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The map label for this gene is hoxN [H]

Identifier: 15897886

GI number: 15897886

Start: 876820

End: 877941

Strand: Reverse

Name: hoxN [H]

Synonym: SSO1018

Alternate gene names: 15897886

Gene position: 877941-876820 (Counterclockwise)

Preceding gene: 15897888

Following gene: 15897885

Centisome position: 29.34

GC content: 35.12

Gene sequence:

>1122_bases
TTGCTTCAGAATAGTAGAAAAATTTATATGATGGATAGACAATCCATATATGCGATGAGATCCATTCTCAATACGTTAAC
ACAAACAATTAGTTACAAAAATTTAGTCACCTTATCACTTTTCTACGTACTCAACGTATTACTAACAGCATTACTTTTTC
TCTTCCTATACACATTACCGCAAAAACCACTAACATTAAACACAGATAGCGGTGAGCTAATAGGAACCTTCATAACACTA
GGAGTTTTATCATACACCTTTGGCTTAAGACACGCAGTAGACGCTGATCACTTGGCAGCAATAGATAACGTAACTAGGAA
AATGTTACAAGAAGGAAAGAATCCAGTCTTCGTTGGCACTTTCTTCTCATTTGGTCATTCAACAGTAGTAATTTTACTAT
CCCTTGCAGTAATGATGGCTTCAAGGCTGGTAACTAACTCATTACCGTCCCTCGAGAACACCGGAAATTTGATCGAGACA
CTAATAAGTGGAGGATTTCTTTATCTTTTAGGCCTACTAAACACAATAGTATTCTACGAATTATACTCGTTTTATAAAGA
AGGAAAATATGACAAACAAAAACTAGAGGAAATATTACAGAAAAGAGGTTTCATGAATAAATACTTTAACAAGTTGTTCA
AAATAATAACAAACCAATGGCAAATGTACATTGTAGGATTCCTCTTTGGACTAGGATTTGACACCGCGACAGAAGTGGCA
ATACTATCAATATCGGCAATACTATCATCAACGTACATACACATACCAATCTACATAATCTTACTATACCCAATCCTATT
TTCACTAGGAATGTCACTAGTTGACACTACTGATGGTCTATTCATGAGGTTCGCCTATGGCTGGGCATTCCTATCACCAC
TCAGAAAAATATGGTACAACTTAACGATAACACTAATATCAATTTTAATAGCGTTTGGAATAGGTACAATAGAGTTGTTA
GGACTATTACAAGCTGAGTTCAACCTAACTGGATTATTCTGGGATCAAATAGCTGCGTTAAACAACGTTTACTGGGAAAC
AATAGGATATTATGTAATACTAACCTTTGCCATAACTTGGATTGGGTCTGGAATGATTTACAGGATAAAGAAAATAGAGT
AA

Upstream 100 bases:

>100_bases
TTTAATCAAATATTCTACAATTTACAGCATTTTAGGTTATTGAAACCAGTAAAACTTGTACTATAACTTACACAAGACCA
TGAAATAACTGCCTTGTGGA

Downstream 100 bases:

>100_bases
CCACAAAGGGTGAGGCAATTTTCCTCACTAATTCCAAGAATACAGATAGAAGGAGGAATCTTTAAAACAATCTCGAACAC
TAAGTGATGCAAGCACTTTA

Product: high-affinity nickel-transport protein (hoxN)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MLQNSRKIYMMDRQSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTDSGELIGTFITL
GVLSYTFGLRHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTVVILLSLAVMMASRLVTNSLPSLENTGNLIET
LISGGFLYLLGLLNTIVFYELYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVA
ILSISAILSSTYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTITLISILIAFGIGTIELL
GLLQAEFNLTGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRIKKIE

Sequences:

>Translated_373_residues
MLQNSRKIYMMDRQSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTDSGELIGTFITL
GVLSYTFGLRHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTVVILLSLAVMMASRLVTNSLPSLENTGNLIET
LISGGFLYLLGLLNTIVFYELYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVA
ILSISAILSSTYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTITLISILIAFGIGTIELL
GLLQAEFNLTGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRIKKIE
>Mature_373_residues
MLQNSRKIYMMDRQSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLPQKPLTLNTDSGELIGTFITL
GVLSYTFGLRHAVDADHLAAIDNVTRKMLQEGKNPVFVGTFFSFGHSTVVILLSLAVMMASRLVTNSLPSLENTGNLIET
LISGGFLYLLGLLNTIVFYELYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVA
ILSISAILSSTYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYNLTITLISILIAFGIGTIELL
GLLQAEFNLTGLFWDQIAALNNVYWETIGYYVILTFAITWIGSGMIYRIKKIE

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 42461; Mature: 42461

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00079 MULTICOPPER_OXIDASE1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQNSRKIYMMDRQSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLP
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QKPLTLNTDSGELIGTFITLGVLSYTFGLRHAVDADHLAAIDNVTRKMLQEGKNPVFVGT
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEH
FFSFGHSTVVILLSLAVMMASRLVTNSLPSLENTGNLIETLISGGFLYLLGLLNTIVFYE
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
LYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVA
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILSISAILSSTYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LTITLISILIAFGIGTIELLGLLQAEFNLTGLFWDQIAALNNVYWETIGYYVILTFAITW
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGSGMIYRIKKIE
HCCCCEEEEEECC
>Mature Secondary Structure
MLQNSRKIYMMDRQSIYAMRSILNTLTQTISYKNLVTLSLFYVLNVLLTALLFLFLYTLP
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QKPLTLNTDSGELIGTFITLGVLSYTFGLRHAVDADHLAAIDNVTRKMLQEGKNPVFVGT
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEH
FFSFGHSTVVILLSLAVMMASRLVTNSLPSLENTGNLIETLISGGFLYLLGLLNTIVFYE
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
LYSFYKEGKYDKQKLEEILQKRGFMNKYFNKLFKIITNQWQMYIVGFLFGLGFDTATEVA
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILSISAILSSTYIHIPIYIILLYPILFSLGMSLVDTTDGLFMRFAYGWAFLSPLRKIWYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LTITLISILIAFGIGTIELLGLLQAEFNLTGLFWDQIAALNNVYWETIGYYVILTFAITW
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGSGMIYRIKKIE
HCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]