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The map label for this gene is degQ [H]

Identifier: 157963412

GI number: 157963412

Start: 4390475

End: 4391830

Strand: Direct

Name: degQ [H]

Synonym: Spea_3598

Alternate gene names: 157963412

Gene position: 4390475-4391830 (Clockwise)

Preceding gene: 157963411

Following gene: 157963413

Centisome position: 84.85

GC content: 48.97

Gene sequence:

>1356_bases
ATGAAGACTAAATTATCCTTACTTTCAGCTGCGATATTGAGCGCAACCCTGACACTAGCCCCTGTTGCTTCTCAAGCTGC
AATTCCTTTAGCCGTCGACGGACAAGAGCTACCAAGCTTAGCGCCCATGCTGCAAGAAACAACGCCAGCCGTAGTAGCAG
TTGCAGTCTCTGGAACCCATGTTTCTAAACAGAAGGTCCCCGATGCTTTCCGTTATTTCTTCGGCCCTAACGCTCCACGT
GAACAAGTGCAAGAACGTCCATTTAAAGGGCTAGGTTCAGGGGTCATTATCGATGCCAAAGAAGGTTATATCGTCACTAA
CAACCATGTGATTGAAGGTGCCGATGAGATCCTTATCGGGCTACATGACGGCCGAGAAGTCGAAGCGAAACTAATTGGCA
CTGACGCAGAGTCTGATATCGCTTTATTGCAGATAAAAGCCAAGAATCTGACCGCATTGAAACGCGCCGACTCAGATAAA
CTCCAAGTCGGTGACTTTGCTGTAGCCATTGGAAATCCATTCGGTCTAGGTCAAACAGTTACTTCAGGAATAGTCAGTGC
CATGGGCCGAAGCGGTCTTGGCATCGAGATGCTAGAAAACTTTATTCAAACCGATGCCGCAATCAATAGCGGTAATTCCG
GTGGCGCCTTGGTTAACCTCAATGGTGAGCTTATCGGTATCAATACCGCGATTGTAGCTCCTGGTGGCGGCAACGTCGGT
ATTGGTTTCGCTATCCCTGCCAATATGGTTAATAACCTCGTTAAGCAGATTATTGAACACGGTGAGGTTCGCCGCGGCGT
GCTTGGCGTGATGGGACAAGATCTCACCAGTGAACTCGCCAAAGGTTTCGGTATCGAAACTCAGCACGGCGGCTTTATCA
ACGAAGTGATGCCTGACAGCGCCGCTGCCAAAGCGGGTATAAAAGTCGGTGATATTATTGTCAGCGTTAATGGACGCAGC
ATTAAGAGCTTCCAAGAGCTACGTGCAAAAGTCGCGACTATGGGCGCGGGCACTAAAGTGGAATTTGGTTTAATCCGCGA
TGGCGATGAAGAAACGGTTACCGCAGTACTCGGCGAGTCAACTCAGGCGGCAGAAGCCGCTGCGGGCGCAGTGCATCCTA
TGCTACAAGGGGCGAAGCTGGAAACGGCAAGTTCGTCTGGAGTTGAGATCACAGATGTAGCTCAAGGCTCTCCAGCTGCA
GCAAGTGGCTTAATAAAAGGTGATATTATCGTTGGTGTTAACCGCACTAAGGTGAAAAACCTCAAAGCCCTTAAATCTGC
GCTTGAAGATCAAAAAGGCTCAGTGGCGCTAAAAATTAAGCGAGATAACACTAGCTTGTATTTGATCCTGAGGTAA

Upstream 100 bases:

>100_bases
CTCATTGTTTTTACAATTTTGGTTTTGAAAACTTGGGCTTTGAAACTTGGTTTTCAGACGGTTTTGAAATTTCAGTTTTG
AAAATTGGAGCAACATATAA

Downstream 100 bases:

>100_bases
ACACTCCAATCGTTAAGTAGGAAGCCGAGCAATTTGCTCGGCTCTCTTTTTGGATTTAAAGCGCTTTATCATGATTGCGT
ACAAGCTAGTACAATCATGT

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKTKLSLLSAAILSATLTLAPVASQAAIPLAVDGQELPSLAPMLQETTPAVVAVAVSGTHVSKQKVPDAFRYFFGPNAPR
EQVQERPFKGLGSGVIIDAKEGYIVTNNHVIEGADEILIGLHDGREVEAKLIGTDAESDIALLQIKAKNLTALKRADSDK
LQVGDFAVAIGNPFGLGQTVTSGIVSAMGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
IGFAIPANMVNNLVKQIIEHGEVRRGVLGVMGQDLTSELAKGFGIETQHGGFINEVMPDSAAAKAGIKVGDIIVSVNGRS
IKSFQELRAKVATMGAGTKVEFGLIRDGDEETVTAVLGESTQAAEAAAGAVHPMLQGAKLETASSSGVEITDVAQGSPAA
ASGLIKGDIIVGVNRTKVKNLKALKSALEDQKGSVALKIKRDNTSLYLILR

Sequences:

>Translated_451_residues
MKTKLSLLSAAILSATLTLAPVASQAAIPLAVDGQELPSLAPMLQETTPAVVAVAVSGTHVSKQKVPDAFRYFFGPNAPR
EQVQERPFKGLGSGVIIDAKEGYIVTNNHVIEGADEILIGLHDGREVEAKLIGTDAESDIALLQIKAKNLTALKRADSDK
LQVGDFAVAIGNPFGLGQTVTSGIVSAMGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
IGFAIPANMVNNLVKQIIEHGEVRRGVLGVMGQDLTSELAKGFGIETQHGGFINEVMPDSAAAKAGIKVGDIIVSVNGRS
IKSFQELRAKVATMGAGTKVEFGLIRDGDEETVTAVLGESTQAAEAAAGAVHPMLQGAKLETASSSGVEITDVAQGSPAA
ASGLIKGDIIVGVNRTKVKNLKALKSALEDQKGSVALKIKRDNTSLYLILR
>Mature_451_residues
MKTKLSLLSAAILSATLTLAPVASQAAIPLAVDGQELPSLAPMLQETTPAVVAVAVSGTHVSKQKVPDAFRYFFGPNAPR
EQVQERPFKGLGSGVIIDAKEGYIVTNNHVIEGADEILIGLHDGREVEAKLIGTDAESDIALLQIKAKNLTALKRADSDK
LQVGDFAVAIGNPFGLGQTVTSGIVSAMGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
IGFAIPANMVNNLVKQIIEHGEVRRGVLGVMGQDLTSELAKGFGIETQHGGFINEVMPDSAAAKAGIKVGDIIVSVNGRS
IKSFQELRAKVATMGAGTKVEFGLIRDGDEETVTAVLGESTQAAEAAAGAVHPMLQGAKLETASSSGVEITDVAQGSPAA
ASGLIKGDIIVGVNRTKVKNLKALKSALEDQKGSVALKIKRDNTSLYLILR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=285, Percent_Identity=37.1929824561403, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI22129776, Length=312, Percent_Identity=35.2564102564103, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI7019477, Length=314, Percent_Identity=33.4394904458599, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI24308541, Length=247, Percent_Identity=34.0080971659919, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI1789629, Length=458, Percent_Identity=54.585152838428, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1786356, Length=452, Percent_Identity=51.5486725663717, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1789630, Length=276, Percent_Identity=43.4782608695652, Blast_Score=207, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24646839, Length=253, Percent_Identity=34.3873517786561, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 46506; Mature: 46506

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKLSLLSAAILSATLTLAPVASQAAIPLAVDGQELPSLAPMLQETTPAVVAVAVSGTH
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHCCHHHHHHHCCCCEEEEEEECCCC
VSKQKVPDAFRYFFGPNAPREQVQERPFKGLGSGVIIDAKEGYIVTNNHVIEGADEILIG
CCHHHCCHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCEEECCCCEEEEE
LHDGREVEAKLIGTDAESDIALLQIKAKNLTALKRADSDKLQVGDFAVAIGNPFGLGQTV
ECCCCEEEEEEEECCCCCCEEEEEEECCCCHHHHHCCCCCEEECCEEEEECCCCCCCHHH
TSGIVSAMGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEEEECCCCCEE
IGFAIPANMVNNLVKQIIEHGEVRRGVLGVMGQDLTSELAKGFGIETQHGGFINEVMPDS
EEEECCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHCCCC
AAAKAGIKVGDIIVSVNGRSIKSFQELRAKVATMGAGTKVEFGLIRDGDEETVTAVLGES
HHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCC
TQAAEAAAGAVHPMLQGAKLETASSSGVEITDVAQGSPAAASGLIKGDIIVGVNRTKVKN
CHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCHHHCCCEECCEEEECCHHHHHH
LKALKSALEDQKGSVALKIKRDNTSLYLILR
HHHHHHHHHCCCCCEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MKTKLSLLSAAILSATLTLAPVASQAAIPLAVDGQELPSLAPMLQETTPAVVAVAVSGTH
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHCCHHHHHHHCCCCEEEEEEECCCC
VSKQKVPDAFRYFFGPNAPREQVQERPFKGLGSGVIIDAKEGYIVTNNHVIEGADEILIG
CCHHHCCHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEECCCCEEEECCEEECCCCEEEEE
LHDGREVEAKLIGTDAESDIALLQIKAKNLTALKRADSDKLQVGDFAVAIGNPFGLGQTV
ECCCCEEEEEEEECCCCCCEEEEEEECCCCHHHHHCCCCCEEECCEEEEECCCCCCCHHH
TSGIVSAMGRSGLGIEMLENFIQTDAAINSGNSGGALVNLNGELIGINTAIVAPGGGNVG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEEEECCCCCEE
IGFAIPANMVNNLVKQIIEHGEVRRGVLGVMGQDLTSELAKGFGIETQHGGFINEVMPDS
EEEECCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHCCCC
AAAKAGIKVGDIIVSVNGRSIKSFQELRAKVATMGAGTKVEFGLIRDGDEETVTAVLGES
HHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCC
TQAAEAAAGAVHPMLQGAKLETASSSGVEITDVAQGSPAAASGLIKGDIIVGVNRTKVKN
CHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCHHHCCCEECCEEEECCHHHHHH
LKALKSALEDQKGSVALKIKRDNTSLYLILR
HHHHHHHHHCCCCCEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]