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The map label for this gene is dnaX [H]

Identifier: 15887450

GI number: 15887450

Start: 99494

End: 101368

Strand: Reverse

Name: dnaX [H]

Synonym: Atu0096

Alternate gene names: 15887450

Gene position: 101368-99494 (Counterclockwise)

Preceding gene: 15887453

Following gene: 15887449

Centisome position: 3.57

GC content: 62.99

Gene sequence:

>1875_bases
ATGAGCGATACCGTACCCCCCAAATCAAGCGAATCCCAGGTCGGGACCGGCTACCGGGTACTGGCGCGCAAATATCGCCC
GAAGGATTTCTCCGATCTGATGGTCGGCCAGGAGCCGATGGTTCGAACGCTGACCAACGCGTTTGAGACCGGCCGCATCG
CGCAGGCCTATATGCTGACCGGCGTTCGCGGCGTGGGCAAGACGACCACGGCCCGCATTCTCGCCCGCGCACTGAATTAC
AAGACCGACACCATCGACAAACCGACCATCGACCTTCGTATTCCCGGCGAACATTGCCAGGCGATCATGGAAGGCCGGCA
TGTCGACGTGATCGAGATGGACGCCGCATCCCATACCGGCATCGACGATATTCGTGAGATCATCGAGCAGGTGCGCTATC
GCCCGGTCTCGGCGCGCTACAAGGTCTATATCATCGACGAAGTGCACATGCTGTCGACGCAGGCTTTCAACGGTCTTCTG
AAGACCCTGGAAGAGCCGCCGGAGCATGTGAAATTCATCTTCGCGACCACCGAAATCCGCAAGGTGCCGATTACCGTTCT
GTCGCGCTGCCAGCGTTTCGACCTGCGCCGCATCAGCGCCGCCGATCTTGTCGGCCTGTTCACCGCCATTGCCGGCAAGG
AAGGTTTCGAAGCCGAGCCGCAGGCGCTGTCAATGATCGCCCGCGCAGCCGAGGGTTCCGCCCGTGACGGTCTTTCCCTG
CTCGACCAGGCGATTGCCCATGGCGGCGGCCGTGTGGAGGCCGAAGCGGTGCGCGGCATGCTCGGCCTTGCCGACCGTGC
GCGCATTGTCGATCTCTTCCAGCATGTCGTCAAAGGCGATGTGGCGGCTGCCCTTTCGGAATTCAACGGACAATATGAGG
CTGGCGCAAACCCGGTTGTCGTTTTGAACGACCTCGCCGATTTCACCCATCTCGTCACCCGCATGAAATACGTTCCCGAC
GCAGCGGAAGACCCCTCGCTTTCCGAAATCGAGCGCACGCGCGGCGCGGAGTTTGCCGAAACCATCGCTGTAACGGCGCT
GTCACGCATCTGGCAAATGCTGCTGAAGGGCATTCCGGAAACGGAAAACGCTTCGCGCCCGGCGGGTGCCGCTGAAATGG
TGCTGATCCGGCTTTCGCATGCCGCCAATCTGCCGGCACCGGAAGATGCGGCGCGGCGCCTGCTGGAGCTTTCCAGCGCT
GACGGCAGTTACACCAATGGCGGACCTTCCGGCGGCGGCAACGGCGGTGGCGCGCGCGCCTATTCGTCGGCGCAGACCGT
GGCAGCGGCAAGACCTGCAGAATTTGCCGCCCCGAGGCAGGCCGGTCCGCAGCCCTCCACCATGCTGCGCGCCGTTCCAG
ACAGCCGGCCGCAGGAGATGCAGGTCGCGGCCCCGAAAACCGAAGAACGGCCGGAGCCGAAGGTTCCCGTCAATTCGCTG
CAGGATATTGCCGATCTCTGCCAGAAAAACCGTGATCCTGTCATGCGGGCGAAGGTGCGCAACTTCGTGCGGCTGGTTCG
GCTGGAGCCCGGCCGCCTTGATATGCGCCTCGGCGAAGGCGCCCCCGGCTCGCTGCCCGGTGAGCTTGGCGTCAAGCTGA
AGGAATGGACCGGTATCCACTGGATCGTCAGCCTCAGCAAGGAACAGGGCGAGCCGACCTTGGTCGAGGCGGAAGGCAAT
GCCCGCGATGCCCGCCTGGTCGACGCGCGTCAGGATCCTGATGTTGCCGCGATCCTGGCGCAGTTTCCCGGCGCAAAAAT
CACCGACGTACGTATTCGCGCGGCGATACAGGATGAGGCGGAGGATATCACCCCGCCATCGGTTGCCGAATCGAGCGAAG
GCGACATCCTTCCCGGCGACGACATCGAGTTTTAA

Upstream 100 bases:

>100_bases
GTCGCCGTGCCAGCCTCCCACCTTTTTTAAAAGACGTGCTCAGCTTTCGCCGGGCCAGTTCCGCGCCCCGAGACAACTGG
CAAAACAAACTGGCGAGGCA

Downstream 100 bases:

>100_bases
ACAAGAAGAACAGGAGATTGGCACATGCGCGACATCATGGGTATGATGGGCAAGGTCAAGGAAATGCAGTCCAAGATGGA
GAAGGTGCAGCAGGAAATTG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MSDTVPPKSSESQVGTGYRVLARKYRPKDFSDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNY
KTDTIDKPTIDLRIPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLL
KTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISAADLVGLFTAIAGKEGFEAEPQALSMIARAAEGSARDGLSL
LDQAIAHGGGRVEAEAVRGMLGLADRARIVDLFQHVVKGDVAAALSEFNGQYEAGANPVVVLNDLADFTHLVTRMKYVPD
AAEDPSLSEIERTRGAEFAETIAVTALSRIWQMLLKGIPETENASRPAGAAEMVLIRLSHAANLPAPEDAARRLLELSSA
DGSYTNGGPSGGGNGGGARAYSSAQTVAAARPAEFAAPRQAGPQPSTMLRAVPDSRPQEMQVAAPKTEERPEPKVPVNSL
QDIADLCQKNRDPVMRAKVRNFVRLVRLEPGRLDMRLGEGAPGSLPGELGVKLKEWTGIHWIVSLSKEQGEPTLVEAEGN
ARDARLVDARQDPDVAAILAQFPGAKITDVRIRAAIQDEAEDITPPSVAESSEGDILPGDDIEF

Sequences:

>Translated_624_residues
MSDTVPPKSSESQVGTGYRVLARKYRPKDFSDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNY
KTDTIDKPTIDLRIPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLL
KTLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISAADLVGLFTAIAGKEGFEAEPQALSMIARAAEGSARDGLSL
LDQAIAHGGGRVEAEAVRGMLGLADRARIVDLFQHVVKGDVAAALSEFNGQYEAGANPVVVLNDLADFTHLVTRMKYVPD
AAEDPSLSEIERTRGAEFAETIAVTALSRIWQMLLKGIPETENASRPAGAAEMVLIRLSHAANLPAPEDAARRLLELSSA
DGSYTNGGPSGGGNGGGARAYSSAQTVAAARPAEFAAPRQAGPQPSTMLRAVPDSRPQEMQVAAPKTEERPEPKVPVNSL
QDIADLCQKNRDPVMRAKVRNFVRLVRLEPGRLDMRLGEGAPGSLPGELGVKLKEWTGIHWIVSLSKEQGEPTLVEAEGN
ARDARLVDARQDPDVAAILAQFPGAKITDVRIRAAIQDEAEDITPPSVAESSEGDILPGDDIEF
>Mature_623_residues
SDTVPPKSSESQVGTGYRVLARKYRPKDFSDLMVGQEPMVRTLTNAFETGRIAQAYMLTGVRGVGKTTTARILARALNYK
TDTIDKPTIDLRIPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLK
TLEEPPEHVKFIFATTEIRKVPITVLSRCQRFDLRRISAADLVGLFTAIAGKEGFEAEPQALSMIARAAEGSARDGLSLL
DQAIAHGGGRVEAEAVRGMLGLADRARIVDLFQHVVKGDVAAALSEFNGQYEAGANPVVVLNDLADFTHLVTRMKYVPDA
AEDPSLSEIERTRGAEFAETIAVTALSRIWQMLLKGIPETENASRPAGAAEMVLIRLSHAANLPAPEDAARRLLELSSAD
GSYTNGGPSGGGNGGGARAYSSAQTVAAARPAEFAAPRQAGPQPSTMLRAVPDSRPQEMQVAAPKTEERPEPKVPVNSLQ
DIADLCQKNRDPVMRAKVRNFVRLVRLEPGRLDMRLGEGAPGSLPGELGVKLKEWTGIHWIVSLSKEQGEPTLVEAEGNA
RDARLVDARQDPDVAAILAQFPGAKITDVRIRAAIQDEAEDITPPSVAESSEGDILPGDDIEF

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=373, Percent_Identity=42.0911528150134, Blast_Score=275, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6322528, Length=303, Percent_Identity=21.7821782178218, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324478, Length=239, Percent_Identity=25.9414225941423, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17647857, Length=281, Percent_Identity=26.6903914590747, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 67552; Mature: 67421

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTVPPKSSESQVGTGYRVLARKYRPKDFSDLMVGQEPMVRTLTNAFETGRIAQAYMLT
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHH
GVRGVGKTTTARILARALNYKTDTIDKPTIDLRIPGEHCQAIMEGRHVDVIEMDAASHTG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHCCCCCEEEEECCCCCCC
IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR
HHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHH
KVPITVLSRCQRFDLRRISAADLVGLFTAIAGKEGFEAEPQALSMIARAAEGSARDGLSL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHH
LDQAIAHGGGRVEAEAVRGMLGLADRARIVDLFQHVVKGDVAAALSEFNGQYEAGANPVV
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
VLNDLADFTHLVTRMKYVPDAAEDPSLSEIERTRGAEFAETIAVTALSRIWQMLLKGIPE
EEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
TENASRPAGAAEMVLIRLSHAANLPAPEDAARRLLELSSADGSYTNGGPSGGGNGGGARA
CCCCCCCCCHHHHHEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
YSSAQTVAAARPAEFAAPRQAGPQPSTMLRAVPDSRPQEMQVAAPKTEERPEPKVPVNSL
HHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHH
QDIADLCQKNRDPVMRAKVRNFVRLVRLEPGRLDMRLGEGAPGSLPGELGVKLKEWTGIH
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCEEHHCCCEE
WIVSLSKEQGEPTLVEAEGNARDARLVDARQDPDVAAILAQFPGAKITDVRIRAAIQDEA
EEEEECCCCCCCEEEECCCCCCCCEEECCCCCCCHHHHHHHCCCCCEEEEEEEEHHHHHH
EDITPPSVAESSEGDILPGDDIEF
HCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDTVPPKSSESQVGTGYRVLARKYRPKDFSDLMVGQEPMVRTLTNAFETGRIAQAYMLT
CCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHH
GVRGVGKTTTARILARALNYKTDTIDKPTIDLRIPGEHCQAIMEGRHVDVIEMDAASHTG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHCCCCCEEEEECCCCCCC
IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR
HHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHH
KVPITVLSRCQRFDLRRISAADLVGLFTAIAGKEGFEAEPQALSMIARAAEGSARDGLSL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHH
LDQAIAHGGGRVEAEAVRGMLGLADRARIVDLFQHVVKGDVAAALSEFNGQYEAGANPVV
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
VLNDLADFTHLVTRMKYVPDAAEDPSLSEIERTRGAEFAETIAVTALSRIWQMLLKGIPE
EEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
TENASRPAGAAEMVLIRLSHAANLPAPEDAARRLLELSSADGSYTNGGPSGGGNGGGARA
CCCCCCCCCHHHHHEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
YSSAQTVAAARPAEFAAPRQAGPQPSTMLRAVPDSRPQEMQVAAPKTEERPEPKVPVNSL
HHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCHHHH
QDIADLCQKNRDPVMRAKVRNFVRLVRLEPGRLDMRLGEGAPGSLPGELGVKLKEWTGIH
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCEEHHCCCEE
WIVSLSKEQGEPTLVEAEGNARDARLVDARQDPDVAAILAQFPGAKITDVRIRAAIQDEA
EEEEECCCCCCCEEEECCCCCCCCEEECCCCCCCHHHHHHHCCCCCEEEEEEEEHHHHHH
EDITPPSVAESSEGDILPGDDIEF
HCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]