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The map label for this gene is cyoB [H]

Identifier: 15887496

GI number: 15887496

Start: 143594

End: 145597

Strand: Reverse

Name: cyoB [H]

Synonym: Atu0141

Alternate gene names: 15887496

Gene position: 145597-143594 (Counterclockwise)

Preceding gene: 159184178

Following gene: 15887495

Centisome position: 5.12

GC content: 58.38

Gene sequence:

>2004_bases
ATGATCGTCAATTCCGATCAAACGTCGTTCCTGTTCGGGAAGCTGACATGGGAATCCATCCCGCTTCACGAGCCCATTCT
TGTCGCCACCTTCGCGGCTGTGGCCCTGGGCGGCATCGTCGTCGTCGGCGCCCTCACCTACTTCCGCCTGTGGGGCTACC
TCTGGAATGAATGGTTCACGAGCATCGATCACAAGAAGATCGGTATCATGTACATCATTCTGGCGCTGGTCATGCTGCTG
CGCGGCTTTGCGGATGCCATCATGATGCGTGTCCAGCAGGCGATCGCGTCCGGCGGATCGGAGGGTTACCTTCCGCCGCA
TCACTACGACCAGATCTTCACGGCCCATGGCGTCATCATGATCTTTTTCATGGCCATGCCGATGATCACCGGCCTCATGA
ACTTCGTCGTGCCGCTGCAGATCGGCGCCCGCGACGTTTCGTTCCCCTTCCTCAACAACTTCTCCTTCTGGATGACCACG
GCTGGCGCCATCATCACCATGATCTCGCTGTTCGTGGGTGAATATGCGCAGACCGGCTGGCTCGCCTATCCGCCGCTGTC
CGGCATCGATGGCAGCCCTGGGGTCGGGGTCGATTATTACATTTGGGGTCTGCAGATCGCCGGTGTGGGAACGACGCTAT
CGGGCATCAACCTGATCGTGACCATCATCAAGATGCGCGCGCCTGGCATGACCATGATGCGCATGCCGATCTTCGTCTGG
ACGTCGCTGTGTTCTAACATCCTGATCGTCGCATCCTTCCCGATCCTGACTGCGACGCTCGCGCTTCTGACCCTTGACCG
CTACGCTGGTACGAATTTCTTCACCAACGATCTCGGCGGCAATCCGATGATGTATGTCAACCTCATCTGGATCTGGGGCC
ACCCCGAGGTTTACATTCTGGTGCTGCCGGCTTTCGGTATCTTCTCCGAAATCGTTGCCACCTTCTCGGGCAAGCGTCTG
TTCGGTTACGCGTCGATGGTTTACGCCACCGCCGTCATCACCATCCTCTCCTACCTCGTCTGGCTGCACCACTTCTTCAC
CATGGGTTCGGGCGCCAACGTCAATGCCTTCTTCGGCATCACCACGATGATCATCTCGATCCCCACGGGTGCGAAGATTT
TCAACTGGCTCTTCACCATGTATAAGGGCCGCATCAAGTTCGACGTGCCGATGCTGTGGACGATCGGCTTCATGATCACC
TTCGTCATCGGTGGCATGACCGGCGTTCTTCTCGCCGTTCCGCCGGCGGACTTCGTGCTGCACAACTCGCTGTTCCTGAT
CGCGCATTTCCACAACACGATCATCGGCGGCGTGGTCTTCGGCGTTCTGGCCGGTATCGTCTACTGGTTCCCGAAAGCCT
TCGGTTACCGTCTCGATCCGTTCTGGGGCAAGCTGTCCTTCTGGTTCTGGTTCATCGGCTTCTATTTCGCCTTCATGCCG
CTCTATATTCTCGGCCTGATGGGCATCACCCGCCGTATCAGCCAGTTCGAGGATAATTCACTGCAGATCTGGTTCGTGAT
TGCCGCCTTCGGCGCCTTCCTGATCGCGCTCGGCATCGCCTCCTTCATCATCCAGCTCATCGTCAGCTTCCTGAAGCGCG
ACCAGCTGCGTGACGTCACCGGCGATCCCTACAACGCCCGTACGCTGGAATGGTCGACATCGTCGCCACCGCCGCAGTAC
AACTTCGCCTTCACGCCGGTCATTCACGACGTGGATGCCTGGCATGATATGAAGAAGCGCGGCTACAGCCGTCCGCTGGA
CGGCTTCATTCCGATCCATATGCCGAAGAATACCGGTGCAGGCGTCATCATCAGCGCCATCAGCGTGGTGCTCGGCTTCG
CCCTGGTGTGGCACATCTGGTGGCTCGCCGCGCTGTCCTTCATCGGCGTCATCGCGGTCTCCATCGCCCACACCTTCAAC
TACAATCGCGATTATTACATTCCCGCGTCCGACGTTTCGACCGTCGAGGCGGAGCGTACGAAGCTGCTCGCGAAACAGGC
GTAA

Upstream 100 bases:

>100_bases
GAAACGAAACAAGTCGCTGGCTGACGGATACGTCCCGGCATTCTGCGGCGCGGCCAATGGCTGCGCCGATCTTACGTCTT
AGAATCGCAAGAGGCTGAAA

Downstream 100 bases:

>100_bases
CGGAACATGGCTCATACACCTGCACAAAGCGTCGACGGCGCTGAACCACCGGTCTTTTACCTGAAGGAAGACCACCACCC
GGAAAACGGCACTTCGATCG

Product: cytochrome O ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MIVNSDQTSFLFGKLTWESIPLHEPILVATFAAVALGGIVVVGALTYFRLWGYLWNEWFTSIDHKKIGIMYIILALVMLL
RGFADAIMMRVQQAIASGGSEGYLPPHHYDQIFTAHGVIMIFFMAMPMITGLMNFVVPLQIGARDVSFPFLNNFSFWMTT
AGAIITMISLFVGEYAQTGWLAYPPLSGIDGSPGVGVDYYIWGLQIAGVGTTLSGINLIVTIIKMRAPGMTMMRMPIFVW
TSLCSNILIVASFPILTATLALLTLDRYAGTNFFTNDLGGNPMMYVNLIWIWGHPEVYILVLPAFGIFSEIVATFSGKRL
FGYASMVYATAVITILSYLVWLHHFFTMGSGANVNAFFGITTMIISIPTGAKIFNWLFTMYKGRIKFDVPMLWTIGFMIT
FVIGGMTGVLLAVPPADFVLHNSLFLIAHFHNTIIGGVVFGVLAGIVYWFPKAFGYRLDPFWGKLSFWFWFIGFYFAFMP
LYILGLMGITRRISQFEDNSLQIWFVIAAFGAFLIALGIASFIIQLIVSFLKRDQLRDVTGDPYNARTLEWSTSSPPPQY
NFAFTPVIHDVDAWHDMKKRGYSRPLDGFIPIHMPKNTGAGVIISAISVVLGFALVWHIWWLAALSFIGVIAVSIAHTFN
YNRDYYIPASDVSTVEAERTKLLAKQA

Sequences:

>Translated_667_residues
MIVNSDQTSFLFGKLTWESIPLHEPILVATFAAVALGGIVVVGALTYFRLWGYLWNEWFTSIDHKKIGIMYIILALVMLL
RGFADAIMMRVQQAIASGGSEGYLPPHHYDQIFTAHGVIMIFFMAMPMITGLMNFVVPLQIGARDVSFPFLNNFSFWMTT
AGAIITMISLFVGEYAQTGWLAYPPLSGIDGSPGVGVDYYIWGLQIAGVGTTLSGINLIVTIIKMRAPGMTMMRMPIFVW
TSLCSNILIVASFPILTATLALLTLDRYAGTNFFTNDLGGNPMMYVNLIWIWGHPEVYILVLPAFGIFSEIVATFSGKRL
FGYASMVYATAVITILSYLVWLHHFFTMGSGANVNAFFGITTMIISIPTGAKIFNWLFTMYKGRIKFDVPMLWTIGFMIT
FVIGGMTGVLLAVPPADFVLHNSLFLIAHFHNTIIGGVVFGVLAGIVYWFPKAFGYRLDPFWGKLSFWFWFIGFYFAFMP
LYILGLMGITRRISQFEDNSLQIWFVIAAFGAFLIALGIASFIIQLIVSFLKRDQLRDVTGDPYNARTLEWSTSSPPPQY
NFAFTPVIHDVDAWHDMKKRGYSRPLDGFIPIHMPKNTGAGVIISAISVVLGFALVWHIWWLAALSFIGVIAVSIAHTFN
YNRDYYIPASDVSTVEAERTKLLAKQA
>Mature_667_residues
MIVNSDQTSFLFGKLTWESIPLHEPILVATFAAVALGGIVVVGALTYFRLWGYLWNEWFTSIDHKKIGIMYIILALVMLL
RGFADAIMMRVQQAIASGGSEGYLPPHHYDQIFTAHGVIMIFFMAMPMITGLMNFVVPLQIGARDVSFPFLNNFSFWMTT
AGAIITMISLFVGEYAQTGWLAYPPLSGIDGSPGVGVDYYIWGLQIAGVGTTLSGINLIVTIIKMRAPGMTMMRMPIFVW
TSLCSNILIVASFPILTATLALLTLDRYAGTNFFTNDLGGNPMMYVNLIWIWGHPEVYILVLPAFGIFSEIVATFSGKRL
FGYASMVYATAVITILSYLVWLHHFFTMGSGANVNAFFGITTMIISIPTGAKIFNWLFTMYKGRIKFDVPMLWTIGFMIT
FVIGGMTGVLLAVPPADFVLHNSLFLIAHFHNTIIGGVVFGVLAGIVYWFPKAFGYRLDPFWGKLSFWFWFIGFYFAFMP
LYILGLMGITRRISQFEDNSLQIWFVIAAFGAFLIALGIASFIIQLIVSFLKRDQLRDVTGDPYNARTLEWSTSSPPPQY
NFAFTPVIHDVDAWHDMKKRGYSRPLDGFIPIHMPKNTGAGVIISAISVVLGFALVWHIWWLAALSFIGVIAVSIAHTFN
YNRDYYIPASDVSTVEAERTKLLAKQA

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=40.1174168297456, Blast_Score=356, Evalue=4e-98,
Organism=Escherichia coli, GI1786634, Length=657, Percent_Identity=67.427701674277, Blast_Score=933, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=504, Percent_Identity=38.8888888888889, Blast_Score=349, Evalue=8e-97,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=43.4250764525994, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=36.4372469635627, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74483; Mature: 74483

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVNSDQTSFLFGKLTWESIPLHEPILVATFAAVALGGIVVVGALTYFRLWGYLWNEWFT
CCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIDHKKIGIMYIILALVMLLRGFADAIMMRVQQAIASGGSEGYLPPHHYDQIFTAHGVIM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IFFMAMPMITGLMNFVVPLQIGARDVSFPFLNNFSFWMTTAGAIITMISLFVGEYAQTGW
HHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LAYPPLSGIDGSPGVGVDYYIWGLQIAGVGTTLSGINLIVTIIKMRAPGMTMMRMPIFVW
EECCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TSLCSNILIVASFPILTATLALLTLDRYAGTNFFTNDLGGNPMMYVNLIWIWGHPEVYIL
HHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEE
VLPAFGIFSEIVATFSGKRLFGYASMVYATAVITILSYLVWLHHFFTMGSGANVNAFFGI
EECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
TTMIISIPTGAKIFNWLFTMYKGRIKFDVPMLWTIGFMITFVIGGMTGVLLAVPPADFVL
HHHEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHH
HNSLFLIAHFHNTIIGGVVFGVLAGIVYWFPKAFGYRLDPFWGKLSFWFWFIGFYFAFMP
HCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LYILGLMGITRRISQFEDNSLQIWFVIAAFGAFLIALGIASFIIQLIVSFLKRDQLRDVT
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDPYNARTLEWSTSSPPPQYNFAFTPVIHDVDAWHDMKKRGYSRPLDGFIPIHMPKNTGA
CCCCCCEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCC
GVIISAISVVLGFALVWHIWWLAALSFIGVIAVSIAHTFNYNRDYYIPASDVSTVEAERT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
KLLAKQA
HHHHCCC
>Mature Secondary Structure
MIVNSDQTSFLFGKLTWESIPLHEPILVATFAAVALGGIVVVGALTYFRLWGYLWNEWFT
CCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIDHKKIGIMYIILALVMLLRGFADAIMMRVQQAIASGGSEGYLPPHHYDQIFTAHGVIM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IFFMAMPMITGLMNFVVPLQIGARDVSFPFLNNFSFWMTTAGAIITMISLFVGEYAQTGW
HHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LAYPPLSGIDGSPGVGVDYYIWGLQIAGVGTTLSGINLIVTIIKMRAPGMTMMRMPIFVW
EECCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TSLCSNILIVASFPILTATLALLTLDRYAGTNFFTNDLGGNPMMYVNLIWIWGHPEVYIL
HHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEE
VLPAFGIFSEIVATFSGKRLFGYASMVYATAVITILSYLVWLHHFFTMGSGANVNAFFGI
EECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
TTMIISIPTGAKIFNWLFTMYKGRIKFDVPMLWTIGFMITFVIGGMTGVLLAVPPADFVL
HHHEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHCEEEECCCHHHHH
HNSLFLIAHFHNTIIGGVVFGVLAGIVYWFPKAFGYRLDPFWGKLSFWFWFIGFYFAFMP
HCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LYILGLMGITRRISQFEDNSLQIWFVIAAFGAFLIALGIASFIIQLIVSFLKRDQLRDVT
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDPYNARTLEWSTSSPPPQYNFAFTPVIHDVDAWHDMKKRGYSRPLDGFIPIHMPKNTGA
CCCCCCEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCC
GVIISAISVVLGFALVWHIWWLAALSFIGVIAVSIAHTFNYNRDYYIPASDVSTVEAERT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
KLLAKQA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]