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The map label for this gene is trpD

Identifier: 15888992

GI number: 15888992

Start: 1671634

End: 1672662

Strand: Direct

Name: trpD

Synonym: Atu1687

Alternate gene names: 15888992

Gene position: 1671634-1672662 (Clockwise)

Preceding gene: 15888991

Following gene: 159184873

Centisome position: 58.83

GC content: 64.53

Gene sequence:

>1029_bases
ATGGCCGAACTGAAGCCGCTGATCGCCAAGGTCGCGAACGGAGAAAGCCTGAACCGCGAGGATGCGCGCACGGCTTTCGA
TATTCTGATGTCGGGCGAAGCCACCCCGTCGCAGATCGGCGGTTTCCTGATGGCGCTGCGTGTGCGCGGCGAAACGGTCG
ACGAAATCGTCGGCGCGGTTTCTTCCATGCGTGCCCGCATGCTGCCGGTTTCGGCCCCCGCCAATGCCATCGATATCGTC
GGAACCGGCGGTGATGGCATCGGCACCTACAATATCTCGACGCTGGCCTCGATCATCACAGCCGGCACGGGCCTGCCGGT
CGCCAAGCACGGCAACCGGGCGCTGAGCTCTAAATCCGGCACGGCGGATGCGCTCTCCGCGCTCGGCGTGAGGCTCGATA
TCGGCCCCGATCTCATCGCCCGCTGCATCGCTGAGGCTGGCCTCGGTTTCATGTTCGCGCAGATGCACCATTCCGCCATG
CGCCATGTCGGCCCGAGCCGCGTCGAACTTGGCACCCGGACCATCTTCAACCTGCTCGGCCCGCTCTCCAACCCGGCCGG
CGCAAAACGACAATTGCTCGGCGTCTTTTCGCCACGCTGGCTGGTGCCGCTTGCCGAAGTGCTGCGGGATTTGGGTTCCG
AGAGCATCTGGGTCGTCCACGGCGACGGCATGGATGAAGTCACCACCACGGGCGTCACCCATGTGGCCGCACTGGAAGAC
GGCAAGATCCGCACCTTCGATCTGACACCGAAAGATTTCGGTGTCGAGCCGGCCCTGATGAACGATCTCAAGGGCGGCGA
TGGCATCGCCAATGCAGCGGCGCTGCGCGAGGTTCTCTCCGGCAAGCGCAACGCCTATCGCGACATATCGCTGTGCAACG
CGGCTGCCGCGCTGGTCATTGCTGGCAAGGCGGAGACGCTGAGCCAGGCGATGACGATTGCCAGCGATGCGCTCGACAGC
GGCAAGGCCGCCGCGGCGCTCGACCGTCTGGTCGCCGTATCCAACGAAGCCAATTCAGGGCAGGAATGA

Upstream 100 bases:

>100_bases
TGGATCAGATGGTCAACCGTCTGCAGAATGATTATGGTGTGACGATCAACCAGGCCCTCGCCGATCAGGCGATGGTCGGT
TTCTAACCGGGGGGCGAGAC

Downstream 100 bases:

>100_bases
GAGCGAGACCATGAGCGACATTCTCAAAAAGATCGAGACCTACAAGCTGGAGGAAATCGCCGCCGCCAAGGCCAAGGTTT
CGCTGGCCGATCTGAAGGCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAELKPLIAKVANGESLNREDARTAFDILMSGEATPSQIGGFLMALRVRGETVDEIVGAVSSMRARMLPVSAPANAIDIV
GTGGDGIGTYNISTLASIITAGTGLPVAKHGNRALSSKSGTADALSALGVRLDIGPDLIARCIAEAGLGFMFAQMHHSAM
RHVGPSRVELGTRTIFNLLGPLSNPAGAKRQLLGVFSPRWLVPLAEVLRDLGSESIWVVHGDGMDEVTTTGVTHVAALED
GKIRTFDLTPKDFGVEPALMNDLKGGDGIANAAALREVLSGKRNAYRDISLCNAAAALVIAGKAETLSQAMTIASDALDS
GKAAAALDRLVAVSNEANSGQE

Sequences:

>Translated_342_residues
MAELKPLIAKVANGESLNREDARTAFDILMSGEATPSQIGGFLMALRVRGETVDEIVGAVSSMRARMLPVSAPANAIDIV
GTGGDGIGTYNISTLASIITAGTGLPVAKHGNRALSSKSGTADALSALGVRLDIGPDLIARCIAEAGLGFMFAQMHHSAM
RHVGPSRVELGTRTIFNLLGPLSNPAGAKRQLLGVFSPRWLVPLAEVLRDLGSESIWVVHGDGMDEVTTTGVTHVAALED
GKIRTFDLTPKDFGVEPALMNDLKGGDGIANAAALREVLSGKRNAYRDISLCNAAAALVIAGKAETLSQAMTIASDALDS
GKAAAALDRLVAVSNEANSGQE
>Mature_341_residues
AELKPLIAKVANGESLNREDARTAFDILMSGEATPSQIGGFLMALRVRGETVDEIVGAVSSMRARMLPVSAPANAIDIVG
TGGDGIGTYNISTLASIITAGTGLPVAKHGNRALSSKSGTADALSALGVRLDIGPDLIARCIAEAGLGFMFAQMHHSAMR
HVGPSRVELGTRTIFNLLGPLSNPAGAKRQLLGVFSPRWLVPLAEVLRDLGSESIWVVHGDGMDEVTTTGVTHVAALEDG
KIRTFDLTPKDFGVEPALMNDLKGGDGIANAAALREVLSGKRNAYRDISLCNAAAALVIAGKAETLSQAMTIASDALDSG
KAAAALDRLVAVSNEANSGQE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=333, Percent_Identity=38.7387387387387, Blast_Score=222, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=31.5950920245399, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_AGRT5 (Q8UER8)

Other databases:

- EMBL:   AE007869
- PIR:   A97563
- PIR:   AI2783
- RefSeq:   NP_354673.1
- ProteinModelPortal:   Q8UER8
- SMR:   Q8UER8
- STRING:   Q8UER8
- GeneID:   1133725
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1687
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- PhylomeDB:   Q8UER8
- ProtClustDB:   PRK00188
- BioCyc:   ATUM176299-1:ATU1687-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35376; Mature: 35245

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELKPLIAKVANGESLNREDARTAFDILMSGEATPSQIGGFLMALRVRGETVDEIVGAV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
SSMRARMLPVSAPANAIDIVGTGGDGIGTYNISTLASIITAGTGLPVAKHGNRALSSKSG
HHHHHHCCCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHCCCCCCCCCCCCHHHCCCCC
TADALSALGVRLDIGPDLIARCIAEAGLGFMFAQMHHSAMRHVGPSRVELGTRTIFNLLG
CHHHHHHCCEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PLSNPAGAKRQLLGVFSPRWLVPLAEVLRDLGSESIWVVHGDGMDEVTTTGVTHVAALED
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCEEEEEECC
GKIRTFDLTPKDFGVEPALMNDLKGGDGIANAAALREVLSGKRNAYRDISLCNAAAALVI
CCEEEEECCCHHCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEE
AGKAETLSQAMTIASDALDSGKAAAALDRLVAVSNEANSGQE
ECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AELKPLIAKVANGESLNREDARTAFDILMSGEATPSQIGGFLMALRVRGETVDEIVGAV
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
SSMRARMLPVSAPANAIDIVGTGGDGIGTYNISTLASIITAGTGLPVAKHGNRALSSKSG
HHHHHHCCCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHCCCCCCCCCCCCHHHCCCCC
TADALSALGVRLDIGPDLIARCIAEAGLGFMFAQMHHSAMRHVGPSRVELGTRTIFNLLG
CHHHHHHCCEEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PLSNPAGAKRQLLGVFSPRWLVPLAEVLRDLGSESIWVVHGDGMDEVTTTGVTHVAALED
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCEEEEEECC
GKIRTFDLTPKDFGVEPALMNDLKGGDGIANAAALREVLSGKRNAYRDISLCNAAAALVI
CCEEEEECCCHHCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEE
AGKAETLSQAMTIASDALDSGKAAAALDRLVAVSNEANSGQE
ECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194