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The map label for this gene is argS

Identifier: 15897753

GI number: 15897753

Start: 733203

End: 735080

Strand: Reverse

Name: argS

Synonym: SSO0857

Alternate gene names: 15897753

Gene position: 735080-733203 (Counterclockwise)

Preceding gene: 15897757

Following gene: 15897750

Centisome position: 24.57

GC content: 34.82

Gene sequence:

>1878_bases
GTGGATATAATAGGAAGAGCTAAGAAAGAATTGGCGGAATATGTCGCTGCACAATTAGGTATAAGCGAGGAGGAAGTCTT
TAAAAATATTACATATCCTCCTAGGGAAGAACTTGGCGACTTATCATTAGCGTTACCATCATTAATAAAGGGAAATATAA
ATGAGAAAGCGAAATTATTACAAGAATATAAAGGTGAGTTAATAGAGAGGATAGAAGTAGCCGGAATATATCTTAATGCG
AGGCTTAATCTAAGAAATATTTTCGTGAGTATCTTTAGCAAACTAGACGATAGTTATGGACTGGAAAAAATCGAAAAGCC
AAAAAGAATAGTAGTTGAACACACGAGCGCTAATCCTATACATCCGTTACATATAGGCCATTTGAGAAATACGATACTTG
GAGATGCGCTTGCTAGAGCGTTAAAAGCTAGAGGTCACTCAGTTAATGTTAGGTTTTACGTTAACGATACTGGGAGGCAA
GTTGCAGTTCTAATTTACGGCCTAAAACTTTTAGGTTTTCCTGATCCAGAGCCAAATGTAAAGAAGGATCTATGGTTGGG
TATAATATATGCCATGACTAATGTAATTTTAGAAATTAGGAAGTTGAGAGAGGAGTTAAAGAAACTTTCAGAGTCAGAGT
ATAGGGAGAAAGTGAGAGAACTAGATGAGCTAATAGTAATAGCGAATGATCTAAGGAATAGAAATGAGGTACTTTTCGAT
AAGTTAGCAGACGCTATAAATGCTAAGGAGGAGCCGGAGAAGGAGATAGGAGAAATCATAAAGAAATACGAAGAGGGTAA
TGATGAACTAAAGGGGATTATTAGAAAGTACATTAGTTATGCGCTAGAAGGCTTTAGTGAAACGTTATCCAAACTTAATA
TAAGATTTGACAATTTCGACTATGAGAGTGACTTGTTATGGGAGAATATGGTTAATGAAGTATTAAAGGCCTTATTGTCT
TCCTCGGCTAAAATACCATATAAGGGAGTAATAGCATTGGACTTAGATAGTTTCTTAGGTGATGAAGCTAGATCTAAGTT
GAGAATTCCAAAAGGGCTCAAGATACCTCCTTTAGTGTTGATGAGATCCGATGGAACTACATTGTATACCGTTAGGGATA
TTGCGTATACAATTTTCAAATTTAATCAGTTTAATGCAGATTTTGTTATAAATGTGATCGCAGAAGAACAATACATTCCG
CAAATACAATTAAGAGGTGCTCTAGAGTTACTCGGATATTCGAGATTTGCGGAAAATTTATTGCATTATTCATATGGGAT
GGTTAACATCCAAGGACTAAGAATGAGTGGAAGACTAGGAAAGATAATAACCATTGACGAGATATATGAAAAACTAGATA
ACATAGTTAGAAATAAGCTGAAAGAGAAAGGTGGTAATATGGAAAATATTGATGATATAGCAAATGCAGCGCTTAGATAC
GCAATTTTGTCAGTTTCTGCAAATAAGCCTTTATCATTTGATTTAAACAGGATAACCAGCTTTGAGCAGAACAGTGGACC
TTATTTACAATATACTTATGCTAGAGCTGCTAACATATTAGCTAAATCTACTGAAAACTTATCTATGGATAAGGTAGACT
TTAGTGATTTAGTTGGAGATAAGAGGAACATATTAATCTTGATAGCTAAATTCCCCGAGGTATTCAAGAATGCTGTAGAT
AACTTAAGGTTAGAAGATTTAGTAGCGTTTCTGAGAGAATTATCTGACATATTCAATAGTTGGTATGATAAAGAGAGAGT
ACTACAAGAACAAGATCCAAGGAAGAGAATGTTAAGATTATATATAGTAAAAGGAGTGTCAGTTGTATTAAAGAACGGGT
TAAGCGTCTTAGGTATAAGGAGCTTAGAAAGGATGTAA

Upstream 100 bases:

>100_bases
TTCCACTATAATCCTCTACTATTAGGATTTCCACCCTTTTCTTCATGGTTATATGATTCTAGTGAGTAAATATTAAAAGT
TATAAGGCATAAAACGTGAT

Downstream 100 bases:

>100_bases
TTAGTTAAAATGAAATACAGAGGATATTTTTCTAACTGGTAGATATTAATCATTAATATAGACATCACTAGAGTTTTGTC
ACTGATAATATTTTGAAGTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKGNINEKAKLLQEYKGELIERIEVAGIYLNA
RLNLRNIFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPIHPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQ
VAVLIYGLKLLGFPDPEPNVKKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFDYESDLLWENMVNEVLKALLS
SSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVLMRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIP
QIQLRGALELLGYSRFAENLLHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGDKRNILILIAKFPEVFKNAVD
NLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRLYIVKGVSVVLKNGLSVLGIRSLERM

Sequences:

>Translated_625_residues
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKGNINEKAKLLQEYKGELIERIEVAGIYLNA
RLNLRNIFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPIHPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQ
VAVLIYGLKLLGFPDPEPNVKKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFDYESDLLWENMVNEVLKALLS
SSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVLMRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIP
QIQLRGALELLGYSRFAENLLHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGDKRNILILIAKFPEVFKNAVD
NLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRLYIVKGVSVVLKNGLSVLGIRSLERM
>Mature_625_residues
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKGNINEKAKLLQEYKGELIERIEVAGIYLNA
RLNLRNIFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPIHPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQ
VAVLIYGLKLLGFPDPEPNVKKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFDYESDLLWENMVNEVLKALLS
SSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVLMRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIP
QIQLRGALELLGYSRFAENLLHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGDKRNILILIAKFPEVFKNAVD
NLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRLYIVKGVSVVLKNGLSVLGIRSLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=649, Percent_Identity=25.2696456086287, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI15149476, Length=305, Percent_Identity=23.6065573770492, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1788184, Length=576, Percent_Identity=24.1319444444444, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71985061, Length=648, Percent_Identity=22.2222222222222, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320548, Length=638, Percent_Identity=25.8620689655172, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321883, Length=609, Percent_Identity=26.6009852216749, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI28571570, Length=410, Percent_Identity=23.1707317073171, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_SULSO (Q97ZN1)

Other databases:

- EMBL:   AE006641
- PIR:   E90236
- RefSeq:   NP_342358.1
- ProteinModelPortal:   Q97ZN1
- GeneID:   1455115
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0857
- NMPDR:   fig|273057.1.peg.781
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- PhylomeDB:   Q97ZN1
- ProtClustDB:   PRK01611
- BioCyc:   SSOL273057:SSO0857-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 71388; Mature: 71388

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKGNINEKAKLL
CCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHH
QEYKGELIERIEVAGIYLNARLNLRNIFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPI
HHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHCHHCCHHHHCCCCEEEEEECCCCCC
HPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQVAVLIYGLKLLGFPDPEPNV
CCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCC
KKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFD
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC
YESDLLWENMVNEVLKALLSSSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCHHHHHHCCCCCCCCCCCEEE
MRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIPQIQLRGALELLGYSRFAENL
EECCCCEEEEHHHHHHHHHHHCCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHH
LHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
HHHHCCEEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGD
HHHEECCCCCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHCCC
KRNILILIAKFPEVFKNAVDNLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRL
CCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YIVKGVSVVLKNGLSVLGIRSLERM
HHHHHHHHHHHCCCHHEEHHHHHCC
>Mature Secondary Structure
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKGNINEKAKLL
CCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHH
QEYKGELIERIEVAGIYLNARLNLRNIFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPI
HHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHCHHCCHHHHCCCCEEEEEECCCCCC
HPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQVAVLIYGLKLLGFPDPEPNV
CCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCC
KKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFD
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC
YESDLLWENMVNEVLKALLSSSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCHHHHHHCCCCCCCCCCCEEE
MRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIPQIQLRGALELLGYSRFAENL
EECCCCEEEEHHHHHHHHHHHCCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHH
LHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
HHHHCCEEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGD
HHHEECCCCCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHCCC
KRNILILIAKFPEVFKNAVDNLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRL
CCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YIVKGVSVVLKNGLSVLGIRSLERM
HHHHHHHHHHHCCCHHEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726