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The map label for this gene is ntrY [H]

Identifier: 15888772

GI number: 15888772

Start: 1440899

End: 1443160

Strand: Direct

Name: ntrY [H]

Synonym: Atu1447

Alternate gene names: 15888772

Gene position: 1440899-1443160 (Clockwise)

Preceding gene: 15888771

Following gene: 15888773

Centisome position: 50.71

GC content: 59.95

Gene sequence:

>2262_bases
ATGCGGAAACCCGCCGCCGAACACGACGTTGCCGACGAGGCAGCGGGAATGGTGGTTGCCGATCGCAGGATGTCATTTGC
CCTGCCGGGGCTGGTGCTCGCCGGCGTTGCCCTTGTCTGTGCTATCATCACCCTCTTCGTGCTTATGGGCGTGACGCCGA
TTGCGCCGACGACCAATGTCGTCATCGCCTCGGTGGTGATCAATTCGATCTTGGTGATCGGCCTGATCTTCCTTATCGGC
CGCGAAATCAACCGGCTGCTGAAGGCGCGTAAAAAGGGCAGGGCGGCGGCACGACTGCATGTTCGCATCGTCGTGCTTTT
CTCCATCGTCGCGATCACGCCCGCTGTCCTTGTCGCCATCTTCGCCAGTCTGACGCTGAATGTCGGTCTCGACCGCTGGT
TTTCGATCCGCACCCAGTCGATCGTCGAGTCGTCGGGCAATATCGCTCAAGCCTATATGATGGAAAACGCCGGTTATCTT
CAGGGCCAGACCCTATCGATGGCCACCGACCTCGATCGCAATCGCGCACTTTTTTATCTTGATCGTACCGGCTTCGTCGA
TCTGATGACGCGTCAGGCCAAGGGCCGCGGCCTGCTCGGCGCGTTTCTGGTGCAGGAGGATGGCGACGCGGTTGCCCAGG
CCGATATCAAGACGGAAAAACCGCTTCCCGCTATTCCGCACGACGCGCTCGAGAAAGCAGCCGCCGGTCAACCGACCCTT
ATCCCGCCCGGTATTACCAACCTTGTTGGCGCCATCATCAAGCTCGAAGGCATCAGCGGCACCTTCCTTTATACGGTGCG
TGCGGTCGATCCGAAGGTCATGACCGCGATGCGGCTGATGGAAGAGAACCGTGCGGAATACAAGAATATGGAGGCGGGCC
GCGCGCCGCTGCAGATCGCCTTTGCGATCCTCTATCTCGGTTTTGCGCTGATCGTGCTTCTGGTCGCCATCTGGACGGCA
ATCGCGGTGGCCGACCGGATCGTCCGCCCGATTCGTCTTCTCATCAGCGCCGCCGACAGTGTCGCCACGGGCAACATGCA
TGTGCTGGTTCCCGTGCGCGCTGTCGATGGCGACGTCGGGCGCCTGTCGCGTACCTTCAACAAGATGGTCTCGGAACTGC
GCAGCCAGCAGGAGCAGATCATCGAGGCCAAGGACGATATCGACGACCGCCGCCGCTTCATCGAAGCCGTGCTGTCGGGT
GTGACCGCCGCTGTCATCGGCATTGATGAGAACCGCAGGATCACCATCGTCAACCCGTCCGGCGAGGAATTCCTGGCGCT
GAATTTCGACCAGCTGCTCGGCGCGCAGCTTTCCGAGATCGCACCTGAGATTGATCAGGTCGTGACCGAGGCGAACACCT
GGGCGCGCGGCAACTTCCGCAAGCAGATCAATATCATGCGACGGGGCAAGGAACGCACGCTGAATGTGCAGGTCACCCGC
GAGGATGCCCGCGACGGCCGCGACAGCTATGTCATCACCCTCGACGACATTACCGATCTCGTCATCGCCCAGCGCTCCAC
CGCATGGTCGGATGTGGCACGGCGTATTGCCCATGAAATCAAGAACCCGCTGACGCCGATCCAGCTTTCCGCAGAGCGCA
TCAAGCGCCGTTTCGGCAAGCAGATCGACGAAAACGATCGCGCCATCTTCGATCAGTGTACGGACACCATTGTCCGGCAG
GTCGGTGATATCGGCCGCATGGTGGATGAATTCTCGGCCTTTGCGCGTATGCCAAAGCCGACGAAGGAAAAGTCGGACCT
GCGGTCGATCCTCAAGGACGCGGCCTTCCTCCGGGAAATCAGCGCCGCCGACACGAAATTCTCAACGGAGTTCGGCGATA
TCCCGCTGGAGGGCATGTTCGATGCCCGCATGCTGGGACAGGCCTTCGGCAATCTCATCAAGAATGCGACGGAAGCGATC
GAAGCGGTGGAAGGCGAAAAGCGGCCGGGTAAAATCCTGGTGCGCGCCTCTTTTGATGAGGCCAATTCGCGTTTCGTGGC
TGACATTATCGACAATGGCCGCGGCCTTCCCGTCGAGAACCGTCATCGCATTCTCGAACCCTATATGACGATGCGGGACA
AGGGCACGGGCCTTGGTCTGGCCATCGTCAAGAAGATCATTGAAGAACATGGCGGGTATCTGGAACTTCACGATGCCCCT
GCCGAATTCGACCATGGCCATGGCGCCATGATCCGAGTGCTGCTGCCCTATATCGAGGCGGTCGGCGGCGAAAATAACAA
GGAAGCAGCATATGGCGTCTGA

Upstream 100 bases:

>100_bases
TGCTTGGAAAACACTAGGAAGGATATAGATTCGCCTGATGGGGGAGTCTTGCCTGACTTCAGGACTGTGGTGCTGGCTGG
CCAGCAATTGGGAGTAATGC

Downstream 100 bases:

>100_bases
TATTTTGGTCGTGGATGACGAGGCGGACATTCGCGAAATCGTAGCGGGCATCCTGTCCGATGAGGGCCACGAGACGCGTA
TGGCCTTCGACAGCGACAGC

Product: two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 753

Protein sequence:

>753_residues
MRKPAAEHDVADEAAGMVVADRRMSFALPGLVLAGVALVCAIITLFVLMGVTPIAPTTNVVIASVVINSILVIGLIFLIG
REINRLLKARKKGRAAARLHVRIVVLFSIVAITPAVLVAIFASLTLNVGLDRWFSIRTQSIVESSGNIAQAYMMENAGYL
QGQTLSMATDLDRNRALFYLDRTGFVDLMTRQAKGRGLLGAFLVQEDGDAVAQADIKTEKPLPAIPHDALEKAAAGQPTL
IPPGITNLVGAIIKLEGISGTFLYTVRAVDPKVMTAMRLMEENRAEYKNMEAGRAPLQIAFAILYLGFALIVLLVAIWTA
IAVADRIVRPIRLLISAADSVATGNMHVLVPVRAVDGDVGRLSRTFNKMVSELRSQQEQIIEAKDDIDDRRRFIEAVLSG
VTAAVIGIDENRRITIVNPSGEEFLALNFDQLLGAQLSEIAPEIDQVVTEANTWARGNFRKQINIMRRGKERTLNVQVTR
EDARDGRDSYVITLDDITDLVIAQRSTAWSDVARRIAHEIKNPLTPIQLSAERIKRRFGKQIDENDRAIFDQCTDTIVRQ
VGDIGRMVDEFSAFARMPKPTKEKSDLRSILKDAAFLREISAADTKFSTEFGDIPLEGMFDARMLGQAFGNLIKNATEAI
EAVEGEKRPGKILVRASFDEANSRFVADIIDNGRGLPVENRHRILEPYMTMRDKGTGLGLAIVKKIIEEHGGYLELHDAP
AEFDHGHGAMIRVLLPYIEAVGGENNKEAAYGV

Sequences:

>Translated_753_residues
MRKPAAEHDVADEAAGMVVADRRMSFALPGLVLAGVALVCAIITLFVLMGVTPIAPTTNVVIASVVINSILVIGLIFLIG
REINRLLKARKKGRAAARLHVRIVVLFSIVAITPAVLVAIFASLTLNVGLDRWFSIRTQSIVESSGNIAQAYMMENAGYL
QGQTLSMATDLDRNRALFYLDRTGFVDLMTRQAKGRGLLGAFLVQEDGDAVAQADIKTEKPLPAIPHDALEKAAAGQPTL
IPPGITNLVGAIIKLEGISGTFLYTVRAVDPKVMTAMRLMEENRAEYKNMEAGRAPLQIAFAILYLGFALIVLLVAIWTA
IAVADRIVRPIRLLISAADSVATGNMHVLVPVRAVDGDVGRLSRTFNKMVSELRSQQEQIIEAKDDIDDRRRFIEAVLSG
VTAAVIGIDENRRITIVNPSGEEFLALNFDQLLGAQLSEIAPEIDQVVTEANTWARGNFRKQINIMRRGKERTLNVQVTR
EDARDGRDSYVITLDDITDLVIAQRSTAWSDVARRIAHEIKNPLTPIQLSAERIKRRFGKQIDENDRAIFDQCTDTIVRQ
VGDIGRMVDEFSAFARMPKPTKEKSDLRSILKDAAFLREISAADTKFSTEFGDIPLEGMFDARMLGQAFGNLIKNATEAI
EAVEGEKRPGKILVRASFDEANSRFVADIIDNGRGLPVENRHRILEPYMTMRDKGTGLGLAIVKKIIEEHGGYLELHDAP
AEFDHGHGAMIRVLLPYIEAVGGENNKEAAYGV
>Mature_753_residues
MRKPAAEHDVADEAAGMVVADRRMSFALPGLVLAGVALVCAIITLFVLMGVTPIAPTTNVVIASVVINSILVIGLIFLIG
REINRLLKARKKGRAAARLHVRIVVLFSIVAITPAVLVAIFASLTLNVGLDRWFSIRTQSIVESSGNIAQAYMMENAGYL
QGQTLSMATDLDRNRALFYLDRTGFVDLMTRQAKGRGLLGAFLVQEDGDAVAQADIKTEKPLPAIPHDALEKAAAGQPTL
IPPGITNLVGAIIKLEGISGTFLYTVRAVDPKVMTAMRLMEENRAEYKNMEAGRAPLQIAFAILYLGFALIVLLVAIWTA
IAVADRIVRPIRLLISAADSVATGNMHVLVPVRAVDGDVGRLSRTFNKMVSELRSQQEQIIEAKDDIDDRRRFIEAVLSG
VTAAVIGIDENRRITIVNPSGEEFLALNFDQLLGAQLSEIAPEIDQVVTEANTWARGNFRKQINIMRRGKERTLNVQVTR
EDARDGRDSYVITLDDITDLVIAQRSTAWSDVARRIAHEIKNPLTPIQLSAERIKRRFGKQIDENDRAIFDQCTDTIVRQ
VGDIGRMVDEFSAFARMPKPTKEKSDLRSILKDAAFLREISAADTKFSTEFGDIPLEGMFDARMLGQAFGNLIKNATEAI
EAVEGEKRPGKILVRASFDEANSRFVADIIDNGRGLPVENRHRILEPYMTMRDKGTGLGLAIVKKIIEEHGGYLELHDAP
AEFDHGHGAMIRVLLPYIEAVGGENNKEAAYGV

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=403, Percent_Identity=21.8362282878412, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790300, Length=346, Percent_Identity=22.8323699421965, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=26.3829787234043, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789808, Length=229, Percent_Identity=27.5109170305677, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1790346, Length=211, Percent_Identity=27.9620853080569, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82658; Mature: 82658

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPAAEHDVADEAAGMVVADRRMSFALPGLVLAGVALVCAIITLFVLMGVTPIAPTTNV
CCCCCCCCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VIASVVINSILVIGLIFLIGREINRLLKARKKGRAAARLHVRIVVLFSIVAITPAVLVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FASLTLNVGLDRWFSIRTQSIVESSGNIAQAYMMENAGYLQGQTLSMATDLDRNRALFYL
HHHHHHHCCHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCHHHHCCCCCCEEEEE
DRTGFVDLMTRQAKGRGLLGAFLVQEDGDAVAQADIKTEKPLPAIPHDALEKAAAGQPTL
ECCCHHHHHHHHCCCCCCEEEEEEECCCCHHEECCCCCCCCCCCCCHHHHHHHHCCCCCC
IPPGITNLVGAIIKLEGISGTFLYTVRAVDPKVMTAMRLMEENRAEYKNMEAGRAPLQIA
CCCCHHHHHHHHHEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FAILYLGFALIVLLVAIWTAIAVADRIVRPIRLLISAADSVATGNMHVLVPVRAVDGDVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH
RLSRTFNKMVSELRSQQEQIIEAKDDIDDRRRFIEAVLSGVTAAVIGIDENRRITIVNPS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCC
GEEFLALNFDQLLGAQLSEIAPEIDQVVTEANTWARGNFRKQINIMRRGKERTLNVQVTR
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEEEC
EDARDGRDSYVITLDDITDLVIAQRSTAWSDVARRIAHEIKNPLTPIQLSAERIKRRFGK
CCCCCCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
QIDENDRAIFDQCTDTIVRQVGDIGRMVDEFSAFARMPKPTKEKSDLRSILKDAAFLREI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SAADTKFSTEFGDIPLEGMFDARMLGQAFGNLIKNATEAIEAVEGEKRPGKILVRASFDE
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
ANSRFVADIIDNGRGLPVENRHRILEPYMTMRDKGTGLGLAIVKKIIEEHGGYLELHDAP
CCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCC
AEFDHGHGAMIRVLLPYIEAVGGENNKEAAYGV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRKPAAEHDVADEAAGMVVADRRMSFALPGLVLAGVALVCAIITLFVLMGVTPIAPTTNV
CCCCCCCCCCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VIASVVINSILVIGLIFLIGREINRLLKARKKGRAAARLHVRIVVLFSIVAITPAVLVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FASLTLNVGLDRWFSIRTQSIVESSGNIAQAYMMENAGYLQGQTLSMATDLDRNRALFYL
HHHHHHHCCHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCHHHHCCCCCCEEEEE
DRTGFVDLMTRQAKGRGLLGAFLVQEDGDAVAQADIKTEKPLPAIPHDALEKAAAGQPTL
ECCCHHHHHHHHCCCCCCEEEEEEECCCCHHEECCCCCCCCCCCCCHHHHHHHHCCCCCC
IPPGITNLVGAIIKLEGISGTFLYTVRAVDPKVMTAMRLMEENRAEYKNMEAGRAPLQIA
CCCCHHHHHHHHHEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FAILYLGFALIVLLVAIWTAIAVADRIVRPIRLLISAADSVATGNMHVLVPVRAVDGDVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH
RLSRTFNKMVSELRSQQEQIIEAKDDIDDRRRFIEAVLSGVTAAVIGIDENRRITIVNPS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCC
GEEFLALNFDQLLGAQLSEIAPEIDQVVTEANTWARGNFRKQINIMRRGKERTLNVQVTR
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEEEC
EDARDGRDSYVITLDDITDLVIAQRSTAWSDVARRIAHEIKNPLTPIQLSAERIKRRFGK
CCCCCCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
QIDENDRAIFDQCTDTIVRQVGDIGRMVDEFSAFARMPKPTKEKSDLRSILKDAAFLREI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SAADTKFSTEFGDIPLEGMFDARMLGQAFGNLIKNATEAIEAVEGEKRPGKILVRASFDE
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
ANSRFVADIIDNGRGLPVENRHRILEPYMTMRDKGTGLGLAIVKKIIEEHGGYLELHDAP
CCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCC
AEFDHGHGAMIRVLLPYIEAVGGENNKEAAYGV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]