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The map label for this gene is sppA [H]

Identifier: 15887687

GI number: 15887687

Start: 329164

End: 330117

Strand: Direct

Name: sppA [H]

Synonym: Atu0337

Alternate gene names: 15887687

Gene position: 329164-330117 (Clockwise)

Preceding gene: 15887680

Following gene: 15887688

Centisome position: 11.58

GC content: 57.65

Gene sequence:

>954_bases
ATGGATAATATGGCGATAGCTGATCGCAGGCGGTTGCGCCGCAAGCTGACTTTCTGGCGGGTTGCCGCCGTTCTCCTGCT
CGTCGTCGGCGCCTTCGGTCTTTACCGGTTTTTCTGGCAAGGCCCGCAGCAAAGCGCAAAACCCCATATCGCCCGCATCG
AGGTTTCCGGCCTGATCACCGACAATACCGAACTTCTCGAGCGGCTCGACAAGATCGCCAAGAGCGATAATGTCAAAGGC
CTGATCGTCTCGATTTCCTCACCCGGCGGCACCACCTACGGCGGGGAGCGCATCTTCAAGGTTATTCGAAGCGTCGCGGA
AAAGAAGCCGGTTGTCTCGGATGTACGCACGCTCGCCGCTTCCGCAGGTTATATGATCGCATCGGCAGGCGACGTCATCG
TTGCCGGCGAAACCTCTATCACCGGCTCGATCGGCGTGATCTTCCAGTACCCCCAGCTTGGCCAGCTGATGGAAAAACTC
GGCGTTTCGCTTCAGGAAATCAAGTCGTCACCGATGAAGGCGGAGCCTTCTCCTTTCCACGAAGCGCCGGAAGAGGCAAA
GACCATGATCCGCGCCATGGTGATGGACAGCTACGGCTGGTTCGTCGACCTCGTCGCCGATCGCCGCAAATTGCCGCGCG
AAGAGGTGTTGAAACTGGCTGATGGATCGATCTTCACTGGTCGGCAGGCGCTTGCCAACAAGCTGGTCGACACGCTCGGC
GGCGAAAAGGAAGTTCGCGCCTATTTCGAAACCCGTGGTGTGGCCAAGGATTTGCCGATCGTCGAATGGCGCGCGCCGTC
CTCCAATTCGCCTTTTGCGCTTTTCAGTGTTGCGCAAATAGCGAAACTTCTGGGATATGACGATTTAATTCCCTTCGCAG
GCCCCAGCCAGCTCGGTGCGGACAAGTTGTTTCTTGACGGTCTTGTTTCCGTTTGGCAGGTTGAGCCGCGTTAA

Upstream 100 bases:

>100_bases
CGAATTTTATCGTAATTCTGGTTTCTTTATTGTTTCCTTGCGGCTTCGCGTTAGAAGAACCATATGGCCTGAAACGCACG
GGCGGACGACAGAGGTTTCT

Downstream 100 bases:

>100_bases
AAATCCAATTCTTTCAGGGGGCAACCGTGATCAAGTCTGAACTGGTGCAGATCGTTGCTGCGCGTAACCCGCACCTTTAT
CACCGCGACGTGGAAAACAT

Product: proteinase IV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MDNMAIADRRRLRRKLTFWRVAAVLLLVVGAFGLYRFFWQGPQQSAKPHIARIEVSGLITDNTELLERLDKIAKSDNVKG
LIVSISSPGGTTYGGERIFKVIRSVAEKKPVVSDVRTLAASAGYMIASAGDVIVAGETSITGSIGVIFQYPQLGQLMEKL
GVSLQEIKSSPMKAEPSPFHEAPEEAKTMIRAMVMDSYGWFVDLVADRRKLPREEVLKLADGSIFTGRQALANKLVDTLG
GEKEVRAYFETRGVAKDLPIVEWRAPSSNSPFALFSVAQIAKLLGYDDLIPFAGPSQLGADKLFLDGLVSVWQVEPR

Sequences:

>Translated_317_residues
MDNMAIADRRRLRRKLTFWRVAAVLLLVVGAFGLYRFFWQGPQQSAKPHIARIEVSGLITDNTELLERLDKIAKSDNVKG
LIVSISSPGGTTYGGERIFKVIRSVAEKKPVVSDVRTLAASAGYMIASAGDVIVAGETSITGSIGVIFQYPQLGQLMEKL
GVSLQEIKSSPMKAEPSPFHEAPEEAKTMIRAMVMDSYGWFVDLVADRRKLPREEVLKLADGSIFTGRQALANKLVDTLG
GEKEVRAYFETRGVAKDLPIVEWRAPSSNSPFALFSVAQIAKLLGYDDLIPFAGPSQLGADKLFLDGLVSVWQVEPR
>Mature_317_residues
MDNMAIADRRRLRRKLTFWRVAAVLLLVVGAFGLYRFFWQGPQQSAKPHIARIEVSGLITDNTELLERLDKIAKSDNVKG
LIVSISSPGGTTYGGERIFKVIRSVAEKKPVVSDVRTLAASAGYMIASAGDVIVAGETSITGSIGVIFQYPQLGQLMEKL
GVSLQEIKSSPMKAEPSPFHEAPEEAKTMIRAMVMDSYGWFVDLVADRRKLPREEVLKLADGSIFTGRQALANKLVDTLG
GEKEVRAYFETRGVAKDLPIVEWRAPSSNSPFALFSVAQIAKLLGYDDLIPFAGPSQLGADKLFLDGLVSVWQVEPR

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=164, Percent_Identity=34.7560975609756, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787527, Length=166, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 34785; Mature: 34785

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNMAIADRRRLRRKLTFWRVAAVLLLVVGAFGLYRFFWQGPQQSAKPHIARIEVSGLIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEE
DNTELLERLDKIAKSDNVKGLIVSISSPGGTTYGGERIFKVIRSVAEKKPVVSDVRTLAA
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SAGYMIASAGDVIVAGETSITGSIGVIFQYPQLGQLMEKLGVSLQEIKSSPMKAEPSPFH
HCCEEEEECCCEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHCCCCCCCCCCCC
EAPEEAKTMIRAMVMDSYGWFVDLVADRRKLPREEVLKLADGSIFTGRQALANKLVDTLG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GEKEVRAYFETRGVAKDLPIVEWRAPSSNSPFALFSVAQIAKLLGYDDLIPFAGPSQLGA
CHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCH
DKLFLDGLVSVWQVEPR
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDNMAIADRRRLRRKLTFWRVAAVLLLVVGAFGLYRFFWQGPQQSAKPHIARIEVSGLIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEE
DNTELLERLDKIAKSDNVKGLIVSISSPGGTTYGGERIFKVIRSVAEKKPVVSDVRTLAA
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SAGYMIASAGDVIVAGETSITGSIGVIFQYPQLGQLMEKLGVSLQEIKSSPMKAEPSPFH
HCCEEEEECCCEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHCCCCCCCCCCCC
EAPEEAKTMIRAMVMDSYGWFVDLVADRRKLPREEVLKLADGSIFTGRQALANKLVDTLG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GEKEVRAYFETRGVAKDLPIVEWRAPSSNSPFALFSVAQIAKLLGYDDLIPFAGPSQLGA
CHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCH
DKLFLDGLVSVWQVEPR
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]