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The map label for this gene is yjmC [H]

Identifier: 158423506

GI number: 158423506

Start: 2155969

End: 2157021

Strand: Direct

Name: yjmC [H]

Synonym: AZC_1882

Alternate gene names: 158423506

Gene position: 2155969-2157021 (Clockwise)

Preceding gene: 158423505

Following gene: 158423507

Centisome position: 40.15

GC content: 71.32

Gene sequence:

>1053_bases
ATGAGCGGCACGCCGCTCACCCTCGCGCCGGAGGCGCTCTCGGCCTTTGCGGCGGGCCTGCTGGAGGCGGGCGGGTTCCG
CCCCGCCGATGCGAAGAAATCCGCAGATCTGCTCGTCTGGGCCAATCAGCGCGGCGTGGACTCCCACGGCGTGCTGCGCA
TTCCGCGCTATGTGGAGATGGTGGGGCTTGGCCTAATCAATCCGGCCGCCGAGCCGAAGGTGGTGAACGAATGGGGGGCC
GTGGCTCTGATTGATGCGGGTCTTGCACCCGGCGCATCGGCCATGGAGCAGGTGACGGACAAGGCCATTGAGATCGCCGG
CCGCCTTGGCGGCGGTTTCTGTGTCGGCCGGAATGTCACCCATGCCGGCGCGGTGGGCTATTTTGCCCACCGCATCGCCG
CCCGAGGGCTGGTGGGCATTGTGATGACGGCCTCCAAGCCGCTCATGGCCTATCCCGGCGCGCGGGGGGAGGTGGTATCC
TCCAATCCGCTTGCCATCGCCGCGCCCTCGGAAGTTGCGGGCGAGCCCATCGTCCTCGACATGTCCACCGCAGCGGTTGC
CCTCGGCCAGGTTTTGGCCGCCCGCGACGCCGGCCGGACCATTCCGGAAGGCTGGGGCATCGATGCCGCCGGCCGCCCCA
CGACGGACCCCGCCGCCGTGCAGGCGCTCACCCCCATGGCCGGCGCCAAGGGGGCGGGACTGTCGCTGATGATCGAAGTG
CTCTGCTCCCTGCTGGCGGGCAATCCCCTCATCGCCCCGGCGCTGTCCGGCGCGGCGCCGGCCGGCTTCAACGGCTTCGT
CGCCGCTATTGATCCGGGGGCCTTCGGCTCGCGGGAGCGCTTTCTGGGGGACGTCCGTGGGCTTGCGGCCGCGATCCACG
GGCTGCCGCCGGCAGAGGGGACGCAGGCCGTGCTCCTGCCGGGCGAGCGCGGGCGTCGCACGGCCGAGACCCGCCGCTCC
GGCATCCCGCTGGCGCGGGGCACCTCCTCGAAGCTCAAGGAACTGGCAACCCGGCTCGGGGTGACGATCCCCGAAGCTCT
CCAAGCGGCCTGA

Upstream 100 bases:

>100_bases
CGTCGCACTTCCCGCTGTCGGAGCAGGATGCGCCGCGCACCAAGCTGATGATCAGGGGCTGGCTGGACAAGTTCTTCCCT
TCGCCGCTCGGGGGGGCGGC

Downstream 100 bases:

>100_bases
ACCGGCACAAGACCGGACATCGGCGGCATCAGACCGCCACGGGAAGGAAACGTGCCATGAAGCTCCTGTCCTATGCGATA
GGGGGTGCTGAAAGCTGGGG

Product: malate/L-lactate dehydrogenase

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSGTPLTLAPEALSAFAAGLLEAGGFRPADAKKSADLLVWANQRGVDSHGVLRIPRYVEMVGLGLINPAAEPKVVNEWGA
VALIDAGLAPGASAMEQVTDKAIEIAGRLGGGFCVGRNVTHAGAVGYFAHRIAARGLVGIVMTASKPLMAYPGARGEVVS
SNPLAIAAPSEVAGEPIVLDMSTAAVALGQVLAARDAGRTIPEGWGIDAAGRPTTDPAAVQALTPMAGAKGAGLSLMIEV
LCSLLAGNPLIAPALSGAAPAGFNGFVAAIDPGAFGSRERFLGDVRGLAAAIHGLPPAEGTQAVLLPGERGRRTAETRRS
GIPLARGTSSKLKELATRLGVTIPEALQAA

Sequences:

>Translated_350_residues
MSGTPLTLAPEALSAFAAGLLEAGGFRPADAKKSADLLVWANQRGVDSHGVLRIPRYVEMVGLGLINPAAEPKVVNEWGA
VALIDAGLAPGASAMEQVTDKAIEIAGRLGGGFCVGRNVTHAGAVGYFAHRIAARGLVGIVMTASKPLMAYPGARGEVVS
SNPLAIAAPSEVAGEPIVLDMSTAAVALGQVLAARDAGRTIPEGWGIDAAGRPTTDPAAVQALTPMAGAKGAGLSLMIEV
LCSLLAGNPLIAPALSGAAPAGFNGFVAAIDPGAFGSRERFLGDVRGLAAAIHGLPPAEGTQAVLLPGERGRRTAETRRS
GIPLARGTSSKLKELATRLGVTIPEALQAA
>Mature_349_residues
SGTPLTLAPEALSAFAAGLLEAGGFRPADAKKSADLLVWANQRGVDSHGVLRIPRYVEMVGLGLINPAAEPKVVNEWGAV
ALIDAGLAPGASAMEQVTDKAIEIAGRLGGGFCVGRNVTHAGAVGYFAHRIAARGLVGIVMTASKPLMAYPGARGEVVSS
NPLAIAAPSEVAGEPIVLDMSTAAVALGQVLAARDAGRTIPEGWGIDAAGRPTTDPAAVQALTPMAGAKGAGLSLMIEVL
CSLLAGNPLIAPALSGAAPAGFNGFVAAIDPGAFGSRERFLGDVRGLAAAIHGLPPAEGTQAVLLPGERGRRTAETRRSG
IPLARGTSSKLKELATRLGVTIPEALQAA

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=308, Percent_Identity=33.4415584415584, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790000, Length=336, Percent_Identity=28.5714285714286, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787020, Length=355, Percent_Identity=30.4225352112676, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17507179, Length=358, Percent_Identity=29.3296089385475, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17536633, Length=357, Percent_Identity=28.5714285714286, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24667908, Length=300, Percent_Identity=32, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24667904, Length=313, Percent_Identity=31.3099041533546, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI45553211, Length=300, Percent_Identity=32, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24667912, Length=300, Percent_Identity=32, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24658010, Length=346, Percent_Identity=30.0578034682081, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24648360, Length=332, Percent_Identity=25.9036144578313, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 35197; Mature: 35066

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTPLTLAPEALSAFAAGLLEAGGFRPADAKKSADLLVWANQRGVDSHGVLRIPRYVEM
CCCCCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEECHHHHHH
VGLGLINPAAEPKVVNEWGAVALIDAGLAPGASAMEQVTDKAIEIAGRLGGGFCVGRNVT
HHCCCCCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCC
HAGAVGYFAHRIAARGLVGIVMTASKPLMAYPGARGEVVSSNPLAIAAPSEVAGEPIVLD
HHHHHHHHHHHHHHHHHEEEEEECCCCCEECCCCCCCEECCCCEEEECCHHHCCCCEEEE
MSTAAVALGQVLAARDAGRTIPEGWGIDAAGRPTTDPAAVQALTPMAGAKGAGLSLMIEV
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHH
LCSLLAGNPLIAPALSGAAPAGFNGFVAAIDPGAFGSRERFLGDVRGLAAAIHGLPPAEG
HHHHHCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
TQAVLLPGERGRRTAETRRSGIPLARGTSSKLKELATRLGVTIPEALQAA
CEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
SGTPLTLAPEALSAFAAGLLEAGGFRPADAKKSADLLVWANQRGVDSHGVLRIPRYVEM
CCCCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEECHHHHHH
VGLGLINPAAEPKVVNEWGAVALIDAGLAPGASAMEQVTDKAIEIAGRLGGGFCVGRNVT
HHCCCCCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCC
HAGAVGYFAHRIAARGLVGIVMTASKPLMAYPGARGEVVSSNPLAIAAPSEVAGEPIVLD
HHHHHHHHHHHHHHHHHEEEEEECCCCCEECCCCCCCEECCCCEEEECCHHHCCCCEEEE
MSTAAVALGQVLAARDAGRTIPEGWGIDAAGRPTTDPAAVQALTPMAGAKGAGLSLMIEV
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHH
LCSLLAGNPLIAPALSGAAPAGFNGFVAAIDPGAFGSRERFLGDVRGLAAAIHGLPPAEG
HHHHHCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
TQAVLLPGERGRRTAETRRSGIPLARGTSSKLKELATRLGVTIPEALQAA
CEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]