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The map label for this gene is sucC

Identifier: 15889893

GI number: 15889893

Start: 2623568

End: 2624761

Strand: Reverse

Name: sucC

Synonym: Atu2638

Alternate gene names: 15889893

Gene position: 2624761-2623568 (Counterclockwise)

Preceding gene: 159185305

Following gene: 15889892

Centisome position: 92.37

GC content: 59.13

Gene sequence:

>1194_bases
ATGAATATTCACGAATATCAGGCTAAGGCTCTTCTGAAGGGCTACGGCGCGCCGGTTGCTGAAGGCGTCGCCATCCTCAA
GGTCGAAGAAGCCGAAGCTGCCGCAAAGCAGCTTCCCGGCCCGCTTTACGTCGTCAAGAGCCAGATTCACGCTGGCGGTC
GCGGCAAGGGCAAGTTCAAGGAGCTCGGCCCCGACGCCAAGGGCGGCGTTCGCCTAGCGAAGTCGATCGAGGAAGTCGTT
TCTCATTCCAGGGACATGCTCGGCAACACGCTGGTAACGGCGCAGACGGGCGACGCCGGCAAACAGGTCAACCGCCTCTA
CATCGAAGACGGTGCGGACATTGCCCGCGAACTCTATTGCTCGCTTCTGGTTGACCGTTCGGTCGGTCAGGTCGCATTCG
TGGTTTCCACTGAAGGCGGCATGGATATCGAAGCTGTCGCCCATGACACGCCGGAAAAGATCCACACCATCGCCATCAAC
CCGGAAAAGGGCGTGAGCGACGCTGACGTTGCCGCAATCTCCAAGGCTCTCGAGCTTGATGGTGTTGCAGCCGAAGACGC
CAAAGCGCTGTTCCCGATCCTCTACAAGGCCTTCAACGAGAAGGACATGGCTCTCCTCGAGGTTAACCCGCTGATCGTCA
TGGAAAATGGCCATCTGCGCGTTCTCGACGCCAAGATGTCCTTCGACGGCAACGCGCTGTTCCGCCATGAAGACGTCAAG
GCGCTGCGCGACGAGACCGAAGAAGACGCCAAGGAAATCGAAGCCTCCAAGTGGGACCTCGCTTACGTGGCGCTCGACGG
CAACATCGGCTGCATGGTCAATGGTGCCGGTCTCGCCATGGCGACGATGGACATCATCAAGCTTTACGGCAAAGAGCCGG
CAAACTTCTGTGACGTCGGCGGCGGCGCCGGCAAGGAGAAGGTTGCGGCAGCTTTCAAGATCATTACGGCTGACCCGAAG
GTCGAGGGTATCCTCGTCAACATCTTCGGCGGCATCATGAAGTGCGACGTCATCGCCGAAGGTGTTATCGCCGCGGTGAA
GGAAGTCGGTTTGCAGGTTCCGCTCGTTGTTCGCCTCGAAGGCACCAACGTCGAACTTGGCAAGAAGCTCCTGAACGAAT
CGGGCCTTGCGATTACGGCTGCTGACGACCTGGACGACGCAGCCAAGAAGATCGTCGCGGCGATCAACGGCTAA

Upstream 100 bases:

>100_bases
GAAATCCGTCGGCGCTGTCGCTGGTCTTTGCGAAGCCTGCATCAACATCGCTCCGTCGCTGAAGTAATAACTTCAAGCGG
TTCCAAACAGGGATTATTCC

Downstream 100 bases:

>100_bases
TTGAGGGACCGGAAATAATGTCTATTCTTGTTAATAAAGACACCAAGATCCTCGTTCAGGGTCTGACCGGCAAGACCGGC
ACCTTCCACACCGAACAGGC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAEAAAKQLPGPLYVVKSQIHAGGRGKGKFKELGPDAKGGVRLAKSIEEVV
SHSRDMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYCSLLVDRSVGQVAFVVSTEGGMDIEAVAHDTPEKIHTIAIN
PEKGVSDADVAAISKALELDGVAAEDAKALFPILYKAFNEKDMALLEVNPLIVMENGHLRVLDAKMSFDGNALFRHEDVK
ALRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVGGGAGKEKVAAAFKIITADPK
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLQVPLVVRLEGTNVELGKKLLNESGLAITAADDLDDAAKKIVAAING

Sequences:

>Translated_397_residues
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAEAAAKQLPGPLYVVKSQIHAGGRGKGKFKELGPDAKGGVRLAKSIEEVV
SHSRDMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYCSLLVDRSVGQVAFVVSTEGGMDIEAVAHDTPEKIHTIAIN
PEKGVSDADVAAISKALELDGVAAEDAKALFPILYKAFNEKDMALLEVNPLIVMENGHLRVLDAKMSFDGNALFRHEDVK
ALRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVGGGAGKEKVAAAFKIITADPK
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLQVPLVVRLEGTNVELGKKLLNESGLAITAADDLDDAAKKIVAAING
>Mature_397_residues
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAEAAAKQLPGPLYVVKSQIHAGGRGKGKFKELGPDAKGGVRLAKSIEEVV
SHSRDMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYCSLLVDRSVGQVAFVVSTEGGMDIEAVAHDTPEKIHTIAIN
PEKGVSDADVAAISKALELDGVAAEDAKALFPILYKAFNEKDMALLEVNPLIVMENGHLRVLDAKMSFDGNALFRHEDVK
ALRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVGGGAGKEKVAAAFKIITADPK
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLQVPLVVRLEGTNVELGKKLLNESGLAITAADDLDDAAKKIVAAING

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=46.1139896373057, Blast_Score=316, Evalue=2e-86,
Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=43.3673469387755, Blast_Score=316, Evalue=3e-86,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=45.2054794520548, Blast_Score=291, Evalue=1e-78,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=51.3853904282116, Blast_Score=380, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17539378, Length=399, Percent_Identity=44.1102756892231, Blast_Score=328, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=43.0379746835443, Blast_Score=298, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=43.5443037974684, Blast_Score=324, Evalue=1e-89,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=48.2412060301507, Blast_Score=358, Evalue=3e-99,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=46.6494845360825, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=46.6494845360825, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=46.7866323907455, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=46.7866323907455, Blast_Score=319, Evalue=2e-87,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_AGRT5 (Q8UC60)

Other databases:

- EMBL:   AE007869
- PIR:   AE2900
- PIR:   F97675
- RefSeq:   NP_355574.1
- ProteinModelPortal:   Q8UC60
- SMR:   Q8UC60
- STRING:   Q8UC60
- GeneID:   1134676
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2638
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- PhylomeDB:   Q8UC60
- ProtClustDB:   PRK00696
- BioCyc:   ATUM176299-1:ATU2638-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41900; Mature: 41900

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAEAAAKQLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHCCCCHHCCEEEEEEEHHHHHHHHCCCCEEEEEHHHCCCCCCCCCHH
ELGPDAKGGVRLAKSIEEVVSHSRDMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYC
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEECCHHHHHHHHH
SLLVDRSVGQVAFVVSTEGGMDIEAVAHDTPEKIHTIAINPEKGVSDADVAAISKALELD
HHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
GVAAEDAKALFPILYKAFNEKDMALLEVNPLIVMENGHLRVLDAKMSFDGNALFRHEDVK
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCEEEEEEEECCCCCEEEEHHHHH
ALRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVG
HHHCCCHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEECCC
GGAGKEKVAAAFKIITADPKVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLQVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKLLNESGLAITAADDLDDAAKKIVAAING
CCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAEAAAKQLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHCCCCHHCCEEEEEEEHHHHHHHHCCCCEEEEEHHHCCCCCCCCCHH
ELGPDAKGGVRLAKSIEEVVSHSRDMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYC
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEECCHHHHHHHHH
SLLVDRSVGQVAFVVSTEGGMDIEAVAHDTPEKIHTIAINPEKGVSDADVAAISKALELD
HHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
GVAAEDAKALFPILYKAFNEKDMALLEVNPLIVMENGHLRVLDAKMSFDGNALFRHEDVK
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCEEEEEEEECCCCCEEEEHHHHH
ALRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVG
HHHCCCHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEECCC
GGAGKEKVAAAFKIITADPKVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLQVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKLLNESGLAITAADDLDDAAKKIVAAING
CCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194