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The map label for this gene is murA

Identifier: 15887887

GI number: 15887887

Start: 529856

End: 531148

Strand: Reverse

Name: murA

Synonym: Atu0539

Alternate gene names: 15887887

Gene position: 531148-529856 (Counterclockwise)

Preceding gene: 15887888

Following gene: 159184360

Centisome position: 18.69

GC content: 63.26

Gene sequence:

>1293_bases
ATGGATCGCATCAGAATTACGGGTGGCAACAAGCTCAACGGCGTCATCCCCATCTCCGGCGCCAAAAACGCCGCCTTGCC
GTTGATGATCGCTTCGCTTCTGACCAGCGACACGCTGACGCTCGAAAACGTCCCGCATTTGGCTGACGTGGAGCAGCTCA
TCCGCATTCTCGGCAATCATGGCGTCGATATTTCCGTCAATGGTCGTCGCGAAAGCCAGGGCGAGGCCTATTCCCGCACC
GTACATTTCACCTGCCGTACCATTGTTGACACGACAGCCCCTTACGAGCTGGTCTCCAAGATGCGCGCGAGCTTCTGGGT
CATCGGCCCGCTTCTGGCGCGTGAGGGCCGCGCCCGCGTTTCCCTGCCCGGCGGCTGCGCCATCGGCACGCGCCCGGTCG
ACCTTTTCATCGAGGGCCTGCAGGCGCTTGGTGCGACGATGGAGATCGATGGCGGCTACATCAATGCCAGCGCCCCCAAG
GGTGGCCTCATCGGCGCTGTCTACACCTTCCCGAAAGTGTCAGTCGGCGCGACGCATGTGATGCTGATGGCAGCAAGCCT
TGCCCGCGGCACCACCGTCATCCACAACGCTGCCCGCGAGCCGGAAGTGGTCGATCTCGCGCACTGCCTGATCGCCATGG
GCGCCAAGATCGAAGGCGCCGGCACCTCCACCATCACCATTGAGGGCGTCACTTCGCTCTCCGGCGCGCGCCACCGGGTT
CTGCCCGATCGTATCGAAACCGGCACCTATGCCATGGCGGTCGCCATGGCCGGAGGTGACGTGGTGCTGGAAGGCACGCG
CGCATCGCTGCTCGACAATGCGCTCGACACGCTGCGGCTGGCAGGCGTCACGATCAGTGACACCGATACAGGACTGCGCG
TCGTGCGCAACGGCAACGGCATTCAACCGGTCGATATCGTCACCGAGCCCTTCCCCGGCTTCCCGACCGATCTGCAGGCG
CAGTTCATGGCGCTGATGACGCGTTCGCAGGGCGTCTCGCACATTACCGAGACCATCTTCGAAAACCGCTTCATGCATGT
GCAGGAACTGGCCCGTCTCGGCGCCAAAATTTCGCTCTCCGGCCAGATGGCTCGCATCGAAGGCGTTACCCGCCTCAAGG
GTGCGCCGGTCATGGCGACCGATCTGCGCGCCTCGGTGTCGCTGGTCATTGCGGGCCTCGTGGCAGAAGGCGAGACCATG
GTTTCGCGCGTCTATCACCTCGACCGCGGTTTCGAACGCCTCGAAGAAAAGCTTACCCGTTGCGGCGCACTGGTTGAACG
CGTCAGCGATTGA

Upstream 100 bases:

>100_bases
AATTCACCAGCATAAAATTGAAACGCCGCGGAAATTCGTCTAAGGACGCGTCTTTCCGCAAGGCATGATAAGAAAGGCGG
GCACAGGCCCGTAGGGACGC

Downstream 100 bases:

>100_bases
TACCTTCATTGCCGCTCTTCGATTTTCCACCCGTTGCACAGCGGGCCGCGACTGCTTATTTCCAGTACAAGAAATAGACA
TTGCGGCCCGTGTCCGCGGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDRIRITGGNKLNGVIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVEQLIRILGNHGVDISVNGRRESQGEAYSRT
VHFTCRTIVDTTAPYELVSKMRASFWVIGPLLAREGRARVSLPGGCAIGTRPVDLFIEGLQALGATMEIDGGYINASAPK
GGLIGAVYTFPKVSVGATHVMLMAASLARGTTVIHNAAREPEVVDLAHCLIAMGAKIEGAGTSTITIEGVTSLSGARHRV
LPDRIETGTYAMAVAMAGGDVVLEGTRASLLDNALDTLRLAGVTISDTDTGLRVVRNGNGIQPVDIVTEPFPGFPTDLQA
QFMALMTRSQGVSHITETIFENRFMHVQELARLGAKISLSGQMARIEGVTRLKGAPVMATDLRASVSLVIAGLVAEGETM
VSRVYHLDRGFERLEEKLTRCGALVERVSD

Sequences:

>Translated_430_residues
MDRIRITGGNKLNGVIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVEQLIRILGNHGVDISVNGRRESQGEAYSRT
VHFTCRTIVDTTAPYELVSKMRASFWVIGPLLAREGRARVSLPGGCAIGTRPVDLFIEGLQALGATMEIDGGYINASAPK
GGLIGAVYTFPKVSVGATHVMLMAASLARGTTVIHNAAREPEVVDLAHCLIAMGAKIEGAGTSTITIEGVTSLSGARHRV
LPDRIETGTYAMAVAMAGGDVVLEGTRASLLDNALDTLRLAGVTISDTDTGLRVVRNGNGIQPVDIVTEPFPGFPTDLQA
QFMALMTRSQGVSHITETIFENRFMHVQELARLGAKISLSGQMARIEGVTRLKGAPVMATDLRASVSLVIAGLVAEGETM
VSRVYHLDRGFERLEEKLTRCGALVERVSD
>Mature_430_residues
MDRIRITGGNKLNGVIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVEQLIRILGNHGVDISVNGRRESQGEAYSRT
VHFTCRTIVDTTAPYELVSKMRASFWVIGPLLAREGRARVSLPGGCAIGTRPVDLFIEGLQALGATMEIDGGYINASAPK
GGLIGAVYTFPKVSVGATHVMLMAASLARGTTVIHNAAREPEVVDLAHCLIAMGAKIEGAGTSTITIEGVTSLSGARHRV
LPDRIETGTYAMAVAMAGGDVVLEGTRASLLDNALDTLRLAGVTISDTDTGLRVVRNGNGIQPVDIVTEPFPGFPTDLQA
QFMALMTRSQGVSHITETIFENRFMHVQELARLGAKISLSGQMARIEGVTRLKGAPVMATDLRASVSLVIAGLVAEGETM
VSRVYHLDRGFERLEEKLTRCGALVERVSD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=49.6503496503497, Blast_Score=406, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_AGRT5 (Q8UHW9)

Other databases:

- EMBL:   AE007869
- PIR:   AG2642
- PIR:   H97424
- RefSeq:   NP_353568.1
- ProteinModelPortal:   Q8UHW9
- SMR:   Q8UHW9
- STRING:   Q8UHW9
- GeneID:   1132577
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0539
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q8UHW9
- ProtClustDB:   PRK09369
- BioCyc:   ATUM176299-1:ATU0539-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45658; Mature: 45658

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRITGGNKLNGVIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVEQLIRILGNH
CCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCC
GVDISVNGRRESQGEAYSRTVHFTCRTIVDTTAPYELVSKMRASFWVIGPLLAREGRARV
CEEEEECCCCCCCCCHHHEEEEEEEEEHHCCCCCHHHHHHHHHHHEEHHHHHHCCCCCEE
SLPGGCAIGTRPVDLFIEGLQALGATMEIDGGYINASAPKGGLIGAVYTFPKVSVGATHV
ECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCEEEEEECCCCCCCHHHH
MLMAASLARGTTVIHNAAREPEVVDLAHCLIAMGAKIEGAGTSTITIEGVTSLSGARHRV
HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCEEEEEEECCCCCCCCCCC
LPDRIETGTYAMAVAMAGGDVVLEGTRASLLDNALDTLRLAGVTISDTDTGLRVVRNGNG
CCCHHCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCC
IQPVDIVTEPFPGFPTDLQAQFMALMTRSQGVSHITETIFENRFMHVQELARLGAKISLS
CCCHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEC
GQMARIEGVTRLKGAPVMATDLRASVSLVIAGLVAEGETMVSRVYHLDRGFERLEEKLTR
CCCHHHCCHHHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
CGALVERVSD
HHHHHHHHCC
>Mature Secondary Structure
MDRIRITGGNKLNGVIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVEQLIRILGNH
CCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCC
GVDISVNGRRESQGEAYSRTVHFTCRTIVDTTAPYELVSKMRASFWVIGPLLAREGRARV
CEEEEECCCCCCCCCHHHEEEEEEEEEHHCCCCCHHHHHHHHHHHEEHHHHHHCCCCCEE
SLPGGCAIGTRPVDLFIEGLQALGATMEIDGGYINASAPKGGLIGAVYTFPKVSVGATHV
ECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEECCCCCCCCEEEEEECCCCCCCHHHH
MLMAASLARGTTVIHNAAREPEVVDLAHCLIAMGAKIEGAGTSTITIEGVTSLSGARHRV
HHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCEEEEEEECCCCCCCCCCC
LPDRIETGTYAMAVAMAGGDVVLEGTRASLLDNALDTLRLAGVTISDTDTGLRVVRNGNG
CCCHHCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCC
IQPVDIVTEPFPGFPTDLQAQFMALMTRSQGVSHITETIFENRFMHVQELARLGAKISLS
CCCHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEC
GQMARIEGVTRLKGAPVMATDLRASVSLVIAGLVAEGETMVSRVYHLDRGFERLEEKLTR
CCCHHHCCHHHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
CGALVERVSD
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194