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The map label for this gene is bacA

Identifier: 15888341

GI number: 15888341

Start: 994197

End: 995033

Strand: Direct

Name: bacA

Synonym: Atu0998

Alternate gene names: 15888341

Gene position: 994197-995033 (Clockwise)

Preceding gene: 15888340

Following gene: 159184568

Centisome position: 34.99

GC content: 60.22

Gene sequence:

>837_bases
ATGAGCATGGGTTGGATGGAGGCCGGATTTCTCGGTCTATTGCAAGGACTTACGGAATTCCTTCCGGTTTCTTCAAGCGC
GCATCTCAGGATCGCCGGGGAGTTCCTGCCATCAGGCGCAGATCCAGGCGCCGCCTTCACCGCCATTACCCAGATCGGCA
CGGAAATGGCGGTGCTGGTCTATTTCTGGTCCGACATCATGCGGATTGCCGCCGCCTGGCTACGGCAGAACCTGCGCCTT
GGCGAATATAACAAGGCGGACGCCCGGCTCGGCTGGCTGATCATCGTCGGTTCGGTGCCGATCGTGTTTCTGGGGCTGTT
CTTCAAGGATGCGATCGAACATTCGCTGCGCAATCTTTATATCACCGCGGTGATGCTGATCGTCTTCGGCATCGTTCTTG
GTCTTGCCGACAGGATCGGTGAGAAGCGCTACAAGCTGAACCAGCTGATCTGGCGCGATGGCATCCTTTTCGGTTTCGCG
CAGGCGATGGCGCTCATTCCCGGCGTCTCGCGTTCAGGCGGCACCATCAGCGCCGGCCTGCTTCTGGGGTATACCCGTGA
GGCGGCGGCGCGGTATTCCTTCCTGCTCGCCGTTCCCGCCGTCTTCGGCTCCGGCTTCTACCAACTGTTCAAGAGCATCG
GCGAGGACAATCCGGTCGGCTGGGGCCAGACCGGGCTTGCGACCCTCATCGCCTTTATCGTCGGTTATGCCGTGATCGTC
GTGTTCCTGAAGCTGGTCTCGACCAAGAGCTACATGCCCTTCGTCTGGTACCGCGTGGTCATCGGCTTCATTCTGCTCGC
TCTGTTGGGAACAGGCGTCATCAGCGCCGGCGGCTGA

Upstream 100 bases:

>100_bases
GGTCGCGCGCGGGCCATTTTCATGGTGCGATGCAACACGGATTTGCCCCGATTGATGCATAATGCTGCAAACTCGATTCG
CAGCAGGGACATCAAAGCAC

Downstream 100 bases:

>100_bases
GGGCAGGGCCTCGCGCTTTTTCGGTCGCAAATGAAAAAGGCCCGCTCTTTCGAGCGGGCCTTTTGTCGTTAGAGCAACGT
GCCGCTCAAGATCACCAGCG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSMGWMEAGFLGLLQGLTEFLPVSSSAHLRIAGEFLPSGADPGAAFTAITQIGTEMAVLVYFWSDIMRIAAAWLRQNLRL
GEYNKADARLGWLIIVGSVPIVFLGLFFKDAIEHSLRNLYITAVMLIVFGIVLGLADRIGEKRYKLNQLIWRDGILFGFA
QAMALIPGVSRSGGTISAGLLLGYTREAAARYSFLLAVPAVFGSGFYQLFKSIGEDNPVGWGQTGLATLIAFIVGYAVIV
VFLKLVSTKSYMPFVWYRVVIGFILLALLGTGVISAGG

Sequences:

>Translated_278_residues
MSMGWMEAGFLGLLQGLTEFLPVSSSAHLRIAGEFLPSGADPGAAFTAITQIGTEMAVLVYFWSDIMRIAAAWLRQNLRL
GEYNKADARLGWLIIVGSVPIVFLGLFFKDAIEHSLRNLYITAVMLIVFGIVLGLADRIGEKRYKLNQLIWRDGILFGFA
QAMALIPGVSRSGGTISAGLLLGYTREAAARYSFLLAVPAVFGSGFYQLFKSIGEDNPVGWGQTGLATLIAFIVGYAVIV
VFLKLVSTKSYMPFVWYRVVIGFILLALLGTGVISAGG
>Mature_277_residues
SMGWMEAGFLGLLQGLTEFLPVSSSAHLRIAGEFLPSGADPGAAFTAITQIGTEMAVLVYFWSDIMRIAAAWLRQNLRLG
EYNKADARLGWLIIVGSVPIVFLGLFFKDAIEHSLRNLYITAVMLIVFGIVLGLADRIGEKRYKLNQLIWRDGILFGFAQ
AMALIPGVSRSGGTISAGLLLGYTREAAARYSFLLAVPAVFGSGFYQLFKSIGEDNPVGWGQTGLATLIAFIVGYAVIVV
FLKLVSTKSYMPFVWYRVVIGFILLALLGTGVISAGG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=258, Percent_Identity=36.046511627907, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_AGRT5 (P58741)

Other databases:

- EMBL:   AE007869
- PIR:   AF2699
- PIR:   F97481
- RefSeq:   NP_354022.1
- STRING:   P58741
- GeneID:   1133036
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0998
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- PhylomeDB:   P58741
- ProtClustDB:   PRK12554
- BioCyc:   ATUM176299-1:ATU0998-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30075; Mature: 29944

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xccffc50)-; HASH(0xde1cd30)-; HASH(0xe1c3adc)-; HASH(0xe1c3cbc)-; HASH(0xe1c3c44)-; HASH(0xd9f53b4)-; HASH(0xddf7240)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMGWMEAGFLGLLQGLTEFLPVSSSAHLRIAGEFLPSGADPGAAFTAITQIGTEMAVLV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHH
YFWSDIMRIAAAWLRQNLRLGEYNKADARLGWLIIVGSVPIVFLGLFFKDAIEHSLRNLY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHH
ITAVMLIVFGIVLGLADRIGEKRYKLNQLIWRDGILFGFAQAMALIPGVSRSGGTISAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHH
LLGYTREAAARYSFLLAVPAVFGSGFYQLFKSIGEDNPVGWGQTGLATLIAFIVGYAVIV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VFLKLVSTKSYMPFVWYRVVIGFILLALLGTGVISAGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCH
>Mature Secondary Structure 
SMGWMEAGFLGLLQGLTEFLPVSSSAHLRIAGEFLPSGADPGAAFTAITQIGTEMAVLV
CCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHH
YFWSDIMRIAAAWLRQNLRLGEYNKADARLGWLIIVGSVPIVFLGLFFKDAIEHSLRNLY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHH
ITAVMLIVFGIVLGLADRIGEKRYKLNQLIWRDGILFGFAQAMALIPGVSRSGGTISAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHH
LLGYTREAAARYSFLLAVPAVFGSGFYQLFKSIGEDNPVGWGQTGLATLIAFIVGYAVIV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VFLKLVSTKSYMPFVWYRVVIGFILLALLGTGVISAGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194