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The map label for this gene is tolC [H]

Identifier: 157963377

GI number: 157963377

Start: 4350531

End: 4351835

Strand: Direct

Name: tolC [H]

Synonym: Spea_3563

Alternate gene names: 157963377

Gene position: 4350531-4351835 (Clockwise)

Preceding gene: 157963369

Following gene: 157963381

Centisome position: 84.08

GC content: 45.67

Gene sequence:

>1305_bases
ATGAAATTCAAGATCCGTTCTCTATGTGCCGCATTAACCCTTGCAGCAACAACGCAAGTAGCTCATGCCGATGACCTTCT
ACAAATATATCAACAAGCATTGACCAGCGATCCAATTGCGCTACAAGCTAAAGCTCAACGCGATGCCTTGTATGAACAGA
TTGAAGAAAATCGTGCGCCACTACTGCCTACTATCAGTGCTAATATCGGTTACGATAAAGCTTGGAATGATCCAAGCGAA
GACAGCAGCGGTATTGTTGGCGGCGTAACGCTTAATCAGGTCATTTACGATCACAGCGCGTGGGTAGGCTTAAGCCTAGC
AGAAAAAGCAGCTTCTCAAGCAGACTCGGCATACGCCTCTGCATTACAGAGCCTGATTATCCGTGTAACCAATGCTTACT
TTGACGTGCTAACAGCCAAAGATAACTACGAGTTCCAAGGTTCAGAGAAACGTGCAATTGAGCGTCAGCTTGAGCAGACT
AAGCAACGTTTTGCTGTAGGTCTTACTGCGATTACCGACGTACATGAAGCGCAAGCGCAATATGACTTGGCTAACGCGAC
AGAGATCTTAGCCGAAAACACACTAGCGAACAGCTACGAAGCATTACGTGAAATCACGGGTATCGATCACAAGAGCATCA
ATATCCTTGATACTAACCGTTTCTCAGCAACATCGGTTGCACCAGCGTCTTCATCTGAGTGGATCAAGATGGCTGAAACC
AACAGTGTTGACCTGATGACCACGCGTATCGGTAAAGATATCGCCGAAGAGACCATTACGCTTTATAAAGCTGGCCACAT
GCCATCGCTAAGCTTAAATGCCGGCTATAACAAAGGTATTGAGCAAGAGCCAGGAAACGACTTTGATAACGGCACTGTAG
GCGTCACCCTAAGCATTCCTATCTTTGAAGGCTTCAAGGTTTCTTCTCGTGTAAATCAGGCGCAATACCAATACGTAGAA
GCAAGCGAGAAGCTTGAACAGACTCACCGCCAAGTAGTTAAAAATGTTCGTAATAACTTTAACAACGTCGGTGCATCTAT
CAGCTCAATCCGTGCTTATGAGCAGTCAGTGATCTCTTCAGAGAGCGCATTGAAAGCGACTCAGGCTGGTTTTGAAGTGG
GTACACGTACCATTGTTGACGTATTAAACCGTACACGTGACCTATACGATTCAAAGCGTAAGCTGTCTGATGCACGTTAT
GGCTACATCAATTCAATCCTAGCGCTTAAACAAGCTGCGGGTACATTGAACGAAGATGATGTTGCCTCAATTAACAACGG
CCTTGTAGCTCCAACTGCTAACTAA

Upstream 100 bases:

>100_bases
CGCAAACCGCCTTACTGCCTATGAGAAATTGTAAGGCAAGGCTAAACATAACAAGTTAAATTCGCTCCTCAATGGAGAAT
TTTGTCTAAAAGGACAGCAA

Downstream 100 bases:

>100_bases
TCCCTGTTGTTAACGCTATAAAAAAACCGCCAAATGGCGGTTTTTTTATAGTTCATAATTACTACTAATAGCAGCGACTA
ACGAGAGCCGCTACTATTAA

Product: outer membrane channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFKIRSLCAALTLAATTQVAHADDLLQIYQQALTSDPIALQAKAQRDALYEQIEENRAPLLPTISANIGYDKAWNDPSE
DSSGIVGGVTLNQVIYDHSAWVGLSLAEKAASQADSAYASALQSLIIRVTNAYFDVLTAKDNYEFQGSEKRAIERQLEQT
KQRFAVGLTAITDVHEAQAQYDLANATEILAENTLANSYEALREITGIDHKSINILDTNRFSATSVAPASSSEWIKMAET
NSVDLMTTRIGKDIAEETITLYKAGHMPSLSLNAGYNKGIEQEPGNDFDNGTVGVTLSIPIFEGFKVSSRVNQAQYQYVE
ASEKLEQTHRQVVKNVRNNFNNVGASISSIRAYEQSVISSESALKATQAGFEVGTRTIVDVLNRTRDLYDSKRKLSDARY
GYINSILALKQAAGTLNEDDVASINNGLVAPTAN

Sequences:

>Translated_434_residues
MKFKIRSLCAALTLAATTQVAHADDLLQIYQQALTSDPIALQAKAQRDALYEQIEENRAPLLPTISANIGYDKAWNDPSE
DSSGIVGGVTLNQVIYDHSAWVGLSLAEKAASQADSAYASALQSLIIRVTNAYFDVLTAKDNYEFQGSEKRAIERQLEQT
KQRFAVGLTAITDVHEAQAQYDLANATEILAENTLANSYEALREITGIDHKSINILDTNRFSATSVAPASSSEWIKMAET
NSVDLMTTRIGKDIAEETITLYKAGHMPSLSLNAGYNKGIEQEPGNDFDNGTVGVTLSIPIFEGFKVSSRVNQAQYQYVE
ASEKLEQTHRQVVKNVRNNFNNVGASISSIRAYEQSVISSESALKATQAGFEVGTRTIVDVLNRTRDLYDSKRKLSDARY
GYINSILALKQAAGTLNEDDVASINNGLVAPTAN
>Mature_434_residues
MKFKIRSLCAALTLAATTQVAHADDLLQIYQQALTSDPIALQAKAQRDALYEQIEENRAPLLPTISANIGYDKAWNDPSE
DSSGIVGGVTLNQVIYDHSAWVGLSLAEKAASQADSAYASALQSLIIRVTNAYFDVLTAKDNYEFQGSEKRAIERQLEQT
KQRFAVGLTAITDVHEAQAQYDLANATEILAENTLANSYEALREITGIDHKSINILDTNRFSATSVAPASSSEWIKMAET
NSVDLMTTRIGKDIAEETITLYKAGHMPSLSLNAGYNKGIEQEPGNDFDNGTVGVTLSIPIFEGFKVSSRVNQAQYQYVE
ASEKLEQTHRQVVKNVRNNFNNVGASISSIRAYEQSVISSESALKATQAGFEVGTRTIVDVLNRTRDLYDSKRKLSDARY
GYINSILALKQAAGTLNEDDVASINNGLVAPTAN

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=432, Percent_Identity=42.8240740740741, Blast_Score=327, Evalue=7e-91,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47348; Mature: 47348

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKIRSLCAALTLAATTQVAHADDLLQIYQQALTSDPIALQAKAQRDALYEQIEENRAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCC
LLPTISANIGYDKAWNDPSEDSSGIVGGVTLNQVIYDHSAWVGLSLAEKAASQADSAYAS
CCCEEECCCCCCCCCCCCCCCCCCEEECEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ALQSLIIRVTNAYFDVLTAKDNYEFQGSEKRAIERQLEQTKQRFAVGLTAITDVHEAQAQ
HHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDLANATEILAENTLANSYEALREITGIDHKSINILDTNRFSATSVAPASSSEWIKMAET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECC
NSVDLMTTRIGKDIAEETITLYKAGHMPSLSLNAGYNKGIEQEPGNDFDNGTVGVTLSIP
CCCEEHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEE
IFEGFKVSSRVNQAQYQYVEASEKLEQTHRQVVKNVRNNFNNVGASISSIRAYEQSVISS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
ESALKATQAGFEVGTRTIVDVLNRTRDLYDSKRKLSDARYGYINSILALKQAAGTLNEDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VASINNGLVAPTAN
HHHHCCCEECCCCC
>Mature Secondary Structure
MKFKIRSLCAALTLAATTQVAHADDLLQIYQQALTSDPIALQAKAQRDALYEQIEENRAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCC
LLPTISANIGYDKAWNDPSEDSSGIVGGVTLNQVIYDHSAWVGLSLAEKAASQADSAYAS
CCCEEECCCCCCCCCCCCCCCCCCEEECEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ALQSLIIRVTNAYFDVLTAKDNYEFQGSEKRAIERQLEQTKQRFAVGLTAITDVHEAQAQ
HHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDLANATEILAENTLANSYEALREITGIDHKSINILDTNRFSATSVAPASSSEWIKMAET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECC
NSVDLMTTRIGKDIAEETITLYKAGHMPSLSLNAGYNKGIEQEPGNDFDNGTVGVTLSIP
CCCEEHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEE
IFEGFKVSSRVNQAQYQYVEASEKLEQTHRQVVKNVRNNFNNVGASISSIRAYEQSVISS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
ESALKATQAGFEVGTRTIVDVLNRTRDLYDSKRKLSDARYGYINSILALKQAAGTLNEDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VASINNGLVAPTAN
HHHHCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]