Product: ABC transporter, ATP binding protein

Products: NA

Alternate protein names: Sulfate-transporting ATPase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSEIVKVDVFKKFKNFELKVNFSVNEGEKVLIQGPNGSGKTTLLYLIYGVLNPDSGYVRVFNKNPTVELRKSEMYMLEEY
LIFLENASLKENLEFITSLRDFNINKTEELINKFDLPLYKKSYQLSSGQRRLFKLALAFSAEAKLLLLDEPTSNLDIENS
KAVKDMIREYSGTIIFASHDLLLKESCDKTIYLRTGKIERIEIK

Sequences:

>Translated_204_residues
MSEIVKVDVFKKFKNFELKVNFSVNEGEKVLIQGPNGSGKTTLLYLIYGVLNPDSGYVRVFNKNPTVELRKSEMYMLEEY
LIFLENASLKENLEFITSLRDFNINKTEELINKFDLPLYKKSYQLSSGQRRLFKLALAFSAEAKLLLLDEPTSNLDIENS
KAVKDMIREYSGTIIFASHDLLLKESCDKTIYLRTGKIERIEIK
>Mature_203_residues
SEIVKVDVFKKFKNFELKVNFSVNEGEKVLIQGPNGSGKTTLLYLIYGVLNPDSGYVRVFNKNPTVELRKSEMYMLEEYL
IFLENASLKENLEFITSLRDFNINKTEELINKFDLPLYKKSYQLSSGQRRLFKLALAFSAEAKLLLLDEPTSNLDIENSK
AVKDMIREYSGTIIFASHDLLLKESCDKTIYLRTGKIERIEIK

Specific function: Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system [H]

COG id: COG1136

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=171, Percent_Identity=29.2397660818713, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI31657092, Length=201, Percent_Identity=27.8606965174129, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI45446740, Length=184, Percent_Identity=26.6304347826087, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI47078218, Length=184, Percent_Identity=26.6304347826087, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI105990541, Length=173, Percent_Identity=28.3236994219653, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI21536376, Length=175, Percent_Identity=26.8571428571429, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI27436953, Length=178, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI73747915, Length=198, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI255708477, Length=195, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI42741659, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI148612844, Length=199, Percent_Identity=27.6381909547739, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI27262624, Length=184, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI27262626, Length=184, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI153792144, Length=196, Percent_Identity=26.0204081632653, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI27477115, Length=200, Percent_Identity=25.5, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1786703, Length=197, Percent_Identity=28.4263959390863, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081834, Length=197, Percent_Identity=30.9644670050761, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87081709, Length=174, Percent_Identity=28.735632183908, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1789891, Length=206, Percent_Identity=27.6699029126214, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790467, Length=200, Percent_Identity=30, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1790534, Length=183, Percent_Identity=28.4153005464481, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788225, Length=222, Percent_Identity=27.4774774774775, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI2367384, Length=190, Percent_Identity=31.0526315789474, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789593, Length=218, Percent_Identity=25.6880733944954, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=24.4131455399061, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787792, Length=204, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87081782, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787712, Length=197, Percent_Identity=29.4416243654822, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1788450, Length=177, Percent_Identity=27.683615819209, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1786698, Length=199, Percent_Identity=30.1507537688442, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787029, Length=198, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787105, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1786563, Length=172, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994943, Length=194, Percent_Identity=27.8350515463918, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1789751, Length=182, Percent_Identity=28.021978021978, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI48995001, Length=215, Percent_Identity=24.6511627906977, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787041, Length=174, Percent_Identity=30.4597701149425, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789032, Length=179, Percent_Identity=26.8156424581006, Blast_Score=60, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567265, Length=199, Percent_Identity=29.1457286432161, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25146777, Length=200, Percent_Identity=31, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559834, Length=177, Percent_Identity=28.2485875706215, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71988343, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=163, Percent_Identity=31.9018404907975, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=200, Percent_Identity=29, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=200, Percent_Identity=30, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=144, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=201, Percent_Identity=24.8756218905473, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=194, Percent_Identity=27.8350515463918, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555318, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17511077, Length=206, Percent_Identity=25.2427184466019, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567269, Length=194, Percent_Identity=28.8659793814433, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=194, Percent_Identity=27.8350515463918, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=203, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=182, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320339, Length=201, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322980, Length=217, Percent_Identity=26.2672811059908, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641342, Length=189, Percent_Identity=33.8624338624339, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24642252, Length=189, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859989, Length=189, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648314, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007328, Length=154, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28574150, Length=154, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI221512771, Length=191, Percent_Identity=28.2722513089005, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574259, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363262, Length=198, Percent_Identity=30.8080808080808, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=198, Percent_Identity=30.8080808080808, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI85726357, Length=178, Percent_Identity=31.4606741573034, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014769
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR008995
- InterPro:   IPR005666
- InterPro:   IPR013611 [H]

Pfam domain/function: PF00005 ABC_tran; PF08402 TOBE_2 [H]

EC number: =3.6.3.25 [H]

Molecular weight: Translated: 23557; Mature: 23425

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIVKVDVFKKFKNFELKVNFSVNEGEKVLIQGPNGSGKTTLLYLIYGVLNPDSGYVRV
CCCEEEEHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCCEEEEEEEEEEECCCCCEEEE
FNKNPTVELRKSEMYMLEEYLIFLENASLKENLEFITSLRDFNINKTEELINKFDLPLYK
ECCCCCEEEEHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
KSYQLSSGQRRLFKLALAFSAEAKLLLLDEPTSNLDIENSKAVKDMIREYSGTIIFASHD
CCCCCCCCHHHHHHEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECC
LLLKESCDKTIYLRTGKIERIEIK
EEECCCCCCEEEEECCCEEEEEEC
>Mature Secondary Structure 
SEIVKVDVFKKFKNFELKVNFSVNEGEKVLIQGPNGSGKTTLLYLIYGVLNPDSGYVRV
CCEEEEHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCCEEEEEEEEEEECCCCCEEEE
FNKNPTVELRKSEMYMLEEYLIFLENASLKENLEFITSLRDFNINKTEELINKFDLPLYK
ECCCCCEEEEHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
KSYQLSSGQRRLFKLALAFSAEAKLLLLDEPTSNLDIENSKAVKDMIREYSGTIIFASHD
CCCCCCCCHHHHHHEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECC
LLLKESCDKTIYLRTGKIERIEIK
EEECCCCCCEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]