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The map label for this gene is pcaR [H]

Identifier: 158423112

GI number: 158423112

Start: 1688903

End: 1689772

Strand: Reverse

Name: pcaR [H]

Synonym: AZC_1488

Alternate gene names: 158423112

Gene position: 1689772-1688903 (Counterclockwise)

Preceding gene: 158423116

Following gene: 158423110

Centisome position: 31.47

GC content: 65.86

Gene sequence:

>870_bases
TTGCATTACGATCTAGCGTATTGCATAGTAATACTTAAAATCGTACCGGGAGAGACGCGTATGTCAACTGACAGGGGAAA
CGACGTGCAGCGCGATCCGCTCCACGTCTCATCGGTTGCAAAGACGTTTCGGGTCCTGGAAGCCTTCGGGCAGACGACCG
GCGATCTGAGCCTTGCCGAACTCGCCCAGCACGCGGAACTCGACAAGAGCGCCACCCAGCGCTTCGCCCATACGCTCTGG
CAGCTCGGCTATCTGGAGAAGGACGCCCGCACGCGCCGCTTCCGCCTCGGAAAGCCGGTGCTCGACCTCACCTATTTCTA
CCTGCGCTCCAACCCTCTGGTGGAGCGCGCCACGCCCGCGCTGCTGGACCTGCGCCAGCGCAGCGGCGAGCGGGCCAATC
TCTCGCTCTATGACCAGACCACGATGATCTACGTCATCCGTCACCAGTCCAAGCGCGAATATTACGACAGCTCGCTCATC
GGCCGCCGCGTACCGGTCTATTGCTCAGCAGGCGGTCGGGCCATCCTCGCGCGCCTCTCGCCGGCGGACGCGGCAGACGT
CATCGCGCGCTCGAACATCGTCGCCCGCACCCCGCACACGCTCACCGACCGCGCGGCCATTCTCGCCAAGGTGGAGGAGA
CGCGCGCCGCCGGCTACGGCCTGGCGGTGGAGGAGACGGAGATCGGCGAGATTACCCTCGGTGCTGCCGTCACCGATGCG
CTGGGACGGCCGGTCGCGGCCGTTCACATCGCCGCTTCGGTCAAGGAATGGGCGCCGGAGGCCTTCGCGGAGCGCTTCGC
CCATATGGTGATCGAGACGGCACAGGCCCTGAGCAGCACGCGGGACCATCTGCGGCCCCGCGCCCGCTGA

Upstream 100 bases:

>100_bases
CTTCACCTTCGGGCGCGGCGGCACCCTGCCCCGAGCGCGCAAGCGTCTTTGCCATGATGGACCCCTCTGCTTGTTATTGC
CGGTGCGTGCGCACCACTAA

Downstream 100 bases:

>100_bases
GGGGGCGACGGCGCGGTCCTGTCCGCGCCGGACCCCGGTCAGCCGCCGGTGCGCCGTGCCGGCTGGCGGCCGTTGGCGGC
GATGGGCGGGCGCGGCAGGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MHYDLAYCIVILKIVPGETRMSTDRGNDVQRDPLHVSSVAKTFRVLEAFGQTTGDLSLAELAQHAELDKSATQRFAHTLW
QLGYLEKDARTRRFRLGKPVLDLTYFYLRSNPLVERATPALLDLRQRSGERANLSLYDQTTMIYVIRHQSKREYYDSSLI
GRRVPVYCSAGGRAILARLSPADAADVIARSNIVARTPHTLTDRAAILAKVEETRAAGYGLAVEETEIGEITLGAAVTDA
LGRPVAAVHIAASVKEWAPEAFAERFAHMVIETAQALSSTRDHLRPRAR

Sequences:

>Translated_289_residues
MHYDLAYCIVILKIVPGETRMSTDRGNDVQRDPLHVSSVAKTFRVLEAFGQTTGDLSLAELAQHAELDKSATQRFAHTLW
QLGYLEKDARTRRFRLGKPVLDLTYFYLRSNPLVERATPALLDLRQRSGERANLSLYDQTTMIYVIRHQSKREYYDSSLI
GRRVPVYCSAGGRAILARLSPADAADVIARSNIVARTPHTLTDRAAILAKVEETRAAGYGLAVEETEIGEITLGAAVTDA
LGRPVAAVHIAASVKEWAPEAFAERFAHMVIETAQALSSTRDHLRPRAR
>Mature_289_residues
MHYDLAYCIVILKIVPGETRMSTDRGNDVQRDPLHVSSVAKTFRVLEAFGQTTGDLSLAELAQHAELDKSATQRFAHTLW
QLGYLEKDARTRRFRLGKPVLDLTYFYLRSNPLVERATPALLDLRQRSGERANLSLYDQTTMIYVIRHQSKREYYDSSLI
GRRVPVYCSAGGRAILARLSPADAADVIARSNIVARTPHTLTDRAAILAKVEETRAAGYGLAVEETEIGEITLGAAVTDA
LGRPVAAVHIAASVKEWAPEAFAERFAHMVIETAQALSSTRDHLRPRAR

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=245, Percent_Identity=28.1632653061224, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788131, Length=242, Percent_Identity=26.8595041322314, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786468, Length=216, Percent_Identity=26.3888888888889, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786715, Length=258, Percent_Identity=22.4806201550388, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789999, Length=256, Percent_Identity=26.5625, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 32113; Mature: 32113

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYDLAYCIVILKIVPGETRMSTDRGNDVQRDPLHVSSVAKTFRVLEAFGQTTGDLSLAE
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
LAQHAELDKSATQRFAHTLWQLGYLEKDARTRRFRLGKPVLDLTYFYLRSNPLVERATPA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHCCHH
LLDLRQRSGERANLSLYDQTTMIYVIRHQSKREYYDSSLIGRRVPVYCSAGGRAILARLS
HHHHHHHCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHCCCCCEEECCCCCEEEEECC
PADAADVIARSNIVARTPHTLTDRAAILAKVEETRAAGYGLAVEETEIGEITLGAAVTDA
CCCHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHHHH
LGRPVAAVHIAASVKEWAPEAFAERFAHMVIETAQALSSTRDHLRPRAR
HCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHYDLAYCIVILKIVPGETRMSTDRGNDVQRDPLHVSSVAKTFRVLEAFGQTTGDLSLAE
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
LAQHAELDKSATQRFAHTLWQLGYLEKDARTRRFRLGKPVLDLTYFYLRSNPLVERATPA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHCCHH
LLDLRQRSGERANLSLYDQTTMIYVIRHQSKREYYDSSLIGRRVPVYCSAGGRAILARLS
HHHHHHHCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHCCCCCEEECCCCCEEEEECC
PADAADVIARSNIVARTPHTLTDRAAILAKVEETRAAGYGLAVEETEIGEITLGAAVTDA
CCCHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHHHH
LGRPVAAVHIAASVKEWAPEAFAERFAHMVIETAQALSSTRDHLRPRAR
HCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]