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The map label for this gene is map [H]

Identifier: 15888919

GI number: 15888919

Start: 1587933

End: 1588769

Strand: Direct

Name: map [H]

Synonym: Atu1606

Alternate gene names: 15888919

Gene position: 1587933-1588769 (Clockwise)

Preceding gene: 15888918

Following gene: 159184835

Centisome position: 55.88

GC content: 62.49

Gene sequence:

>837_bases
ATGATGGTCACCTATATCGACGCAGCCTCCGCCCCCCTCAAGAACACGGGCGTCATCCGCCTCTATACCCCTGAGGATTT
CGATGGCATGCGCAAGGCGTGCCAGTTGACGGCGCGGTGCCTCGATGAGCTGGCGGCGATCGTCAAGCCGGGTGTGACGA
CCGACGCCATCGACCGTTTCGTCTTCGAATTCGGTGCCGACCACGGCGCGCTGCCGGCCACGCTGAATTATCGCGGTTAC
ACGAAATCCGTCTGCACCTCGATCAACCACGTCGTCTGCCACGGCATTCCGGATGAAAAGCCGCTGCGTGATGGCGATAT
CGTCAATATCGACGTCACCTATGTGCTTGACGGTTGGCATGGCGATTCGAGCCGCATGTATCCTGTCGGCCAGATCAAGC
GCGCCGCCGAGCGGCTGATGGAAGTGACCTATGAATGCCTGATGCGCGGTATCGCGGCGGTGAAGCCCGGCACACGCACC
GGCGCGATCGGCGCGGCGATCCAGGCCTATGCGGAAGCGGAACGCTGCTCCGTGGTGCGTGATTTCTGCGGCCACGGCGT
CGGGCGTCTGTTCCACGACACGCCCAATATCCTGCATTACGGCCAGCCGAATGAAGGCCCGGAAATCCGCGAGGGCATGA
TCTTCACCATCGAGCCGATGATCAATCTAGGCAAGCCGCATGTGAAGGTGCTCTCCGATGGCTGGACGGCGGTGACCCGC
GACCGCTCCCTCTCTGCGCAATATGAACATGCCGTCGGCGTCACCGCCACCGGCTGTGAAATCTTCACGTTGTCGCCCGG
CGGCTTCGATCGCCCGGGCTTGCCGCCGCTCGCATAA

Upstream 100 bases:

>100_bases
GCGGTCTCGCCGACACAAATTTCGGTCAGCGGAACGGTTAAGATGGACGAATGGCGTCCGGCTGTTTTATGAACAGGGAC
GTAAAGACACAGAAAGCACT

Downstream 100 bases:

>100_bases
GGCCAGACCGCCTATGGCAAAACGCCCTGCCCTGCCTTCCGCCGATCTTTCCCCGACGTCAGGCTTTGAGGCTGGCGAAG
GCGATCTGTTCAACGGGGCG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MMVTYIDAASAPLKNTGVIRLYTPEDFDGMRKACQLTARCLDELAAIVKPGVTTDAIDRFVFEFGADHGALPATLNYRGY
TKSVCTSINHVVCHGIPDEKPLRDGDIVNIDVTYVLDGWHGDSSRMYPVGQIKRAAERLMEVTYECLMRGIAAVKPGTRT
GAIGAAIQAYAEAERCSVVRDFCGHGVGRLFHDTPNILHYGQPNEGPEIREGMIFTIEPMINLGKPHVKVLSDGWTAVTR
DRSLSAQYEHAVGVTATGCEIFTLSPGGFDRPGLPPLA

Sequences:

>Translated_278_residues
MMVTYIDAASAPLKNTGVIRLYTPEDFDGMRKACQLTARCLDELAAIVKPGVTTDAIDRFVFEFGADHGALPATLNYRGY
TKSVCTSINHVVCHGIPDEKPLRDGDIVNIDVTYVLDGWHGDSSRMYPVGQIKRAAERLMEVTYECLMRGIAAVKPGTRT
GAIGAAIQAYAEAERCSVVRDFCGHGVGRLFHDTPNILHYGQPNEGPEIREGMIFTIEPMINLGKPHVKVLSDGWTAVTR
DRSLSAQYEHAVGVTATGCEIFTLSPGGFDRPGLPPLA
>Mature_278_residues
MMVTYIDAASAPLKNTGVIRLYTPEDFDGMRKACQLTARCLDELAAIVKPGVTTDAIDRFVFEFGADHGALPATLNYRGY
TKSVCTSINHVVCHGIPDEKPLRDGDIVNIDVTYVLDGWHGDSSRMYPVGQIKRAAERLMEVTYECLMRGIAAVKPGTRT
GAIGAAIQAYAEAERCSVVRDFCGHGVGRLFHDTPNILHYGQPNEGPEIREGMIFTIEPMINLGKPHVKVLSDGWTAVTR
DRSLSAQYEHAVGVTATGCEIFTLSPGGFDRPGLPPLA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=258, Percent_Identity=47.2868217054264, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=41.9354838709677, Blast_Score=205, Evalue=5e-53,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=52.4193548387097, Blast_Score=259, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71996291, Length=260, Percent_Identity=46.1538461538462, Blast_Score=233, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=45.0980392156863, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=44.8979591836735, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24583427, Length=253, Percent_Identity=43.0830039525692, Blast_Score=209, Evalue=2e-54,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30226; Mature: 30226

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVTYIDAASAPLKNTGVIRLYTPEDFDGMRKACQLTARCLDELAAIVKPGVTTDAIDRF
CEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VFEFGADHGALPATLNYRGYTKSVCTSINHVVCHGIPDEKPLRDGDIVNIDVTYVLDGWH
HHHHCCCCCCCCCEEECCCCHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEEEEECEE
GDSSRMYPVGQIKRAAERLMEVTYECLMRGIAAVKPGTRTGAIGAAIQAYAEAERCSVVR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DFCGHGVGRLFHDTPNILHYGQPNEGPEIREGMIFTIEPMINLGKPHVKVLSDGWTAVTR
HHHCCCHHHHHCCCCCEEECCCCCCCCHHHCCEEEEEECHHCCCCCCEEEEECCCEEEEC
DRSLSAQYEHAVGVTATGCEIFTLSPGGFDRPGLPPLA
CCCCCCHHHHHCCEEECCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MMVTYIDAASAPLKNTGVIRLYTPEDFDGMRKACQLTARCLDELAAIVKPGVTTDAIDRF
CEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VFEFGADHGALPATLNYRGYTKSVCTSINHVVCHGIPDEKPLRDGDIVNIDVTYVLDGWH
HHHHCCCCCCCCCEEECCCCHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEEEEECEE
GDSSRMYPVGQIKRAAERLMEVTYECLMRGIAAVKPGTRTGAIGAAIQAYAEAERCSVVR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DFCGHGVGRLFHDTPNILHYGQPNEGPEIREGMIFTIEPMINLGKPHVKVLSDGWTAVTR
HHHCCCHHHHHCCCCCEEECCCCCCCCHHHCCEEEEEECHHCCCCCCEEEEECCCEEEEC
DRSLSAQYEHAVGVTATGCEIFTLSPGGFDRPGLPPLA
CCCCCCHHHHHCCEEECCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]