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The map label for this gene is hit [H]

Identifier: 15888695

GI number: 15888695

Start: 1363999

End: 1364427

Strand: Reverse

Name: hit [H]

Synonym: Atu1369

Alternate gene names: 15888695

Gene position: 1364427-1363999 (Counterclockwise)

Preceding gene: 15888696

Following gene: 159184732

Centisome position: 48.02

GC content: 59.21

Gene sequence:

>429_bases
ATGGCCAGCGCCTATGACGACAACAATATCTTCGCAAAAATCCTGCGCGGCGAAATTCCGAGCCACAAGCTTTATGAAGA
TGAGCATACGCTGGCCTTCATGGATGTGATGCCGCAGGCACCCGGCCATCTGCTCGTCGTTCCCAAGACCGGCTCCCGCA
ATCTGCTCGATGCCGACCCTCAAGTGCTGGCAAGAACCATTGCCGTGGTGCAGAAACTCGCCGTAGCCGCCAAGGAAGCT
TTCAATGCGGATGGCGTCTTCGTCGCGCAGTTCAACGAACCGGCGGCCGGCCAGACGGTGTTCCACCTGCATTTCCACGT
CATTCCGCGCAAGGAAGGCGAGCCGTTGAAACCGCATTCCGGTGCCATGGCCGACGGCGAGGTGCTGAAGGCTCATGCGG
AGAAGATAAGGGCGGCGCTTGCTTCGTGA

Upstream 100 bases:

>100_bases
CGAGCATATCGGCGATTATCTTGATGAACACACGCCCTTCCGCAAGGGCGAGAGACAGGAACACGAACCGGACGCATAGT
CCGCGACGAGGAGATCACCG

Downstream 100 bases:

>100_bases
CGCTGGCTAAACACGCAACGTCATCCTCGGCCTTGTGCCGAGGATCTAACCACGTATCGTGAAATCAATCGGTTGCAGAT
GCTCGGGACAGGCCCGAGCA

Product: HIT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MASAYDDNNIFAKILRGEIPSHKLYEDEHTLAFMDVMPQAPGHLLVVPKTGSRNLLDADPQVLARTIAVVQKLAVAAKEA
FNADGVFVAQFNEPAAGQTVFHLHFHVIPRKEGEPLKPHSGAMADGEVLKAHAEKIRAALAS

Sequences:

>Translated_142_residues
MASAYDDNNIFAKILRGEIPSHKLYEDEHTLAFMDVMPQAPGHLLVVPKTGSRNLLDADPQVLARTIAVVQKLAVAAKEA
FNADGVFVAQFNEPAAGQTVFHLHFHVIPRKEGEPLKPHSGAMADGEVLKAHAEKIRAALAS
>Mature_141_residues
ASAYDDNNIFAKILRGEIPSHKLYEDEHTLAFMDVMPQAPGHLLVVPKTGSRNLLDADPQVLARTIAVVQKLAVAAKEAF
NADGVFVAQFNEPAAGQTVFHLHFHVIPRKEGEPLKPHSGAMADGEVLKAHAEKIRAALAS

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=109, Percent_Identity=37.6146788990826, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI14211923, Length=107, Percent_Identity=35.5140186915888, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1787346, Length=118, Percent_Identity=34.7457627118644, Blast_Score=66, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17506713, Length=109, Percent_Identity=37.6146788990826, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320078, Length=107, Percent_Identity=39.2523364485981, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581222, Length=114, Percent_Identity=38.5964912280702, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28574010, Length=114, Percent_Identity=38.5964912280702, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15370; Mature: 15239

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAYDDNNIFAKILRGEIPSHKLYEDEHTLAFMDVMPQAPGHLLVVPKTGSRNLLDADP
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCH
QVLARTIAVVQKLAVAAKEAFNADGVFVAQFNEPAAGQTVFHLHFHVIPRKEGEPLKPHS
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCC
GAMADGEVLKAHAEKIRAALAS
CCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASAYDDNNIFAKILRGEIPSHKLYEDEHTLAFMDVMPQAPGHLLVVPKTGSRNLLDADP
CCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCH
QVLARTIAVVQKLAVAAKEAFNADGVFVAQFNEPAAGQTVFHLHFHVIPRKEGEPLKPHS
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCC
GAMADGEVLKAHAEKIRAALAS
CCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]