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The map label for this gene is yvrD [H]

Identifier: 158318133

GI number: 158318133

Start: 7765459

End: 7766205

Strand: Reverse

Name: yvrD [H]

Synonym: Franean1_6397

Alternate gene names: 158318133

Gene position: 7766205-7765459 (Counterclockwise)

Preceding gene: 158318135

Following gene: 158318132

Centisome position: 86.46

GC content: 69.08

Gene sequence:

>747_bases
ATGGGCCTCGCGGCGGCGGAGTGTTTCGCCGCGGACGGGGCCAGGGTGGCCGTACTCGCGCGGAACCGGGCAAATCTGGA
GAAGACCATTGGCCGTCTGCTGGAGCTGGGGGCCGCCGACGCCGTGGCCCTGCCCGCGGACATCACCCGCCCCGACGAGG
TGACCGCCGCGTTCGACCTCGTCCGCGACCGGTGGGGGGAACTGAACTCCCTTGTGAACGCTACCGGCCCCAAAGGCGGC
CGGATGGGCCCCTTCGAGGAGCTCACCGACGACGACTGGTTGGCCGCGGTCGACGTCGGCGTGTTGGGTATGGTCCGGTG
TGTGCGGGCCGCGCTGCCCCTGCTGCGCGCCGCCGAGTGGGGCCGCATCGTCAACATCTCCGCGCATTCGACCAAGCGGC
AGACCGCCTCGCTGATCGCGTACACCGCCGCGAAATCGATGGTCACCAGCATCACCAAGAACCTCTCGCTGACCCTGGCT
CCAGACGAGATTCTCGTCAACACCGTGTCTCCGGGAAGCTTTGCCTCCGAGGGTCTGGCCATGTGGGCCCGCGGCATCGG
CATCGACCCGGAGGACCTGCACGCCGTGATGCGCGGCATCACGGAGCATTTCGGCCATCCCGCCCACCTTCCCCGCGCGG
GTGCGCCGCGTGAGATCGGTGCCGTGATCGCCTTCGTCGGCTCGCGCCGGAACACATACATGACCGGCGCGAACGTCAAC
GTCGACGGCGGCTCCGACTTCTCCTGA

Upstream 100 bases:

>100_bases
GTCGCCAAACCCTTTCGGCTGGACGAGGTGGACGGAGGCAACCGAGGTGGATCTTGGCTTAGCCGGTGCCGCGGTGGTGG
TACAGGGCGGTACCCAGGGT

Downstream 100 bases:

>100_bases
CGGACGGGTTCCCGCGGTCAGCCGCGGGTTCGTCGACGCACAGATCCCCAGTCGCCCAGTCGCCCAATCGCATAGCCGCC
TGGGCCCATAGTCACCCGCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MGLAAAECFAADGARVAVLARNRANLEKTIGRLLELGAADAVALPADITRPDEVTAAFDLVRDRWGELNSLVNATGPKGG
RMGPFEELTDDDWLAAVDVGVLGMVRCVRAALPLLRAAEWGRIVNISAHSTKRQTASLIAYTAAKSMVTSITKNLSLTLA
PDEILVNTVSPGSFASEGLAMWARGIGIDPEDLHAVMRGITEHFGHPAHLPRAGAPREIGAVIAFVGSRRNTYMTGANVN
VDGGSDFS

Sequences:

>Translated_248_residues
MGLAAAECFAADGARVAVLARNRANLEKTIGRLLELGAADAVALPADITRPDEVTAAFDLVRDRWGELNSLVNATGPKGG
RMGPFEELTDDDWLAAVDVGVLGMVRCVRAALPLLRAAEWGRIVNISAHSTKRQTASLIAYTAAKSMVTSITKNLSLTLA
PDEILVNTVSPGSFASEGLAMWARGIGIDPEDLHAVMRGITEHFGHPAHLPRAGAPREIGAVIAFVGSRRNTYMTGANVN
VDGGSDFS
>Mature_247_residues
GLAAAECFAADGARVAVLARNRANLEKTIGRLLELGAADAVALPADITRPDEVTAAFDLVRDRWGELNSLVNATGPKGGR
MGPFEELTDDDWLAAVDVGVLGMVRCVRAALPLLRAAEWGRIVNISAHSTKRQTASLIAYTAAKSMVTSITKNLSLTLAP
DEILVNTVSPGSFASEGLAMWARGIGIDPEDLHAVMRGITEHFGHPAHLPRAGAPREIGAVIAFVGSRRNTYMTGANVNV
DGGSDFS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=29.2887029288703, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=25.8196721311475, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=210, Percent_Identity=27.6190476190476, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=29.2682926829268, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788459, Length=189, Percent_Identity=30.1587301587302, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786812, Length=179, Percent_Identity=29.608938547486, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=26.0162601626016, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=24.5901639344262, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=27.0161290322581, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=25.7142857142857, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=26.0162601626016, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.2442748091603, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.6290322580645, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=27.1255060728745, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=25.9541984732824, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=27.4131274131274, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=254, Percent_Identity=28.3464566929134, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=26.5625, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=26.8482490272374, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=26.953125, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=24.904214559387, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=28.3524904214559, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=26.4591439688716, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=27.7992277992278, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=23.7903225806452, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=26.4367816091954, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=28.6885245901639, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=27.4590163934426, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=26.4227642276423, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644337, Length=247, Percent_Identity=26.7206477732794, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=26.7716535433071, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=26.7206477732794, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26127; Mature: 25996

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLAAAECFAADGARVAVLARNRANLEKTIGRLLELGAADAVALPADITRPDEVTAAFDL
CCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHH
VRDRWGELNSLVNATGPKGGRMGPFEELTDDDWLAAVDVGVLGMVRCVRAALPLLRAAEW
HHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRIVNISAHSTKRQTASLIAYTAAKSMVTSITKNLSLTLAPDEILVNTVSPGSFASEGLA
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHEEEECCCCCHHHHHHH
MWARGIGIDPEDLHAVMRGITEHFGHPAHLPRAGAPREIGAVIAFVGSRRNTYMTGANVN
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEE
VDGGSDFS
ECCCCCCC
>Mature Secondary Structure 
GLAAAECFAADGARVAVLARNRANLEKTIGRLLELGAADAVALPADITRPDEVTAAFDL
CCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHH
VRDRWGELNSLVNATGPKGGRMGPFEELTDDDWLAAVDVGVLGMVRCVRAALPLLRAAEW
HHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRIVNISAHSTKRQTASLIAYTAAKSMVTSITKNLSLTLAPDEILVNTVSPGSFASEGLA
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHEEEECCCCCHHHHHHH
MWARGIGIDPEDLHAVMRGITEHFGHPAHLPRAGAPREIGAVIAFVGSRRNTYMTGANVN
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEE
VDGGSDFS
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]