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The map label for this gene is ahpF [C]

Identifier: 15887588

GI number: 15887588

Start: 237803

End: 238696

Strand: Direct

Name: ahpF [C]

Synonym: Atu0238

Alternate gene names: 15887588

Gene position: 237803-238696 (Clockwise)

Preceding gene: 15887586

Following gene: 15887590

Centisome position: 8.37

GC content: 61.86

Gene sequence:

>894_bases
ATGAAATTCGACGTCATCATTATCGGCGGCAGCTATGCCGGCCTTTCCGCCGCCCTGCAGCTTGGTCGCGCCAGAAAAAA
CATCCTGCTCGTGGATGCCGGCGAACGCAGAAATCGTTTCGCCAGCCATTCACACGGTTTCCTCGGGCAAGATGGCAAGG
CGCCGGGCGAGATTATCGCCGAGGCACGCCGGCAGATCGAACGTTACCCGACCATACATTGGGTCGAAGGCAGGGTGACC
GACGCCAAGGGCTCTTTCGGTGAGTTCATCGTTGAGATCGACGGCGGCCGCCGGGAGACGGCGGGCCGGCTTATCCTCGC
CATGGGTGTGACCGATGAACTTCCTGAGATTGCCGGGCTGAGGGAGCGCTGGGGTTCTGCGGTCTTTCATTGCCCCTATT
GCCATGGCTATGAACTCGATCAGGGAAAAATCGGCGTCATCGCCGCTTCGCCAATGGCTATCCACCACGCGTTGATGCTT
CCCGACTGGGGCGAGACGACCTTTTTTACCAATGGCATAGTCGAGCCGGATGCGGATCAGCATGCGCTGCTGGCAGCGCG
CGGCGTCCGGGTAGAAACAACCCGCATCAGGGAGATTGCCGGGCATGCGGATGTCGTTCTGGCGGATGGCCGCAGCATCG
CACTGGCCGGGCTTTTCACCCAGCCGAAATTGCGCATCACTGTGGATTGGATCGAAAAACTCGGCTGCGCGGTGGAGGAA
GGGCCAATGGGATCGACCATCGTGACGGACCCGATGAAACAGACCACCGCCCGCGGCATCTTCGCGTGTGGCGATGTGGC
AAGACCGGCCGGCTCGGTCGCCCTTGCGGTGGGCGATGGCGCCATGGCGGGCGCTGCGGCTCACCGGTCCATCCTGTTCC
CGGAAATGCGCTAA

Upstream 100 bases:

>100_bases
TATAAGTTGCGTGACTATTGACTTCAAAATTCATGTAACAATATAAGTTTCATGAAAATGAACGGCGCTTCCGCCTCATT
CCCTGAACAATGGGTGCATC

Downstream 100 bases:

>100_bases
TGTGAGACGAGGCTCAGCCAACGGCCCGGGGGCATGCCGAAGGCATTTTTGAAATGCCGGGTGAAATGCGCCTGGTCCGC
GAAACCGCAGGCAAACGCCG

Product: oxidoreductase

Products: an alcohol; H2O; NAD [C]

Alternate protein names: Thioredoxin Reductase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Oxidoreductase; Thioredoxin-Disulfide Reductase; Reductase; Pyridine Nucleotide-Disulphide Oxidoreductase Class II; Pyridine Nucleotide-Disulphide Oxidoreductase; FAD Dependent Oxidoreductase; Thioredoxin Reductase Protein; Pyridine Nucleotide-Disulfide Oxidoreductase; Pyridine Nucleotide-Disulfide Oxidoreductase Domain Protein; Methyltransferase Type; Fad-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase; Pyridine Nucleotide-Disulfide Oxidoreductase Family Protein; Oxidoreductase Protein; Methyltransferase; Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase Large Subunit

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKFDVIIIGGSYAGLSAALQLGRARKNILLVDAGERRNRFASHSHGFLGQDGKAPGEIIAEARRQIERYPTIHWVEGRVT
DAKGSFGEFIVEIDGGRRETAGRLILAMGVTDELPEIAGLRERWGSAVFHCPYCHGYELDQGKIGVIAASPMAIHHALML
PDWGETTFFTNGIVEPDADQHALLAARGVRVETTRIREIAGHADVVLADGRSIALAGLFTQPKLRITVDWIEKLGCAVEE
GPMGSTIVTDPMKQTTARGIFACGDVARPAGSVALAVGDGAMAGAAAHRSILFPEMR

Sequences:

>Translated_297_residues
MKFDVIIIGGSYAGLSAALQLGRARKNILLVDAGERRNRFASHSHGFLGQDGKAPGEIIAEARRQIERYPTIHWVEGRVT
DAKGSFGEFIVEIDGGRRETAGRLILAMGVTDELPEIAGLRERWGSAVFHCPYCHGYELDQGKIGVIAASPMAIHHALML
PDWGETTFFTNGIVEPDADQHALLAARGVRVETTRIREIAGHADVVLADGRSIALAGLFTQPKLRITVDWIEKLGCAVEE
GPMGSTIVTDPMKQTTARGIFACGDVARPAGSVALAVGDGAMAGAAAHRSILFPEMR
>Mature_297_residues
MKFDVIIIGGSYAGLSAALQLGRARKNILLVDAGERRNRFASHSHGFLGQDGKAPGEIIAEARRQIERYPTIHWVEGRVT
DAKGSFGEFIVEIDGGRRETAGRLILAMGVTDELPEIAGLRERWGSAVFHCPYCHGYELDQGKIGVIAASPMAIHHALML
PDWGETTFFTNGIVEPDADQHALLAARGVRVETTRIREIAGHADVVLADGRSIALAGLFTQPKLRITVDWIEKLGCAVEE
GPMGSTIVTDPMKQTTARGIFACGDVARPAGSVALAVGDGAMAGAAAHRSILFPEMR

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.4.- [C]

Molecular weight: Translated: 31860; Mature: 31860

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDVIIIGGSYAGLSAALQLGRARKNILLVDAGERRNRFASHSHGFLGQDGKAPGEIIA
CEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHH
EARRQIERYPTIHWVEGRVTDAKGSFGEFIVEIDGGRRETAGRLILAMGVTDELPEIAGL
HHHHHHHHCCCEEEEECEEECCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHH
RERWGSAVFHCPYCHGYELDQGKIGVIAASPMAIHHALMLPDWGETTFFTNGIVEPDADQ
HHHHCCCEEECCCCCCEEECCCCEEEEEECCHHHEEEEECCCCCCCEEEECCCCCCCCCC
HALLAARGVRVETTRIREIAGHADVVLADGRSIALAGLFTQPKLRITVDWIEKLGCAVEE
CHHHHHCCCEEEHHHHHHHCCCCCEEEECCCEEEEEEEECCCEEEEEEEHHHHHCCEECC
GPMGSTIVTDPMKQTTARGIFACGDVARPAGSVALAVGDGAMAGAAAHRSILFPEMR
CCCCCEEEECCHHHHHHCCEEEECCCCCCCCCEEEEECCCCHHHHHHHCEECCCCCC
>Mature Secondary Structure
MKFDVIIIGGSYAGLSAALQLGRARKNILLVDAGERRNRFASHSHGFLGQDGKAPGEIIA
CEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHH
EARRQIERYPTIHWVEGRVTDAKGSFGEFIVEIDGGRRETAGRLILAMGVTDELPEIAGL
HHHHHHHHCCCEEEEECEEECCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHH
RERWGSAVFHCPYCHGYELDQGKIGVIAASPMAIHHALMLPDWGETTFFTNGIVEPDADQ
HHHHCCCEEECCCCCCEEECCCCEEEEEECCHHHEEEEECCCCCCCEEEECCCCCCCCCC
HALLAARGVRVETTRIREIAGHADVVLADGRSIALAGLFTQPKLRITVDWIEKLGCAVEE
CHHHHHCCCEEEHHHHHHHCCCCCEEEECCCEEEEEEEECCCEEEEEEEHHHHHCCEECC
GPMGSTIVTDPMKQTTARGIFACGDVARPAGSVALAVGDGAMAGAAAHRSILFPEMR
CCCCCEEEECCHHHHHHCCEEEECCCCCCCCCEEEEECCCCHHHHHHHCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ROOH; Proton; NADH [C]

Specific reaction: ROOH + Proton + NADH = an alcohol + H2O + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA