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The map label for this gene is cysW [H]

Identifier: 15888163

GI number: 15888163

Start: 820238

End: 821110

Strand: Direct

Name: cysW [H]

Synonym: Atu0822

Alternate gene names: 15888163

Gene position: 820238-821110 (Clockwise)

Preceding gene: 159184479

Following gene: 159184480

Centisome position: 28.87

GC content: 60.94

Gene sequence:

>873_bases
ATGTCTGAGACCGCTTCCCGCACCTCGCCCCGGCCATTCCGCGATCCCGCAAGCGAAAGCCTTCCCGCGCGGCTGGCGCT
GATCGCCGTTGCCTTCCTGTTCCTCGCGGCCTTCCTGGTGCTGCCGCTTGTCTCGGTCTTCTTCGAAGCCTTCCGCAAGG
GCGCGGATTCCTTCTGGGATGCCATCGTCGAACCAGATGCGCTGTCGGCCATCCGCCTGACGCTGCTCGTCGCCGCCATT
TCGGTGCCGCTCAACGTCGTTTTCGGGGTTGCCGCCGCCTGGGCGATCGCCAAATTCGAATTCAAGGGCAAGGCGTTCCT
GATCACCCTGATCGACCTGCCGTTCTCGATCTCGCCGGTCATATCGGGCCTCGTCTATGTCATCCTGTTTTCCGCTCACA
GCGTGCTCGGACCATGGTTGAAGAGTTACGGCATCGAAATCCTCTTTGCGGTCCCGGGCATCGTGCTGGCTACCATCTTC
GTCACCTTTCCCTTCGTCGCGCGCGAACTGATCCCGCTGATGCAGGATCAGGGCAATGGCGACGAGGAGGCGGCGATTTC
GCTTGGCGCATCCGGCTGGCAGACCTTCTGGTATGTGACGCTGCCCAATATCAAATGGGGCTTGCTTTACGGTGTGCTGC
TCTGCAACGCCCGCGCCATGGGCGAGTTCGGCGCCGTGTCCGTCGTATCAGGCCACATCCGCGGCGAGACCAACACCATG
CCGCTGCATGTCGAGATACTCTATAATGAGTACAATATCGGCGCATCTTTCGCCGTAGCGACACTGCTTGCAGGCCTCGC
GCTGGTGACGCTCGTTCTCAAAACCATTCTCGAAATACGCTTTGGCGCGGGCAACGCAGCCGGCAAGCATTGA

Upstream 100 bases:

>100_bases
GCGGCAGCCACCGGCATCGCCACCATCATGCTGATCATCTCGTTTGCCATGCTGTTCCTCATCAATCTCATTCAGGCCTG
GAGCCGCAAGAGGTACGGTT

Downstream 100 bases:

>100_bases
AAGGCATCTTCATGGAAGTGAAAGTTTCCGGCATCACCAAGCAGTTCGATCGGTTTCCGGCGCTGAACGACGTGTCGCTC
GATATACGCTCGGGCGAGCT

Product: ABC transporter, membrane spanning protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSETASRTSPRPFRDPASESLPARLALIAVAFLFLAAFLVLPLVSVFFEAFRKGADSFWDAIVEPDALSAIRLTLLVAAI
SVPLNVVFGVAAAWAIAKFEFKGKAFLITLIDLPFSISPVISGLVYVILFSAHSVLGPWLKSYGIEILFAVPGIVLATIF
VTFPFVARELIPLMQDQGNGDEEAAISLGASGWQTFWYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGETNTM
PLHVEILYNEYNIGASFAVATLLAGLALVTLVLKTILEIRFGAGNAAGKH

Sequences:

>Translated_290_residues
MSETASRTSPRPFRDPASESLPARLALIAVAFLFLAAFLVLPLVSVFFEAFRKGADSFWDAIVEPDALSAIRLTLLVAAI
SVPLNVVFGVAAAWAIAKFEFKGKAFLITLIDLPFSISPVISGLVYVILFSAHSVLGPWLKSYGIEILFAVPGIVLATIF
VTFPFVARELIPLMQDQGNGDEEAAISLGASGWQTFWYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGETNTM
PLHVEILYNEYNIGASFAVATLLAGLALVTLVLKTILEIRFGAGNAAGKH
>Mature_289_residues
SETASRTSPRPFRDPASESLPARLALIAVAFLFLAAFLVLPLVSVFFEAFRKGADSFWDAIVEPDALSAIRLTLLVAAIS
VPLNVVFGVAAAWAIAKFEFKGKAFLITLIDLPFSISPVISGLVYVILFSAHSVLGPWLKSYGIEILFAVPGIVLATIFV
TFPFVARELIPLMQDQGNGDEEAAISLGASGWQTFWYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGETNTMP
LHVEILYNEYNIGASFAVATLLAGLALVTLVLKTILEIRFGAGNAAGKH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=255, Percent_Identity=51.7647058823529, Blast_Score=274, Evalue=5e-75,
Organism=Escherichia coli, GI1788764, Length=226, Percent_Identity=34.9557522123894, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786980, Length=174, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31146; Mature: 31015

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETASRTSPRPFRDPASESLPARLALIAVAFLFLAAFLVLPLVSVFFEAFRKGADSFWD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AIVEPDALSAIRLTLLVAAISVPLNVVFGVAAAWAIAKFEFKGKAFLITLIDLPFSISPV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHH
ISGLVYVILFSAHSVLGPWLKSYGIEILFAVPGIVLATIFVTFPFVARELIPLMQDQGNG
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEEAAISLGASGWQTFWYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGETNTM
CCHHHEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCHHCCCCCCHHHEEEEECCCCCCC
PLHVEILYNEYNIGASFAVATLLAGLALVTLVLKTILEIRFGAGNAAGKH
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SETASRTSPRPFRDPASESLPARLALIAVAFLFLAAFLVLPLVSVFFEAFRKGADSFWD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
AIVEPDALSAIRLTLLVAAISVPLNVVFGVAAAWAIAKFEFKGKAFLITLIDLPFSISPV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHH
ISGLVYVILFSAHSVLGPWLKSYGIEILFAVPGIVLATIFVTFPFVARELIPLMQDQGNG
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEEAAISLGASGWQTFWYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGETNTM
CCHHHEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCHHCCCCCCHHHEEEEECCCCCCC
PLHVEILYNEYNIGASFAVATLLAGLALVTLVLKTILEIRFGAGNAAGKH
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]