Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 15889977

GI number: 15889977

Start: 2710791

End: 2711591

Strand: Reverse

Name: glpR [H]

Synonym: Atu2725

Alternate gene names: 15889977

Gene position: 2711591-2710791 (Counterclockwise)

Preceding gene: 159185349

Following gene: 159185348

Centisome position: 95.43

GC content: 61.3

Gene sequence:

>801_bases
ATGAGTGATCATTTTGTCAGTGAGCGGCAGGCGCTCATCCTAGCGCAGTTGCGGCAAAGTGGCCGTGTGCTGGCGCAGGA
TCTGGCCCAGAATTTCGGCGTTTCCGAAGACACGGTGCGCCGCGACCTGCGCGAGATGGCAGCGCGGGGGGAATGCCTTC
GCGTTTATGGCGGAGCGCTGCTTTCCGACAGCACGACAGTACCGCTCAAAACCCGGATTACCGAGGATGCTGACCGCAAG
GCCACGCTGGCGCGTGCCGTCGTTCCGCTCATTGAACCGGGCATGGTGGTTTTCATCGATGCCGGATCGACCAATCTTGC
CATTGCACGAGCGATACCGGCCGGGCTCAATCTGACCGTGGTGACGAATACGCCCGCCATAGCCGCCGATCTGACGGGGC
GTGCCGATATCGATCTGGTGCTGATTGGCGGCAAGGTCGATCCTGCCGTGGGTGCGGCGATCGATGCGATGGCGCTTCGG
CAGCTTGAACTGATGCGGCCCGATCTGTGCGTGCTCGGTGTTTGCGGCGTTGCGGCCGAGACGGGCCTTTCGGCGGATGT
TTTCGAGGATGCGGTGTTCAAGCGGCTTGCCTGCAGTGCCAGCCAGCGGGTCATCGCCGCCATCACCACGGAAAAGCTCG
GCCATAAGGCTGCTTTCCACGTCCATGATTTTTCCCCACCGCTTTGCCTCGTGCTGGAACGGGATGCCGACCGTGCATTG
GTCGAGTCGCTTTCGGCACAAGGCGTAGACGTTTATTGCGGCGAAGATGACGCTGCCCCGTTTTCTCATGGTCAAGTCTG
A

Upstream 100 bases:

>100_bases
CAGATGCCCGCCTTCCCGGCGGGCGTTTTTTATTGCGCTCCGGCGGAAACTTGATTATGCATGTTTGTGCACGTTTATTC
TTGTTTACGCATGAGTCCCG

Downstream 100 bases:

>100_bases
AGGATATTGCCGATGAATGGCCCCACGACATTTTCACCGACAGGCACTCGCTCATCCTATCTGACGCGGCACAGGCTTGG
CGTTTCGCTGCTGTTTTTGA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSDHFVSERQALILAQLRQSGRVLAQDLAQNFGVSEDTVRRDLREMAARGECLRVYGGALLSDSTTVPLKTRITEDADRK
ATLARAVVPLIEPGMVVFIDAGSTNLAIARAIPAGLNLTVVTNTPAIAADLTGRADIDLVLIGGKVDPAVGAAIDAMALR
QLELMRPDLCVLGVCGVAAETGLSADVFEDAVFKRLACSASQRVIAAITTEKLGHKAAFHVHDFSPPLCLVLERDADRAL
VESLSAQGVDVYCGEDDAAPFSHGQV

Sequences:

>Translated_266_residues
MSDHFVSERQALILAQLRQSGRVLAQDLAQNFGVSEDTVRRDLREMAARGECLRVYGGALLSDSTTVPLKTRITEDADRK
ATLARAVVPLIEPGMVVFIDAGSTNLAIARAIPAGLNLTVVTNTPAIAADLTGRADIDLVLIGGKVDPAVGAAIDAMALR
QLELMRPDLCVLGVCGVAAETGLSADVFEDAVFKRLACSASQRVIAAITTEKLGHKAAFHVHDFSPPLCLVLERDADRAL
VESLSAQGVDVYCGEDDAAPFSHGQV
>Mature_265_residues
SDHFVSERQALILAQLRQSGRVLAQDLAQNFGVSEDTVRRDLREMAARGECLRVYGGALLSDSTTVPLKTRITEDADRKA
TLARAVVPLIEPGMVVFIDAGSTNLAIARAIPAGLNLTVVTNTPAIAADLTGRADIDLVLIGGKVDPAVGAAIDAMALRQ
LELMRPDLCVLGVCGVAAETGLSADVFEDAVFKRLACSASQRVIAAITTEKLGHKAAFHVHDFSPPLCLVLERDADRALV
ESLSAQGVDVYCGEDDAAPFSHGQV

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=212, Percent_Identity=31.6037735849057, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=28.9156626506024, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789170, Length=201, Percent_Identity=29.3532338308458, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789059, Length=246, Percent_Identity=26.8292682926829, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787540, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=26.8518518518519, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787063, Length=216, Percent_Identity=28.7037037037037, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790635, Length=248, Percent_Identity=21.7741935483871, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=25.3968253968254, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788069, Length=216, Percent_Identity=22.6851851851852, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28115; Mature: 27983

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHFVSERQALILAQLRQSGRVLAQDLAQNFGVSEDTVRRDLREMAARGECLRVYGGAL
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCEE
LSDSTTVPLKTRITEDADRKATLARAVVPLIEPGMVVFIDAGSTNLAIARAIPAGLNLTV
ECCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCEEEE
VTNTPAIAADLTGRADIDLVLIGGKVDPAVGAAIDAMALRQLELMRPDLCVLGVCGVAAE
EECCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHH
TGLSADVFEDAVFKRLACSASQRVIAAITTEKLGHKAAFHVHDFSPPLCLVLERDADRAL
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCEEEEEEECCCCCEEEEEECCCHHHH
VESLSAQGVDVYCGEDDAAPFSHGQV
HHHHCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SDHFVSERQALILAQLRQSGRVLAQDLAQNFGVSEDTVRRDLREMAARGECLRVYGGAL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCEE
LSDSTTVPLKTRITEDADRKATLARAVVPLIEPGMVVFIDAGSTNLAIARAIPAGLNLTV
ECCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCEEEE
VTNTPAIAADLTGRADIDLVLIGGKVDPAVGAAIDAMALRQLELMRPDLCVLGVCGVAAE
EECCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHH
TGLSADVFEDAVFKRLACSASQRVIAAITTEKLGHKAAFHVHDFSPPLCLVLERDADRAL
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCEEEEEEECCCCCEEEEEECCCHHHH
VESLSAQGVDVYCGEDDAAPFSHGQV
HHHHCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]