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The map label for this gene is dppA [H]

Identifier: 158423178

GI number: 158423178

Start: 1767219

End: 1768895

Strand: Reverse

Name: dppA [H]

Synonym: AZC_1554

Alternate gene names: 158423178

Gene position: 1768895-1767219 (Counterclockwise)

Preceding gene: 158423180

Following gene: 158423177

Centisome position: 32.94

GC content: 67.2

Gene sequence:

>1677_bases
TTGCCCATGCTGTCTATCCGAAAGAGGCCTGCCCACCGTCTGCCGCTCACGCTCGCGGCCGCCCTTCTGACCGGCTGCAC
GCTCGTCTCGGGCGCGGCGCTGGCCGAGAGCACGCTGCGCATCGGCATGACGGCGGCGGACATCCCGCGCACCCTCGGAC
AGCCGGACCAGGGCTTCGAGGGCAACCGCTTCACCGGCCTCACCATGTATGACGCGCTGGTGAACTGGGACCTGTCCTCC
GCCACCAAGCCTTCGGTTCTGGTGCCGGGCCTCGCCACCGAATGGAAGGTGGACGACGCCGACAAGACCAAGTGGACCTT
CAAGCTGCGTCCCGACGTGAAGTTCCACGACGGCTCGCCCTTCAATGCCGATGCCGTGGTGTGGAACGTGGACAAGGTGC
TCAACCAGAGCGCCCCCCAGTTCGACGCCAGCCAGGTGGGCGTGACCGCCTCGCGCATGCCGACCCTCGTCTCGGCGAAG
AAGATCGACGACCTGACCGTTGAGCTGGTGACCAAGGAGCCGGACAGCTTCCTGCCCTACAACATCACCAATCTCTTCAT
GGCGAGCCCCACCCAGTGGAAGAAGTTCTTTGACGCGGCCGAGGGCGCCGACGCCAAGGCGAAATCGCAGGCCGCCTGGG
CCGCCTTCGCCAAGGATGCCTCCGGCACCGGCCCGTGGAAGATGTCCAAGTTCGTGCCGCGCGAGCGCCTCGAGCTGGTG
AAGAACACCGACTATTGGGACAAGGGCCGCGTGCCCAAGACCGACAAGATGGTGCTCCTGCCGATGCCGGAGGCCAATGC
CCGCACGGCGGCCCTCCTCGCCGGACAGGTGGACTGGATCGAGGCTCCAGCGCCGGACGCTCTGCCGCAGTTGCGCCAGC
GCGGCTTCATGATCCGCTCCAACGAGCAGCCGCACGTGTGGCCATGGCAATTCTCCCGCGTGGAAGGCTCGCCGTGGAAC
GACATCCGCGTGCGCAAGGCGGCCAATCTGTGCGTGGACCGCGAGGGCATGCGCGACGGCCTGCTCGGCGGCCTGATGGC
GCCGGCCACCGGCACGGTCGAGCCCGGCCACCCGTGGCGCGGCAATCCGACCTTCCAGATCAAGTATGATCCGGAAGCCG
GCAAGAAGCTGATGCAGGAGGCCGGCTTCGGCCCCAGCAAGAAGCTCACCGTCAAGATCCAGACGTCGGCCTCCGGCTCC
GGCCAGATGCTGCCGCTGCCCATGAACGAATATCTCCAGCAGGCGCTGGCCGAGTGCTATTTCGACGTGCAGCTCGACGT
CATCGAGTGGAACACGCTGTTCACCAACTGGCGCCGTGGCGCGAAGGACCCGAGCGCCAACGGCTCGAACGCCATCAACG
TCACCTATGCGGCGATGGACCCCTTCTTCGCCCTCGTGCGCTTCCTCCAGTCCGGCATGGCGCCGCCCACCTCGAACAAC
TGGGGCTTCATCAACAACCCCAAGTTCGACGAACTGGTGAAGAAGGCCCGCTCCACCTTCGACCCGGCGGCGCGCGACGC
GGCGCTGGCCGAACTGCACGCGGCCTCCGTGGACGACGCGGCCTTCCTCTACGTGGCCCACGACGTCGGCCCGCGGGCGC
TGAGCCCGAAGGTCTCCGGCCTCGTGCAGCCCAAGAGCTGGTTCGTGGACTTCTCGCCCGTGGTGGTGGCGCCGTGA

Upstream 100 bases:

>100_bases
GACAGATCGTCTGCTTTTTCTCCGTTTGCGCCCAACCTTACGCAACGTCCGCAACCTTGGCACAGCCGTTGCTTAGAACC
TGTCGAACCACAGGGGAAGC

Downstream 100 bases:

>100_bases
GAGGGGCGTGAAGGGCTGCAACTCGCAAATCGAGCCAAGCCTCTGCTCAACATGCGGGAGAGCCCTCCCCCCTTGCGGGG
GAGGGTTGGGAGGGGGGTAG

Product: ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MPMLSIRKRPAHRLPLTLAAALLTGCTLVSGAALAESTLRIGMTAADIPRTLGQPDQGFEGNRFTGLTMYDALVNWDLSS
ATKPSVLVPGLATEWKVDDADKTKWTFKLRPDVKFHDGSPFNADAVVWNVDKVLNQSAPQFDASQVGVTASRMPTLVSAK
KIDDLTVELVTKEPDSFLPYNITNLFMASPTQWKKFFDAAEGADAKAKSQAAWAAFAKDASGTGPWKMSKFVPRERLELV
KNTDYWDKGRVPKTDKMVLLPMPEANARTAALLAGQVDWIEAPAPDALPQLRQRGFMIRSNEQPHVWPWQFSRVEGSPWN
DIRVRKAANLCVDREGMRDGLLGGLMAPATGTVEPGHPWRGNPTFQIKYDPEAGKKLMQEAGFGPSKKLTVKIQTSASGS
GQMLPLPMNEYLQQALAECYFDVQLDVIEWNTLFTNWRRGAKDPSANGSNAINVTYAAMDPFFALVRFLQSGMAPPTSNN
WGFINNPKFDELVKKARSTFDPAARDAALAELHAASVDDAAFLYVAHDVGPRALSPKVSGLVQPKSWFVDFSPVVVAP

Sequences:

>Translated_558_residues
MPMLSIRKRPAHRLPLTLAAALLTGCTLVSGAALAESTLRIGMTAADIPRTLGQPDQGFEGNRFTGLTMYDALVNWDLSS
ATKPSVLVPGLATEWKVDDADKTKWTFKLRPDVKFHDGSPFNADAVVWNVDKVLNQSAPQFDASQVGVTASRMPTLVSAK
KIDDLTVELVTKEPDSFLPYNITNLFMASPTQWKKFFDAAEGADAKAKSQAAWAAFAKDASGTGPWKMSKFVPRERLELV
KNTDYWDKGRVPKTDKMVLLPMPEANARTAALLAGQVDWIEAPAPDALPQLRQRGFMIRSNEQPHVWPWQFSRVEGSPWN
DIRVRKAANLCVDREGMRDGLLGGLMAPATGTVEPGHPWRGNPTFQIKYDPEAGKKLMQEAGFGPSKKLTVKIQTSASGS
GQMLPLPMNEYLQQALAECYFDVQLDVIEWNTLFTNWRRGAKDPSANGSNAINVTYAAMDPFFALVRFLQSGMAPPTSNN
WGFINNPKFDELVKKARSTFDPAARDAALAELHAASVDDAAFLYVAHDVGPRALSPKVSGLVQPKSWFVDFSPVVVAP
>Mature_557_residues
PMLSIRKRPAHRLPLTLAAALLTGCTLVSGAALAESTLRIGMTAADIPRTLGQPDQGFEGNRFTGLTMYDALVNWDLSSA
TKPSVLVPGLATEWKVDDADKTKWTFKLRPDVKFHDGSPFNADAVVWNVDKVLNQSAPQFDASQVGVTASRMPTLVSAKK
IDDLTVELVTKEPDSFLPYNITNLFMASPTQWKKFFDAAEGADAKAKSQAAWAAFAKDASGTGPWKMSKFVPRERLELVK
NTDYWDKGRVPKTDKMVLLPMPEANARTAALLAGQVDWIEAPAPDALPQLRQRGFMIRSNEQPHVWPWQFSRVEGSPWND
IRVRKAANLCVDREGMRDGLLGGLMAPATGTVEPGHPWRGNPTFQIKYDPEAGKKLMQEAGFGPSKKLTVKIQTSASGSG
QMLPLPMNEYLQQALAECYFDVQLDVIEWNTLFTNWRRGAKDPSANGSNAINVTYAAMDPFFALVRFLQSGMAPPTSNNW
GFINNPKFDELVKKARSTFDPAARDAALAELHAASVDDAAFLYVAHDVGPRALSPKVSGLVQPKSWFVDFSPVVVAP

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=549, Percent_Identity=26.5938069216758, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87081878, Length=563, Percent_Identity=23.6234458259325, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787052, Length=479, Percent_Identity=24.6346555323591, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1787495, Length=565, Percent_Identity=23.716814159292, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789887, Length=541, Percent_Identity=24.0295748613678, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787762, Length=559, Percent_Identity=24.3291592128801, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787551, Length=506, Percent_Identity=23.5177865612648, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789397, Length=475, Percent_Identity=22.1052631578947, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61235; Mature: 61104

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMLSIRKRPAHRLPLTLAAALLTGCTLVSGAALAESTLRIGMTAADIPRTLGQPDQGFE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHCCCCCCCC
GNRFTGLTMYDALVNWDLSSATKPSVLVPGLATEWKVDDADKTKWTFKLRPDVKFHDGSP
CCCEECEEHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCEEECCCCC
FNADAVVWNVDKVLNQSAPQFDASQVGVTASRMPTLVSAKKIDDLTVELVTKEPDSFLPY
CCCCEEEEEHHHHHCCCCCCCCCHHCCCCHHHCCHHHHHHCCCCEEEEEEECCCCCCCCC
NITNLFMASPTQWKKFFDAAEGADAKAKSQAAWAAFAKDASGTGPWKMSKFVPRERLELV
CHHHEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHH
KNTDYWDKGRVPKTDKMVLLPMPEANARTAALLAGQVDWIEAPAPDALPQLRQRGFMIRS
HCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEECCCCCHHHHHHHHCCEEEEC
NEQPHVWPWQFSRVEGSPWNDIRVRKAANLCVDREGMRDGLLGGLMAPATGTVEPGHPWR
CCCCCCCCCEEECCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
GNPTFQIKYDPEAGKKLMQEAGFGPSKKLTVKIQTSASGSGQMLPLPMNEYLQQALAECY
CCCEEEEEECCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEECCHHHHHHHHHHHHE
FDVQLDVIEWNTLFTNWRRGAKDPSANGSNAINVTYAAMDPFFALVRFLQSGMAPPTSNN
EEEEEEEEECHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCC
WGFINNPKFDELVKKARSTFDPAARDAALAELHAASVDDAAFLYVAHDVGPRALSPKVSG
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHC
LVQPKSWFVDFSPVVVAP
EECCHHEEEECCCEEECC
>Mature Secondary Structure 
PMLSIRKRPAHRLPLTLAAALLTGCTLVSGAALAESTLRIGMTAADIPRTLGQPDQGFE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHCCCCCCCC
GNRFTGLTMYDALVNWDLSSATKPSVLVPGLATEWKVDDADKTKWTFKLRPDVKFHDGSP
CCCEECEEHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCEEECCCCC
FNADAVVWNVDKVLNQSAPQFDASQVGVTASRMPTLVSAKKIDDLTVELVTKEPDSFLPY
CCCCEEEEEHHHHHCCCCCCCCCHHCCCCHHHCCHHHHHHCCCCEEEEEEECCCCCCCCC
NITNLFMASPTQWKKFFDAAEGADAKAKSQAAWAAFAKDASGTGPWKMSKFVPRERLELV
CHHHEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHH
KNTDYWDKGRVPKTDKMVLLPMPEANARTAALLAGQVDWIEAPAPDALPQLRQRGFMIRS
HCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCEECCCCCHHHHHHHHCCEEEEC
NEQPHVWPWQFSRVEGSPWNDIRVRKAANLCVDREGMRDGLLGGLMAPATGTVEPGHPWR
CCCCCCCCCEEECCCCCCCCCEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
GNPTFQIKYDPEAGKKLMQEAGFGPSKKLTVKIQTSASGSGQMLPLPMNEYLQQALAECY
CCCEEEEEECCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEECCHHHHHHHHHHHHE
FDVQLDVIEWNTLFTNWRRGAKDPSANGSNAINVTYAAMDPFFALVRFLQSGMAPPTSNN
EEEEEEEEECHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCC
WGFINNPKFDELVKKARSTFDPAARDAALAELHAASVDDAAFLYVAHDVGPRALSPKVSG
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHC
LVQPKSWFVDFSPVVVAP
EECCHHEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]