Click here to switch to the map view.

The map label for this gene is purQ [H]

Identifier: 15889146

GI number: 15889146

Start: 1825991

End: 1826614

Strand: Direct

Name: purQ [H]

Synonym: Atu1845

Alternate gene names: 15889146

Gene position: 1825991-1826614 (Clockwise)

Preceding gene: 17935734

Following gene: 15889147

Centisome position: 64.26

GC content: 60.1

Gene sequence:

>624_bases
ATGATCGCGGCGCTGACGAAAATTTCCGGTCAGGCGCCCGTCACCATCTGGCAGACGGAAACGGATATTCCCGATGTCGA
CCTGATCGTCATTCCGGGCGGCTTCTCCTATGGTGACTATCTGCGTTGCGGCGCAATCGCCGCCCGCATGCCGGTCATGC
AGGCCATCCGCGAAAAGGCCGAACAGGGCGTCAAGGTCCTCGGCGTCTGCAACGGCTTCCAGATTCTGGTCGAAGCCGGC
ATGCTGCCGGGTGCGCTGATGCGCAATGCCTCGCTGAAATTCGTCTGCCGTGAAGTGAAGCTCGAAGTCGCCAATAACGA
CACTGAATTCACCCGCGCTTATGACAGGGGCCAGATCCTGCGCTGCCCTGTCGCCCATCACGACGGCAACTATTTCCTCG
ATACGGATGAGCTGAAGTCCGTGGAAGACAACCGTCAGGTCGTGTTCCGTTATGCTGAAGGCACCAACCCCAACGGCTCG
CTGAACGATATTGCCGGCGTCATCAACGCCAAGGGCAATGTTCTCGGCATGATGCCGCATCCGGAAAACCTCATCGAAGC
CGCCCATGGCGGCAATGACGGCCGCGGCCTCTTCGCTTCGGCACTCGGCGTCATCGCAGCCTGA

Upstream 100 bases:

>100_bases
GTCATCGAAAACTACGCCATCAGCATTCTTTAAGCTCCAGGAGCCGCTGCCCATGAAATCCGCTGTCGTCCAACTTCCCG
GCCTCAACCGCGACCGCGAC

Downstream 100 bases:

>100_bases
TGGACCGGGCGGGCTTCAAGCCCGCCTTTTTTGATGCCCGTTCGCGGCTGCCGCTTCGGCCTCTCTTCTGGATGACCTGA
TGTCTCTTGCTTTTCGACTG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIAALTKISGQAPVTIWQTETDIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIREKAEQGVKVLGVCNGFQILVEAG
MLPGALMRNASLKFVCREVKLEVANNDTEFTRAYDRGQILRCPVAHHDGNYFLDTDELKSVEDNRQVVFRYAEGTNPNGS
LNDIAGVINAKGNVLGMMPHPENLIEAAHGGNDGRGLFASALGVIAA

Sequences:

>Translated_207_residues
MIAALTKISGQAPVTIWQTETDIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIREKAEQGVKVLGVCNGFQILVEAG
MLPGALMRNASLKFVCREVKLEVANNDTEFTRAYDRGQILRCPVAHHDGNYFLDTDELKSVEDNRQVVFRYAEGTNPNGS
LNDIAGVINAKGNVLGMMPHPENLIEAAHGGNDGRGLFASALGVIAA
>Mature_207_residues
MIAALTKISGQAPVTIWQTETDIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIREKAEQGVKVLGVCNGFQILVEAG
MLPGALMRNASLKFVCREVKLEVANNDTEFTRAYDRGQILRCPVAHHDGNYFLDTDELKSVEDNRQVVFRYAEGTNPNGS
LNDIAGVINAKGNVLGMMPHPENLIEAAHGGNDGRGLFASALGVIAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=187, Percent_Identity=29.9465240641711, Blast_Score=64, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24582111, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24582109, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17137292, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 22244; Mature: 22244

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAALTKISGQAPVTIWQTETDIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIREKA
CCEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EQGVKVLGVCNGFQILVEAGMLPGALMRNASLKFVCREVKLEVANNDTEFTRAYDRGQIL
HCCCEEEEECCCHHEEHHCCCCCHHHHHCCCHHEEEEEEEEEECCCCCHHHHHCCCCCEE
RCPVAHHDGNYFLDTDELKSVEDNRQVVFRYAEGTNPNGSLNDIAGVINAKGNVLGMMPH
ECCEEECCCCEEEEHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHEECCCCEEEECCC
PENLIEAAHGGNDGRGLFASALGVIAA
CHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIAALTKISGQAPVTIWQTETDIPDVDLIVIPGGFSYGDYLRCGAIAARMPVMQAIREKA
CCEEEEECCCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EQGVKVLGVCNGFQILVEAGMLPGALMRNASLKFVCREVKLEVANNDTEFTRAYDRGQIL
HCCCEEEEECCCHHEEHHCCCCCHHHHHCCCHHEEEEEEEEEECCCCCHHHHHCCCCCEE
RCPVAHHDGNYFLDTDELKSVEDNRQVVFRYAEGTNPNGSLNDIAGVINAKGNVLGMMPH
ECCEEECCCCEEEEHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHEECCCCEEEECCC
PENLIEAAHGGNDGRGLFASALGVIAA
CHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]