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The map label for this gene is pgsA [H]

Identifier: 15888465

GI number: 15888465

Start: 1116733

End: 1117320

Strand: Reverse

Name: pgsA [H]

Synonym: Atu1128

Alternate gene names: 15888465

Gene position: 1117320-1116733 (Counterclockwise)

Preceding gene: 159184627

Following gene: 159184626

Centisome position: 39.32

GC content: 56.97

Gene sequence:

>588_bases
ATGGCTTCGCGCGCATACAACATTCCCAACCTCCTCACCTATGCCCGCATCCTTGCGGTTCCTGTCATCGTTTTGTGTTT
CTTTATCGAAGGAAAGCTGGAAAGCTCGGACTTCGCGCGCTGGACGGCACTCTGGCTGTTCATCGTCGCTTCGCTGACCG
ATTTTCTCGACGGTTATCTCGCCCGCATCTGGAACCAGACGTCGAATATCGGCCGCATGCTGGACCCGATAGCCGACAAG
CTGCTGGTCGCCTCCGTGCTGCTGTTGATGGCGGCGGATGGCACCATTGCCGGCTGGTCGCTCTGGGCTGCGATTACCAT
TCTCTGCCGTGAAATTCTGGTTTCCGGCCTGCGCGAATATCTAGCTGCGCTGAAGGTCAGCGTTCCCGTCACCCAGATCG
CCAAATGGAAGACAACCATCCAGATGGTTGCCATCGCCTTTCTTCTCGCAGGTCCTGCGGGCGACAAGGTGCTGCCCTAT
ACGACCGAGATGGGGATTACGCTTCTGTGGCTCGCCGCGGCGCTGACCATGTATACCGGTTATGATTACTTCAAGGCGGG
TCTCAAGCACATTGTGGACGAAGAATGA

Upstream 100 bases:

>100_bases
CAGAACGGTAAGACCGATCTGCTAAAAAACCATAATAACGTGTTGACCCTATGCGTCAGGGACGGCATCAAAGCAGCTTA
TCCAGACTGACAGGTTTTCC

Downstream 100 bases:

>100_bases
TGACGCGGATCGTTTATTTCGCCTGGGTTCGCGAGAAGATCGGCACGGATGAGGAAGAGCTGGATATCCCTTCCTCCGTC
ACCACCGCCGGCGAGCTGAT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MASRAYNIPNLLTYARILAVPVIVLCFFIEGKLESSDFARWTALWLFIVASLTDFLDGYLARIWNQTSNIGRMLDPIADK
LLVASVLLLMAADGTIAGWSLWAAITILCREILVSGLREYLAALKVSVPVTQIAKWKTTIQMVAIAFLLAGPAGDKVLPY
TTEMGITLLWLAAALTMYTGYDYFKAGLKHIVDEE

Sequences:

>Translated_195_residues
MASRAYNIPNLLTYARILAVPVIVLCFFIEGKLESSDFARWTALWLFIVASLTDFLDGYLARIWNQTSNIGRMLDPIADK
LLVASVLLLMAADGTIAGWSLWAAITILCREILVSGLREYLAALKVSVPVTQIAKWKTTIQMVAIAFLLAGPAGDKVLPY
TTEMGITLLWLAAALTMYTGYDYFKAGLKHIVDEE
>Mature_194_residues
ASRAYNIPNLLTYARILAVPVIVLCFFIEGKLESSDFARWTALWLFIVASLTDFLDGYLARIWNQTSNIGRMLDPIADKL
LVASVLLLMAADGTIAGWSLWAAITILCREILVSGLREYLAALKVSVPVTQIAKWKTTIQMVAIAFLLAGPAGDKVLPYT
TEMGITLLWLAAALTMYTGYDYFKAGLKHIVDEE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=191, Percent_Identity=39.7905759162304, Blast_Score=120, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6320059, Length=165, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21552; Mature: 21421

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRAYNIPNLLTYARILAVPVIVLCFFIEGKLESSDFARWTALWLFIVASLTDFLDGYL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARIWNQTSNIGRMLDPIADKLLVASVLLLMAADGTIAGWSLWAAITILCREILVSGLREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAALKVSVPVTQIAKWKTTIQMVAIAFLLAGPAGDKVLPYTTEMGITLLWLAAALTMYTG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
YDYFKAGLKHIVDEE
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASRAYNIPNLLTYARILAVPVIVLCFFIEGKLESSDFARWTALWLFIVASLTDFLDGYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARIWNQTSNIGRMLDPIADKLLVASVLLLMAADGTIAGWSLWAAITILCREILVSGLREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAALKVSVPVTQIAKWKTTIQMVAIAFLLAGPAGDKVLPYTTEMGITLLWLAAALTMYTG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
YDYFKAGLKHIVDEE
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA