Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 15888991

GI number: 15888991

Start: 1669727

End: 1671619

Strand: Direct

Name: ppiD [H]

Synonym: Atu1686

Alternate gene names: 15888991

Gene position: 1669727-1671619 (Clockwise)

Preceding gene: 15888990

Following gene: 15888992

Centisome position: 58.76

GC content: 62.02

Gene sequence:

>1893_bases
ATGCTCGATTCCCTGAGAAATGCTTCTCGAACCATGGCAGCCAAGCTGCTGCTTCTCCTGCTTGTTGTTTCGTTCGGCGT
CTGGGGCGTCTCCGCATCGCTTGTCACCGCCAATTCCCATGCCGTCATGACGGTGGGCGACCAGACGGTCAGCCCGCAGG
AATTCCGCCTTGCCTATCAGCGCCAGGTTTCCGATCTCAGCCGCCAGTTCGGCACGAGACTGACGACCGAACAGGCCAAG
GCCTTCGGCATCGATCGTCAGGTGTTCAGCCAGCTTGCGGCCGGTGCGGCGCTTGACGAACTGGCTTCGAAGATGAATCT
CGGCCTTTCGGAAAACCGCCTCGCCAACCTCATCGCCGAGGACCCGGCCTTCAAGTCGGTCAACGGTCAGTTCGACCGTA
ATCTCTTCAGCGAGCGCCTGCGCAATTCCGGCTTCCGTGAAGACGACTATATCAAGGAGCGCAGCAAGGTTGCCGTCCGC
AGCCAGATCGTCGAAGCCGTCTCCGATGGTTTTGCCGCACCGCAGGTGCTGGTGGATGCGCTGAAGCAGTATCGCAACGA
ACAGCGCGCCGTCGATTACGTCATTCTGTCCAACGCCGTCATCCCGCCGGTCAAGGCACCGGGCGACGACGTGCTCACAC
CCTGGTTCGAAACCAACAAGTCGAAGTACCGCGCGCCTGAGTTCCGCAAGTTCACCTATGTGAAGCTGGAACCGTCCGAT
ATCGCCGAGCCAGCCTCGGTAACGGACGCGCAGATCGCCGATTATTATAACAGCCACAAGGACAGCTTCCGCACCGCCGG
TCGCCGCACCGTAGAGCAGCTGACCTTCCCGGACAAGGAAATGGCTGCCGCTGCCGCCGAGCAGATCAGGCTCGGCAACA
CCACCTATGACCAGGTGGTGAAGGACCAGGGCAAGACTGCCTCCGATGTTACCCTCGGCGAATTCACCAAGGATACCATC
CCCGACCAGTCGATTGCCGATGCCGCCTTCGCCATCCAGAAGGATGGCGGCGTATCGCCGGTGGTTGATGGTTCCTTCGG
CCCGATCCTTCTGCGCGTCACCGGCATCAAGCCGGAAACCACCCGCACGCTTGATGAAGCCAAGGAAGATATCCGCAAGG
ACCTCGCCACCGCCGCCGCCGCGGAAGAAATCACCAATGTGCATGATCGCTATGAGGATCTGCGCGCCGGTGGCTCTTCG
CTCGCCGATGCCGCCAAGCAGCTCAACCTGAAGCCCGTCACCATTGACGCCATCGACGCCGCCGGCCTCAATGAAAAGGG
CGATGCGATCGAGGGCCTGCCGTCGCCGCAGCTCGCACAGGACGTGTTCAAGACCGAACCCGGCACTGACGCCCTGCCGA
TCAATCTCGGCCGTGAAGGTTATATCTGGTTCGACGTCGAGCAGATCATCCCTGCCCGCGACCGCACGCTTGCCGAAGTC
CGCGACGATGTCGTGGCCGACTGGACGGCAGAGCAGCAGCGCACCGCGCTTGCAGCGAAGGCCGACGAGCTGAAGGCCCG
CGTTGAAAAGGGCGAAACGCTGGAAGCCGTCGCCGGTGAGCTAAGCCTTGCCGTCGAGCAGAAATCCGGCCTGCGCCGCA
CCAGCGAGGATGCGATTTTCGGCCGACAGACCATCGCCGCCGTCTTCTCGGGCGCCGAAGGCGTGGTCGGCACCGCGGCC
GATGCCGACGGTTCCAGCCGTATCCTCTTCAAGGTCACCTCGGTTGACGCCAATGCCCCGGCAGACGCGCTTGCCAATGA
CGACCAGCAGTTTACCGCCATTGCCCGCGCGGCCGGCGACGACATGCTGGATCAGATGGTCAACCGTCTGCAGAATGATT
ATGGTGTGACGATCAACCAGGCCCTCGCCGATCAGGCGATGGTCGGTTTCTAA

Upstream 100 bases:

>100_bases
TTCCCTTCAATTTCCCTTTGGATTGATTTAAGGAACGCCGATACGTTGCGGGCCGGAAGGCTGGCGACCGCGATGACGTT
CCTGTGAGGTTTGCATAACG

Downstream 100 bases:

>100_bases
CCGGGGGGCGAGACATGGCCGAACTGAAGCCGCTGATCGCCAAGGTCGCGAACGGAGAAAGCCTGAACCGCGAGGATGCG
CGCACGGCTTTCGATATTCT

Product: peptidyl-prolyl cis-trans isomerse D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MLDSLRNASRTMAAKLLLLLLVVSFGVWGVSASLVTANSHAVMTVGDQTVSPQEFRLAYQRQVSDLSRQFGTRLTTEQAK
AFGIDRQVFSQLAAGAALDELASKMNLGLSENRLANLIAEDPAFKSVNGQFDRNLFSERLRNSGFREDDYIKERSKVAVR
SQIVEAVSDGFAAPQVLVDALKQYRNEQRAVDYVILSNAVIPPVKAPGDDVLTPWFETNKSKYRAPEFRKFTYVKLEPSD
IAEPASVTDAQIADYYNSHKDSFRTAGRRTVEQLTFPDKEMAAAAAEQIRLGNTTYDQVVKDQGKTASDVTLGEFTKDTI
PDQSIADAAFAIQKDGGVSPVVDGSFGPILLRVTGIKPETTRTLDEAKEDIRKDLATAAAAEEITNVHDRYEDLRAGGSS
LADAAKQLNLKPVTIDAIDAAGLNEKGDAIEGLPSPQLAQDVFKTEPGTDALPINLGREGYIWFDVEQIIPARDRTLAEV
RDDVVADWTAEQQRTALAAKADELKARVEKGETLEAVAGELSLAVEQKSGLRRTSEDAIFGRQTIAAVFSGAEGVVGTAA
DADGSSRILFKVTSVDANAPADALANDDQQFTAIARAAGDDMLDQMVNRLQNDYGVTINQALADQAMVGF

Sequences:

>Translated_630_residues
MLDSLRNASRTMAAKLLLLLLVVSFGVWGVSASLVTANSHAVMTVGDQTVSPQEFRLAYQRQVSDLSRQFGTRLTTEQAK
AFGIDRQVFSQLAAGAALDELASKMNLGLSENRLANLIAEDPAFKSVNGQFDRNLFSERLRNSGFREDDYIKERSKVAVR
SQIVEAVSDGFAAPQVLVDALKQYRNEQRAVDYVILSNAVIPPVKAPGDDVLTPWFETNKSKYRAPEFRKFTYVKLEPSD
IAEPASVTDAQIADYYNSHKDSFRTAGRRTVEQLTFPDKEMAAAAAEQIRLGNTTYDQVVKDQGKTASDVTLGEFTKDTI
PDQSIADAAFAIQKDGGVSPVVDGSFGPILLRVTGIKPETTRTLDEAKEDIRKDLATAAAAEEITNVHDRYEDLRAGGSS
LADAAKQLNLKPVTIDAIDAAGLNEKGDAIEGLPSPQLAQDVFKTEPGTDALPINLGREGYIWFDVEQIIPARDRTLAEV
RDDVVADWTAEQQRTALAAKADELKARVEKGETLEAVAGELSLAVEQKSGLRRTSEDAIFGRQTIAAVFSGAEGVVGTAA
DADGSSRILFKVTSVDANAPADALANDDQQFTAIARAAGDDMLDQMVNRLQNDYGVTINQALADQAMVGF
>Mature_630_residues
MLDSLRNASRTMAAKLLLLLLVVSFGVWGVSASLVTANSHAVMTVGDQTVSPQEFRLAYQRQVSDLSRQFGTRLTTEQAK
AFGIDRQVFSQLAAGAALDELASKMNLGLSENRLANLIAEDPAFKSVNGQFDRNLFSERLRNSGFREDDYIKERSKVAVR
SQIVEAVSDGFAAPQVLVDALKQYRNEQRAVDYVILSNAVIPPVKAPGDDVLTPWFETNKSKYRAPEFRKFTYVKLEPSD
IAEPASVTDAQIADYYNSHKDSFRTAGRRTVEQLTFPDKEMAAAAAEQIRLGNTTYDQVVKDQGKTASDVTLGEFTKDTI
PDQSIADAAFAIQKDGGVSPVVDGSFGPILLRVTGIKPETTRTLDEAKEDIRKDLATAAAAEEITNVHDRYEDLRAGGSS
LADAAKQLNLKPVTIDAIDAAGLNEKGDAIEGLPSPQLAQDVFKTEPGTDALPINLGREGYIWFDVEQIIPARDRTLAEV
RDDVVADWTAEQQRTALAAKADELKARVEKGETLEAVAGELSLAVEQKSGLRRTSEDAIFGRQTIAAVFSGAEGVVGTAA
DADGSSRILFKVTSVDANAPADALANDDQQFTAIARAAGDDMLDQMVNRLQNDYGVTINQALADQAMVGF

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=457, Percent_Identity=25.164113785558, Blast_Score=133, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68250; Mature: 68250

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSLRNASRTMAAKLLLLLLVVSFGVWGVSASLVTANSHAVMTVGDQTVSPQEFRLAYQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEEECCCCCCHHHHHHHHH
RQVSDLSRQFGTRLTTEQAKAFGIDRQVFSQLAAGAALDELASKMNLGLSENRLANLIAE
HHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHC
DPAFKSVNGQFDRNLFSERLRNSGFREDDYIKERSKVAVRSQIVEAVSDGFAAPQVLVDA
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LKQYRNEQRAVDYVILSNAVIPPVKAPGDDVLTPWFETNKSKYRAPEFRKFTYVKLEPSD
HHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEECHHH
IAEPASVTDAQIADYYNSHKDSFRTAGRRTVEQLTFPDKEMAAAAAEQIRLGNTTYDQVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHH
KDQGKTASDVTLGEFTKDTIPDQSIADAAFAIQKDGGVSPVVDGSFGPILLRVTGIKPET
HHCCCCCCCCCHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCCCCCCEEEEEECCCCHH
TRTLDEAKEDIRKDLATAAAAEEITNVHDRYEDLRAGGSSLADAAKQLNLKPVTIDAIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCC
AGLNEKGDAIEGLPSPQLAQDVFKTEPGTDALPINLGREGYIWFDVEQIIPARDRTLAEV
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCEEEEEHHHHCCCCCHHHHHH
RDDVVADWTAEQQRTALAAKADELKARVEKGETLEAVAGELSLAVEQKSGLRRTSEDAIF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GRQTIAAVFSGAEGVVGTAADADGSSRILFKVTSVDANAPADALANDDQQFTAIARAAGD
HHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEEECCCCCCHHHHCCCCHHHHHHHHHHCH
DMLDQMVNRLQNDYGVTINQALADQAMVGF
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLDSLRNASRTMAAKLLLLLLVVSFGVWGVSASLVTANSHAVMTVGDQTVSPQEFRLAYQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEEECCCCCCHHHHHHHHH
RQVSDLSRQFGTRLTTEQAKAFGIDRQVFSQLAAGAALDELASKMNLGLSENRLANLIAE
HHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHC
DPAFKSVNGQFDRNLFSERLRNSGFREDDYIKERSKVAVRSQIVEAVSDGFAAPQVLVDA
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LKQYRNEQRAVDYVILSNAVIPPVKAPGDDVLTPWFETNKSKYRAPEFRKFTYVKLEPSD
HHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEECHHH
IAEPASVTDAQIADYYNSHKDSFRTAGRRTVEQLTFPDKEMAAAAAEQIRLGNTTYDQVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHH
KDQGKTASDVTLGEFTKDTIPDQSIADAAFAIQKDGGVSPVVDGSFGPILLRVTGIKPET
HHCCCCCCCCCHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCCCCCCEEEEEECCCCHH
TRTLDEAKEDIRKDLATAAAAEEITNVHDRYEDLRAGGSSLADAAKQLNLKPVTIDAIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCC
AGLNEKGDAIEGLPSPQLAQDVFKTEPGTDALPINLGREGYIWFDVEQIIPARDRTLAEV
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCEEEEEHHHHCCCCCHHHHHH
RDDVVADWTAEQQRTALAAKADELKARVEKGETLEAVAGELSLAVEQKSGLRRTSEDAIF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GRQTIAAVFSGAEGVVGTAADADGSSRILFKVTSVDANAPADALANDDQQFTAIARAAGD
HHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEEECCCCCCHHHHCCCCHHHHHHHHHHCH
DMLDQMVNRLQNDYGVTINQALADQAMVGF
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]