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The map label for this gene is moaB [H]

Identifier: 15887972

GI number: 15887972

Start: 619257

End: 619826

Strand: Reverse

Name: moaB [H]

Synonym: Atu0631

Alternate gene names: 15887972

Gene position: 619826-619257 (Counterclockwise)

Preceding gene: 15887973

Following gene: 15887970

Centisome position: 21.81

GC content: 62.46

Gene sequence:

>570_bases
TTGAGGGCCGGATATTTCGAGGATAAGGCCATAGCAGGCGATAGACCCTTCATTCCCCTTGGCATTGCGGTTCTGACCGT
TTCGGACAGCCGCACGCTGGAGAACGACAAGTCCGGCGACACGCTCGTCGCAAGGCTGGAAGAAGCAGGCCACAGGCTCG
CCGCCCGCGCCATCGTGCCGGACGACAAGGCGGCGATCGCAGAGACGGTGCGCGAATGGACGCTGTCTGAAGGCGTGGAT
GTTGTCATCACCACCGGCGGCACCGGCTTTACCGGCCGCGACGTGACACCCGAGGCGCTGGAGCCGCTGTTCGAAAAGCG
CATGGACGGGTTTTCCGCGCTTTTCCATCGCATTTCCTATGACAAGATCGGCACCGCCACCATCCAGTCACGCGCGACCG
GCGGAGTGGCCAATGCCACCTTCATCTTCGTGCTGCCCGGCTCTCCCGGCGCCTGCAAGGATGCCTGGGATGGTATCCTC
AAGGCCCAGCTCGACTATCGCCACCTGCCCTGCAACTTCGTGGAAATCATGCCGCGGCTCGATGAGCATCTGAAGCGCGG
CAAAAGCTGA

Upstream 100 bases:

>100_bases
CCTGTTTCGGGATTTTTCATTCCTTCGATGCCGCCAAAAACGCGGAAACATCACTTAGGAAAAAACGTCCCGGCTGGTAT
TTTCACGCAACGCGGACCAT

Downstream 100 bases:

>100_bases
ATAGTCGCCTTGCCGCATGGGATGACCCACTCTTCTGCGCACTCATAAGCTCGGCGGTCGCTGACCGCCGAGCTTGACAT
CGTCACGGCGGTTAACGGCG

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MRAGYFEDKAIAGDRPFIPLGIAVLTVSDSRTLENDKSGDTLVARLEEAGHRLAARAIVPDDKAAIAETVREWTLSEGVD
VVITTGGTGFTGRDVTPEALEPLFEKRMDGFSALFHRISYDKIGTATIQSRATGGVANATFIFVLPGSPGACKDAWDGIL
KAQLDYRHLPCNFVEIMPRLDEHLKRGKS

Sequences:

>Translated_189_residues
MRAGYFEDKAIAGDRPFIPLGIAVLTVSDSRTLENDKSGDTLVARLEEAGHRLAARAIVPDDKAAIAETVREWTLSEGVD
VVITTGGTGFTGRDVTPEALEPLFEKRMDGFSALFHRISYDKIGTATIQSRATGGVANATFIFVLPGSPGACKDAWDGIL
KAQLDYRHLPCNFVEIMPRLDEHLKRGKS
>Mature_189_residues
MRAGYFEDKAIAGDRPFIPLGIAVLTVSDSRTLENDKSGDTLVARLEEAGHRLAARAIVPDDKAAIAETVREWTLSEGVD
VVITTGGTGFTGRDVTPEALEPLFEKRMDGFSALFHRISYDKIGTATIQSRATGGVANATFIFVLPGSPGACKDAWDGIL
KAQLDYRHLPCNFVEIMPRLDEHLKRGKS

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=36.3013698630137, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=36.3013698630137, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1787000, Length=157, Percent_Identity=50.3184713375796, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1786190, Length=106, Percent_Identity=35.8490566037736, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17564954, Length=145, Percent_Identity=37.2413793103448, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136978, Length=139, Percent_Identity=38.8489208633094, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24638841, Length=139, Percent_Identity=38.8489208633094, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 20519; Mature: 20519

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGYFEDKAIAGDRPFIPLGIAVLTVSDSRTLENDKSGDTLVARLEEAGHRLAARAIVP
CCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCC
DDKAAIAETVREWTLSEGVDVVITTGGTGFTGRDVTPEALEPLFEKRMDGFSALFHRISY
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DKIGTATIQSRATGGVANATFIFVLPGSPGACKDAWDGILKAQLDYRHLPCNFVEIMPRL
CCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DEHLKRGKS
HHHHHCCCC
>Mature Secondary Structure
MRAGYFEDKAIAGDRPFIPLGIAVLTVSDSRTLENDKSGDTLVARLEEAGHRLAARAIVP
CCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCC
DDKAAIAETVREWTLSEGVDVVITTGGTGFTGRDVTPEALEPLFEKRMDGFSALFHRISY
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DKIGTATIQSRATGGVANATFIFVLPGSPGACKDAWDGILKAQLDYRHLPCNFVEIMPRL
CCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DEHLKRGKS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]