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The map label for this gene is kdsC [H]

Identifier: 157963426

GI number: 157963426

Start: 4404558

End: 4405109

Strand: Direct

Name: kdsC [H]

Synonym: Spea_3612

Alternate gene names: 157963426

Gene position: 4404558-4405109 (Clockwise)

Preceding gene: 157963425

Following gene: 157963427

Centisome position: 85.12

GC content: 46.2

Gene sequence:

>552_bases
ATGTCTCACCAAGGCTTCTACGGCCCGATTAGCGATGATGTTTGGCAAGCGGCAAGCAAGATCAAACTACTGATTTGCGA
TGTTGACGGCGTGTTTTCAGACGGCTTAGTTTATATGAGCAACAGCGGTGAAGAGCTTAAGACCTTCCATACTCGTGACG
GTTATGGTGTACGTTCAGTACTCACTAGCGGCATACAGGTAGCCATTATTACCGGCCGTAAGTCGCAGATCGTCGAAGAC
AGATTTACCGCCCTAGGCGTGACGCATATCTATCAAGGAGTCGATAATAAACTGGCTCCCTATAACGAGTTACTTACACT
TTATAATGTAAGCCCTGAAGAAGTCGCCTATATTGGTGATGATATGGTGGACTTACCGGTTATGCTGAAAGTGGGTCTAT
CAGTATGCGTTGCAGATGGTCACCCTTATGTGAAACAACACGCTAAAATGACCACCCATATTAAAGGCGGTCATGGTGCC
CTTAGAGAGCTAACCGACTTACTACTGTTAAGCCAAGACAAGTTTGACTCGGCCCATGGGATGAGTATATGA

Upstream 100 bases:

>100_bases
GATACTAAGAGCATTAACGGCCTAGTGGTGATTAATGACAAGCAGCAACCTGTCGGCGCATTAAACATGCTCGATATGGT
CAAAGCAGGAGTAATTTAAT

Downstream 100 bases:

>100_bases
ACCGCGTTACCCTAGCGATTATCGCTTTTTTTGGCACTGCACTTCTGCTCTATTGGCAGGTACAGTCTAAGAAAAGCGAA
CAAGAGCTGGATATCGATAT

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSHQGFYGPISDDVWQAASKIKLLICDVDGVFSDGLVYMSNSGEELKTFHTRDGYGVRSVLTSGIQVAIITGRKSQIVED
RFTALGVTHIYQGVDNKLAPYNELLTLYNVSPEEVAYIGDDMVDLPVMLKVGLSVCVADGHPYVKQHAKMTTHIKGGHGA
LRELTDLLLLSQDKFDSAHGMSI

Sequences:

>Translated_183_residues
MSHQGFYGPISDDVWQAASKIKLLICDVDGVFSDGLVYMSNSGEELKTFHTRDGYGVRSVLTSGIQVAIITGRKSQIVED
RFTALGVTHIYQGVDNKLAPYNELLTLYNVSPEEVAYIGDDMVDLPVMLKVGLSVCVADGHPYVKQHAKMTTHIKGGHGA
LRELTDLLLLSQDKFDSAHGMSI
>Mature_182_residues
SHQGFYGPISDDVWQAASKIKLLICDVDGVFSDGLVYMSNSGEELKTFHTRDGYGVRSVLTSGIQVAIITGRKSQIVEDR
FTALGVTHIYQGVDNKLAPYNELLTLYNVSPEEVAYIGDDMVDLPVMLKVGLSVCVADGHPYVKQHAKMTTHIKGGHGAL
RELTDLLLLSQDKFDSAHGMSI

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=160, Percent_Identity=28.125, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI2367202, Length=177, Percent_Identity=60.4519774011299, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20015; Mature: 19884

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQGFYGPISDDVWQAASKIKLLICDVDGVFSDGLVYMSNSGEELKTFHTRDGYGVRSV
CCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCCHHHEEECCCCCCHHHH
LTSGIQVAIITGRKSQIVEDRFTALGVTHIYQGVDNKLAPYNELLTLYNVSPEEVAYIGD
HHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCCHHHEEECCC
DMVDLPVMLKVGLSVCVADGHPYVKQHAKMTTHIKGGHGALRELTDLLLLSQDKFDSAHG
CHHHHHHHHHCCCEEEEECCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCCCCCCCC
MSI
CCC
>Mature Secondary Structure 
SHQGFYGPISDDVWQAASKIKLLICDVDGVFSDGLVYMSNSGEELKTFHTRDGYGVRSV
CCCCCCCCCCHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCCHHHEEECCCCCCHHHH
LTSGIQVAIITGRKSQIVEDRFTALGVTHIYQGVDNKLAPYNELLTLYNVSPEEVAYIGD
HHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCCHHHEEECCC
DMVDLPVMLKVGLSVCVADGHPYVKQHAKMTTHIKGGHGALRELTDLLLLSQDKFDSAHG
CHHHHHHHHHCCCEEEEECCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCCCCCCCC
MSI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]