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The map label for this gene is cysW [H]

Identifier: 158423719

GI number: 158423719

Start: 2408725

End: 2409606

Strand: Direct

Name: cysW [H]

Synonym: AZC_2095

Alternate gene names: 158423719

Gene position: 2408725-2409606 (Clockwise)

Preceding gene: 158423718

Following gene: 158423722

Centisome position: 44.86

GC content: 68.93

Gene sequence:

>882_bases
ATGGCGCCGCACGAAGGCACGAGATCCATGGCACAGAGCGCAAAGCAGGGCCGCTCCATTCCCATCGCCGGGCGGGGCGT
GCGGCTGGCATTCGCGCTGCCGGGTCTTCTGGTGCTGGCGCTGTTCTTCGTCCTGCCGCTCGGCAGCATTGCGCGCGAGG
CCTTCAGCGAGGGCGGATCGGCCTTCGCTCGTGTGCTGGCCGATCCGGTCTTCTGGGGTGGCGTGCGCGGCTCGCTCATC
CTCGGCACGCTGGCGCCGGGCTTCTCGGTGGTGGTGGGCTTCCTCGTGGCGCTGCATCTCGCCACCTTGTCCGAACGGGC
GCGCGGTCTGGCCCTGTTCGCCATTTCCCTGCCGCTGACCTTCTCCGGCCTCGTGATCGCCTATGGCTTCATTCTGGTGT
TCGGACGCTCGGGTTTCGTGACCCTGCTGCTGGCGCGGCTCGGCGCCGATCCGGCCGTTGTGGGCGGCTTCATCTTCACG
CCGGTGGGGCTGGGCCTTGCCTATTCCTATTATCTGATCCCCCGCGTGGTGCTGGTGATGCTGCCGGTGCTGACCAATTT
CGACCGCAGCCAGATCGCCGCCGCCCGCTCGCTGGGCGCCACCGGCTTCACCGCGCATCTGGACATTCTGGTGCCGCAGG
TGATGCCGGCGCTGATCACGGCCTTCTGCCTCACCTCCGCGGTTGCCATCGGAGCCTATGGCACGGCGCTGGCGCTCGTG
GGCACGCAGGTGAACATCCTGCCGCTGGTGCTCTACAGCAAGGTCTCCGACGCCGGCTCGGACTTCCCGGCGGCGGCCGC
CATCTCGCTGCTCCTCATGGGCCTGTGCTGCGCGGTTATCGGCCTCGCCGAACTGGTTCGCCGCGCGCGCCCCGCCGCCT
GA

Upstream 100 bases:

>100_bases
AGAAGGCCGAGATCGACCAGCTCTGGGCCAAGCAGGTGCTCGGCCAGTGAGGTGAGCCGAAGGGCCGGCGTCGCGCCGGC
CCTTCTCCCGTTTTCGACAG

Downstream 100 bases:

>100_bases
ACGCTTCCCACCCAAAAGGAAAGGCCGGGCGTCTCGCGACGCCCGGCCTTCTTCATGTACCCCCCGAGGGTCGGCTCAGA
ATTTGACCGTCAGCGCGCCG

Product: ABC transporter permease

Products: phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAPHEGTRSMAQSAKQGRSIPIAGRGVRLAFALPGLLVLALFFVLPLGSIAREAFSEGGSAFARVLADPVFWGGVRGSLI
LGTLAPGFSVVVGFLVALHLATLSERARGLALFAISLPLTFSGLVIAYGFILVFGRSGFVTLLLARLGADPAVVGGFIFT
PVGLGLAYSYYLIPRVVLVMLPVLTNFDRSQIAAARSLGATGFTAHLDILVPQVMPALITAFCLTSAVAIGAYGTALALV
GTQVNILPLVLYSKVSDAGSDFPAAAAISLLLMGLCCAVIGLAELVRRARPAA

Sequences:

>Translated_293_residues
MAPHEGTRSMAQSAKQGRSIPIAGRGVRLAFALPGLLVLALFFVLPLGSIAREAFSEGGSAFARVLADPVFWGGVRGSLI
LGTLAPGFSVVVGFLVALHLATLSERARGLALFAISLPLTFSGLVIAYGFILVFGRSGFVTLLLARLGADPAVVGGFIFT
PVGLGLAYSYYLIPRVVLVMLPVLTNFDRSQIAAARSLGATGFTAHLDILVPQVMPALITAFCLTSAVAIGAYGTALALV
GTQVNILPLVLYSKVSDAGSDFPAAAAISLLLMGLCCAVIGLAELVRRARPAA
>Mature_292_residues
APHEGTRSMAQSAKQGRSIPIAGRGVRLAFALPGLLVLALFFVLPLGSIAREAFSEGGSAFARVLADPVFWGGVRGSLIL
GTLAPGFSVVVGFLVALHLATLSERARGLALFAISLPLTFSGLVIAYGFILVFGRSGFVTLLLARLGADPAVVGGFIFTP
VGLGLAYSYYLIPRVVLVMLPVLTNFDRSQIAAARSLGATGFTAHLDILVPQVMPALITAFCLTSAVAIGAYGTALALVG
TQVNILPLVLYSKVSDAGSDFPAAAAISLLLMGLCCAVIGLAELVRRARPAA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787369, Length=259, Percent_Identity=26.2548262548263, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30224; Mature: 30093

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPHEGTRSMAQSAKQGRSIPIAGRGVRLAFALPGLLVLALFFVLPLGSIAREAFSEGGS
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHH
AFARVLADPVFWGGVRGSLILGTLAPGFSVVVGFLVALHLATLSERARGLALFAISLPLT
HHHHHHHCHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHH
FSGLVIAYGFILVFGRSGFVTLLLARLGADPAVVGGFIFTPVGLGLAYSYYLIPRVVLVM
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPVLTNFDRSQIAAARSLGATGFTAHLDILVPQVMPALITAFCLTSAVAIGAYGTALALV
HHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTQVNILPLVLYSKVSDAGSDFPAAAAISLLLMGLCCAVIGLAELVRRARPAA
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
APHEGTRSMAQSAKQGRSIPIAGRGVRLAFALPGLLVLALFFVLPLGSIAREAFSEGGS
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHH
AFARVLADPVFWGGVRGSLILGTLAPGFSVVVGFLVALHLATLSERARGLALFAISLPLT
HHHHHHHCHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHH
FSGLVIAYGFILVFGRSGFVTLLLARLGADPAVVGGFIFTPVGLGLAYSYYLIPRVVLVM
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPVLTNFDRSQIAAARSLGATGFTAHLDILVPQVMPALITAFCLTSAVAIGAYGTALALV
HHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTQVNILPLVLYSKVSDAGSDFPAAAAISLLLMGLCCAVIGLAELVRRARPAA
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]