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The map label for this gene is occM [H]

Identifier: 15889637

GI number: 15889637

Start: 2338450

End: 2339139

Strand: Reverse

Name: occM [H]

Synonym: Atu2363

Alternate gene names: 15889637

Gene position: 2339139-2338450 (Counterclockwise)

Preceding gene: 15889638

Following gene: 159185173

Centisome position: 82.32

GC content: 62.17

Gene sequence:

>690_bases
ATGGATTTTTCATGGGTCGCCAAATATTGGCCGCTGCTTCTGTCCGGCGCCTGGCAGACGCTGGCGCTGCTCGTCATCTC
CGTCAGCATCGGTTTCGTGCTGGCTATCGGGCTTGCCTTCGCGCAGGTCAGCGGCGGACGGGTGACGAAAATTCTGGCGC
GCGCCTATTGCACCTTCTTCCGCGGCACGCCGCTTTTGATCCAGCTCTGGCTGCTTTATTATGGCGTCGGTTCGTTTCTG
CCGATGATCCCTGGCCTGCGCCAGAGTTTCATGTGGCCGGTGCTGCGCGAGGGCTTTTTCTTCGCCGCCGTCAGCTTCAC
GCTGAATTACGCGGCCTATGAGGCCGAGGTGCTGCGCGGTGCGCTGCTGGCCGTGCCGAAGGGCGAGCTGGAGGCGGGCC
GGGCTTTCGGCATGGGCCGCTTCACCCTCATTCGCCGCATCTGGTTACCGCGCGCGATCCGCATCGCGCTGCCGACCATA
ACCGGGGAGGTGGTGATGCAGCTCAAAGCGACGCCGCTTGCTTTTACGGTCACTGTGATGGACCTCTACGCCGTCGCCTA
CAAGGTGCGGCAGGATACGCTGCTGGTCTATGAGCCGCTGATCGTCGTTACCGTCTTTTATCTCATTCTCACCGCCATCA
TTGCCCGCTGTTTCGGCCTTGTCGAACGGCAGGTGCCGGTCCGGCGGTAA

Upstream 100 bases:

>100_bases
TTCTTTATCTCGCGATCACGCTCGTCTCCAACCTCGTCTTTTCACAGCTGGAACGCCGGGTGCGGCGCGGCCAGCCGGCT
TTGGCCTGAGGGGGAACGGC

Downstream 100 bases:

>100_bases
AACCGTTCAAGGAGTATGAACATGGGCACTATCCGTATCCTCGACGGCGGCATGAGCCGCGAATTGCAGCGGCTCGGCGC
CGAGCTGAAACAGCCGGAAT

Product: ABC transporter, membrane spanning protein

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MDFSWVAKYWPLLLSGAWQTLALLVISVSIGFVLAIGLAFAQVSGGRVTKILARAYCTFFRGTPLLIQLWLLYYGVGSFL
PMIPGLRQSFMWPVLREGFFFAAVSFTLNYAAYEAEVLRGALLAVPKGELEAGRAFGMGRFTLIRRIWLPRAIRIALPTI
TGEVVMQLKATPLAFTVTVMDLYAVAYKVRQDTLLVYEPLIVVTVFYLILTAIIARCFGLVERQVPVRR

Sequences:

>Translated_229_residues
MDFSWVAKYWPLLLSGAWQTLALLVISVSIGFVLAIGLAFAQVSGGRVTKILARAYCTFFRGTPLLIQLWLLYYGVGSFL
PMIPGLRQSFMWPVLREGFFFAAVSFTLNYAAYEAEVLRGALLAVPKGELEAGRAFGMGRFTLIRRIWLPRAIRIALPTI
TGEVVMQLKATPLAFTVTVMDLYAVAYKVRQDTLLVYEPLIVVTVFYLILTAIIARCFGLVERQVPVRR
>Mature_229_residues
MDFSWVAKYWPLLLSGAWQTLALLVISVSIGFVLAIGLAFAQVSGGRVTKILARAYCTFFRGTPLLIQLWLLYYGVGSFL
PMIPGLRQSFMWPVLREGFFFAAVSFTLNYAAYEAEVLRGALLAVPKGELEAGRAFGMGRFTLIRRIWLPRAIRIALPTI
TGEVVMQLKATPLAFTVTVMDLYAVAYKVRQDTLLVYEPLIVVTVFYLILTAIIARCFGLVERQVPVRR

Specific function: Component of the octopine active transport system probably consisting of four subunits:Q, M, P and T [H]

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788645, Length=224, Percent_Identity=37.0535714285714, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788226, Length=218, Percent_Identity=33.4862385321101, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787086, Length=220, Percent_Identity=31.3636363636364, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1787030, Length=230, Percent_Identity=31.7391304347826, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788646, Length=229, Percent_Identity=31.0043668122271, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786874, Length=213, Percent_Identity=27.2300469483568, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787087, Length=210, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786873, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87082239, Length=175, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25652; Mature: 25652

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSWVAKYWPLLLSGAWQTLALLVISVSIGFVLAIGLAFAQVSGGRVTKILARAYCTFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGTPLLIQLWLLYYGVGSFLPMIPGLRQSFMWPVLREGFFFAAVSFTLNYAAYEAEVLRG
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALLAVPKGELEAGRAFGMGRFTLIRRIWLPRAIRIALPTITGEVVMQLKATPLAFTVTVM
HHHCCCCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DLYAVAYKVRQDTLLVYEPLIVVTVFYLILTAIIARCFGLVERQVPVRR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDFSWVAKYWPLLLSGAWQTLALLVISVSIGFVLAIGLAFAQVSGGRVTKILARAYCTFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGTPLLIQLWLLYYGVGSFLPMIPGLRQSFMWPVLREGFFFAAVSFTLNYAAYEAEVLRG
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALLAVPKGELEAGRAFGMGRFTLIRRIWLPRAIRIALPTITGEVVMQLKATPLAFTVTVM
HHHCCCCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DLYAVAYKVRQDTLLVYEPLIVVTVFYLILTAIIARCFGLVERQVPVRR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1655707; 1732218 [H]