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The map label for this gene is engA

Identifier: 15889576

GI number: 15889576

Start: 2274968

End: 2276398

Strand: Reverse

Name: engA

Synonym: Atu2300

Alternate gene names: 15889576

Gene position: 2276398-2274968 (Counterclockwise)

Preceding gene: 159185150

Following gene: 15889575

Centisome position: 80.11

GC content: 62.4

Gene sequence:

>1431_bases
ATGAGCTTCACCGTCGCCATAGTCGGGCGCCCCAATGTCGGCAAGTCCACGCTTTTCAACCGTCTGGTCGGAAAGAAGCT
GGCGCTGGTGGACGACACACCGGGCGTGACCCGCGACCGCCGCCCCGGCGATGCCAAGCTCATAGACCTGCGCTTCACCA
TCATCGATACCGCCGGTCTGGAGCAATCCGGGCCGGAAACGCTTCAGGGCCGTATGTGGGCGCAGACGGAAGCGGCGATC
GATGAAGCCGATGTGACGTTGTTTGTCATCGACGCCAAGGCCGGACTGACGCCCGCCGACGAGACGCTGGGCGAAATGTT
GCGCCGTCGCGGCAAGCCGGTGGTGCTGGTGGCCAACAAGTCAGAAGCGCGCGGTTCCGATGCCGGTTTTTATGACGCCT
TTACCCTCGGTCTTGGCGAGCCTTGCCCGGTTTCAGCCGAACATGGTCAGGGCATGATCGACCTGCGCGACGCCATTGTC
GAGGCGATCGGCGAAGACATGGCGTTCCCGCCTGATGTGGATGAGGCGGAAACGGATATTGTGCTTCCGCGCACTGAGCC
CGGCAGCGAGGAAGAAGAAGACGAAGAGCCCGTCTATGACGAGACCAAGCCGCTGCGCGTCGCCATCATCGGCCGGCCGA
ATGCGGGCAAGTCGACGCTCATCAACCGTTTCCTCGGCGAAGACCGGCTGCTGACCGGCCCGGAAGCCGGCATTACCCGT
GACAGCATTTCGGTCGAATGGGACTGGCGCGGCCGCACCATCAAGATGTTCGATACGGCCGGCATGCGCCGCAAGGCCAA
GGTGACGGAAAAGCTGGAAAAGCTCTCGGTCGCGGATTCGCTGCGCTCCATCCGTTTTGCGGAAACCGTCGTCATCGTTT
TCGACAGCACCATCCCATTCGAAAAGCAGGATCTGCAGCTGGTCGATCTCGTCATTCGCGAAGGCCGCGCCGCCGTGCTC
GCCTTCAACAAGTGGGATCTCGTGGAAGACCCGCAGGCCTATCTGGCCGATCTGCGCGAAAAGACCGAGCGTCTCTTGCC
GCAGGCGCGTGGCATCCGTGCCGTGCCAATGTCCGGCCAAACGGGTTATGGCCTCGACCGGCTGATGCAGAGCATCATCG
ATACGGACAAGACCTGGAACCGCCGCATCTCGACCGCCAAGCTCAACCGCTGGCTGGATGCGCAGACCACGCAGCATCCG
CCGCCAGCCGTTTCCGGCCGACGCCTGAAGCTGAAATACATGACGCAGGTCAAGGCCCGCCCGCCGGCCTTCATGATTTC
CTGCACCCGTCCGGAAGCCATTCCGGAGAGCTATACGCGTTATCTCGTCAACGGCCTGCGCAAGGATTTCGACATGCCAG
GCGTACCGATCCGCGTGCATTATCGTGGCTCGGACAATCCGTTCGAGAGCAAGGCGAAGAAGCGGCGGTGA

Upstream 100 bases:

>100_bases
TCTTTGCATTGCCAAAGCGATCCAACTCATTATTTTACGCATGTCTTTTGCCCAAAACAGGTAACGTTTTGGGCAGACTT
GCTCTAAGGAACACACAACA

Downstream 100 bases:

>100_bases
TCGGCCTGCGGTTTTGAGGCACGACGATGTGGCATTTTCTTCTCCCCGGCGGGGAGAAGATGGCCCGAAGGGTCAGATGA
GAGGGCAACCTCTCCTTATA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDAKLIDLRFTIIDTAGLEQSGPETLQGRMWAQTEAAI
DEADVTLFVIDAKAGLTPADETLGEMLRRRGKPVVLVANKSEARGSDAGFYDAFTLGLGEPCPVSAEHGQGMIDLRDAIV
EAIGEDMAFPPDVDEAETDIVLPRTEPGSEEEEDEEPVYDETKPLRVAIIGRPNAGKSTLINRFLGEDRLLTGPEAGITR
DSISVEWDWRGRTIKMFDTAGMRRKAKVTEKLEKLSVADSLRSIRFAETVVIVFDSTIPFEKQDLQLVDLVIREGRAAVL
AFNKWDLVEDPQAYLADLREKTERLLPQARGIRAVPMSGQTGYGLDRLMQSIIDTDKTWNRRISTAKLNRWLDAQTTQHP
PPAVSGRRLKLKYMTQVKARPPAFMISCTRPEAIPESYTRYLVNGLRKDFDMPGVPIRVHYRGSDNPFESKAKKRR

Sequences:

>Translated_476_residues
MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDAKLIDLRFTIIDTAGLEQSGPETLQGRMWAQTEAAI
DEADVTLFVIDAKAGLTPADETLGEMLRRRGKPVVLVANKSEARGSDAGFYDAFTLGLGEPCPVSAEHGQGMIDLRDAIV
EAIGEDMAFPPDVDEAETDIVLPRTEPGSEEEEDEEPVYDETKPLRVAIIGRPNAGKSTLINRFLGEDRLLTGPEAGITR
DSISVEWDWRGRTIKMFDTAGMRRKAKVTEKLEKLSVADSLRSIRFAETVVIVFDSTIPFEKQDLQLVDLVIREGRAAVL
AFNKWDLVEDPQAYLADLREKTERLLPQARGIRAVPMSGQTGYGLDRLMQSIIDTDKTWNRRISTAKLNRWLDAQTTQHP
PPAVSGRRLKLKYMTQVKARPPAFMISCTRPEAIPESYTRYLVNGLRKDFDMPGVPIRVHYRGSDNPFESKAKKRR
>Mature_475_residues
SFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDAKLIDLRFTIIDTAGLEQSGPETLQGRMWAQTEAAID
EADVTLFVIDAKAGLTPADETLGEMLRRRGKPVVLVANKSEARGSDAGFYDAFTLGLGEPCPVSAEHGQGMIDLRDAIVE
AIGEDMAFPPDVDEAETDIVLPRTEPGSEEEEDEEPVYDETKPLRVAIIGRPNAGKSTLINRFLGEDRLLTGPEAGITRD
SISVEWDWRGRTIKMFDTAGMRRKAKVTEKLEKLSVADSLRSIRFAETVVIVFDSTIPFEKQDLQLVDLVIREGRAAVLA
FNKWDLVEDPQAYLADLREKTERLLPQARGIRAVPMSGQTGYGLDRLMQSIIDTDKTWNRRISTAKLNRWLDAQTTQHPP
PAVSGRRLKLKYMTQVKARPPAFMISCTRPEAIPESYTRYLVNGLRKDFDMPGVPIRVHYRGSDNPFESKAKKRR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=472, Percent_Identity=41.3135593220339, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1788919, Length=161, Percent_Identity=31.6770186335404, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367268, Length=169, Percent_Identity=33.1360946745562, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_AGRT5 (Q8UD28)

Other databases:

- EMBL:   AE007869
- PIR:   A97636
- PIR:   AC2859
- RefSeq:   NP_355257.1
- ProteinModelPortal:   Q8UD28
- SMR:   Q8UD28
- STRING:   Q8UD28
- GeneID:   1134338
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2300
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q8UD28
- ProtClustDB:   PRK00093
- BioCyc:   ATUM176299-1:ATU2300-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 53048; Mature: 52917

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDAKLIDLRFTIIDTAGL
CCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEEECCC
EQSGPETLQGRMWAQTEAAIDEADVTLFVIDAKAGLTPADETLGEMLRRRGKPVVLVANK
CCCCCHHHCCCCEEHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECC
SEARGSDAGFYDAFTLGLGEPCPVSAEHGQGMIDLRDAIVEAIGEDMAFPPDVDEAETDI
CCCCCCCCCCEEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VLPRTEPGSEEEEDEEPVYDETKPLRVAIIGRPNAGKSTLINRFLGEDRLLTGPEAGITR
EEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCC
DSISVEWDWRGRTIKMFDTAGMRRKAKVTEKLEKLSVADSLRSIRFAETVVIVFDSTIPF
CCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCC
EKQDLQLVDLVIREGRAAVLAFNKWDLVEDPQAYLADLREKTERLLPQARGIRAVPMSGQ
CCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
TGYGLDRLMQSIIDTDKTWNRRISTAKLNRWLDAQTTQHPPPAVSGRRLKLKYMTQVKAR
CCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEHHHCCC
PPAFMISCTRPEAIPESYTRYLVNGLRKDFDMPGVPIRVHYRGSDNPFESKAKKRR
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCCC
>Mature Secondary Structure 
SFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDAKLIDLRFTIIDTAGL
CEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEEECCC
EQSGPETLQGRMWAQTEAAIDEADVTLFVIDAKAGLTPADETLGEMLRRRGKPVVLVANK
CCCCCHHHCCCCEEHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECC
SEARGSDAGFYDAFTLGLGEPCPVSAEHGQGMIDLRDAIVEAIGEDMAFPPDVDEAETDI
CCCCCCCCCCEEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VLPRTEPGSEEEEDEEPVYDETKPLRVAIIGRPNAGKSTLINRFLGEDRLLTGPEAGITR
EEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCC
DSISVEWDWRGRTIKMFDTAGMRRKAKVTEKLEKLSVADSLRSIRFAETVVIVFDSTIPF
CCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCCC
EKQDLQLVDLVIREGRAAVLAFNKWDLVEDPQAYLADLREKTERLLPQARGIRAVPMSGQ
CCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
TGYGLDRLMQSIIDTDKTWNRRISTAKLNRWLDAQTTQHPPPAVSGRRLKLKYMTQVKAR
CCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEHHHCCC
PPAFMISCTRPEAIPESYTRYLVNGLRKDFDMPGVPIRVHYRGSDNPFESKAKKRR
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194