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The map label for this gene is rssA [H]

Identifier: 15889736

GI number: 15889736

Start: 2434187

End: 2435581

Strand: Reverse

Name: rssA [H]

Synonym: Atu2465

Alternate gene names: 15889736

Gene position: 2435581-2434187 (Counterclockwise)

Preceding gene: 159185227

Following gene: 159185225

Centisome position: 85.71

GC content: 64.37

Gene sequence:

>1395_bases
ATGAGACAGGCCGCCTATTCGCTCAGGCGGCGACTGTTAGGCTGGCTTCTCATCTCCACAGCTATCATTGGCTGCGTTGC
GCTGACCGACACCTGGCGCGAGGCGGTCAACACCGCCAATGTGGTGTCCGACCGGGTGCTATCAGGCTCCGCACTTGCCA
TTGCCGAGCGGGTGGTGGTGGCCGAGGACGGTTCGCTGGAAGTCGATATTCCCTATGTCGCGCTGGAAATGCTGACATCT
GCAGCGCAGGACCGGGTGTTTTACCGGGTCGATGGGCCGAACGGGCAATTCCTCACCGGTTACCAGACCCTGCCGACGGT
GGAGAACACCAATGGTGATACGCCTGCCTACCGGGACGCCGTCTTCCGCGACGAGCCGATCCGCATCGCCGCTATCAGGC
GTTTTGCCTCCACGGGCATCAATTCCGTGCCGTTTTCCGTGACCGTTGCCGAAACCACGATTGCTCGCAGCCAGCTGGCG
CAGGCGATCATCCTGCGCTCCGCGCTGCGCCTGCTGTTGATGATCGTGGGCGCGGCGATCATCGTCTGGATCGCGGTGAC
GATTTCGCTCAGGCCGCTTTACCGGCTCAGCGAAGCCATTGCCGAGCGCAGCCCGAACGATCTGCACCCCATCCGCCAAT
CCGTGCCGGTGGAGGTGGAAAATCTGGTGGAAACCGTCAATTCGTTCATGGTGCGGCTGCAATCGGCGCTTGATGCGCTC
CGGCATTTCACCGGCAATGCCAGCCACCAGCTGCGCACGCCGCTCGCCATTATCAGCACCCAGCTTGCGCTTTCCGCCCG
CGCCGCAAGCCTTGAGGAGGCGCAGGCGGCGGCGCTGAAGGGCGGCGCTTCGGTGGCTCATGCCGAACATATCCTCGCCC
AGCTCCTGCGCATGGCCAATATCGATGCCGCCGGCTCCAGCGAGAAACACGATTTTTCCGCCATCGACCTCGTGGCGGTG
GCTCAGAATGTGACGGCCGATTTTGTGCCGCGCGCAGCCGACGCCGGTATCGATCTCGGTTTCGAAGGCGAGGGCGAGGC
GACCATTTCCGCCGAGCCGCTCTTGATCGGCGAGTTGATCGGCAATCTCGTTTCCAATGCCATCAATTATGCCGGGCGCG
GGGCGGAAGTTACCGTCCGCGTCGGCGGGCCAGCGGGTGCGGTATGGCTGGAAGTGGAGGATAACGGCCCCGGCATCCCC
CCGGAAAAACGCGCCATGGTGCGCCAGCGTTTCGCCCGCGGCGAAGCCAATGCCGCCCCCGGTGCCGGCCTCGGCCTTGC
CATTATCGAGGAAATCGCCGGCCTGTTTGGCGGGCGGTTGACGCTGGAAGACGGCGCGGACGGGCGCGGATTGAAGGCGC
GGGTGGTGTTCGCCGCGCCGGAAAGAGCGGCATAG

Upstream 100 bases:

>100_bases
ATGTCAGCCGCCTGCGCAAGCGGCTCGCTCCCCACGGGCTGACGGTGAAGACGGCGCGCGGCATCGGTTATTATCTGGAA
AAGCTGCCGGAGATGGCTGA

Downstream 100 bases:

>100_bases
CAGGGCGGCCTATCAGGCAGCCTTGTCTGCTGCCACCTTATCACCCCATCCGCTCGGAAGCATAGCTGCCGGGGCTCGGC
GGGAAGACCACGGTGCGGTT

Product: two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MRQAAYSLRRRLLGWLLISTAIIGCVALTDTWREAVNTANVVSDRVLSGSALAIAERVVVAEDGSLEVDIPYVALEMLTS
AAQDRVFYRVDGPNGQFLTGYQTLPTVENTNGDTPAYRDAVFRDEPIRIAAIRRFASTGINSVPFSVTVAETTIARSQLA
QAIILRSALRLLLMIVGAAIIVWIAVTISLRPLYRLSEAIAERSPNDLHPIRQSVPVEVENLVETVNSFMVRLQSALDAL
RHFTGNASHQLRTPLAIISTQLALSARAASLEEAQAAALKGGASVAHAEHILAQLLRMANIDAAGSSEKHDFSAIDLVAV
AQNVTADFVPRAADAGIDLGFEGEGEATISAEPLLIGELIGNLVSNAINYAGRGAEVTVRVGGPAGAVWLEVEDNGPGIP
PEKRAMVRQRFARGEANAAPGAGLGLAIIEEIAGLFGGRLTLEDGADGRGLKARVVFAAPERAA

Sequences:

>Translated_464_residues
MRQAAYSLRRRLLGWLLISTAIIGCVALTDTWREAVNTANVVSDRVLSGSALAIAERVVVAEDGSLEVDIPYVALEMLTS
AAQDRVFYRVDGPNGQFLTGYQTLPTVENTNGDTPAYRDAVFRDEPIRIAAIRRFASTGINSVPFSVTVAETTIARSQLA
QAIILRSALRLLLMIVGAAIIVWIAVTISLRPLYRLSEAIAERSPNDLHPIRQSVPVEVENLVETVNSFMVRLQSALDAL
RHFTGNASHQLRTPLAIISTQLALSARAASLEEAQAAALKGGASVAHAEHILAQLLRMANIDAAGSSEKHDFSAIDLVAV
AQNVTADFVPRAADAGIDLGFEGEGEATISAEPLLIGELIGNLVSNAINYAGRGAEVTVRVGGPAGAVWLEVEDNGPGIP
PEKRAMVRQRFARGEANAAPGAGLGLAIIEEIAGLFGGRLTLEDGADGRGLKARVVFAAPERAA
>Mature_464_residues
MRQAAYSLRRRLLGWLLISTAIIGCVALTDTWREAVNTANVVSDRVLSGSALAIAERVVVAEDGSLEVDIPYVALEMLTS
AAQDRVFYRVDGPNGQFLTGYQTLPTVENTNGDTPAYRDAVFRDEPIRIAAIRRFASTGINSVPFSVTVAETTIARSQLA
QAIILRSALRLLLMIVGAAIIVWIAVTISLRPLYRLSEAIAERSPNDLHPIRQSVPVEVENLVETVNSFMVRLQSALDAL
RHFTGNASHQLRTPLAIISTQLALSARAASLEEAQAAALKGGASVAHAEHILAQLLRMANIDAAGSSEKHDFSAIDLVAV
AQNVTADFVPRAADAGIDLGFEGEGEATISAEPLLIGELIGNLVSNAINYAGRGAEVTVRVGGPAGAVWLEVEDNGPGIP
PEKRAMVRQRFARGEANAAPGAGLGLAIIEEIAGLFGGRLTLEDGADGRGLKARVVFAAPERAA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=316, Percent_Identity=28.7974683544304, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790551, Length=296, Percent_Identity=28.0405405405405, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=28.2758620689655, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789808, Length=302, Percent_Identity=29.1390728476821, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787374, Length=282, Percent_Identity=24.468085106383, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790861, Length=297, Percent_Identity=26.2626262626263, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=32.618025751073, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=29.6610169491525, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788279, Length=305, Percent_Identity=24.2622950819672, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=25.5506607929515, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=29.1479820627803, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=247, Percent_Identity=26.7206477732794, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49157; Mature: 49157

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQAAYSLRRRLLGWLLISTAIIGCVALTDTWREAVNTANVVSDRVLSGSALAIAERVVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEE
AEDGSLEVDIPYVALEMLTSAAQDRVFYRVDGPNGQFLTGYQTLPTVENTNGDTPAYRDA
ECCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCHHHHH
VFRDEPIRIAAIRRFASTGINSVPFSVTVAETTIARSQLAQAIILRSALRLLLMIVGAAI
HCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWIAVTISLRPLYRLSEAIAERSPNDLHPIRQSVPVEVENLVETVNSFMVRLQSALDAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RHFTGNASHQLRTPLAIISTQLALSARAASLEEAQAAALKGGASVAHAEHILAQLLRMAN
HHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
IDAAGSSEKHDFSAIDLVAVAQNVTADFVPRAADAGIDLGFEGEGEATISAEPLLIGELI
CCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
GNLVSNAINYAGRGAEVTVRVGGPAGAVWLEVEDNGPGIPPEKRAMVRQRFARGEANAAP
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GAGLGLAIIEEIAGLFGGRLTLEDGADGRGLKARVVFAAPERAA
CCCHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MRQAAYSLRRRLLGWLLISTAIIGCVALTDTWREAVNTANVVSDRVLSGSALAIAERVVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEE
AEDGSLEVDIPYVALEMLTSAAQDRVFYRVDGPNGQFLTGYQTLPTVENTNGDTPAYRDA
ECCCCEEEEHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCHHHHH
VFRDEPIRIAAIRRFASTGINSVPFSVTVAETTIARSQLAQAIILRSALRLLLMIVGAAI
HCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWIAVTISLRPLYRLSEAIAERSPNDLHPIRQSVPVEVENLVETVNSFMVRLQSALDAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RHFTGNASHQLRTPLAIISTQLALSARAASLEEAQAAALKGGASVAHAEHILAQLLRMAN
HHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
IDAAGSSEKHDFSAIDLVAVAQNVTADFVPRAADAGIDLGFEGEGEATISAEPLLIGELI
CCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHH
GNLVSNAINYAGRGAEVTVRVGGPAGAVWLEVEDNGPGIPPEKRAMVRQRFARGEANAAP
HHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
GAGLGLAIIEEIAGLFGGRLTLEDGADGRGLKARVVFAAPERAA
CCCHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA