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The map label for this gene is xerD

Identifier: 15834875

GI number: 15834875

Start: 297547

End: 298452

Strand: Reverse

Name: xerD

Synonym: TC0255

Alternate gene names: 15834875

Gene position: 298452-297547 (Counterclockwise)

Preceding gene: 15834878

Following gene: 15834873

Centisome position: 27.82

GC content: 39.85

Gene sequence:

>906_bases
ATGTCCATGCTTTTCCCCCTTCATCAACAGTTGATAGAACAGTTTACAATCTTTCTTTCTGTCGACCGCGGTATCGCCCC
TCTTTCTGTTCAAGCTTATTGCCAAGATATCCTTCTTTTTTTGCAACGCGTACCCATTGAAACTACAGACATGATCAACC
AAGAGAGTGTTTTTCTTTTTGTAGAAAAATGTCATCAAGCAAAAGAATCAGAAACGACTTTAGCAAGGCGATTGATTGCC
CTAAAAGTGTTCTTCCATTTCCTAAAAGACGCTAAGCTTATCCATCAGCAGCCTTTCATAGAACATCCTAAAGTCTGGAA
AAGGCTTCCTTCTATTCTTTCAACAGAAGAAGTCAACTCCCTACTGAATCAGCCGCTTAATACTCTGAATTTAGATGCTT
ATATAGCAAACAGAGATACGGCTATCCTTTATACATTTTATGCTACAGGAATTCGTGTATCCGAACTCTGTGATCTTTGT
ATTGGAGATATCAGTGATGATTTTATTCGTGTGACTGGAAAGGGCAGGAAAACTCGTCTCGTTCCTATTAGTATCAAAGC
ACGACAGACTATTGATTCGTACTTGACCATGTTTAGAGAAAGATTTCAAAAGAAAAATCCCTCTGAAGAACATGTATTTT
TGTCCATCAGAGGGAAAAAATTAGAACGCTCTTGTGTATGGAAGCGCATTACTTTCTATGCAAAACTCGTCACAACAAAA
CACATCTCACCACACTCTTTGCGGCACGCATTTGCCACACACCTACTCAACAACCAAGCAGATCTCCGAATTATTCAAGA
AATGCTAGGACATGCACGCATCTCTTCCACGGAAATCTACACGCATGTAGCTTCTGAGAGCATTATTGAAAAATTTCACA
CCCATCATCCGAGGAGTAGTTCCTAG

Upstream 100 bases:

>100_bases
TTATTTTAAACAGAGGAAGAACGCATTCTTATATTCTAAAAATGTTTATCCATATAAAAAGTCTGATGATACTTCTTGTT
TTTCAGCTTCAAGTAAAAAG

Downstream 100 bases:

>100_bases
GATCTTCTTCGACGAGAGGTCTGAGAGGTCTTCTTTTTTTTCTCAGCTTTTTTCTTCTTACAAGGGCACTCTAGATTCCT
ATCCGAATCTTCTATAGCTT

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSMLFPLHQQLIEQFTIFLSVDRGIAPLSVQAYCQDILLFLQRVPIETTDMINQESVFLFVEKCHQAKESETTLARRLIA
LKVFFHFLKDAKLIHQQPFIEHPKVWKRLPSILSTEEVNSLLNQPLNTLNLDAYIANRDTAILYTFYATGIRVSELCDLC
IGDISDDFIRVTGKGRKTRLVPISIKARQTIDSYLTMFRERFQKKNPSEEHVFLSIRGKKLERSCVWKRITFYAKLVTTK
HISPHSLRHAFATHLLNNQADLRIIQEMLGHARISSTEIYTHVASESIIEKFHTHHPRSSS

Sequences:

>Translated_301_residues
MSMLFPLHQQLIEQFTIFLSVDRGIAPLSVQAYCQDILLFLQRVPIETTDMINQESVFLFVEKCHQAKESETTLARRLIA
LKVFFHFLKDAKLIHQQPFIEHPKVWKRLPSILSTEEVNSLLNQPLNTLNLDAYIANRDTAILYTFYATGIRVSELCDLC
IGDISDDFIRVTGKGRKTRLVPISIKARQTIDSYLTMFRERFQKKNPSEEHVFLSIRGKKLERSCVWKRITFYAKLVTTK
HISPHSLRHAFATHLLNNQADLRIIQEMLGHARISSTEIYTHVASESIIEKFHTHHPRSSS
>Mature_300_residues
SMLFPLHQQLIEQFTIFLSVDRGIAPLSVQAYCQDILLFLQRVPIETTDMINQESVFLFVEKCHQAKESETTLARRLIAL
KVFFHFLKDAKLIHQQPFIEHPKVWKRLPSILSTEEVNSLLNQPLNTLNLDAYIANRDTAILYTFYATGIRVSELCDLCI
GDISDDFIRVTGKGRKTRLVPISIKARQTIDSYLTMFRERFQKKNPSEEHVFLSIRGKKLERSCVWKRITFYAKLVTTKH
ISPHSLRHAFATHLLNNQADLRIIQEMLGHARISSTEIYTHVASESIIEKFHTHHPRSSS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=37.3737373737374, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=31.4189189189189, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERD_CHLMU (Q9PL53)

Other databases:

- EMBL:   AE002160
- PIR:   A81724
- RefSeq:   NP_296634.1
- ProteinModelPortal:   Q9PL53
- SMR:   Q9PL53
- GeneID:   1246425
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0255
- TIGR:   TC_0255
- HOGENOM:   HBG727654
- OMA:   RTLAMIC
- ProtClustDB:   PRK00283
- BioCyc:   CMUR243161:TC_0255-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01807
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34888; Mature: 34757

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: ACT_SITE 152-152 ACT_SITE 174-174 ACT_SITE 245-245 ACT_SITE 248-248 ACT_SITE 271-271 ACT_SITE 280-280

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMLFPLHQQLIEQFTIFLSVDRGIAPLSVQAYCQDILLFLQRVPIETTDMINQESVFLF
CCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHH
VEKCHQAKESETTLARRLIALKVFFHFLKDAKLIHQQPFIEHPKVWKRLPSILSTEEVNS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LLNQPLNTLNLDAYIANRDTAILYTFYATGIRVSELCDLCIGDISDDFIRVTGKGRKTRL
HHHCCCCCCCCEEEEECCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCEEEEECCCCEEEE
VPISIKARQTIDSYLTMFRERFQKKNPSEEHVFLSIRGKKLERSCVWKRITFYAKLVTTK
EEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHC
HISPHSLRHAFATHLLNNQADLRIIQEMLGHARISSTEIYTHVASESIIEKFHTHHPRSS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
S
C
>Mature Secondary Structure 
SMLFPLHQQLIEQFTIFLSVDRGIAPLSVQAYCQDILLFLQRVPIETTDMINQESVFLF
CCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHH
VEKCHQAKESETTLARRLIALKVFFHFLKDAKLIHQQPFIEHPKVWKRLPSILSTEEVNS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LLNQPLNTLNLDAYIANRDTAILYTFYATGIRVSELCDLCIGDISDDFIRVTGKGRKTRL
HHHCCCCCCCCEEEEECCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCEEEEECCCCEEEE
VPISIKARQTIDSYLTMFRERFQKKNPSEEHVFLSIRGKKLERSCVWKRITFYAKLVTTK
EEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHC
HISPHSLRHAFATHLLNNQADLRIIQEMLGHARISSTEIYTHVASESIIEKFHTHHPRSS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935