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The map label for this gene is yheS [H]

Identifier: 157963315

GI number: 157963315

Start: 4279723

End: 4281693

Strand: Direct

Name: yheS [H]

Synonym: Spea_3501

Alternate gene names: 157963315

Gene position: 4279723-4281693 (Clockwise)

Preceding gene: 157963311

Following gene: 157963316

Centisome position: 82.71

GC content: 48.05

Gene sequence:

>1971_bases
ATGTTGCTATGCCTTCTAGGCTATTATCCCTGCCAATATTTACTGTGTAAGCCGACTTCAATGATCACCATCTCTCAAGC
TCAACTCGTTCGTGGCTCGAAAACCTTGCTCGATGAAACTTCATTAACCGTCTATCCAGGCCACAAGGTCGGTCTCGTTG
GAGCAAACGGCAGCGGCAAGTCTTCATTGCTTGCGCTTATCTTGGGCAAAATCAGCCTAGATAAAGGTGAATTTACTATG
CCTAGCGGTTGGCAGATGGCCACTGTGGCACAGGAAACACCTGCACTTGACGTATCGGCAATTGAATATGTGATCGATGG
CGATAGCGAATACCGCGAACTTGAAGCCGAGTTACATGCAGCCCAAGAAGCCGACGATGGTCATAAGATTGCCCTATTGC
ATGGCAAAATTGATGCTATTGGCGGCTATGCCATTCATTCTCGCGCCGCAAGCTTACTTGCCGGCCTAGGTTTTAGCGAG
CAAGAGCAAAGCAATCCAGTGAAGAGTTTCTCGGGTGGTTGGCGCATGCGTCTTAACTTAGCCCAAGCTCTGTTATGTCG
CTCAGATCTACTACTTCTCGATGAGCCAACTAACCACTTGGACTTAGACACCATGTACTGGTTAGAGGGCTGGATTAAAG
CCTATCAAGGCACGCTTATTCTGATCAGTCACGACCGCGACTTTATCGATGGTATCGTCGATGAAATCGTTCATGTCGAA
AACACAAAACTGAACTACTACAAGGGTAACTACACCTCGTTTGAGCGTGTTCGTGCCGAGCGTATGGCGCAGCAACAAGT
CGCCTTTGAGCGTCAACAAAAAGAGCGCGCCCATATGCAATCTTTTGTTGACCGTTTCCGCTATAAAGCCAGTAAAGCCA
AGCAGGCTCAAAGTCGCTTAAAAGCGCTTGAGCGTATGGCTGAGCTACTGCCATCACAAGCCGACAGCCCATTCCATATG
GCATTTAGAGAACCTGAAGCCTTGCCAAATCCACTGGTGACAATGGAGCAGGTTTCTATCGGTTACGGTGAAACCGAAAT
CCTTAAGAAAGTTCATCTCAACCTAGTTCCCGGTGCTCGTATCGGTTTGCTAGGTCGCAATGGTGCGGGTAAGTCGACCT
TAGTAAAACTGCTCTCTGGCGAGCTCTCGCCGATGAAAGGTCAGTATGAAACAAATCCGGGCTTAAACATCGGATATTTT
GCTCAGCATCAGCTGGAATTTTTAAGCTTAGATGACTCACCGCTGCAGCATATGGTGCGCCTAGCCCCAACAACTAAAGA
GCAGGAACTACGTAACTTCTTAGGCGGTTACGGTTTTAACGGCGATATGGCATTGTCACCGGTTCGCCCCTTCTCTGGTG
GTGAAAAGGCACGTTTAGTACTGGCATTGCTTGTATGGCAACGCCCAAACCTATTGCTACTCGATGAACCAACTAACCAC
TTAGATCTAGAGATGCGTCATGCGTTAACCATGGCTCTACAGACCTTTGAAGGTGCAATGATTATCGTCTCGCACGATAG
ACATCTATTGCGCTTAAGCTGCAGTGATTACTATCTCGTCGACCAGGGGGAAGTAAAAAGCTTCGACGGCGACCTAGATG
ATTATCATCAGTGGTTGCTCGATGCAGCTAAGACCGCTGGCAAGTCGGAAGAGACTGAGACTGGCAAGCCAGTTCAAGAC
AAGAAGCTACAGAAACGCTTGGATGCAGAGCTAAGACAGAAGCTGTCACCACTTAAGAAGGTGCAGACTAAACTTGAAAA
AGAACAGCATAAAGCTAACGAGCGCCTAAAAGAGCTTGAAGATATGCTGGCCGATACTAGCCTTTATGATGCCGATAACA
AGGCTAAACTCACCCAAGTACTCACTGAGCGTACAACGCTGACTCAAGGGTTAGAGGAGAGTGAAATGGAGTGGCTAGAA
ATCCAAGAAGAGATCGAAACCATAGAGCAAAGCGTTCGCGCCGAAGCCTAG

Upstream 100 bases:

>100_bases
TTTTAGTTGTTGTAGTCATGATTTTACTTCCAGTCCATATATGTCTAACATTTTGCCACAAAAGCTGCGCTATGACCGTA
TTTTTCCCCGATGTGCGTAG

Downstream 100 bases:

>100_bases
CTTAGATTTCAGTTTAAGTCGGAGTTCGAGCCAAAGTTCGAGCCAAAGTTTTAGGCTGAATTAGACAAATGGGGAGCACG
GCTCCCCATTTTGTTATCAT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MLLCLLGYYPCQYLLCKPTSMITISQAQLVRGSKTLLDETSLTVYPGHKVGLVGANGSGKSSLLALILGKISLDKGEFTM
PSGWQMATVAQETPALDVSAIEYVIDGDSEYRELEAELHAAQEADDGHKIALLHGKIDAIGGYAIHSRAASLLAGLGFSE
QEQSNPVKSFSGGWRMRLNLAQALLCRSDLLLLDEPTNHLDLDTMYWLEGWIKAYQGTLILISHDRDFIDGIVDEIVHVE
NTKLNYYKGNYTSFERVRAERMAQQQVAFERQQKERAHMQSFVDRFRYKASKAKQAQSRLKALERMAELLPSQADSPFHM
AFREPEALPNPLVTMEQVSIGYGETEILKKVHLNLVPGARIGLLGRNGAGKSTLVKLLSGELSPMKGQYETNPGLNIGYF
AQHQLEFLSLDDSPLQHMVRLAPTTKEQELRNFLGGYGFNGDMALSPVRPFSGGEKARLVLALLVWQRPNLLLLDEPTNH
LDLEMRHALTMALQTFEGAMIIVSHDRHLLRLSCSDYYLVDQGEVKSFDGDLDDYHQWLLDAAKTAGKSEETETGKPVQD
KKLQKRLDAELRQKLSPLKKVQTKLEKEQHKANERLKELEDMLADTSLYDADNKAKLTQVLTERTTLTQGLEESEMEWLE
IQEEIETIEQSVRAEA

Sequences:

>Translated_656_residues
MLLCLLGYYPCQYLLCKPTSMITISQAQLVRGSKTLLDETSLTVYPGHKVGLVGANGSGKSSLLALILGKISLDKGEFTM
PSGWQMATVAQETPALDVSAIEYVIDGDSEYRELEAELHAAQEADDGHKIALLHGKIDAIGGYAIHSRAASLLAGLGFSE
QEQSNPVKSFSGGWRMRLNLAQALLCRSDLLLLDEPTNHLDLDTMYWLEGWIKAYQGTLILISHDRDFIDGIVDEIVHVE
NTKLNYYKGNYTSFERVRAERMAQQQVAFERQQKERAHMQSFVDRFRYKASKAKQAQSRLKALERMAELLPSQADSPFHM
AFREPEALPNPLVTMEQVSIGYGETEILKKVHLNLVPGARIGLLGRNGAGKSTLVKLLSGELSPMKGQYETNPGLNIGYF
AQHQLEFLSLDDSPLQHMVRLAPTTKEQELRNFLGGYGFNGDMALSPVRPFSGGEKARLVLALLVWQRPNLLLLDEPTNH
LDLEMRHALTMALQTFEGAMIIVSHDRHLLRLSCSDYYLVDQGEVKSFDGDLDDYHQWLLDAAKTAGKSEETETGKPVQD
KKLQKRLDAELRQKLSPLKKVQTKLEKEQHKANERLKELEDMLADTSLYDADNKAKLTQVLTERTTLTQGLEESEMEWLE
IQEEIETIEQSVRAEA
>Mature_656_residues
MLLCLLGYYPCQYLLCKPTSMITISQAQLVRGSKTLLDETSLTVYPGHKVGLVGANGSGKSSLLALILGKISLDKGEFTM
PSGWQMATVAQETPALDVSAIEYVIDGDSEYRELEAELHAAQEADDGHKIALLHGKIDAIGGYAIHSRAASLLAGLGFSE
QEQSNPVKSFSGGWRMRLNLAQALLCRSDLLLLDEPTNHLDLDTMYWLEGWIKAYQGTLILISHDRDFIDGIVDEIVHVE
NTKLNYYKGNYTSFERVRAERMAQQQVAFERQQKERAHMQSFVDRFRYKASKAKQAQSRLKALERMAELLPSQADSPFHM
AFREPEALPNPLVTMEQVSIGYGETEILKKVHLNLVPGARIGLLGRNGAGKSTLVKLLSGELSPMKGQYETNPGLNIGYF
AQHQLEFLSLDDSPLQHMVRLAPTTKEQELRNFLGGYGFNGDMALSPVRPFSGGEKARLVLALLVWQRPNLLLLDEPTNH
LDLEMRHALTMALQTFEGAMIIVSHDRHLLRLSCSDYYLVDQGEVKSFDGDLDDYHQWLLDAAKTAGKSEETETGKPVQD
KKLQKRLDAELRQKLSPLKKVQTKLEKEQHKANERLKELEDMLADTSLYDADNKAKLTQVLTERTTLTQGLEESEMEWLE
IQEEIETIEQSVRAEA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=37.3134328358209, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI10947137, Length=526, Percent_Identity=37.8326996197719, Blast_Score=339, Evalue=6e-93,
Organism=Homo sapiens, GI27881506, Length=526, Percent_Identity=37.8326996197719, Blast_Score=338, Evalue=8e-93,
Organism=Homo sapiens, GI10947135, Length=544, Percent_Identity=32.3529411764706, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI69354671, Length=544, Percent_Identity=32.3529411764706, Blast_Score=260, Evalue=2e-69,
Organism=Escherichia coli, GI1789751, Length=630, Percent_Identity=60.6349206349206, Blast_Score=795, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=527, Percent_Identity=34.3453510436433, Blast_Score=298, Evalue=9e-82,
Organism=Escherichia coli, GI1787182, Length=643, Percent_Identity=28.4603421461897, Blast_Score=229, Evalue=6e-61,
Organism=Escherichia coli, GI2367384, Length=538, Percent_Identity=29.7397769516729, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI1788165, Length=208, Percent_Identity=35.0961538461538, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788506, Length=561, Percent_Identity=22.6381461675579, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=38.8679245283019, Blast_Score=386, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17555318, Length=518, Percent_Identity=37.4517374517375, Blast_Score=343, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17559834, Length=551, Percent_Identity=33.9382940108893, Blast_Score=312, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6321121, Length=541, Percent_Identity=37.1534195933457, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320874, Length=530, Percent_Identity=32.6415094339623, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6325030, Length=394, Percent_Identity=30.7106598984772, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324314, Length=602, Percent_Identity=26.7441860465116, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323278, Length=571, Percent_Identity=27.1453590192644, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=38.5199240986717, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24642252, Length=545, Percent_Identity=37.6146788990826, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI18859989, Length=545, Percent_Identity=37.6146788990826, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24641342, Length=545, Percent_Identity=33.7614678899083, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI24648279, Length=254, Percent_Identity=24.8031496062992, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73616; Mature: 73616

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLCLLGYYPCQYLLCKPTSMITISQAQLVRGSKTLLDETSLTVYPGHKVGLVGANGSGK
CEEEEEECCCHHEEEECCCCEEEECHHHHHCCCHHHHCCCCEEEECCCEEEEEECCCCCH
SSLLALILGKISLDKGEFTMPSGWQMATVAQETPALDVSAIEYVIDGDSEYRELEAELHA
HHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCHHHEEEEECCCHHHHHHHHHHHH
AQEADDGHKIALLHGKIDAIGGYAIHSRAASLLAGLGFSEQEQSNPVKSFSGGWRMRLNL
HHCCCCCCEEEEEECCEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCCEEEHHH
AQALLCRSDLLLLDEPTNHLDLDTMYWLEGWIKAYQGTLILISHDRDFIDGIVDEIVHVE
HHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHC
NTKLNYYKGNYTSFERVRAERMAQQQVAFERQQKERAHMQSFVDRFRYKASKAKQAQSRL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALERMAELLPSQADSPFHMAFREPEALPNPLVTMEQVSIGYGETEILKKVHLNLVPGAR
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEHHHHHCCCCHHHHHHHHHHEECCCCE
IGLLGRNGAGKSTLVKLLSGELSPMKGQYETNPGLNIGYFAQHQLEFLSLDDSPLQHMVR
EEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHCCEEEEECCCHHHHHHHH
LAPTTKEQELRNFLGGYGFNGDMALSPVRPFSGGEKARLVLALLVWQRPNLLLLDEPTNH
HCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCC
LDLEMRHALTMALQTFEGAMIIVSHDRHLLRLSCSDYYLVDQGEVKSFDGDLDDYHQWLL
CCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHH
DAAKTAGKSEETETGKPVQDKKLQKRLDAELRQKLSPLKKVQTKLEKEQHKANERLKELE
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLADTSLYDADNKAKLTQVLTERTTLTQGLEESEMEWLEIQEEIETIEQSVRAEA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLCLLGYYPCQYLLCKPTSMITISQAQLVRGSKTLLDETSLTVYPGHKVGLVGANGSGK
CEEEEEECCCHHEEEECCCCEEEECHHHHHCCCHHHHCCCCEEEECCCEEEEEECCCCCH
SSLLALILGKISLDKGEFTMPSGWQMATVAQETPALDVSAIEYVIDGDSEYRELEAELHA
HHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCHHHEEEEECCCHHHHHHHHHHHH
AQEADDGHKIALLHGKIDAIGGYAIHSRAASLLAGLGFSEQEQSNPVKSFSGGWRMRLNL
HHCCCCCCEEEEEECCEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCCEEEHHH
AQALLCRSDLLLLDEPTNHLDLDTMYWLEGWIKAYQGTLILISHDRDFIDGIVDEIVHVE
HHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHC
NTKLNYYKGNYTSFERVRAERMAQQQVAFERQQKERAHMQSFVDRFRYKASKAKQAQSRL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALERMAELLPSQADSPFHMAFREPEALPNPLVTMEQVSIGYGETEILKKVHLNLVPGAR
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEHHHHHCCCCHHHHHHHHHHEECCCCE
IGLLGRNGAGKSTLVKLLSGELSPMKGQYETNPGLNIGYFAQHQLEFLSLDDSPLQHMVR
EEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHCCEEEEECCCHHHHHHHH
LAPTTKEQELRNFLGGYGFNGDMALSPVRPFSGGEKARLVLALLVWQRPNLLLLDEPTNH
HCCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCC
LDLEMRHALTMALQTFEGAMIIVSHDRHLLRLSCSDYYLVDQGEVKSFDGDLDDYHQWLL
CCHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHH
DAAKTAGKSEETETGKPVQDKKLQKRLDAELRQKLSPLKKVQTKLEKEQHKANERLKELE
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLADTSLYDADNKAKLTQVLTERTTLTQGLEESEMEWLEIQEEIETIEQSVRAEA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]