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The map label for this gene is cfa [H]

Identifier: 15889267

GI number: 15889267

Start: 1941524

End: 1942549

Strand: Reverse

Name: cfa [H]

Synonym: Atu1974

Alternate gene names: 15889267

Gene position: 1942549-1941524 (Counterclockwise)

Preceding gene: 159184999

Following gene: 159184996

Centisome position: 68.36

GC content: 57.6

Gene sequence:

>1026_bases
ATGAACATGCTTGCCTTCGCCATCAATGCCGCAGAACGCGCACCGCTCAACGACGGCGTCACGCTGGCTGGTATAGATAT
GCTCTGCGCACGAACGAAACGGCGGCTTGCAATTATCCCTGCTGATGCGGAATTGGCCTTTGTGAAGGATATGGCGATGT
TTCCCATCGCCAGCCATACCGACGAGGCGAACAGACAACATTACGAGGTCCCCGCGGAATTTTTTTCGCTGGTTCTCGGA
GCGCAGCGCAAATATTCCAGCTGTTATTATCCCGATGACACGACGACGCTCGATGAAGCCGAGACTACGGCGCTCTCCGA
GACTGTGGCCCATGCGGGGCTGCTCGATGGCATGGATATCCTCGAACTCGGCTGTGGGTGGGGCTCGCTCTCGCTCTATA
TGGCAGGCTGTTTTCCCAACGCCCGGATCACGTCGGTTTCGAATTCCGCATCGCAGCGCGACTACATCATCGGCTGCGCC
CGGGAGCGGGGCTTTTCCAACCTTTCGGTGGTGACCGTCGACATGAATGATTTCACGACCGCCAATCGTTTCGATCGTGT
CGTCTCGGTGGAAATGTTCGAGCACATGTCGAACTGGCAGAGCCTGTTTGAGCGCGTCCGCTCCTGGCTGCAGCCGGAAG
GCAGGTTCTTCCTTCACGTCTTCAATCACCGTGACCGATCCTACCGCTTTGACCACAATAATCCGGCCGACTGGATCGCG
CAGCATTTCTTTACCGGCGGCATCATGCCCGCTTTCGATCTGCCTCATCGTTTTGGGGAGATTTTCACCGTGGAACAGGA
TTGGCGATGGTCCGGTCTACATTACCGACGGACAGCTCTTGATTGGCTGGCGAATTTTGACCGGGAGATCGACCGTATCC
GGCCGATCTTGAAGCGCGTTTATGGGAACGACGCGCGACTGTGGGAACGTCGCTGGCGACTCTTCTTCCTCGCAACAGCC
GGACTGTTCGGGCATCAGGGTGGCGAGGTCTGGGGTGTAGGGCACTACCTTCTGGCGCCGACCTGA

Upstream 100 bases:

>100_bases
TTGAAGAGCACATGCTGAAATCGCGCGGAGAGAAATTCCGCGCCCTGCAACGCCGCGTCAACGCCTTCTTTCCGGGGCCG
CGCAAGAACGAGGAAACGCC

Downstream 100 bases:

>100_bases
ACCGTGAAGGGAACGGACGGCTCGCGAACGGGCCGGGTTCCAACCCGCTTCAACCAACCTCGAGAACTGAGTGTATTCGT
TGCTTTTCCGCGTCGAGTTC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNMLAFAINAAERAPLNDGVTLAGIDMLCARTKRRLAIIPADAELAFVKDMAMFPIASHTDEANRQHYEVPAEFFSLVLG
AQRKYSSCYYPDDTTTLDEAETTALSETVAHAGLLDGMDILELGCGWGSLSLYMAGCFPNARITSVSNSASQRDYIIGCA
RERGFSNLSVVTVDMNDFTTANRFDRVVSVEMFEHMSNWQSLFERVRSWLQPEGRFFLHVFNHRDRSYRFDHNNPADWIA
QHFFTGGIMPAFDLPHRFGEIFTVEQDWRWSGLHYRRTALDWLANFDREIDRIRPILKRVYGNDARLWERRWRLFFLATA
GLFGHQGGEVWGVGHYLLAPT

Sequences:

>Translated_341_residues
MNMLAFAINAAERAPLNDGVTLAGIDMLCARTKRRLAIIPADAELAFVKDMAMFPIASHTDEANRQHYEVPAEFFSLVLG
AQRKYSSCYYPDDTTTLDEAETTALSETVAHAGLLDGMDILELGCGWGSLSLYMAGCFPNARITSVSNSASQRDYIIGCA
RERGFSNLSVVTVDMNDFTTANRFDRVVSVEMFEHMSNWQSLFERVRSWLQPEGRFFLHVFNHRDRSYRFDHNNPADWIA
QHFFTGGIMPAFDLPHRFGEIFTVEQDWRWSGLHYRRTALDWLANFDREIDRIRPILKRVYGNDARLWERRWRLFFLATA
GLFGHQGGEVWGVGHYLLAPT
>Mature_341_residues
MNMLAFAINAAERAPLNDGVTLAGIDMLCARTKRRLAIIPADAELAFVKDMAMFPIASHTDEANRQHYEVPAEFFSLVLG
AQRKYSSCYYPDDTTTLDEAETTALSETVAHAGLLDGMDILELGCGWGSLSLYMAGCFPNARITSVSNSASQRDYIIGCA
RERGFSNLSVVTVDMNDFTTANRFDRVVSVEMFEHMSNWQSLFERVRSWLQPEGRFFLHVFNHRDRSYRFDHNNPADWIA
QHFFTGGIMPAFDLPHRFGEIFTVEQDWRWSGLHYRRTALDWLANFDREIDRIRPILKRVYGNDARLWERRWRLFFLATA
GLFGHQGGEVWGVGHYLLAPT

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=272, Percent_Identity=29.0441176470588, Blast_Score=107, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI133904226, Length=274, Percent_Identity=22.992700729927, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 39043; Mature: 39043

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMLAFAINAAERAPLNDGVTLAGIDMLCARTKRRLAIIPADAELAFVKDMAMFPIASHT
CCEEEEEECCHHCCCCCCCCEEHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCC
DEANRQHYEVPAEFFSLVLGAQRKYSSCYYPDDTTTLDEAETTALSETVAHAGLLDGMDI
CCCCCCEEECCHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
LELGCGWGSLSLYMAGCFPNARITSVSNSASQRDYIIGCARERGFSNLSVVTVDMNDFTT
HHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCEEEEEHHHCCCCCEEEEEEECCCCCC
ANRFDRVVSVEMFEHMSNWQSLFERVRSWLQPEGRFFLHVFNHRDRSYRFDHNNPADWIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCCHHHHH
QHFFTGGIMPAFDLPHRFGEIFTVEQDWRWSGLHYRRTALDWLANFDREIDRIRPILKRV
HHHHCCCCCCCCCCCHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGNDARLWERRWRLFFLATAGLFGHQGGEVWGVGHYLLAPT
HCCCHHHHHHHHHEEEEEECCHHCCCCCCEEEECCEEECCC
>Mature Secondary Structure
MNMLAFAINAAERAPLNDGVTLAGIDMLCARTKRRLAIIPADAELAFVKDMAMFPIASHT
CCEEEEEECCHHCCCCCCCCEEHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCC
DEANRQHYEVPAEFFSLVLGAQRKYSSCYYPDDTTTLDEAETTALSETVAHAGLLDGMDI
CCCCCCEEECCHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
LELGCGWGSLSLYMAGCFPNARITSVSNSASQRDYIIGCARERGFSNLSVVTVDMNDFTT
HHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCEEEEEHHHCCCCCEEEEEEECCCCCC
ANRFDRVVSVEMFEHMSNWQSLFERVRSWLQPEGRFFLHVFNHRDRSYRFDHNNPADWIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCCHHHHH
QHFFTGGIMPAFDLPHRFGEIFTVEQDWRWSGLHYRRTALDWLANFDREIDRIRPILKRV
HHHHCCCCCCCCCCCHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGNDARLWERRWRLFFLATAGLFGHQGGEVWGVGHYLLAPT
HCCCHHHHHHHHHEEEEEECCHHCCCCCCEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]