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The map label for this gene is adhP [H]

Identifier: 15887967

GI number: 15887967

Start: 614537

End: 615565

Strand: Direct

Name: adhP [H]

Synonym: Atu0626

Alternate gene names: 15887967

Gene position: 614537-615565 (Clockwise)

Preceding gene: 15887966

Following gene: 159184395

Centisome position: 21.63

GC content: 61.61

Gene sequence:

>1029_bases
ATGACTAAAACAATGAAGGCGGCGGTTGTCCGCGCATTTGGAAAACCGCTGACCATCGAGGAAGTGGCAATACCGGATCC
CGGCCCCGGTGAAATTCTCATCAACTACAAGGCGACGGGCGTTTGCCACACCGACCTGCACGCCGCAACGGGGGATTGGC
CGGTCAAGCCCAACCCGCCCTTCATTCCCGGACATGAAGGTGCAGGTTACGTCGCCAAGATCGGCGCTGGCGTCACCGGC
ATCAAGGAGGGCGACCGCGCCGGCACGCCCTGGCTCTACACCGCCTGCGGATGCTGCATTCCCTGCCGTACCGGCTGGGA
AACCCTGTGCCCGAGCCAGAAGAACTCAGGTTATTCCGTCAACGGCAGCTTTGCCGAATATGGCCTTGCCGATCCGAAAT
TCGTCGGCCGCCTGCCTGACAATCTCGATTTCGGCCCAGCCGCACCCGTGCTCTGCGCCGGCGTTACAGTCTATAAGGGC
CTGAAGGAAACCGAAGTCAGGCCCGGTGAATGGGTGGTCATTTCAGGCATTGGCGGGCTTGGCCACATGGCCGTGCAATA
TGCGAAAGCCATGGGCATGCATGTGGTTGCCGCCGATATTTTCGACGACAAGCTGGCGCTTGCCAAAAAGCTCGGAGCCG
ACGTCGTCGTCAACGGCCGCGCGCCTGACGCGGTGGAGCAAGTGCAAAAGGCAACCGGCGGCGTCCATGGCGCGCTGGTG
ACGGCGGTTTCACCGAAGGCCATGGAGCAGGCTTATGGCTTCCTGCGCTCCAAGGGCACGATGGCGCTTGTCGGTCTGCC
GCCGGGCTTCATCTCCATTCCGGTGTTCGACACGGTGCTGAAGCGCATCACGGTGCGTGGCTCCATCGTCGGCACGCGGC
AGGATCTGGAGGAGGCGTTGACCTTCGCCGGTGAAGGCAAGGTGGCCGCCCACTTCTCGTGGGACAAGCTCGAAAACATC
AATGATATCTTCCATCGCATGGAAGAGGGCAAGATCGACGGCCGTATCGTCGTGGATCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
ATGCTTCGATTTGCGATGGGTCAATTCCATGACGCTCCATCCCCGTTAATCTCTGCCTGCCGTCGAGGATTTCAGGCGAG
CAGAGATTAGGGAGTATGTC

Downstream 100 bases:

>100_bases
CGTCAAACCCGGTTGCGGCGCTCACGCAAATGTGTGGCGCCGCTTCCGCCCGCCTTGTTCCGCGAAGGGCGATCTGCGTT
ATCCTCCTTTCGCATCCGGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTKTMKAAVVRAFGKPLTIEEVAIPDPGPGEILINYKATGVCHTDLHAATGDWPVKPNPPFIPGHEGAGYVAKIGAGVTG
IKEGDRAGTPWLYTACGCCIPCRTGWETLCPSQKNSGYSVNGSFAEYGLADPKFVGRLPDNLDFGPAAPVLCAGVTVYKG
LKETEVRPGEWVVISGIGGLGHMAVQYAKAMGMHVVAADIFDDKLALAKKLGADVVVNGRAPDAVEQVQKATGGVHGALV
TAVSPKAMEQAYGFLRSKGTMALVGLPPGFISIPVFDTVLKRITVRGSIVGTRQDLEEALTFAGEGKVAAHFSWDKLENI
NDIFHRMEEGKIDGRIVVDLAA

Sequences:

>Translated_342_residues
MTKTMKAAVVRAFGKPLTIEEVAIPDPGPGEILINYKATGVCHTDLHAATGDWPVKPNPPFIPGHEGAGYVAKIGAGVTG
IKEGDRAGTPWLYTACGCCIPCRTGWETLCPSQKNSGYSVNGSFAEYGLADPKFVGRLPDNLDFGPAAPVLCAGVTVYKG
LKETEVRPGEWVVISGIGGLGHMAVQYAKAMGMHVVAADIFDDKLALAKKLGADVVVNGRAPDAVEQVQKATGGVHGALV
TAVSPKAMEQAYGFLRSKGTMALVGLPPGFISIPVFDTVLKRITVRGSIVGTRQDLEEALTFAGEGKVAAHFSWDKLENI
NDIFHRMEEGKIDGRIVVDLAA
>Mature_341_residues
TKTMKAAVVRAFGKPLTIEEVAIPDPGPGEILINYKATGVCHTDLHAATGDWPVKPNPPFIPGHEGAGYVAKIGAGVTGI
KEGDRAGTPWLYTACGCCIPCRTGWETLCPSQKNSGYSVNGSFAEYGLADPKFVGRLPDNLDFGPAAPVLCAGVTVYKGL
KETEVRPGEWVVISGIGGLGHMAVQYAKAMGMHVVAADIFDDKLALAKKLGADVVVNGRAPDAVEQVQKATGGVHGALVT
AVSPKAMEQAYGFLRSKGTMALVGLPPGFISIPVFDTVLKRITVRGSIVGTRQDLEEALTFAGEGKVAAHFSWDKLENIN
DIFHRMEEGKIDGRIVVDLAA

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=361, Percent_Identity=28.808864265928, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI34577061, Length=361, Percent_Identity=28.808864265928, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI4501929, Length=361, Percent_Identity=29.3628808864266, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI156627571, Length=285, Percent_Identity=28.4210526315789, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI71565152, Length=366, Percent_Identity=27.0491803278689, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI71743840, Length=358, Percent_Identity=27.3743016759777, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI262073058, Length=358, Percent_Identity=27.3743016759777, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI194239674, Length=321, Percent_Identity=25.5451713395639, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI13236495, Length=321, Percent_Identity=25.5451713395639, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI71565154, Length=236, Percent_Identity=30.9322033898305, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI194239676, Length=232, Percent_Identity=27.1551724137931, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI156523966, Length=235, Percent_Identity=29.3617021276596, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4501939, Length=235, Percent_Identity=29.3617021276596, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI87081918, Length=337, Percent_Identity=46.2908011869436, Blast_Score=254, Evalue=4e-69,
Organism=Escherichia coli, GI1786518, Length=348, Percent_Identity=32.7586206896552, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI87082401, Length=324, Percent_Identity=32.4074074074074, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082125, Length=220, Percent_Identity=35.4545454545455, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788073, Length=282, Percent_Identity=31.2056737588652, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790045, Length=276, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788075, Length=319, Percent_Identity=28.8401253918495, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI226510992, Length=299, Percent_Identity=29.0969899665552, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790485, Length=286, Percent_Identity=29.7202797202797, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786552, Length=370, Percent_Identity=29.1891891891892, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787863, Length=209, Percent_Identity=30.1435406698565, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790718, Length=315, Percent_Identity=26.3492063492064, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788407, Length=254, Percent_Identity=29.5275590551181, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786825, Length=374, Percent_Identity=24.331550802139, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=342, Percent_Identity=40.6432748538012, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17562582, Length=347, Percent_Identity=41.4985590778098, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71988145, Length=342, Percent_Identity=36.5497076023392, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17562876, Length=334, Percent_Identity=32.3353293413174, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17562878, Length=334, Percent_Identity=32.3353293413174, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25146526, Length=248, Percent_Identity=30.6451612903226, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71997431, Length=250, Percent_Identity=30.4, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507255, Length=266, Percent_Identity=25.9398496240602, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=343, Percent_Identity=43.1486880466472, Blast_Score=270, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323961, Length=343, Percent_Identity=44.3148688046647, Blast_Score=266, Evalue=3e-72,
Organism=Saccharomyces cerevisiae, GI6319621, Length=343, Percent_Identity=41.9825072886297, Blast_Score=263, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6324486, Length=343, Percent_Identity=42.5655976676385, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6322619, Length=327, Percent_Identity=29.0519877675841, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319955, Length=327, Percent_Identity=29.0519877675841, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319949, Length=330, Percent_Identity=29.3939393939394, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6323099, Length=323, Percent_Identity=28.1733746130031, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323980, Length=332, Percent_Identity=28.3132530120482, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320033, Length=249, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17137530, Length=307, Percent_Identity=28.6644951140065, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17737897, Length=307, Percent_Identity=27.3615635179153, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17737895, Length=238, Percent_Identity=30.672268907563, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36039; Mature: 35908

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTMKAAVVRAFGKPLTIEEVAIPDPGPGEILINYKATGVCHTDLHAATGDWPVKPNPP
CCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECEEEECCCCCCCCCCCCCCCCC
FIPGHEGAGYVAKIGAGVTGIKEGDRAGTPWLYTACGCCIPCRTGWETLCPSQKNSGYSV
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHCCCCCCCCEEE
NGSFAEYGLADPKFVGRLPDNLDFGPAAPVLCAGVTVYKGLKETEVRPGEWVVISGIGGL
CCCHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCEEEEECCCCH
GHMAVQYAKAMGMHVVAADIFDDKLALAKKLGADVVVNGRAPDAVEQVQKATGGVHGALV
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
TAVSPKAMEQAYGFLRSKGTMALVGLPPGFISIPVFDTVLKRITVRGSIVGTRQDLEEAL
EECCHHHHHHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHHHCCEEEECHHHHHHHH
TFAGEGKVAAHFSWDKLENINDIFHRMEEGKIDGRIVVDLAA
HHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure 
TKTMKAAVVRAFGKPLTIEEVAIPDPGPGEILINYKATGVCHTDLHAATGDWPVKPNPP
CCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECEEEECCCCCCCCCCCCCCCCC
FIPGHEGAGYVAKIGAGVTGIKEGDRAGTPWLYTACGCCIPCRTGWETLCPSQKNSGYSV
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHCCCCCCCCEEE
NGSFAEYGLADPKFVGRLPDNLDFGPAAPVLCAGVTVYKGLKETEVRPGEWVVISGIGGL
CCCHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCEEEEECCCCH
GHMAVQYAKAMGMHVVAADIFDDKLALAKKLGADVVVNGRAPDAVEQVQKATGGVHGALV
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
TAVSPKAMEQAYGFLRSKGTMALVGLPPGFISIPVFDTVLKRITVRGSIVGTRQDLEEAL
EECCHHHHHHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHHHCCEEEECHHHHHHHH
TFAGEGKVAAHFSWDKLENINDIFHRMEEGKIDGRIVVDLAA
HHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9659380; 11481432 [H]