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The map label for this gene is nrdR

Identifier: 15888504

GI number: 15888504

Start: 1161411

End: 1161890

Strand: Direct

Name: nrdR

Synonym: Atu1166

Alternate gene names: 15888504

Gene position: 1161411-1161890 (Clockwise)

Preceding gene: 159184645

Following gene: 15888505

Centisome position: 40.87

GC content: 60.42

Gene sequence:

>480_bases
ATGCGCTGCCCATTTTGCGGTTCCGAAGACACACAGGTCAAGGACTCGCGTCCGGCGGAGGACAACACCTCCATCCGTCG
GCGGCGCATCTGCCCGGATTGCGGCGGCCGCTTCACGACCTATGAGCGCGTGCAACTGCGCGAGCTGATGGTCATCAAGA
AAAGCGGCCGCAAGCTGCCGTTTGACCGGGAAAAGCTGGTTCGCTCCTTCGAAATCGCGCTGCGCAAGCGCCCGGTTGAT
CGCGACCGGATCGAGCGGGCCGTTTCCGGCATTGCCCGCCGTCTGGAAAGTTCCGGCGAGACGGAAATTCCCTCGGAAGA
AATCGGCCTTCAGGTTCTGGAGGCGCTGAAGAGTCTCGATGACGTGGCCTTTGTGCGCTACGCTTCGGTCTATCGCGATT
TCAGCCATGCCGAGGATTTCGAAAACGTGATTGCCGAAATCAACGCCAAGATCGCCCGAGATACAGACGCCGGAGCATAG

Upstream 100 bases:

>100_bases
GGATGAAGGTAATGCCTCCGTCGAGGCTGCCGTGCGCGAAAAGGTCGTCGGTTTGACCGACCGTTTCCCGATGTATCCGT
ACATGTAAGGAAAGAAAAAG

Downstream 100 bases:

>100_bases
CCGTGACGAGCCGCGCCGATGACGAAAAATTCATGGCCCGTGCAATCGAGGTTTCGCTTCGCCACCAGGGCCAGACGCTG
ACCAATCCCTCGGTTGGCTG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRCPFCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTYERVQLRELMVIKKSGRKLPFDREKLVRSFEIALRKRPVD
RDRIERAVSGIARRLESSGETEIPSEEIGLQVLEALKSLDDVAFVRYASVYRDFSHAEDFENVIAEINAKIARDTDAGA

Sequences:

>Translated_159_residues
MRCPFCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTYERVQLRELMVIKKSGRKLPFDREKLVRSFEIALRKRPVD
RDRIERAVSGIARRLESSGETEIPSEEIGLQVLEALKSLDDVAFVRYASVYRDFSHAEDFENVIAEINAKIARDTDAGA
>Mature_159_residues
MRCPFCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTYERVQLRELMVIKKSGRKLPFDREKLVRSFEIALRKRPVD
RDRIERAVSGIARRLESSGETEIPSEEIGLQVLEALKSLDDVAFVRYASVYRDFSHAEDFENVIAEINAKIARDTDAGA

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=45.578231292517, Blast_Score=126, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_AGRT5 (Q8UG74)

Other databases:

- EMBL:   AE007869
- PIR:   A97502
- PIR:   AE2720
- RefSeq:   NP_354185.1
- STRING:   Q8UG74
- GeneID:   1133204
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1166
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q8UG74
- ProtClustDB:   PRK00464
- BioCyc:   ATUM176299-1:ATU1166-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18182; Mature: 18182

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTYERVQLRELMVIKKSGRKLP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDREKLVRSFEIALRKRPVDRDRIERAVSGIARRLESSGETEIPSEEIGLQVLEALKSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
DVAFVRYASVYRDFSHAEDFENVIAEINAKIARDTDAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRCPFCGSEDTQVKDSRPAEDNTSIRRRRICPDCGGRFTTYERVQLRELMVIKKSGRKLP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDREKLVRSFEIALRKRPVDRDRIERAVSGIARRLESSGETEIPSEEIGLQVLEALKSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
DVAFVRYASVYRDFSHAEDFENVIAEINAKIARDTDAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194