Click here to switch to the map view.

The map label for this gene is nagK [H]

Identifier: 15889865

GI number: 15889865

Start: 2587873

End: 2588799

Strand: Direct

Name: nagK [H]

Synonym: Atu2609

Alternate gene names: 15889865

Gene position: 2587873-2588799 (Clockwise)

Preceding gene: 15889864

Following gene: 15889868

Centisome position: 91.07

GC content: 62.24

Gene sequence:

>927_bases
ATGATCGTTTGTTTCGATATTGGCGGAACGACCATCAAGGGCGCGATTGCCCATACCCCGGACGACATTCGCCCCGTGCC
ACGCATACCAACGCCGAAAACCAGTTTCGAAGACTTCGCCGCCGGCCTCAAATCCGTCATCGATGCGAGCGGCGGCACGC
CCGGTTGCGTTTCGTTGTCGATTGCCGGGGTCATCGATCCCGACACCGGCAAGGCCACCGTTGCCAATATTCCGAGCATT
CATGGCCGGGTCTTGAAGGACGAGTTGGAAAAAGCCCTCAACCTTCCCGTCATCGTGTCCAATGACGCGGATTGTTTCGT
GATCGCCGAATCGGAAATCGGCTCGGGTCAAGGCCACCGCGTGGTTTTCGGCGTCATCCTTGGAACCGGTGTCGGCGGCG
GGCTGGTGATCGACGGCAAGCTCATCAACAGCCATGGCGGTTTTGCCGGCGAATGGGGGCATGGTCCCGTGGCCGCGACA
TCGGCCGGCAATCCGCCGGTCTCGCTGCCCCGCTTCGAATGCGGCTGTGGCCTCACCGGCTGTGTCGACGCCATCGGCAG
CGCCCGCGGCATGGAAAAGCTGCATGCGCATCTGCACCGGCAGGAGATGACGAGCGAGGATATTATCGCCGCCTGGCAGG
CGGGCGATGCAAAAGCCGCCAGAACCATCGATGTCCTCATCGATATTCTCGCCTCGCCGCTGGCGATGGTGATCAATGTT
ACCGGCGCGACCATTGTGCCGGTGGGCGGCGGGCTTTCGAACTCGCGGGAGCTTCTCGCTGCATTGGATGAAGCAGTCAG
GGGCCGCATTCTCCGGCGCTTCAACCGTCCACTGGTCGTGCCCGCCATCTGCCGCATCGAGCCGGGGCTGATCGGATCAG
CCGTTATCGGGTTGAAATATGCGCAGGAGATCGCCCGCCCGTCCTGA

Upstream 100 bases:

>100_bases
CGATGCCGATTTTGTTGTGCTGACGCCCGGCCTCCAGATGCATTCGACCTGGATTGGCGGAGAAAAAACCTACGATGCCG
TGCATTCCGGAGTGTGAACC

Downstream 100 bases:

>100_bases
TGGCTCTCACGGCGTCTCAATCTTTTCCCGACGGAAACCCAGCCCCACCAGCCGGCCAGTCAGATGGGAAAGAAGCGGAA
ATCGAATAATCGCCCGCACG

Product: ROK family transcriptional regulator

Products: NA

Alternate protein names: GlcNAc kinase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MIVCFDIGGTTIKGAIAHTPDDIRPVPRIPTPKTSFEDFAAGLKSVIDASGGTPGCVSLSIAGVIDPDTGKATVANIPSI
HGRVLKDELEKALNLPVIVSNDADCFVIAESEIGSGQGHRVVFGVILGTGVGGGLVIDGKLINSHGGFAGEWGHGPVAAT
SAGNPPVSLPRFECGCGLTGCVDAIGSARGMEKLHAHLHRQEMTSEDIIAAWQAGDAKAARTIDVLIDILASPLAMVINV
TGATIVPVGGGLSNSRELLAALDEAVRGRILRRFNRPLVVPAICRIEPGLIGSAVIGLKYAQEIARPS

Sequences:

>Translated_308_residues
MIVCFDIGGTTIKGAIAHTPDDIRPVPRIPTPKTSFEDFAAGLKSVIDASGGTPGCVSLSIAGVIDPDTGKATVANIPSI
HGRVLKDELEKALNLPVIVSNDADCFVIAESEIGSGQGHRVVFGVILGTGVGGGLVIDGKLINSHGGFAGEWGHGPVAAT
SAGNPPVSLPRFECGCGLTGCVDAIGSARGMEKLHAHLHRQEMTSEDIIAAWQAGDAKAARTIDVLIDILASPLAMVINV
TGATIVPVGGGLSNSRELLAALDEAVRGRILRRFNRPLVVPAICRIEPGLIGSAVIGLKYAQEIARPS
>Mature_308_residues
MIVCFDIGGTTIKGAIAHTPDDIRPVPRIPTPKTSFEDFAAGLKSVIDASGGTPGCVSLSIAGVIDPDTGKATVANIPSI
HGRVLKDELEKALNLPVIVSNDADCFVIAESEIGSGQGHRVVFGVILGTGVGGGLVIDGKLINSHGGFAGEWGHGPVAAT
SAGNPPVSLPRFECGCGLTGCVDAIGSARGMEKLHAHLHRQEMTSEDIIAAWQAGDAKAARTIDVLIDILASPLAMVINV
TGATIVPVGGGLSNSRELLAALDEAVRGRILRRFNRPLVVPAICRIEPGLIGSAVIGLKYAQEIARPS

Specific function: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NagK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787363, Length=292, Percent_Identity=31.5068493150685, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87081733, Length=277, Percent_Identity=27.4368231046931, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786891, Length=235, Percent_Identity=23.8297872340426, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787878, Length=239, Percent_Identity=23.4309623430962, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.59 [H]

Molecular weight: Translated: 31661; Mature: 31661

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVCFDIGGTTIKGAIAHTPDDIRPVPRIPTPKTSFEDFAAGLKSVIDASGGTPGCVSLS
CEEEEECCCCEEECEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
IAGVIDPDTGKATVANIPSIHGRVLKDELEKALNLPVIVSNDADCFVIAESEIGSGQGHR
EEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCCCCE
VVFGVILGTGVGGGLVIDGKLINSHGGFAGEWGHGPVAATSAGNPPVSLPRFECGCGLTG
EEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHH
CVDAIGSARGMEKLHAHLHRQEMTSEDIIAAWQAGDAKAARTIDVLIDILASPLAMVINV
HHHHHHHHCCHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEC
TGATIVPVGGGLSNSRELLAALDEAVRGRILRRFNRPLVVPAICRIEPGLIGSAVIGLKY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHEECCCCCHHHHHHHHHH
AQEIARPS
HHHHCCCC
>Mature Secondary Structure
MIVCFDIGGTTIKGAIAHTPDDIRPVPRIPTPKTSFEDFAAGLKSVIDASGGTPGCVSLS
CEEEEECCCCEEECEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
IAGVIDPDTGKATVANIPSIHGRVLKDELEKALNLPVIVSNDADCFVIAESEIGSGQGHR
EEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCCCCE
VVFGVILGTGVGGGLVIDGKLINSHGGFAGEWGHGPVAATSAGNPPVSLPRFECGCGLTG
EEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHH
CVDAIGSARGMEKLHAHLHRQEMTSEDIIAAWQAGDAKAARTIDVLIDILASPLAMVINV
HHHHHHHHCCHHHHHHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHEEEEC
TGATIVPVGGGLSNSRELLAALDEAVRGRILRRFNRPLVVPAICRIEPGLIGSAVIGLKY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHEECCCCCHHHHHHHHHH
AQEIARPS
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA