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The map label for this gene is dnaC [H]

Identifier: 15888427

GI number: 15888427

Start: 1074674

End: 1076170

Strand: Reverse

Name: dnaC [H]

Synonym: Atu1084

Alternate gene names: 15888427

Gene position: 1076170-1074674 (Counterclockwise)

Preceding gene: 15888431

Following gene: 15888423

Centisome position: 37.87

GC content: 60.05

Gene sequence:

>1497_bases
ATGAACGACGCTGTGAGAAAGATCACCCCCGCGCAACCGGCGGAACCGCATTACCGCGAGGCGCCGAACAATATCGAGGC
CGAACAGGCGCTGCTTGGCGCCATCCTCGTCAACAACGACGCCTATTACCGCGTCTCGGACTTCTTGAAGCCCGTGCATC
TCTACGAGCCGCTGCATCGCAAGATTTTCGAGGTGGCGGGCGATATCATCCGCATGGGCAAGACCGCCAATCCGGTGACG
ATCAAGACCTTCCTGCCGGCAGATGACAAGATCGGCGACCTGACGGTGGCGCAATATCTCGCGCGCCTTGCGGCCGAAGC
CGTATCGATCATCAACGCGGAAGATTACGGTCGGGCGATCTATGATCTGGCGCTGCGCCGCGCGCTGATCCAGATCGGCG
AAGATGTCGTCAACATCGCCTATGACGCGCCGCTCGACATGCCGCCGCAGGCGCAGATTGAAGATACCGAGCGCCGCCTG
TTCGAACTGGCGGAAACCGGCCGCTACGACGGCGGTTTCCAGTCGTTCAACGATGCTGTGGCGCTGGCAATCGACATGGC
GGGCGCCGCTTTTGAGCGCGATGGCAACCTCTCCGGCATTTCCACCGGCATTCATTCGCTCGACGGCCGCATGGGCGGCC
TGCAGCGTTCCGACCTTATCGTGCTGGCTGGTCGTCCGGGTATGGGCAAGACCTCGCTTGCGACCAACATCGCCTATAAT
ATTGCCGCCTCCTATGAGCAGGAAGTGCAGCCGGACGGTTCTTTCAAGGCGAAGAATGGCGGCGTCGTCGGTTTCTATTC
GCTCGAAATGTCGTCCGAACAGCTGGCCACCCGTATCATTTCCGAGCAGACGGAAGTCTCCTCCTCGAAAATCCGCCGTG
GCGACATCACCGAGGCCGATTTCGAAAAGCTCATCGCCTGCTCCCAGATGATGCAGAAGGTGCCGCTTTATATCGACCAG
ACCGGTGGTATCTCCATCGCCCAGCTTTCCGCCCGTGCCCGCCGCCTGAAGCGCCAGCGCGGCCTCGATGTTCTGGTCGT
GGACTATATTCAGCTGATGACCGGCGCCGGCAAGAGCGGCGAAAACCGCGTGCAGGAAATCACCCAGATCACCACCGGCC
TCAAGGCACTGGGCAAGGAACTCAACGTCCCGATCATCGCGCTGTCACAGCTCTCCCGTGCGGTGGAAAACCGTGAAGAC
AAGCGCCCGCAGCTTTCAGACCTGCGTGAATCGGGCTCGATCGAGCAGGACGCCGACGTGGTTCTCTTCGTGTTCCGAGA
GGAATATTACGTCAAGAACATGGAACCGCGCGATATTTCCGATCCCAAATATGCCGAGTGGGAAGCGCTGTTCGACAAGG
TGAAAGGCACGGCCGACGTCATCATAGCCAAGCAGCGTCACGGACCGACCGGTACCGTGAAACTCGCCTTCCAGTCCGAA
TTCACACGCTTCGCCGATCTGGCCGATCCGAGCTTCACCCAGTACGAAGAGCACTGA

Upstream 100 bases:

>100_bases
CAGCCTGCCGTATAGTGTTGCAACAATATCATTGACTGCCATGCCCCAGGAAGCCAAACCCGAGGTTTAAGGACAAAGGC
AAAGGGAGATCGCGCAAACC

Downstream 100 bases:

>100_bases
TCCAAAACACAGCGAGGGTGACATATTTTCACCCCCGCTGCCCGCTTCGCATTACAGACGCCGAGTCCGGAGTCTTTTCA
GGACGTTGGCGCGATTTTCT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MNDAVRKITPAQPAEPHYREAPNNIEAEQALLGAILVNNDAYYRVSDFLKPVHLYEPLHRKIFEVAGDIIRMGKTANPVT
IKTFLPADDKIGDLTVAQYLARLAAEAVSIINAEDYGRAIYDLALRRALIQIGEDVVNIAYDAPLDMPPQAQIEDTERRL
FELAETGRYDGGFQSFNDAVALAIDMAGAAFERDGNLSGISTGIHSLDGRMGGLQRSDLIVLAGRPGMGKTSLATNIAYN
IAASYEQEVQPDGSFKAKNGGVVGFYSLEMSSEQLATRIISEQTEVSSSKIRRGDITEADFEKLIACSQMMQKVPLYIDQ
TGGISIAQLSARARRLKRQRGLDVLVVDYIQLMTGAGKSGENRVQEITQITTGLKALGKELNVPIIALSQLSRAVENRED
KRPQLSDLRESGSIEQDADVVLFVFREEYYVKNMEPRDISDPKYAEWEALFDKVKGTADVIIAKQRHGPTGTVKLAFQSE
FTRFADLADPSFTQYEEH

Sequences:

>Translated_498_residues
MNDAVRKITPAQPAEPHYREAPNNIEAEQALLGAILVNNDAYYRVSDFLKPVHLYEPLHRKIFEVAGDIIRMGKTANPVT
IKTFLPADDKIGDLTVAQYLARLAAEAVSIINAEDYGRAIYDLALRRALIQIGEDVVNIAYDAPLDMPPQAQIEDTERRL
FELAETGRYDGGFQSFNDAVALAIDMAGAAFERDGNLSGISTGIHSLDGRMGGLQRSDLIVLAGRPGMGKTSLATNIAYN
IAASYEQEVQPDGSFKAKNGGVVGFYSLEMSSEQLATRIISEQTEVSSSKIRRGDITEADFEKLIACSQMMQKVPLYIDQ
TGGISIAQLSARARRLKRQRGLDVLVVDYIQLMTGAGKSGENRVQEITQITTGLKALGKELNVPIIALSQLSRAVENRED
KRPQLSDLRESGSIEQDADVVLFVFREEYYVKNMEPRDISDPKYAEWEALFDKVKGTADVIIAKQRHGPTGTVKLAFQSE
FTRFADLADPSFTQYEEH
>Mature_498_residues
MNDAVRKITPAQPAEPHYREAPNNIEAEQALLGAILVNNDAYYRVSDFLKPVHLYEPLHRKIFEVAGDIIRMGKTANPVT
IKTFLPADDKIGDLTVAQYLARLAAEAVSIINAEDYGRAIYDLALRRALIQIGEDVVNIAYDAPLDMPPQAQIEDTERRL
FELAETGRYDGGFQSFNDAVALAIDMAGAAFERDGNLSGISTGIHSLDGRMGGLQRSDLIVLAGRPGMGKTSLATNIAYN
IAASYEQEVQPDGSFKAKNGGVVGFYSLEMSSEQLATRIISEQTEVSSSKIRRGDITEADFEKLIACSQMMQKVPLYIDQ
TGGISIAQLSARARRLKRQRGLDVLVVDYIQLMTGAGKSGENRVQEITQITTGLKALGKELNVPIIALSQLSRAVENRED
KRPQLSDLRESGSIEQDADVVLFVFREEYYVKNMEPRDISDPKYAEWEALFDKVKGTADVIIAKQRHGPTGTVKLAFQSE
FTRFADLADPSFTQYEEH

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=497, Percent_Identity=33.6016096579477, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 55017; Mature: 55017

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAVRKITPAQPAEPHYREAPNNIEAEQALLGAILVNNDAYYRVSDFLKPVHLYEPLHR
CCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHH
KIFEVAGDIIRMGKTANPVTIKTFLPADDKIGDLTVAQYLARLAAEAVSIINAEDYGRAI
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
YDLALRRALIQIGEDVVNIAYDAPLDMPPQAQIEDTERRLFELAETGRYDGGFQSFNDAV
HHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCE
ALAIDMAGAAFERDGNLSGISTGIHSLDGRMGGLQRSDLIVLAGRPGMGKTSLATNIAYN
EEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
IAASYEQEVQPDGSFKAKNGGVVGFYSLEMSSEQLATRIISEQTEVSSSKIRRGDITEAD
HHHHHHHHCCCCCCEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
FEKLIACSQMMQKVPLYIDQTGGISIAQLSARARRLKRQRGLDVLVVDYIQLMTGAGKSG
HHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
ENRVQEITQITTGLKALGKELNVPIIALSQLSRAVENREDKRPQLSDLRESGSIEQDADV
HHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCE
VLFVFREEYYVKNMEPRDISDPKYAEWEALFDKVKGTADVIIAKQRHGPTGTVKLAFQSE
EEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEHHH
FTRFADLADPSFTQYEEH
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNDAVRKITPAQPAEPHYREAPNNIEAEQALLGAILVNNDAYYRVSDFLKPVHLYEPLHR
CCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHH
KIFEVAGDIIRMGKTANPVTIKTFLPADDKIGDLTVAQYLARLAAEAVSIINAEDYGRAI
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
YDLALRRALIQIGEDVVNIAYDAPLDMPPQAQIEDTERRLFELAETGRYDGGFQSFNDAV
HHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCE
ALAIDMAGAAFERDGNLSGISTGIHSLDGRMGGLQRSDLIVLAGRPGMGKTSLATNIAYN
EEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
IAASYEQEVQPDGSFKAKNGGVVGFYSLEMSSEQLATRIISEQTEVSSSKIRRGDITEAD
HHHHHHHHCCCCCCEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
FEKLIACSQMMQKVPLYIDQTGGISIAQLSARARRLKRQRGLDVLVVDYIQLMTGAGKSG
HHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
ENRVQEITQITTGLKALGKELNVPIIALSQLSRAVENREDKRPQLSDLRESGSIEQDADV
HHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCE
VLFVFREEYYVKNMEPRDISDPKYAEWEALFDKVKGTADVIIAKQRHGPTGTVKLAFQSE
EEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEHHH
FTRFADLADPSFTQYEEH
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA