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The map label for this gene is yafC [H]

Identifier: 15889466

GI number: 15889466

Start: 2162154

End: 2163056

Strand: Direct

Name: yafC [H]

Synonym: Atu2186

Alternate gene names: 15889466

Gene position: 2162154-2163056 (Clockwise)

Preceding gene: 159185092

Following gene: 159185093

Centisome position: 76.09

GC content: 58.58

Gene sequence:

>903_bases
ATGGCAATGCCATTGGACTGGGATAAACTGCGCATTTTTCATGCCGCAGCCGAAGCGGGGTCTTTTACCCACGCTGCCGA
CAAGCTGCATTTGTCCCAGTCGGCCATCAGCCGCCAGGTCAGCGCACTGGAACAGGATGTCGGCGTCAAGCTGTTCCACC
GCCATGCCCGCGGCCTGATCCTCACCGAACAGGGCGAGCTGCTGTATCGCACCGCCCATGACGTGCTGCTGAAGCTCGAA
ACGGTGAAGATGCAACTGACCGAAACGACGGAGAAGCCGAGCGGCAAGCTGCGCGTGACGACGACGGTTGGTCTCGGCCA
GGGCTGGCTGACGGACAAGGTGCAGGAATTCCTGCAACTCTATCCGGAAATGTCGATCCAGCTCATCCTCGACAACGAGG
AACTGGACGTGAACATGCGCCATGCCGATTGCGCCATCCGCCTGCGCCAGCCGCAGCAGTCGGACCTTATCCAGCGCAAG
CTGTTCACGGTGCACATGCACGTCTATGCCGCACCGTCATATATCAATCGCCATGGCGAGCCGCAATCGGTCGAAGATCT
CGACAATCACCGCATCATCTCCTTTGGCGAACCCGCGCCTAACTATCTGCTCGACGTTAACTGGCTGGAGAATGCCGGAC
GATCGTCCGACAACACGCGCATTCCGCATCTGCAGATCAACAGCCAGACCTCGATCAAGCGCGCGTGCCTGCTGGGGATT
GGTATTGCCTGTTTGCCCGACTATATCGTCGGTCGCGATCCCGGCCTCATCCAGCTGTCGCTCGCCGCAGATATTCCGTC
CTTCGATACCTATTTCTGCTATCCCGACGAGATGAAAAACGCTGCAAAGCTGAAGGCTTTCCGCGACTTCATCGTCGCCA
AGGCGCGGAACTGGAACTTCTGA

Upstream 100 bases:

>100_bases
CGCCGGCATGGGCTGCATGGCCGCCCTCGAAGCAGAACGCTATCTCACGGCGCAACAACCGCTCGCGGTTGCAGCGGAAT
AACCGAAAGGCAGGATAGGC

Downstream 100 bases:

>100_bases
CGTAAAAATAATCGACGTCGAAAGATAATCTTTAAAATTCAAAGCCTTGTAAAGGTAGAAGCAAGAGGGGCGCGCAGGCG
CCCTTCTTCAGCTTTGCACA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAMPLDWDKLRIFHAAAEAGSFTHAADKLHLSQSAISRQVSALEQDVGVKLFHRHARGLILTEQGELLYRTAHDVLLKLE
TVKMQLTETTEKPSGKLRVTTTVGLGQGWLTDKVQEFLQLYPEMSIQLILDNEELDVNMRHADCAIRLRQPQQSDLIQRK
LFTVHMHVYAAPSYINRHGEPQSVEDLDNHRIISFGEPAPNYLLDVNWLENAGRSSDNTRIPHLQINSQTSIKRACLLGI
GIACLPDYIVGRDPGLIQLSLAADIPSFDTYFCYPDEMKNAAKLKAFRDFIVAKARNWNF

Sequences:

>Translated_300_residues
MAMPLDWDKLRIFHAAAEAGSFTHAADKLHLSQSAISRQVSALEQDVGVKLFHRHARGLILTEQGELLYRTAHDVLLKLE
TVKMQLTETTEKPSGKLRVTTTVGLGQGWLTDKVQEFLQLYPEMSIQLILDNEELDVNMRHADCAIRLRQPQQSDLIQRK
LFTVHMHVYAAPSYINRHGEPQSVEDLDNHRIISFGEPAPNYLLDVNWLENAGRSSDNTRIPHLQINSQTSIKRACLLGI
GIACLPDYIVGRDPGLIQLSLAADIPSFDTYFCYPDEMKNAAKLKAFRDFIVAKARNWNF
>Mature_299_residues
AMPLDWDKLRIFHAAAEAGSFTHAADKLHLSQSAISRQVSALEQDVGVKLFHRHARGLILTEQGELLYRTAHDVLLKLET
VKMQLTETTEKPSGKLRVTTTVGLGQGWLTDKVQEFLQLYPEMSIQLILDNEELDVNMRHADCAIRLRQPQQSDLIQRKL
FTVHMHVYAAPSYINRHGEPQSVEDLDNHRIISFGEPAPNYLLDVNWLENAGRSSDNTRIPHLQINSQTSIKRACLLGIG
IACLPDYIVGRDPGLIQLSLAADIPSFDTYFCYPDEMKNAAKLKAFRDFIVAKARNWNF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=30.976430976431, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=27.6666666666667, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789639, Length=238, Percent_Identity=30.2521008403361, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=29.2682926829268, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=25.8389261744966, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081978, Length=180, Percent_Identity=28.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789440, Length=297, Percent_Identity=23.9057239057239, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789173, Length=309, Percent_Identity=25.5663430420712, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788706, Length=180, Percent_Identity=27.2222222222222, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=34.2857142857143, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790262, Length=253, Percent_Identity=28.0632411067194, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=24.9158249158249, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=175, Percent_Identity=27.4285714285714, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=265, Percent_Identity=24.1509433962264, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367136, Length=291, Percent_Identity=23.0240549828179, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790783, Length=246, Percent_Identity=28.4552845528455, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789204, Length=120, Percent_Identity=32.5, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790399, Length=248, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=129, Percent_Identity=24.031007751938, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33972; Mature: 33841

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMPLDWDKLRIFHAAAEAGSFTHAADKLHLSQSAISRQVSALEQDVGVKLFHRHARGLI
CCCCCCHHHHHEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEE
LTEQGELLYRTAHDVLLKLETVKMQLTETTEKPSGKLRVTTTVGLGQGWLTDKVQEFLQL
EECCCCEEEHHHHHHHEEHHHHEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
YPEMSIQLILDNEELDVNMRHADCAIRLRQPQQSDLIQRKLFTVHMHVYAAPSYINRHGE
CCCCEEEEEEECCCCEEEEEECCEEEEECCCCHHHHHHHHHEEEEEEEEECCHHHHCCCC
PQSVEDLDNHRIISFGEPAPNYLLDVNWLENAGRSSDNTRIPHLQINSQTSIKRACLLGI
CCCHHHCCCCEEEEECCCCCCEEEEEHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
GIACLPDYIVGRDPGLIQLSLAADIPSFDTYFCYPDEMKNAAKLKAFRDFIVAKARNWNF
CHHHHCHHHHCCCCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AMPLDWDKLRIFHAAAEAGSFTHAADKLHLSQSAISRQVSALEQDVGVKLFHRHARGLI
CCCCCHHHHHEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEE
LTEQGELLYRTAHDVLLKLETVKMQLTETTEKPSGKLRVTTTVGLGQGWLTDKVQEFLQL
EECCCCEEEHHHHHHHEEHHHHEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
YPEMSIQLILDNEELDVNMRHADCAIRLRQPQQSDLIQRKLFTVHMHVYAAPSYINRHGE
CCCCEEEEEEECCCCEEEEEECCEEEEECCCCHHHHHHHHHEEEEEEEEECCHHHHCCCC
PQSVEDLDNHRIISFGEPAPNYLLDVNWLENAGRSSDNTRIPHLQINSQTSIKRACLLGI
CCCHHHCCCCEEEEECCCCCCEEEEEHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHC
GIACLPDYIVGRDPGLIQLSLAADIPSFDTYFCYPDEMKNAAKLKAFRDFIVAKARNWNF
CHHHHCHHHHCCCCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]