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The map label for this gene is dgoD1 [H]

Identifier: 15888732

GI number: 15888732

Start: 1400578

End: 1401780

Strand: Direct

Name: dgoD1 [H]

Synonym: Atu1406

Alternate gene names: 15888732

Gene position: 1400578-1401780 (Clockwise)

Preceding gene: 159184742

Following gene: 15888733

Centisome position: 49.29

GC content: 60.35

Gene sequence:

>1203_bases
ATGAAGATTACGTCTGTCGAAACTTTGCGGACCGAGGAGTTCTCAAATGTGCTTTGGGTGCGCATCCACACCGATGCCGG
GGTGATCGGGCTGGGTGAGACCTTCTATGGCGCAGGCGCGGTCGAGGCTCATATCCACGATGTGCTCGCCGGTCGCCTGC
TTGGCCGCGACCCGATGCGGATTGAAGCGCATTCCCGCGAACTGGTGAATCTGCCGATGGCGCAGGCCTCGACCGGTGCC
GAATATCGTGCGGCTTCGGCGATCGATCTGGCACTGTGGGATATTTTCGGCAAGGTCTGCAATCAGCCGGTCCATCAGAT
GCTGGGCGGCCTCTGCCACGATCGTATTCCCGTCTACAACACCTGCGCCGGTTACGGCTATGTGCGGTCCAACAAGATCA
AGCCGGTCGATACCTGGAATTTTCGCGACGATGCCGAAGGCCCCTATGAAGATCTCAGGGCGTTCATGACGGATGCGGGC
GCACTTGCCGAAAACCTGCTGGAGCAGGGCATTTCGGCCATGAAGATCTGGCCCTTCGATCCCGCGGCCATCGAAAACGA
CGGGCGCTACATCACCAGCGAGCAGCTGCGCGCAGCCCTTTTGCCGTTCGAGCAGATACGCAAACGTGTGGGTGACCGCA
TGCAGATCATGGTGGAGTTTCATAGCCTCTGGAACCTGCCGACGATCAAGAAGATCGCCCGCGAACTCGAGGCCTTCGAT
CCGACATGGTACGAAGATCCGATACGGATGAACTCGGTATCCGCCCTTTCGGAACTCGCCGCCTCCACCAGCGTGCCGAT
CTGTGCCTCGGAAACGCTCGGTTCCCGTTTCCCCTACAAGGACATGCTGGAAGCCGGCGCGATCGGCATCGTCATGACCG
ATCTGGTCTGGACAGGCGGTCTGACCGAAGGCCGCAAGATCGCCGCATTGGCCGATACCTATCATCGCCCCTATGCGCCG
CATGATTGCACCGGGCCTGTCGCCTATGCCGCAGCCGTCCATTCCTCCTTTTCGCAGACCAACACCATGATCCAGGAGTC
GGTGCGCGCTTTTTACACCGGCTGGTACTGCGAGCTGGTGACAAATCTGCCCGTCATCGAAAACGGCTTCGTGCTGCCGA
TGGAAGGACCCGGCCTCGGGACCGAATTGCTGCCCAAGGTCTTCGAGCGGCCGGACCTGACGGTCCGCGTCAGCACGCTG
TGA

Upstream 100 bases:

>100_bases
GTGAAATTTTACAAGCAACATTATTGTCCTGATCGAGACTGGCTGGGAGGCTGGTCAGTCAATCGGGAGACGCGACCGAG
GTGGGCGCGCGGAGGAGCTA

Downstream 100 bases:

>100_bases
GGAGGGCATCATGAGCAATCAGATCATCTTCGATCTCGGCGGGCGCACGGCGCTTGTTACCGGTTCTTCACGCGGCCTCG
GCCGCGCAATGGCAGAAGGA

Product: isomerase/lactonizing enzyme

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKITSVETLRTEEFSNVLWVRIHTDAGVIGLGETFYGAGAVEAHIHDVLAGRLLGRDPMRIEAHSRELVNLPMAQASTGA
EYRAASAIDLALWDIFGKVCNQPVHQMLGGLCHDRIPVYNTCAGYGYVRSNKIKPVDTWNFRDDAEGPYEDLRAFMTDAG
ALAENLLEQGISAMKIWPFDPAAIENDGRYITSEQLRAALLPFEQIRKRVGDRMQIMVEFHSLWNLPTIKKIARELEAFD
PTWYEDPIRMNSVSALSELAASTSVPICASETLGSRFPYKDMLEAGAIGIVMTDLVWTGGLTEGRKIAALADTYHRPYAP
HDCTGPVAYAAAVHSSFSQTNTMIQESVRAFYTGWYCELVTNLPVIENGFVLPMEGPGLGTELLPKVFERPDLTVRVSTL

Sequences:

>Translated_400_residues
MKITSVETLRTEEFSNVLWVRIHTDAGVIGLGETFYGAGAVEAHIHDVLAGRLLGRDPMRIEAHSRELVNLPMAQASTGA
EYRAASAIDLALWDIFGKVCNQPVHQMLGGLCHDRIPVYNTCAGYGYVRSNKIKPVDTWNFRDDAEGPYEDLRAFMTDAG
ALAENLLEQGISAMKIWPFDPAAIENDGRYITSEQLRAALLPFEQIRKRVGDRMQIMVEFHSLWNLPTIKKIARELEAFD
PTWYEDPIRMNSVSALSELAASTSVPICASETLGSRFPYKDMLEAGAIGIVMTDLVWTGGLTEGRKIAALADTYHRPYAP
HDCTGPVAYAAAVHSSFSQTNTMIQESVRAFYTGWYCELVTNLPVIENGFVLPMEGPGLGTELLPKVFERPDLTVRVSTL
>Mature_400_residues
MKITSVETLRTEEFSNVLWVRIHTDAGVIGLGETFYGAGAVEAHIHDVLAGRLLGRDPMRIEAHSRELVNLPMAQASTGA
EYRAASAIDLALWDIFGKVCNQPVHQMLGGLCHDRIPVYNTCAGYGYVRSNKIKPVDTWNFRDDAEGPYEDLRAFMTDAG
ALAENLLEQGISAMKIWPFDPAAIENDGRYITSEQLRAALLPFEQIRKRVGDRMQIMVEFHSLWNLPTIKKIARELEAFD
PTWYEDPIRMNSVSALSELAASTSVPICASETLGSRFPYKDMLEAGAIGIVMTDLVWTGGLTEGRKIAALADTYHRPYAP
HDCTGPVAYAAAVHSSFSQTNTMIQESVRAFYTGWYCELVTNLPVIENGFVLPMEGPGLGTELLPKVFERPDLTVRVSTL

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=390, Percent_Identity=32.3076923076923, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1787864, Length=409, Percent_Identity=26.8948655256724, Blast_Score=115, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 44304; Mature: 44304

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITSVETLRTEEFSNVLWVRIHTDAGVIGLGETFYGAGAVEAHIHDVLAGRLLGRDPMR
CCCCCHHHHHHHHHCCEEEEEEECCCCEEECCHHHHCCCHHHHHHHHHHHHHHHCCCCCE
IEAHSRELVNLPMAQASTGAEYRAASAIDLALWDIFGKVCNQPVHQMLGGLCHDRIPVYN
EECCCHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
TCAGYGYVRSNKIKPVDTWNFRDDAEGPYEDLRAFMTDAGALAENLLEQGISAMKIWPFD
CCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PAAIENDGRYITSEQLRAALLPFEQIRKRVGDRMQIMVEFHSLWNLPTIKKIARELEAFD
CCCCCCCCCEECHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PTWYEDPIRMNSVSALSELAASTSVPICASETLGSRFPYKDMLEAGAIGIVMTDLVWTGG
CCCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHCCCCCHHHHHHCCCHHHHHHHHHHCCC
LTEGRKIAALADTYHRPYAPHDCTGPVAYAAAVHSSFSQTNTMIQESVRAFYTGWYCELV
CCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLPVIENGFVLPMEGPGLGTELLPKVFERPDLTVRVSTL
HCCCEECCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MKITSVETLRTEEFSNVLWVRIHTDAGVIGLGETFYGAGAVEAHIHDVLAGRLLGRDPMR
CCCCCHHHHHHHHHCCEEEEEEECCCCEEECCHHHHCCCHHHHHHHHHHHHHHHCCCCCE
IEAHSRELVNLPMAQASTGAEYRAASAIDLALWDIFGKVCNQPVHQMLGGLCHDRIPVYN
EECCCHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCC
TCAGYGYVRSNKIKPVDTWNFRDDAEGPYEDLRAFMTDAGALAENLLEQGISAMKIWPFD
CCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PAAIENDGRYITSEQLRAALLPFEQIRKRVGDRMQIMVEFHSLWNLPTIKKIARELEAFD
CCCCCCCCCEECHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PTWYEDPIRMNSVSALSELAASTSVPICASETLGSRFPYKDMLEAGAIGIVMTDLVWTGG
CCCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHCCCCCHHHHHHCCCHHHHHHHHHHCCC
LTEGRKIAALADTYHRPYAPHDCTGPVAYAAAVHSSFSQTNTMIQESVRAFYTGWYCELV
CCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLPVIENGFVLPMEGPGLGTELLPKVFERPDLTVRVSTL
HCCCEECCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA