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The map label for this gene is sucD [H]

Identifier: 15889892

GI number: 15889892

Start: 2622648

End: 2623550

Strand: Reverse

Name: sucD [H]

Synonym: Atu2637

Alternate gene names: 15889892

Gene position: 2623550-2622648 (Counterclockwise)

Preceding gene: 15889893

Following gene: 159185304

Centisome position: 92.33

GC content: 61.46

Gene sequence:

>903_bases
ATGTCTATTCTTGTTAATAAAGACACCAAGATCCTCGTTCAGGGTCTGACCGGCAAGACCGGCACCTTCCACACCGAACA
GGCGCTTGCTTATTACGGCACGCAGATGGTCGGCGGTATTCACCCGAAGAAGGGTGGCGAAACCTGGACCGGTTCCAAGG
GCGAAAGCCTGCCGATCTTCGCAACGGTTGCCGAAGCCAAGGAAAAGACCGGTGCAGATGCATCCGTGATCTATGTTCCG
CCGGCAGGTGCAGCAGACGCGATCATCGAAGCCATCGAGGCTGAGATCCCGTTCATCACCTGCATCACCGAAGGCATCCC
GGTCATGGACATGGTGCGCGTCAAGGCCCGCCTCGACCGCTCCAAGTCGCGCCTGCTCGGCCCGAACTGCCCCGGCATCA
TGACGCCGGAAGAATGCAAGATCGGCATCATGCCGGGCTCCATCTTCCGCAAGGGTTCGGTCGGTATCGTTTCGCGCTCC
GGCACGCTCACCTATGAAGCCGTGTTCCAGACCTCGAACGAAGGCCTCGGCCAGACGACCGCTGTCGGCATCGGCGGCGA
CCCGGTCAAGGGTACCGAGTTCATCGACATCCTGGAAATGTTCCTGGCCGACGACGCCACCCAGTCGATCATCATGATCG
GCGAAATCGGCGGTTCGGCTGAAGAAGATGCGGCGCAGTTCCTGATCGATGAAGCCAAGAAGGGCCGCAAGAAGCCGATG
GCCGGCTTCATCGCGGGCCGTACGGCTCCGAAGGGCCGCACCATGGGCCATGCCGGCGCTGTCGTTTCTGGCGGCAAGGG
CGACGCAGAGTCCAAGATCGCAGCCATGGAAGCGGCGGGCATCAAGGTTTCGCCTTCCCCGGCGCGCCTCGGCAAGACGC
TGGTTGAAGTCCTCAAGGGCTGA

Upstream 100 bases:

>100_bases
TGAACGAATCGGGCCTTGCGATTACGGCTGCTGACGACCTGGACGACGCAGCCAAGAAGATCGTCGCGGCGATCAACGGC
TAATTGAGGGACCGGAAATA

Downstream 100 bases:

>100_bases
GACCACATGAGACCGGTAACGGGCGGCGCGGTTTTAACGCTGCGCTGCCCGATGCCGCAAGAAGATAGACAGACGGCATA
CCGCCCTGGCGGCAGACAGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSILVNKDTKILVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWTGSKGESLPIFATVAEAKEKTGADASVIYVP
PAGAADAIIEAIEAEIPFITCITEGIPVMDMVRVKARLDRSKSRLLGPNCPGIMTPEECKIGIMPGSIFRKGSVGIVSRS
GTLTYEAVFQTSNEGLGQTTAVGIGGDPVKGTEFIDILEMFLADDATQSIIMIGEIGGSAEEDAAQFLIDEAKKGRKKPM
AGFIAGRTAPKGRTMGHAGAVVSGGKGDAESKIAAMEAAGIKVSPSPARLGKTLVEVLKG

Sequences:

>Translated_300_residues
MSILVNKDTKILVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWTGSKGESLPIFATVAEAKEKTGADASVIYVP
PAGAADAIIEAIEAEIPFITCITEGIPVMDMVRVKARLDRSKSRLLGPNCPGIMTPEECKIGIMPGSIFRKGSVGIVSRS
GTLTYEAVFQTSNEGLGQTTAVGIGGDPVKGTEFIDILEMFLADDATQSIIMIGEIGGSAEEDAAQFLIDEAKKGRKKPM
AGFIAGRTAPKGRTMGHAGAVVSGGKGDAESKIAAMEAAGIKVSPSPARLGKTLVEVLKG
>Mature_299_residues
SILVNKDTKILVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWTGSKGESLPIFATVAEAKEKTGADASVIYVPP
AGAADAIIEAIEAEIPFITCITEGIPVMDMVRVKARLDRSKSRLLGPNCPGIMTPEECKIGIMPGSIFRKGSVGIVSRSG
TLTYEAVFQTSNEGLGQTTAVGIGGDPVKGTEFIDILEMFLADDATQSIIMIGEIGGSAEEDAAQFLIDEAKKGRKKPMA
GFIAGRTAPKGRTMGHAGAVVSGGKGDAESKIAAMEAAGIKVSPSPARLGKTLVEVLKG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=295, Percent_Identity=63.3898305084746, Blast_Score=307, Evalue=8e-84,
Organism=Homo sapiens, GI38569421, Length=317, Percent_Identity=26.813880126183, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38569423, Length=317, Percent_Identity=26.813880126183, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786949, Length=299, Percent_Identity=59.866220735786, Blast_Score=344, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17553126, Length=300, Percent_Identity=59.6666666666667, Blast_Score=333, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI17550194, Length=300, Percent_Identity=58, Blast_Score=331, Evalue=4e-91,
Organism=Caenorhabditis elegans, GI17551266, Length=311, Percent_Identity=27.9742765273312, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17557344, Length=318, Percent_Identity=26.4150943396226, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=301, Percent_Identity=52.8239202657807, Blast_Score=285, Evalue=8e-78,
Organism=Drosophila melanogaster, GI21356559, Length=296, Percent_Identity=58.1081081081081, Blast_Score=347, Evalue=8e-96,
Organism=Drosophila melanogaster, GI28574296, Length=299, Percent_Identity=60.8695652173913, Blast_Score=318, Evalue=3e-87,
Organism=Drosophila melanogaster, GI281363477, Length=279, Percent_Identity=27.9569892473118, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363475, Length=279, Percent_Identity=27.9569892473118, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363473, Length=279, Percent_Identity=27.9569892473118, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31126; Mature: 30995

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVNKDTKILVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWTGSKGESLPIF
CEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
ATVAEAKEKTGADASVIYVPPAGAADAIIEAIEAEIPFITCITEGIPVMDMVRVKARLDR
EEHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
SKSRLLGPNCPGIMTPEECKIGIMPGSIFRKGSVGIVSRSGTLTYEAVFQTSNEGLGQTT
HHHHCCCCCCCCCCCCCCCEEEECCCHHCCCCCCEEEECCCCEEEEEEEECCCCCCCCEE
AVGIGGDPVKGTEFIDILEMFLADDATQSIIMIGEIGGSAEEDAAQFLIDEAKKGRKKPM
EEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
AGFIAGRTAPKGRTMGHAGAVVSGGKGDAESKIAAMEAAGIKVSPSPARLGKTLVEVLKG
HHEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILVNKDTKILVQGLTGKTGTFHTEQALAYYGTQMVGGIHPKKGGETWTGSKGESLPIF
EEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
ATVAEAKEKTGADASVIYVPPAGAADAIIEAIEAEIPFITCITEGIPVMDMVRVKARLDR
EEHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
SKSRLLGPNCPGIMTPEECKIGIMPGSIFRKGSVGIVSRSGTLTYEAVFQTSNEGLGQTT
HHHHCCCCCCCCCCCCCCCEEEECCCHHCCCCCCEEEECCCCEEEEEEEECCCCCCCCEE
AVGIGGDPVKGTEFIDILEMFLADDATQSIIMIGEIGGSAEEDAAQFLIDEAKKGRKKPM
EEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
AGFIAGRTAPKGRTMGHAGAVVSGGKGDAESKIAAMEAAGIKVSPSPARLGKTLVEVLKG
HHEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]