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The map label for this gene is tctD [H]

Identifier: 158423577

GI number: 158423577

Start: 2254233

End: 2254895

Strand: Direct

Name: tctD [H]

Synonym: AZC_1953

Alternate gene names: 158423577

Gene position: 2254233-2254895 (Clockwise)

Preceding gene: 158423572

Following gene: 158423578

Centisome position: 41.98

GC content: 67.72

Gene sequence:

>663_bases
ATGCGCATCCTGCTGGTCGAGGACACCGAAGAGATCGGCCGCGCCATCGCGAAGCGGTTCGAGCGCATTGGTTACGCGGT
GGACTGGGAGCGCGACGGGCGCACCGCGGCCGAGCTTCTGGAAGTGCAAAGCTATGATCTCGTTGTGCTGGACGTGATGC
TGCCTCGGCAGGATGGGTTCAGCGTTCTCAAGGGGTTGCGCGGGCGTGGGGTGCGCACGCCGGTGCTGGTGCTCACCGCC
CGGTCCGCCGTCGACGACCGCATCAGCGCCCTCGATCTCGGCGCCGATGACTATCTGATCAAGCCGTTCGATTATCGCGA
GCTGGAAGCCCGCGCCCGCGCGCTGCTGCGCCGGGCGGCGGGCCAGTCGGACAATCTGCTGCGGCTTGGCCCGTTGACCA
TCGACCGGGCCGGCCGCACCGCAAGCGTCGAGGGCAAGGCGCTCGACCTGACCCGGCGCGAGCTGACCGTTCTGGAAATC
CTCGCCTCCCGCCCCGGCCGGTTCGTGCCGAAGGAAGAATTGGTGGAGCAGCTCTTCAGCTTCGATCAGGACCCGAGCCC
CAATGCCGTGGAGCAGTTCGTGGCGCGCCTGCGCCGCAAGCTTGCCGCGACGCCAGTCGAGATCCGGACAGAGCGCGGCC
TTGGCTATCAGCTCGCGACTTGA

Upstream 100 bases:

>100_bases
TCTGCGCCGTGGCGAATTTTGTTTGGTGCACTCTGGCAGCCTTGGTAAGAACGATACGGGCATTCACTGACACGAAACTG
ACTCCAGCCGACGAAGAGCC

Downstream 100 bases:

>100_bases
AAGCCTGCGCACCTCGCTGCGCGCGCGCATCCTCGCCCTCGTCGGCATCATGCTGGCGCTGGGCGCGCTGCTGCTGAGCT
TCGCGGCGTGGGAATATGCC

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRILLVEDTEEIGRAIAKRFERIGYAVDWERDGRTAAELLEVQSYDLVVLDVMLPRQDGFSVLKGLRGRGVRTPVLVLTA
RSAVDDRISALDLGADDYLIKPFDYRELEARARALLRRAAGQSDNLLRLGPLTIDRAGRTASVEGKALDLTRRELTVLEI
LASRPGRFVPKEELVEQLFSFDQDPSPNAVEQFVARLRRKLAATPVEIRTERGLGYQLAT

Sequences:

>Translated_220_residues
MRILLVEDTEEIGRAIAKRFERIGYAVDWERDGRTAAELLEVQSYDLVVLDVMLPRQDGFSVLKGLRGRGVRTPVLVLTA
RSAVDDRISALDLGADDYLIKPFDYRELEARARALLRRAAGQSDNLLRLGPLTIDRAGRTASVEGKALDLTRRELTVLEI
LASRPGRFVPKEELVEQLFSFDQDPSPNAVEQFVARLRRKLAATPVEIRTERGLGYQLAT
>Mature_220_residues
MRILLVEDTEEIGRAIAKRFERIGYAVDWERDGRTAAELLEVQSYDLVVLDVMLPRQDGFSVLKGLRGRGVRTPVLVLTA
RSAVDDRISALDLGADDYLIKPFDYRELEARARALLRRAAGQSDNLLRLGPLTIDRAGRTASVEGKALDLTRRELTVLEI
LASRPGRFVPKEELVEQLFSFDQDPSPNAVEQFVARLRRKLAATPVEIRTERGLGYQLAT

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=43.8356164383562, Blast_Score=174, Evalue=3e-45,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=40.8256880733945, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=37.7272727272727, Blast_Score=146, Evalue=8e-37,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=36.1990950226244, Blast_Score=144, Evalue=3e-36,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=34.8623853211009, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=36.7965367965368, Blast_Score=114, Evalue=3e-27,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.841628959276, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=33.0316742081448, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=32, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=35.0649350649351, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.858407079646, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=29.4642857142857, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=29.3103448275862, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=38.8888888888889, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.962962962963, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=37.6237623762376, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=145, Percent_Identity=29.6551724137931, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=28.9256198347107, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24702; Mature: 24702

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDTEEIGRAIAKRFERIGYAVDWERDGRTAAELLEVQSYDLVVLDVMLPRQDGF
CEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCH
SVLKGLRGRGVRTPVLVLTARSAVDDRISALDLGADDYLIKPFDYRELEARARALLRRAA
HHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHC
GQSDNLLRLGPLTIDRAGRTASVEGKALDLTRRELTVLEILASRPGRFVPKEELVEQLFS
CCCCCEEEECCEEEECCCCEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
FDQDPSPNAVEQFVARLRRKLAATPVEIRTERGLGYQLAT
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECC
>Mature Secondary Structure
MRILLVEDTEEIGRAIAKRFERIGYAVDWERDGRTAAELLEVQSYDLVVLDVMLPRQDGF
CEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCH
SVLKGLRGRGVRTPVLVLTARSAVDDRISALDLGADDYLIKPFDYRELEARARALLRRAA
HHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHC
GQSDNLLRLGPLTIDRAGRTASVEGKALDLTRRELTVLEILASRPGRFVPKEELVEQLFS
CCCCCEEEECCEEEECCCCEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
FDQDPSPNAVEQFVARLRRKLAATPVEIRTERGLGYQLAT
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]