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The map label for this gene is mcp4 [H]

Identifier: 158423345

GI number: 158423345

Start: 1970360

End: 1972039

Strand: Direct

Name: mcp4 [H]

Synonym: AZC_1721

Alternate gene names: 158423345

Gene position: 1970360-1972039 (Clockwise)

Preceding gene: 158423343

Following gene: 158423346

Centisome position: 36.69

GC content: 65.48

Gene sequence:

>1680_bases
ATGTTGAAGAACATGTCCATCAGGGCGAAGATCCTGCTCGCCTTCGCCGTCGTTCTGCTCGCCAATATCTGCAGCGGGGC
GGTCATCCTGATGTCCAGTCGGACCGTTGACCGCAATGTGAACTGGACCATCCATACCTATGAGGTCCTGACGGAAGCTG
ATCAGCTTCTGATCTCGCTCATCAATCAGGAGACGGGCCTGCGCGGCTATCTCGTCACCGGCAAGACCTCCAGCCTTGAG
CCCCTCACGGCGGGTGAAGCCGGCTATCGGCAGGCGTGGGCCAAGCTGAAGTCGCTCACCAGCGACAATGCCGTCCAGCA
GCAGCGTCTCGATGCCATGCAGAAAGAGGTCGAGCAGTGGCAGCAGAACGTCTCGCGCGCCGCCATCGATCTCATGGGCA
AGCCTGGACAGGAAAGCGCCGCGCAAGACATCGAGCGTTCCGGCAAGGGCAAGGCGAACTTCGACAAGATCCGGTCGATC
CTGACCGACTTCAAGGGTGCCGAGGCGTCGCTGCTTGAGGCGCGCGCCCAGGCCGTGGCGGCCGCGCAAACCGCCATCGT
CTATGCGGTCGTGCTGGCAGTGCTCGCCGTTCTGGCGCTGGCCGTCCTTGCAGCCGTCGCCCTGAATGCCCTGCTTGCCA
AGCCCATCCGCCGCGCCATCACCTCCATGGAGAAGATAAAGGGCGGCGACTACGCGACGCAGATCGACGACACCGACCGC
CGGGACGAAATCGGCCTCATGGGCAATGCGCTGGTGTCGTTCCGCGACAGCCTCGGCGAGGCTGATCGCCTGGCCAAGGA
AAACGCCGCGCGCGATGAAGTGGAGCGTCAGAGGCTCGCCAAGCGCAACACCCTCGCGGCCGACTTCGTCTCCCGCATGA
CCGAGCTCTCGGCCGCCTTCGCTGCTTCTTCCGGGCAGGTGGCAAGCTCCGCCCGCAACCTGTCGGCCACGGCCGAGCAG
ACCTCCCGGCAAGCGCAGGCGGTGGCCTCGGCTGCCGAGGAAGCGGCGGAGAATGTGCAGACGGTTGCGGCCTCGTCCGA
GGAACTGGCCGCTTCCGTTCGCGAGATCACCGGCCAGGTGAGCCATTCCGCCCAGGTCGCGGACGTCGCCTTCACTGAGG
CTGAGAAGTCCAACAGCCGCATCGGCGAACTCGCCACGGCGGCCACCGCCATCGGCGACGTGATCTCCCTCATCAAGGGC
ATCGCCGACCAGACCAACCTGCTGGCGCTCAACGCCACCATCGAATCCGCCCGTGCCGGCGAAGCGGGCAAGGGTTTTGC
CGTGGTGGCCTCCGAGGTGAAGCAACTCGCCTCTCAGACGGCCCGGGCGACCGACGAGATCGCCGCCAAGGTTGCGGAGA
TCCAGCAATCCACGCAGGGCACCGTCACCTCCATGGCGGAGATCATGCGGGTGATCGCCAACATGAAGCAGATCTCCTCC
TCCATCGCCGGCGCGGTGGAAGAGCAGGGCGCTGCCACCGGCGAGATCGCCGAGAACTGCCAGCGTGCCTCCAGCGGCAC
GCAGATGGTGACGCAGAACATCAGCGGCGTCGGGCAGGCTGCCCAGCTCACCGGCTCCGCCTCCACTGAACTTCTGGCGT
TGTCCGAAGGGCTCTCCGGTCAGGCGGGCGATCTGAAGCAACTGGTGGAGACCTTCGTTCGGGACCTCAACGCCGCCTGA

Upstream 100 bases:

>100_bases
GCTTTGGAGGTTGATTCCGTATCCATCGCCACACGCACCGTGCCAATTTCGCCCCAGGCATCGAAACGGCTGTTGCTAGC
CAAGAATTCCGGGGCGCCGT

Downstream 100 bases:

>100_bases
GCCGCAATCCGCCGCTCATCGCCGGACCCCAGCATCCCCCGCGACGCACGCGGGGGATGCTCTGCTTTCAAGGGGCCTGC
TGCGCACGTCTCCGCGCCGA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MLKNMSIRAKILLAFAVVLLANICSGAVILMSSRTVDRNVNWTIHTYEVLTEADQLLISLINQETGLRGYLVTGKTSSLE
PLTAGEAGYRQAWAKLKSLTSDNAVQQQRLDAMQKEVEQWQQNVSRAAIDLMGKPGQESAAQDIERSGKGKANFDKIRSI
LTDFKGAEASLLEARAQAVAAAQTAIVYAVVLAVLAVLALAVLAAVALNALLAKPIRRAITSMEKIKGGDYATQIDDTDR
RDEIGLMGNALVSFRDSLGEADRLAKENAARDEVERQRLAKRNTLAADFVSRMTELSAAFAASSGQVASSARNLSATAEQ
TSRQAQAVASAAEEAAENVQTVAASSEELAASVREITGQVSHSAQVADVAFTEAEKSNSRIGELATAATAIGDVISLIKG
IADQTNLLALNATIESARAGEAGKGFAVVASEVKQLASQTARATDEIAAKVAEIQQSTQGTVTSMAEIMRVIANMKQISS
SIAGAVEEQGAATGEIAENCQRASSGTQMVTQNISGVGQAAQLTGSASTELLALSEGLSGQAGDLKQLVETFVRDLNAA

Sequences:

>Translated_559_residues
MLKNMSIRAKILLAFAVVLLANICSGAVILMSSRTVDRNVNWTIHTYEVLTEADQLLISLINQETGLRGYLVTGKTSSLE
PLTAGEAGYRQAWAKLKSLTSDNAVQQQRLDAMQKEVEQWQQNVSRAAIDLMGKPGQESAAQDIERSGKGKANFDKIRSI
LTDFKGAEASLLEARAQAVAAAQTAIVYAVVLAVLAVLALAVLAAVALNALLAKPIRRAITSMEKIKGGDYATQIDDTDR
RDEIGLMGNALVSFRDSLGEADRLAKENAARDEVERQRLAKRNTLAADFVSRMTELSAAFAASSGQVASSARNLSATAEQ
TSRQAQAVASAAEEAAENVQTVAASSEELAASVREITGQVSHSAQVADVAFTEAEKSNSRIGELATAATAIGDVISLIKG
IADQTNLLALNATIESARAGEAGKGFAVVASEVKQLASQTARATDEIAAKVAEIQQSTQGTVTSMAEIMRVIANMKQISS
SIAGAVEEQGAATGEIAENCQRASSGTQMVTQNISGVGQAAQLTGSASTELLALSEGLSGQAGDLKQLVETFVRDLNAA
>Mature_559_residues
MLKNMSIRAKILLAFAVVLLANICSGAVILMSSRTVDRNVNWTIHTYEVLTEADQLLISLINQETGLRGYLVTGKTSSLE
PLTAGEAGYRQAWAKLKSLTSDNAVQQQRLDAMQKEVEQWQQNVSRAAIDLMGKPGQESAAQDIERSGKGKANFDKIRSI
LTDFKGAEASLLEARAQAVAAAQTAIVYAVVLAVLAVLALAVLAAVALNALLAKPIRRAITSMEKIKGGDYATQIDDTDR
RDEIGLMGNALVSFRDSLGEADRLAKENAARDEVERQRLAKRNTLAADFVSRMTELSAAFAASSGQVASSARNLSATAEQ
TSRQAQAVASAAEEAAENVQTVAASSEELAASVREITGQVSHSAQVADVAFTEAEKSNSRIGELATAATAIGDVISLIKG
IADQTNLLALNATIESARAGEAGKGFAVVASEVKQLASQTARATDEIAAKVAEIQQSTQGTVTSMAEIMRVIANMKQISS
SIAGAVEEQGAATGEIAENCQRASSGTQMVTQNISGVGQAAQLTGSASTELLALSEGLSGQAGDLKQLVETFVRDLNAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=376, Percent_Identity=31.1170212765957, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788194, Length=239, Percent_Identity=35.5648535564854, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=30.5647840531561, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI2367378, Length=373, Percent_Identity=28.1501340482574, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=204, Percent_Identity=36.2745098039216, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58627; Mature: 58627

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNMSIRAKILLAFAVVLLANICSGAVILMSSRTVDRNVNWTIHTYEVLTEADQLLISL
CCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHH
INQETGLRGYLVTGKTSSLEPLTAGEAGYRQAWAKLKSLTSDNAVQQQRLDAMQKEVEQW
HHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QQNVSRAAIDLMGKPGQESAAQDIERSGKGKANFDKIRSILTDFKGAEASLLEARAQAVA
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAQTAIVYAVVLAVLAVLALAVLAAVALNALLAKPIRRAITSMEKIKGGDYATQIDDTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RDEIGLMGNALVSFRDSLGEADRLAKENAARDEVERQRLAKRNTLAADFVSRMTELSAAF
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASSGQVASSARNLSATAEQTSRQAQAVASAAEEAAENVQTVAASSEELAASVREITGQV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SHSAQVADVAFTEAEKSNSRIGELATAATAIGDVISLIKGIADQTNLLALNATIESARAG
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCCC
EAGKGFAVVASEVKQLASQTARATDEIAAKVAEIQQSTQGTVTSMAEIMRVIANMKQISS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SIAGAVEEQGAATGEIAENCQRASSGTQMVTQNISGVGQAAQLTGSASTELLALSEGLSG
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHCCCCC
QAGDLKQLVETFVRDLNAA
CCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKNMSIRAKILLAFAVVLLANICSGAVILMSSRTVDRNVNWTIHTYEVLTEADQLLISL
CCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHH
INQETGLRGYLVTGKTSSLEPLTAGEAGYRQAWAKLKSLTSDNAVQQQRLDAMQKEVEQW
HHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
QQNVSRAAIDLMGKPGQESAAQDIERSGKGKANFDKIRSILTDFKGAEASLLEARAQAVA
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAQTAIVYAVVLAVLAVLALAVLAAVALNALLAKPIRRAITSMEKIKGGDYATQIDDTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RDEIGLMGNALVSFRDSLGEADRLAKENAARDEVERQRLAKRNTLAADFVSRMTELSAAF
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASSGQVASSARNLSATAEQTSRQAQAVASAAEEAAENVQTVAASSEELAASVREITGQV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SHSAQVADVAFTEAEKSNSRIGELATAATAIGDVISLIKGIADQTNLLALNATIESARAG
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHCCC
EAGKGFAVVASEVKQLASQTARATDEIAAKVAEIQQSTQGTVTSMAEIMRVIANMKQISS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SIAGAVEEQGAATGEIAENCQRASSGTQMVTQNISGVGQAAQLTGSASTELLALSEGLSG
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHCCCCC
QAGDLKQLVETFVRDLNAA
CCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]