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The map label for this gene is sufC [H]

Identifier: 15889126

GI number: 15889126

Start: 1802281

End: 1803036

Strand: Reverse

Name: sufC [H]

Synonym: Atu1823

Alternate gene names: 15889126

Gene position: 1803036-1802281 (Counterclockwise)

Preceding gene: 159184936

Following gene: 159184935

Centisome position: 63.45

GC content: 58.2

Gene sequence:

>756_bases
ATGCTTGAAATCATCGACCTGCACGCAAAGATCGCCGATACCGAAACCGAGATCATCAAGGGCCTCAACCTGAAGGTTGC
CGCTGGTGAAGTCGCCGCCATCATGGGACCGAACGGTTCCGGCAAGTCGACGCTGTCCTACATCCTGTCGGGCCGCGAAG
ATTATGAAGTCACCTCCGGTGATATTCTTTATAACGGCGAAAGCATTCTGGAGCTGGACGCCGCCGAGCGCGCCGCCAAG
GGCATTTTCCTGGCCTTCCAGTACCCGGTCGAAATTCCGGGCGTCGCCACCATGCAGTTCCTGAAGGTTGCGATGAACGA
GCAGCGCAAGGCGCGTGGCGAGTCCGAGTTGACGACGCCGGACTTCATTCGCCGCGTCAAGGAAGCTGCCGGCGACCTGA
AGATCGACATGGAGATGCTGAAGCGTCCGCTGAATGTCGGTTTTTCCGGCGGTGAGAAGAAGCGCGCTGAAATCCTGCAG
ATGGCACTCCTGGAGCCAAAACTCTGCGTTCTCGACGAAACCGATAGCGGCCTCGACATCGATGCGCTGAAGATCGTGGC
AGATGGCGTCAACGCGCTGAAGTCGCCGGATCGTGCCACCGTCGTCATCACCCACTACCAGCGCCTGCTCGATTACATCG
TGCCTGACAGCGTTCATGTTCTTTACAAGGGCAAGATCATCCGCTCGGGCGACAAGGCTCTGGCGCTGGAGCTGGAAAAC
AATGGTTACGCCGACATCATCGGTGAAGCGGCCTAA

Upstream 100 bases:

>100_bases
CATTTCGCTGGAAGGTTCGGTCGGCTAATCCTCACCCAAATACGCACCTGAGTGCGCGACGCTCGCGCACCTTCGCTCAC
ACTGTTCTTAGGATAAATCC

Downstream 100 bases:

>100_bases
GTTTGGCCAGGAGGTGATGTCCATGAACATTCAAACGACCAACCGGCTGACGCCAGCGGAAACCGCGCTGATCGACGCCT
ATACCGCCAAGTTCAGTGAA

Product: ABC transporter, nucleotide binding/ATPase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLEIIDLHAKIADTETEIIKGLNLKVAAGEVAAIMGPNGSGKSTLSYILSGREDYEVTSGDILYNGESILELDAAERAAK
GIFLAFQYPVEIPGVATMQFLKVAMNEQRKARGESELTTPDFIRRVKEAAGDLKIDMEMLKRPLNVGFSGGEKKRAEILQ
MALLEPKLCVLDETDSGLDIDALKIVADGVNALKSPDRATVVITHYQRLLDYIVPDSVHVLYKGKIIRSGDKALALELEN
NGYADIIGEAA

Sequences:

>Translated_251_residues
MLEIIDLHAKIADTETEIIKGLNLKVAAGEVAAIMGPNGSGKSTLSYILSGREDYEVTSGDILYNGESILELDAAERAAK
GIFLAFQYPVEIPGVATMQFLKVAMNEQRKARGESELTTPDFIRRVKEAAGDLKIDMEMLKRPLNVGFSGGEKKRAEILQ
MALLEPKLCVLDETDSGLDIDALKIVADGVNALKSPDRATVVITHYQRLLDYIVPDSVHVLYKGKIIRSGDKALALELEN
NGYADIIGEAA
>Mature_251_residues
MLEIIDLHAKIADTETEIIKGLNLKVAAGEVAAIMGPNGSGKSTLSYILSGREDYEVTSGDILYNGESILELDAAERAAK
GIFLAFQYPVEIPGVATMQFLKVAMNEQRKARGESELTTPDFIRRVKEAAGDLKIDMEMLKRPLNVGFSGGEKKRAEILQ
MALLEPKLCVLDETDSGLDIDALKIVADGVNALKSPDRATVVITHYQRLLDYIVPDSVHVLYKGKIIRSGDKALALELEN
NGYADIIGEAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI255708477, Length=222, Percent_Identity=30.6306306306306, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI42741659, Length=213, Percent_Identity=29.1079812206573, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787972, Length=244, Percent_Identity=57.7868852459016, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI87082267, Length=171, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787370, Length=234, Percent_Identity=26.4957264957265, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789864, Length=220, Percent_Identity=25, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789672, Length=215, Percent_Identity=26.5116279069767, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=221, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081834, Length=197, Percent_Identity=27.9187817258883, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787758, Length=236, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790525, Length=190, Percent_Identity=29.4736842105263, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787029, Length=192, Percent_Identity=27.0833333333333, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994883, Length=241, Percent_Identity=27.3858921161826, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790467, Length=218, Percent_Identity=27.5229357798165, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=241, Percent_Identity=29.045643153527, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=235, Percent_Identity=29.3617021276596, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=213, Percent_Identity=28.6384976525822, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=225, Percent_Identity=30.6666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533592, Length=222, Percent_Identity=28.3783783783784, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=233, Percent_Identity=26.6094420600858, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=234, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=216, Percent_Identity=27.3148148148148, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI85726357, Length=234, Percent_Identity=26.0683760683761, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27291; Mature: 27291

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIIDLHAKIADTETEIIKGLNLKVAAGEVAAIMGPNGSGKSTLSYILSGREDYEVTSG
CCEEEEECCHHCCCHHHHHCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEECCC
DILYNGESILELDAAERAAKGIFLAFQYPVEIPGVATMQFLKVAMNEQRKARGESELTTP
CEEECCCCEEEECHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
DFIRRVKEAAGDLKIDMEMLKRPLNVGFSGGEKKRAEILQMALLEPKLCVLDETDSGLDI
HHHHHHHHHHCCEEEEHHHHHCHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVADGVNALKSPDRATVVITHYQRLLDYIVPDSVHVLYKGKIIRSGDKALALELEN
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECEEEECCCCEEEEEECC
NGYADIIGEAA
CCCEEECCCCC
>Mature Secondary Structure
MLEIIDLHAKIADTETEIIKGLNLKVAAGEVAAIMGPNGSGKSTLSYILSGREDYEVTSG
CCEEEEECCHHCCCHHHHHCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEECCC
DILYNGESILELDAAERAAKGIFLAFQYPVEIPGVATMQFLKVAMNEQRKARGESELTTP
CEEECCCCEEEECHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
DFIRRVKEAAGDLKIDMEMLKRPLNVGFSGGEKKRAEILQMALLEPKLCVLDETDSGLDI
HHHHHHHHHHCCEEEEHHHHHCHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVADGVNALKSPDRATVVITHYQRLLDYIVPDSVHVLYKGKIIRSGDKALALELEN
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECEEEECCCCEEEEEECC
NGYADIIGEAA
CCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]