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The map label for this gene is moaC

Identifier: 15888994

GI number: 15888994

Start: 1673496

End: 1673987

Strand: Direct

Name: moaC

Synonym: Atu1689

Alternate gene names: 15888994

Gene position: 1673496-1673987 (Clockwise)

Preceding gene: 159184873

Following gene: 15888995

Centisome position: 58.89

GC content: 62.4

Gene sequence:

>492_bases
ATGAGCGATGGCCAGAAGCTCACCCATATCGATGCGAGCGGCGAGGCGCATATGGTCGATGTCGGCGACAAGGCCGAGAC
CGTCCGTGTCGCCGTAGCCGAGGGTTTCGTGAAGATGAAGCCGGAAACGCTGGCGCTCATCCGCGACGGCAACGCCAAGA
AGGGCGATGTCATCGGCACCGCGCGCCTCGCCGGCATCATGGCCGCCAAGCAGACGGCAAACCTCATCCCGCTCTGCCAC
CCGCTGATGCTGACCAAGGTAGCCGTGGACATTACCGAGGACACCGGCCTGCCCGGCCTCCGCGTCGAGGCCATGGTGAA
ACTGTCTGGCAAGACCGGCGTGGAAATGGAAGCGCTGACCGCCGTCTCCATCGCCTGCCTGACGATCTATGACATGGCCA
AAGCCGCCGACAAAGGCATGGAAATCGTCAATATCCGTCTTCTCGAAAAGAGCGGCGGCAAATCCGGTGATTTCCGCCGC
CAGGAGAGCTGA

Upstream 100 bases:

>100_bases
CTCGTCGGCGAAAGCCTGATGCGCAAGGACGATGTGACGGCGGCGACCAAGGCCCTGCTGACCGGCCACTCCGGCATTCT
GGCCGCGGAATAATACGCCG

Downstream 100 bases:

>100_bases
ATGAACCCGTTGCTGCCCGTGGACGAGGCCATTAAACGCCTTCTGGAAGCTGCAGTTCCGGTCACGGACAGCGAAACCCT
GCCGCTTGCCGAATGTGATG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MSDGQKLTHIDASGEAHMVDVGDKAETVRVAVAEGFVKMKPETLALIRDGNAKKGDVIGTARLAGIMAAKQTANLIPLCH
PLMLTKVAVDITEDTGLPGLRVEAMVKLSGKTGVEMEALTAVSIACLTIYDMAKAADKGMEIVNIRLLEKSGGKSGDFRR
QES

Sequences:

>Translated_163_residues
MSDGQKLTHIDASGEAHMVDVGDKAETVRVAVAEGFVKMKPETLALIRDGNAKKGDVIGTARLAGIMAAKQTANLIPLCH
PLMLTKVAVDITEDTGLPGLRVEAMVKLSGKTGVEMEALTAVSIACLTIYDMAKAADKGMEIVNIRLLEKSGGKSGDFRR
QES
>Mature_162_residues
SDGQKLTHIDASGEAHMVDVGDKAETVRVAVAEGFVKMKPETLALIRDGNAKKGDVIGTARLAGIMAAKQTANLIPLCHP
LMLTKVAVDITEDTGLPGLRVEAMVKLSGKTGVEMEALTAVSIACLTIYDMAKAADKGMEIVNIRLLEKSGGKSGDFRRQ
ES

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=64.2857142857143, Blast_Score=196, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=47.6510067114094, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=53.5031847133758, Blast_Score=156, Evalue=5e-39,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=53.7931034482759, Blast_Score=143, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_AGRT5 (Q8UER6)

Other databases:

- EMBL:   AE007869
- PIR:   AC2784
- PIR:   C97563
- RefSeq:   NP_354675.1
- ProteinModelPortal:   Q8UER6
- SMR:   Q8UER6
- STRING:   Q8UER6
- GeneID:   1133727
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1689
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   Q8UER6
- ProtClustDB:   PRK09364
- BioCyc:   ATUM176299-1:ATU1689-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17236; Mature: 17105

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: ACT_SITE 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGQKLTHIDASGEAHMVDVGDKAETVRVAVAEGFVKMKPETLALIRDGNAKKGDVIGT
CCCCCEEEEEECCCCEEEEECCCCCCEEEEEEECCEEEECCCEEEEEECCCCCCCCEEEH
ARLAGIMAAKQTANLIPLCHPLMLTKVAVDITEDTGLPGLRVEAMVKLSGKTGVEMEALT
HHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHH
AVSIACLTIYDMAKAADKGMEIVNIRLLEKSGGKSGDFRRQES
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SDGQKLTHIDASGEAHMVDVGDKAETVRVAVAEGFVKMKPETLALIRDGNAKKGDVIGT
CCCCEEEEEECCCCEEEEECCCCCCEEEEEEECCEEEECCCEEEEEECCCCCCCCEEEH
ARLAGIMAAKQTANLIPLCHPLMLTKVAVDITEDTGLPGLRVEAMVKLSGKTGVEMEALT
HHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHH
AVSIACLTIYDMAKAADKGMEIVNIRLLEKSGGKSGDFRRQES
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194