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The map label for this gene is nagA [H]

Identifier: 15889864

GI number: 15889864

Start: 2586703

End: 2587869

Strand: Direct

Name: nagA [H]

Synonym: Atu2608

Alternate gene names: 15889864

Gene position: 2586703-2587869 (Clockwise)

Preceding gene: 15889863

Following gene: 15889865

Centisome position: 91.03

GC content: 60.58

Gene sequence:

>1167_bases
ATGAGCGGCATCAAGGCATTTGTTGGCGCCCGCATTTTCGACGGCGCCGCATGGCACGAGGGCAGAGTGCTCGTGGTCGG
TGACGGGCATGTCACCGCCATCTCAGATAGCGTGCCAGCCGAAGCCGAGATGATCGATGTAAAGGGACTGCTGATCGCGC
CTGGATTCATCGATCTCCAGGTCAATGGCGGCGGCGGGGTGATGTTCAACAACCAGCCGGATGTCGAAGGCATTGCCCGC
ATCTGTTCCGCTCACGCCAGGTTCGGCACGACGGCGCTGATGGTCACGCTCATTACCGACCGGCCGGATGTAATCTCGAA
AGCAGCGCAGGCGGGTATTGCCGCCAGCAAGAAGCAGGTGCCGGGCTTTCTGGGCCTGCATTTCGAAGGGCCGCATCTTT
CCGTCGCACGCAAGGGCACCCATGATCCAGCGCTGGTCCGCAAGATGGAGACGGCCGATCTTGCCGTTCTGATCGGCTGC
AAGGCGGAACTGGCCTTCGTGATGACGACCATTGCCCCTGAGAACGTCACCGAGGAACAGGTCGCAGCGCTGAGAAAAGC
CGGCATCGTGGTCAGTCTCGGCCATACCGATACCGGCCTTGATGTTGCGACGGCCTATATCGAGGCCGGCGCTTCCATGG
TGACACATCTTTTTAACGCCATGAGCCCGCTTGGCCATCGCGAACCGGGTCTGGTTGGCGCCGCCCTTTCGAATGGCGGG
CTGGATTGCGGGCTGATCGCTGACGGATTTCATGTCGATCCCGCCGCCATCGGCATTGCGCTACGCGCCAAGAATGGCCC
GGGCCGGATTTTCCTCGTCACCGACGCCATGTCGACCATCGGCACGGATGACGATGGTTTCGAACTGAATGGCCGGCGCG
TCTATCGCAATGGCGGCCGACTGACACTTGAAGACGGCACGCTTGCTGGGGCGGATATCGACATGCTCTCCTGCGTCCGC
TTCATGTATGAAAAGCTGGAGATGCCGCTGGAGGAAGCCTTGAGAATGGCATCCGCCTATCCTGCACAGGCCGTTGGCGC
ATCGGACAAGGGAAAACTGCTGCCCGGCTTCGATGCCGATTTTGTTGTGCTGACGCCCGGCCTCCAGATGCATTCGACCT
GGATTGGCGGAGAAAAAACCTACGATGCCGTGCATTCCGGAGTGTGA

Upstream 100 bases:

>100_bases
TGCTGATTGCGCCGTTTTACGGCTTTATCGAACAATTATCCCGCGCACGCGGCTTCAACCCGGATGCACCCGTGGCATTG
AAGAAGGTAACGGAAACCCA

Downstream 100 bases:

>100_bases
ACCATGATCGTTTGTTTCGATATTGGCGGAACGACCATCAAGGGCGCGATTGCCCATACCCCGGACGACATTCGCCCCGT
GCCACGCATACCAACGCCGA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSGIKAFVGARIFDGAAWHEGRVLVVGDGHVTAISDSVPAEAEMIDVKGLLIAPGFIDLQVNGGGGVMFNNQPDVEGIAR
ICSAHARFGTTALMVTLITDRPDVISKAAQAGIAASKKQVPGFLGLHFEGPHLSVARKGTHDPALVRKMETADLAVLIGC
KAELAFVMTTIAPENVTEEQVAALRKAGIVVSLGHTDTGLDVATAYIEAGASMVTHLFNAMSPLGHREPGLVGAALSNGG
LDCGLIADGFHVDPAAIGIALRAKNGPGRIFLVTDAMSTIGTDDDGFELNGRRVYRNGGRLTLEDGTLAGADIDMLSCVR
FMYEKLEMPLEEALRMASAYPAQAVGASDKGKLLPGFDADFVVLTPGLQMHSTWIGGEKTYDAVHSGV

Sequences:

>Translated_388_residues
MSGIKAFVGARIFDGAAWHEGRVLVVGDGHVTAISDSVPAEAEMIDVKGLLIAPGFIDLQVNGGGGVMFNNQPDVEGIAR
ICSAHARFGTTALMVTLITDRPDVISKAAQAGIAASKKQVPGFLGLHFEGPHLSVARKGTHDPALVRKMETADLAVLIGC
KAELAFVMTTIAPENVTEEQVAALRKAGIVVSLGHTDTGLDVATAYIEAGASMVTHLFNAMSPLGHREPGLVGAALSNGG
LDCGLIADGFHVDPAAIGIALRAKNGPGRIFLVTDAMSTIGTDDDGFELNGRRVYRNGGRLTLEDGTLAGADIDMLSCVR
FMYEKLEMPLEEALRMASAYPAQAVGASDKGKLLPGFDADFVVLTPGLQMHSTWIGGEKTYDAVHSGV
>Mature_387_residues
SGIKAFVGARIFDGAAWHEGRVLVVGDGHVTAISDSVPAEAEMIDVKGLLIAPGFIDLQVNGGGGVMFNNQPDVEGIARI
CSAHARFGTTALMVTLITDRPDVISKAAQAGIAASKKQVPGFLGLHFEGPHLSVARKGTHDPALVRKMETADLAVLIGCK
AELAFVMTTIAPENVTEEQVAALRKAGIVVSLGHTDTGLDVATAYIEAGASMVTHLFNAMSPLGHREPGLVGAALSNGGL
DCGLIADGFHVDPAAIGIALRAKNGPGRIFLVTDAMSTIGTDDDGFELNGRRVYRNGGRLTLEDGTLAGADIDMLSCVRF
MYEKLEMPLEEALRMASAYPAQAVGASDKGKLLPGFDADFVVLTPGLQMHSTWIGGEKTYDAVHSGV

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=383, Percent_Identity=35.7702349869452, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI224922791, Length=377, Percent_Identity=35.8090185676393, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1786892, Length=380, Percent_Identity=36.8421052631579, Blast_Score=231, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17553768, Length=385, Percent_Identity=32.2077922077922, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI19920392, Length=344, Percent_Identity=35.4651162790698, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281361140, Length=357, Percent_Identity=34.453781512605, Blast_Score=170, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40514; Mature: 40383

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIKAFVGARIFDGAAWHEGRVLVVGDGHVTAISDSVPAEAEMIDVKGLLIAPGFIDLQ
CCCHHHHHHHHEECCCCCCCCEEEEEECCEEEEECCCCCCCEEEEEECEEEEECCEEEEE
VNGGGGVMFNNQPDVEGIARICSAHARFGTTALMVTLITDRPDVISKAAQAGIAASKKQV
EECCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHCC
PGFLGLHFEGPHLSVARKGTHDPALVRKMETADLAVLIGCKAELAFVMTTIAPENVTEEQ
CCEEEEEECCCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCCHHH
VAALRKAGIVVSLGHTDTGLDVATAYIEAGASMVTHLFNAMSPLGHREPGLVGAALSNGG
HHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
LDCGLIADGFHVDPAAIGIALRAKNGPGRIFLVTDAMSTIGTDDDGFELNGRRVYRNGGR
CEEEEEECCCEECHHHEEEEEEECCCCCEEEEEECCHHHCCCCCCCEEECCEEEEECCCE
LTLEDGTLAGADIDMLSCVRFMYEKLEMPLEEALRMASAYPAQAVGASDKGKLLPGFDAD
EEEECCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCC
FVVLTPGLQMHSTWIGGEKTYDAVHSGV
EEEECCCCEEEEEECCCCHHHHHHHCCC
>Mature Secondary Structure 
SGIKAFVGARIFDGAAWHEGRVLVVGDGHVTAISDSVPAEAEMIDVKGLLIAPGFIDLQ
CCHHHHHHHHEECCCCCCCCEEEEEECCEEEEECCCCCCCEEEEEECEEEEECCEEEEE
VNGGGGVMFNNQPDVEGIARICSAHARFGTTALMVTLITDRPDVISKAAQAGIAASKKQV
EECCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHCC
PGFLGLHFEGPHLSVARKGTHDPALVRKMETADLAVLIGCKAELAFVMTTIAPENVTEEQ
CCEEEEEECCCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCCHHH
VAALRKAGIVVSLGHTDTGLDVATAYIEAGASMVTHLFNAMSPLGHREPGLVGAALSNGG
HHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
LDCGLIADGFHVDPAAIGIALRAKNGPGRIFLVTDAMSTIGTDDDGFELNGRRVYRNGGR
CEEEEEECCCEECHHHEEEEEEECCCCCEEEEEECCHHHCCCCCCCEEECCEEEEECCCE
LTLEDGTLAGADIDMLSCVRFMYEKLEMPLEEALRMASAYPAQAVGASDKGKLLPGFDAD
EEEECCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCC
FVVLTPGLQMHSTWIGGEKTYDAVHSGV
EEEECCCCEEEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]