| Definition | Azorhizobium caulinodans ORS 571, complete genome. |
|---|---|
| Accession | NC_009937 |
| Length | 5,369,772 |
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The map label for this gene is ppi [H]
Identifier: 158423949
GI number: 158423949
Start: 2648411
End: 2648995
Strand: Reverse
Name: ppi [H]
Synonym: AZC_2325
Alternate gene names: 158423949
Gene position: 2648995-2648411 (Counterclockwise)
Preceding gene: 158423950
Following gene: 158423948
Centisome position: 49.33
GC content: 64.62
Gene sequence:
>585_bases GTGATGTCCCGTCTCATCGGCCGCCGTGAATTCACTGGCCTTGCCTTCGCCACGGCCTTCGCCGCCCCGGCCATGGCCCA GACCGCCAAGCCTGCGCCGAAGAGCGATCCGCAGAACACGCTCTATCTCGACACGGCCTATGGCCGCGTGGTGATCGCGC TGCGTCCCGATCTCGCGCCCGCCCATGTGGAGCGCCTCAAGACGCTCACCCGCGAGGGCTATTACAACAACGCGCCGTTC CACCGCGTCATCGACGGCTTCATGGCCCAGACGGGCGATGGCCAGTATGGCAACGGCACCGGAGGTTCGAAGTATCCGAA CCTTAAGGCCGAGTTCAGCAACACCCCGTTCGTGCGCGGCACGGTGGGCATGGCCCGCGCCTCCTCGCCGGACAGCGCCA ATTCCCAGTTCTTCATCTGCTATGCGGATTCCTCCTTCCTGAACGGCCAGTACACGGTGGTCGGGCAGGTGGTCTCCGGC ATGGAGTTCATCGACAAGCTGAAGAAGGGCCCGAAGGAAGCCAATGGCGCGGTGCCCAATCCCGACCGCATCGTGAAGAT GCAGGTCGCGGCCGACGTGAAGTGA
Upstream 100 bases:
>100_bases CGCGCCTGAAGGCCAAGTTCCCCTCCGCGTCCTGACCGGACGACCCGCCATTCACCCGCCGTCTCACGGGCGAAGACCCG CCGGCGATCCAAGGAGCCTT
Downstream 100 bases:
>100_bases TCCATTCCAACAATCATCAGGAGAGGCCCAATGGCTGAAGAACTGCTCGTCCTCGAAACCACCAAGGGCGACGTGACCAT CAAGTTCCGCCCCGATCTCG
Product: eptidyl-prolyl cis-trans isomerase
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 194; Mature: 194
Protein sequence:
>194_residues MMSRLIGRREFTGLAFATAFAAPAMAQTAKPAPKSDPQNTLYLDTAYGRVVIALRPDLAPAHVERLKTLTREGYYNNAPF HRVIDGFMAQTGDGQYGNGTGGSKYPNLKAEFSNTPFVRGTVGMARASSPDSANSQFFICYADSSFLNGQYTVVGQVVSG MEFIDKLKKGPKEANGAVPNPDRIVKMQVAADVK
Sequences:
>Translated_194_residues MMSRLIGRREFTGLAFATAFAAPAMAQTAKPAPKSDPQNTLYLDTAYGRVVIALRPDLAPAHVERLKTLTREGYYNNAPF HRVIDGFMAQTGDGQYGNGTGGSKYPNLKAEFSNTPFVRGTVGMARASSPDSANSQFFICYADSSFLNGQYTVVGQVVSG MEFIDKLKKGPKEANGAVPNPDRIVKMQVAADVK >Mature_194_residues MMSRLIGRREFTGLAFATAFAAPAMAQTAKPAPKSDPQNTLYLDTAYGRVVIALRPDLAPAHVERLKTLTREGYYNNAPF HRVIDGFMAQTGDGQYGNGTGGSKYPNLKAEFSNTPFVRGTVGMARASSPDSANSQFFICYADSSFLNGQYTVVGQVVSG MEFIDKLKKGPKEANGAVPNPDRIVKMQVAADVK
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI19557636, Length=148, Percent_Identity=37.1621621621622, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI7706339, Length=143, Percent_Identity=34.965034965035, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI5031987, Length=141, Percent_Identity=36.1702127659575, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI24308049, Length=158, Percent_Identity=36.0759493670886, Blast_Score=80, Evalue=9e-16, Organism=Homo sapiens, GI4758950, Length=178, Percent_Identity=32.5842696629214, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI10863927, Length=141, Percent_Identity=35.4609929078014, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4505991, Length=177, Percent_Identity=32.2033898305085, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI45439316, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI303305009, Length=182, Percent_Identity=30.2197802197802, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI169163387, Length=97, Percent_Identity=40.2061855670103, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI169164185, Length=97, Percent_Identity=40.2061855670103, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI169163623, Length=97, Percent_Identity=40.2061855670103, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI5174637, Length=164, Percent_Identity=30.4878048780488, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI310129267, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI310120620, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4826932, Length=150, Percent_Identity=32, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI310110104, Length=142, Percent_Identity=32.3943661971831, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI169214050, Length=169, Percent_Identity=31.3609467455621, Blast_Score=69, Evalue=2e-12, Organism=Escherichia coli, GI1786736, Length=154, Percent_Identity=40.2597402597403, Blast_Score=96, Evalue=1e-21, Organism=Escherichia coli, GI1789763, Length=172, Percent_Identity=39.5348837209302, Blast_Score=93, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17506311, Length=134, Percent_Identity=37.3134328358209, Blast_Score=84, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17539498, Length=128, Percent_Identity=36.71875, Blast_Score=81, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17539496, Length=145, Percent_Identity=35.1724137931034, Blast_Score=78, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17552780, Length=145, Percent_Identity=35.1724137931034, Blast_Score=77, Evalue=5e-15, Organism=Caenorhabditis elegans, GI71980594, Length=132, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71980590, Length=132, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17566266, Length=145, Percent_Identity=33.1034482758621, Blast_Score=76, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17565860, Length=135, Percent_Identity=34.8148148148148, Blast_Score=74, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17532643, Length=152, Percent_Identity=34.2105263157895, Blast_Score=73, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17559074, Length=147, Percent_Identity=31.9727891156463, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17552782, Length=148, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17506307, Length=145, Percent_Identity=35.1724137931034, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17532641, Length=141, Percent_Identity=32.6241134751773, Blast_Score=67, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6320359, Length=129, Percent_Identity=37.984496124031, Blast_Score=75, Evalue=8e-15, Organism=Saccharomyces cerevisiae, GI6323562, Length=132, Percent_Identity=32.5757575757576, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6321848, Length=139, Percent_Identity=33.8129496402878, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI17986117, Length=152, Percent_Identity=35.5263157894737, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI24664125, Length=141, Percent_Identity=37.5886524822695, Blast_Score=88, Evalue=3e-18, Organism=Drosophila melanogaster, GI21357783, Length=141, Percent_Identity=37.5886524822695, Blast_Score=88, Evalue=3e-18, Organism=Drosophila melanogaster, GI45549139, Length=129, Percent_Identity=36.4341085271318, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI17647301, Length=153, Percent_Identity=34.640522875817, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI19922376, Length=148, Percent_Identity=33.7837837837838, Blast_Score=75, Evalue=2e-14, Organism=Drosophila melanogaster, GI24652460, Length=151, Percent_Identity=33.7748344370861, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI20130249, Length=152, Percent_Identity=35.5263157894737, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24661775, Length=149, Percent_Identity=30.2013422818792, Blast_Score=67, Evalue=6e-12, Organism=Drosophila melanogaster, GI21355237, Length=149, Percent_Identity=30.2013422818792, Blast_Score=67, Evalue=6e-12, Organism=Drosophila melanogaster, GI24661771, Length=149, Percent_Identity=30.2013422818792, Blast_Score=67, Evalue=6e-12,
Paralogues:
None
Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 20936; Mature: 20936
Theoretical pI: Translated: 9.86; Mature: 9.86
Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMSRLIGRREFTGLAFATAFAAPAMAQTAKPAPKSDPQNTLYLDTAYGRVVIALRPDLAP CCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECCCCCH AHVERLKTLTREGYYNNAPFHRVIDGFMAQTGDGQYGNGTGGSKYPNLKAEFSNTPFVRG HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEE TVGMARASSPDSANSQFFICYADSSFLNGQYTVVGQVVSGMEFIDKLKKGPKEANGAVPN CCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC PDRIVKMQVAADVK CCCEEEEEEEECCC >Mature Secondary Structure MMSRLIGRREFTGLAFATAFAAPAMAQTAKPAPKSDPQNTLYLDTAYGRVVIALRPDLAP CCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECCCCCH AHVERLKTLTREGYYNNAPFHRVIDGFMAQTGDGQYGNGTGGSKYPNLKAEFSNTPFVRG HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEE TVGMARASSPDSANSQFFICYADSSFLNGQYTVVGQVVSGMEFIDKLKKGPKEANGAVPN CCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC PDRIVKMQVAADVK CCCEEEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA