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The map label for this gene is putA [H]

Identifier: 157963304

GI number: 157963304

Start: 4262331

End: 4265525

Strand: Direct

Name: putA [H]

Synonym: Spea_3490

Alternate gene names: 157963304

Gene position: 4262331-4265525 (Clockwise)

Preceding gene: 157963303

Following gene: 157963305

Centisome position: 82.37

GC content: 46.1

Gene sequence:

>3195_bases
ATGGAAGCGATTATTATGTTCAAAGCGAGTGAAGTTCTAGCTGGTCATTATGATACAGCCGATCTCAACGAACTGTTCCA
AGCGATCAGCGATAATTACATTGTCGATGAAGAACAATATTTATCTGATTTGATAAAGCTAGTTCCTTCAAGTGATGAAG
AGATCAACCGTGTGACCACCCGAGCACACGAGCTAGTTAATAAAGTCCGTCAATACGACAAGAAAGGCCTTATGGTCGGT
GTTGACGCTTTCCTTCAGCAATATAGCTTAGAGACTCAGGAAGGCATTATTTTAATGTGTCTTGCCGAGGCGCTACTGCG
TATTCCTGATGCCGCCACCGCCGACGCACTAATCGAAGACAAGCTATCGGGTGCTAAGTGGGATGAACATTTAAGCAAGA
GTGATTCAATCCTAGTAAATGCATCCACCTGGGGGTTAATGTTAACGGGTAAAATCGTTAAGCTGGATCATAGTATTGAC
GGTAAACCCAGTAGCCTACTCAACCGCCTAGTCAATAAAGTTGGCGAACCAGTCATTAGACAATCCATGCTTGCAGCAAT
GAAGATCATGGGTAAGCAGTTTGTACTAGGTCGTACCGTTAAAGAAGCCCTCAAGAACAGCAACGACAAACGTAAACTTG
GCTACACCCATAGCTACGACATGTTAGGTGAAGCGGCGCTAACGAAAAAAGACGCGCTAAAATACTTCGAAGATTACTCA
AGCGCTATTGCTTCTCTAGGTGCTCAAGAATATGACACTAGCGATGCGCCTCGCCCAACTATCTCTATCAAGCTTTCTGC
ACTGCATCCTCGCTATGAAGTCGCCAATGAAGACAGAATACTCACCGAGCTGTATGACACGCTAATTCTGCTTATCAAGC
AAGCTCGCAGCCTTAATGTGGGGATTTCAATTGACGCAGAAGAGATGGATAGACTTGAACTTTCTCTCAAGCTATTCCAG
CAATTATATAACTCAGATGCAGCAAAAGGCTGGGGACTGTTAGGTATCGTTGTTCAGGCCTATTCAAAGCGCGCCTTACC
TGTACTTTGCTGGTTAACCCGCCTGTCAAAAGATCAAGGCGATGAGATCCCACTGCGCTTAGTGAAAGGAGCCTATTGGG
ACAGTGAACTTAAATGGGCACAAGAGAACGGCGAAGGTGGTTACCCACTTTATACTCGCAAAGCCGGTACCGATGTTTCA
TATCTTGCCTGTGCGCGATACTTGTTATCTGATGCTACTCGCGGCGCGATTTACCCGCAGTTTGCTAGCCATAACGCACA
AACCATTGCCAGTATAACGGACATGGCTGGCGATCGAGAGTATGAATTCCAACGTCTACATGGCATGGGTGAAGAACTCT
ATGACACGCTCTTAGCCGAAAGTGGCGTGAAAAACGTACGTATTTACGCGCCTGTTGGCGCACACAAAGAGCTTTTGCCT
TACCTTGTTCGCCGCCTACTTGAAAATGGTGCCAACACCTCATTTGTACACAAGCTCGTTGATCCTAAGACCCCTATTGA
GTCATTAGTGGGACACCCTTTGACAACACTTATGGGTTACAGAAGCCTGGCTAATAATAAAATCGTTATGCCTGAAGATA
TATTTGGAGCGGAACGTAAAAACTCCAAGGGACTGAACATGAACATCATCTCTGAATCTGCACCATTTTTTGCCGCACTC
GATAAATTTAAAGACACCACTTGGTCAGCGGGTCCGTTAATTAACGGTGAAACCTTAACTGGAGAAACCAAGGAAGTTGT
AAGCCCATTCGATACTAATTTGGTTGTTGGTAAGATAGCCTTCGCCAACAATCAAGCAATAGAGCAAGCACTATCGAGTG
CCGAAGCCGCTTTTCCAAGTTGGTGTAATACACCTGTTGAAGTACGTGCCAATGCCCTACAAAAACTGGCCGACCTGCTT
GAAGAAAACCGTGAAGAGCTTATCGTGCTTTGTACGCGAGAAGCCGGTAAGAGCATACAAGATGGCATCGATGAAGTTCG
TGAAGCTGTAGACTTCTGTCGCTACTATGCTGTGCAAGCGAAGAAGATGATGGCTAAGCCTGAGTTGCTTCCTGGCCCAA
CAGGAGAGCTCAACGAGTTATACTTAGAAGGTCGCGGCATATTTGTTTGTATTAGCCCATGGAACTTCCCATTAGCTATC
TTCTTAGGTCAAGTGACTGCTGCTCTAGCGGTAGGTAATACCGTAATCGCAAAACCAGCAGAGCAGACATCGATTGTTGG
TTACAGAGCGACTCAGCTTGCACATGAAGCAGGTATTCCTAAGGACGTGCTGCAATTCCTACCAGGTACTGGTGCTACAG
TCGGAGCGGCGATTACTTCAGACGAACGTATTGCTGGCGTATGTTTTACTGGTTCTACTGCCACAGCGAAGCTAATTAAC
CGTACACTTGCCATGCGTGAAGGTGCGATTATTCCACTGATTGCGGAAACTGGCGGCCAAAATGCCATGGTGGTCGATTC
AACATCTCAACCAGAGCAAGTGGTTAATGATGTCGTATCTTCTTCTTTCACCAGTGCTGGGCAGCGTTGCTCTGCGTTAC
GAGTGCTGTTTTTACAAGATGACATCGCCGATCGCGTGATCGACGTGATGAAAGGCGCGATGGAAGAACTGACTATTGGT
AATCCAAACTCAGTGAAAACCGATGTTGGCCCAGTAATCGATGCCGCAGCGGCTGCTAACTTAAATGCGCATATTGACCA
TATTAAGCAAGTGGGCAAGCTACTCAAGCAAGTCGAACTGCCTGAAAACACTAAAAATGGTTACTATGTAGCGCCAACAG
CAGTAGAGATTGACTCGATTAAAATGCTGGAAAAAGAGCACTTCGGTCCAATTTTGCATGTTATCCGTTACAAGTCTTCA
GAGCTTGATAAGGTAATCGCCGAGATCAACTCAACCAACTTTGGTCTGACTTTAGGCATTCACAGCCGTAACGAAGGCCA
CGCCCTCAAACTCGCTGATAAGGTGAGAGCGGGTAACGTTTATATCAATCGTAATCAGATTGGTGCAGTAGTTGGGGTTC
AACCTTTCGGTGGCCAAGGCCTATCTGGCACAGGCCCTAAAGCCGGTGGTCCACACTACCTAACGCGCTTTATTACTGAA
AAAACTCACACCAACAATATTACCGCTATTGGTGGTAATGCGACCCTGTTGTCATTAGGTGATAGCGAAGATTAG

Upstream 100 bases:

>100_bases
TTATAATCGGCCCCGCGAACGCCTTGGATTGTATACAAAAGAATAACAACAGAGGTTTTGTCGCAACACCTTACCCAAGC
AATCGGCCCCTACGGCCTAG

Downstream 100 bases:

>100_bases
TGACCACTTAAGTCGCTAAACAGATAAAGGCGTTACGCCACTGTAATAAAGGCCGCTTACGATTGTAAGCGGCCTTTTTA
ATCGCCACCTTTCACGCACT

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1064; Mature: 1064

Protein sequence:

>1064_residues
MEAIIMFKASEVLAGHYDTADLNELFQAISDNYIVDEEQYLSDLIKLVPSSDEEINRVTTRAHELVNKVRQYDKKGLMVG
VDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHLSKSDSILVNASTWGLMLTGKIVKLDHSID
GKPSSLLNRLVNKVGEPVIRQSMLAAMKIMGKQFVLGRTVKEALKNSNDKRKLGYTHSYDMLGEAALTKKDALKYFEDYS
SAIASLGAQEYDTSDAPRPTISIKLSALHPRYEVANEDRILTELYDTLILLIKQARSLNVGISIDAEEMDRLELSLKLFQ
QLYNSDAAKGWGLLGIVVQAYSKRALPVLCWLTRLSKDQGDEIPLRLVKGAYWDSELKWAQENGEGGYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTIASITDMAGDREYEFQRLHGMGEELYDTLLAESGVKNVRIYAPVGAHKELLP
YLVRRLLENGANTSFVHKLVDPKTPIESLVGHPLTTLMGYRSLANNKIVMPEDIFGAERKNSKGLNMNIISESAPFFAAL
DKFKDTTWSAGPLINGETLTGETKEVVSPFDTNLVVGKIAFANNQAIEQALSSAEAAFPSWCNTPVEVRANALQKLADLL
EENREELIVLCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELYLEGRGIFVCISPWNFPLAI
FLGQVTAALAVGNTVIAKPAEQTSIVGYRATQLAHEAGIPKDVLQFLPGTGATVGAAITSDERIAGVCFTGSTATAKLIN
RTLAMREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQDDIADRVIDVMKGAMEELTIG
NPNSVKTDVGPVIDAAAAANLNAHIDHIKQVGKLLKQVELPENTKNGYYVAPTAVEIDSIKMLEKEHFGPILHVIRYKSS
ELDKVIAEINSTNFGLTLGIHSRNEGHALKLADKVRAGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFITE
KTHTNNITAIGGNATLLSLGDSED

Sequences:

>Translated_1064_residues
MEAIIMFKASEVLAGHYDTADLNELFQAISDNYIVDEEQYLSDLIKLVPSSDEEINRVTTRAHELVNKVRQYDKKGLMVG
VDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHLSKSDSILVNASTWGLMLTGKIVKLDHSID
GKPSSLLNRLVNKVGEPVIRQSMLAAMKIMGKQFVLGRTVKEALKNSNDKRKLGYTHSYDMLGEAALTKKDALKYFEDYS
SAIASLGAQEYDTSDAPRPTISIKLSALHPRYEVANEDRILTELYDTLILLIKQARSLNVGISIDAEEMDRLELSLKLFQ
QLYNSDAAKGWGLLGIVVQAYSKRALPVLCWLTRLSKDQGDEIPLRLVKGAYWDSELKWAQENGEGGYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTIASITDMAGDREYEFQRLHGMGEELYDTLLAESGVKNVRIYAPVGAHKELLP
YLVRRLLENGANTSFVHKLVDPKTPIESLVGHPLTTLMGYRSLANNKIVMPEDIFGAERKNSKGLNMNIISESAPFFAAL
DKFKDTTWSAGPLINGETLTGETKEVVSPFDTNLVVGKIAFANNQAIEQALSSAEAAFPSWCNTPVEVRANALQKLADLL
EENREELIVLCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELYLEGRGIFVCISPWNFPLAI
FLGQVTAALAVGNTVIAKPAEQTSIVGYRATQLAHEAGIPKDVLQFLPGTGATVGAAITSDERIAGVCFTGSTATAKLIN
RTLAMREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQDDIADRVIDVMKGAMEELTIG
NPNSVKTDVGPVIDAAAAANLNAHIDHIKQVGKLLKQVELPENTKNGYYVAPTAVEIDSIKMLEKEHFGPILHVIRYKSS
ELDKVIAEINSTNFGLTLGIHSRNEGHALKLADKVRAGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFITE
KTHTNNITAIGGNATLLSLGDSED
>Mature_1064_residues
MEAIIMFKASEVLAGHYDTADLNELFQAISDNYIVDEEQYLSDLIKLVPSSDEEINRVTTRAHELVNKVRQYDKKGLMVG
VDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIEDKLSGAKWDEHLSKSDSILVNASTWGLMLTGKIVKLDHSID
GKPSSLLNRLVNKVGEPVIRQSMLAAMKIMGKQFVLGRTVKEALKNSNDKRKLGYTHSYDMLGEAALTKKDALKYFEDYS
SAIASLGAQEYDTSDAPRPTISIKLSALHPRYEVANEDRILTELYDTLILLIKQARSLNVGISIDAEEMDRLELSLKLFQ
QLYNSDAAKGWGLLGIVVQAYSKRALPVLCWLTRLSKDQGDEIPLRLVKGAYWDSELKWAQENGEGGYPLYTRKAGTDVS
YLACARYLLSDATRGAIYPQFASHNAQTIASITDMAGDREYEFQRLHGMGEELYDTLLAESGVKNVRIYAPVGAHKELLP
YLVRRLLENGANTSFVHKLVDPKTPIESLVGHPLTTLMGYRSLANNKIVMPEDIFGAERKNSKGLNMNIISESAPFFAAL
DKFKDTTWSAGPLINGETLTGETKEVVSPFDTNLVVGKIAFANNQAIEQALSSAEAAFPSWCNTPVEVRANALQKLADLL
EENREELIVLCTREAGKSIQDGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELYLEGRGIFVCISPWNFPLAI
FLGQVTAALAVGNTVIAKPAEQTSIVGYRATQLAHEAGIPKDVLQFLPGTGATVGAAITSDERIAGVCFTGSTATAKLIN
RTLAMREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVSSSFTSAGQRCSALRVLFLQDDIADRVIDVMKGAMEELTIG
NPNSVKTDVGPVIDAAAAANLNAHIDHIKQVGKLLKQVELPENTKNGYYVAPTAVEIDSIKMLEKEHFGPILHVIRYKSS
ELDKVIAEINSTNFGLTLGIHSRNEGHALKLADKVRAGNVYINRNQIGAVVGVQPFGGQGLSGTGPKAGGPHYLTRFITE
KTHTNNITAIGGNATLLSLGDSED

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=489, Percent_Identity=30.2658486707566, Blast_Score=209, Evalue=9e-54,
Organism=Homo sapiens, GI25777734, Length=489, Percent_Identity=30.2658486707566, Blast_Score=209, Evalue=9e-54,
Organism=Homo sapiens, GI238859541, Length=489, Percent_Identity=30.2658486707566, Blast_Score=209, Evalue=1e-53,
Organism=Homo sapiens, GI153266822, Length=446, Percent_Identity=31.1659192825112, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI21614513, Length=487, Percent_Identity=30.3901437371663, Blast_Score=191, Evalue=4e-48,
Organism=Homo sapiens, GI21361176, Length=480, Percent_Identity=30.2083333333333, Blast_Score=187, Evalue=7e-47,
Organism=Homo sapiens, GI25777732, Length=468, Percent_Identity=30.1282051282051, Blast_Score=186, Evalue=9e-47,
Organism=Homo sapiens, GI238814322, Length=487, Percent_Identity=28.7474332648871, Blast_Score=183, Evalue=9e-46,
Organism=Homo sapiens, GI25777724, Length=477, Percent_Identity=29.1404612159329, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI12007648, Length=460, Percent_Identity=28.0434782608696, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI25777730, Length=467, Percent_Identity=29.1220556745182, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI25777728, Length=416, Percent_Identity=30.0480769230769, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI115387104, Length=445, Percent_Identity=26.7415730337079, Blast_Score=157, Evalue=5e-38,
Organism=Homo sapiens, GI188035924, Length=482, Percent_Identity=27.3858921161826, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI310128093, Length=463, Percent_Identity=27.8617710583153, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI310128103, Length=463, Percent_Identity=27.8617710583153, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI25952152, Length=453, Percent_Identity=27.5938189845475, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI4507229, Length=431, Percent_Identity=28.3062645011601, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI11095441, Length=420, Percent_Identity=27.3809523809524, Blast_Score=136, Evalue=9e-32,
Organism=Homo sapiens, GI25777721, Length=444, Percent_Identity=27.2522522522523, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI310128091, Length=422, Percent_Identity=28.1990521327014, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI25777726, Length=477, Percent_Identity=25.1572327044025, Blast_Score=127, Evalue=7e-29,
Organism=Homo sapiens, GI206597441, Length=447, Percent_Identity=25.0559284116331, Blast_Score=113, Evalue=8e-25,
Organism=Homo sapiens, GI206597439, Length=447, Percent_Identity=25.0559284116331, Blast_Score=113, Evalue=8e-25,
Organism=Homo sapiens, GI22907049, Length=447, Percent_Identity=25.0559284116331, Blast_Score=113, Evalue=8e-25,
Organism=Homo sapiens, GI4502043, Length=423, Percent_Identity=25.7683215130024, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI238814371, Length=423, Percent_Identity=25.7683215130024, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI310128087, Length=284, Percent_Identity=27.4647887323944, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI71773324, Length=419, Percent_Identity=24.582338902148, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=29.0519877675841, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI4557303, Length=437, Percent_Identity=23.3409610983982, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI73466520, Length=437, Percent_Identity=23.3409610983982, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI301500698, Length=280, Percent_Identity=26.7857142857143, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=27.7955271565495, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI73695881, Length=330, Percent_Identity=25.1515151515152, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI73695879, Length=330, Percent_Identity=25.1515151515152, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI310128097, Length=260, Percent_Identity=29.2307692307692, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI310128099, Length=234, Percent_Identity=27.3504273504274, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI310128101, Length=232, Percent_Identity=27.1551724137931, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI223972651, Length=444, Percent_Identity=24.3243243243243, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1787250, Length=1042, Percent_Identity=47.0249520153551, Blast_Score=896, Evalue=0.0,
Organism=Escherichia coli, GI87081896, Length=484, Percent_Identity=32.2314049586777, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1787558, Length=479, Percent_Identity=31.3152400835073, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI1787715, Length=462, Percent_Identity=32.034632034632, Blast_Score=187, Evalue=4e-48,
Organism=Escherichia coli, GI1789015, Length=473, Percent_Identity=29.3868921775898, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1788042, Length=459, Percent_Identity=30.5010893246187, Blast_Score=176, Evalue=1e-44,
Organism=Escherichia coli, GI1787684, Length=463, Percent_Identity=29.1576673866091, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1786504, Length=458, Percent_Identity=27.0742358078603, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI87082295, Length=468, Percent_Identity=27.991452991453, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI87081926, Length=415, Percent_Identity=27.9518072289157, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1787653, Length=344, Percent_Identity=21.5116279069767, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17534447, Length=474, Percent_Identity=32.4894514767932, Blast_Score=208, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI115532534, Length=395, Percent_Identity=33.1645569620253, Blast_Score=187, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17562198, Length=468, Percent_Identity=31.4102564102564, Blast_Score=186, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI133930964, Length=473, Percent_Identity=28.5412262156448, Blast_Score=177, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI25144435, Length=468, Percent_Identity=29.4871794871795, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17551164, Length=463, Percent_Identity=29.1576673866091, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=485, Percent_Identity=29.0721649484536, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564736, Length=404, Percent_Identity=30.4455445544554, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564151, Length=422, Percent_Identity=30.5687203791469, Blast_Score=160, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71995606, Length=464, Percent_Identity=26.9396551724138, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17534119, Length=481, Percent_Identity=25.987525987526, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71995613, Length=420, Percent_Identity=25.7142857142857, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI25143874, Length=435, Percent_Identity=25.7471264367816, Blast_Score=136, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI25143876, Length=435, Percent_Identity=25.7471264367816, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=434, Percent_Identity=27.4193548387097, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71990744, Length=306, Percent_Identity=30.0653594771242, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25146391, Length=453, Percent_Identity=24.7240618101545, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25146394, Length=453, Percent_Identity=24.7240618101545, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32566756, Length=453, Percent_Identity=24.7240618101545, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17564084, Length=460, Percent_Identity=24.1304347826087, Blast_Score=103, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320917, Length=469, Percent_Identity=31.3432835820896, Blast_Score=196, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324950, Length=463, Percent_Identity=29.8056155507559, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323822, Length=488, Percent_Identity=29.5081967213115, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321826, Length=517, Percent_Identity=29.0135396518375, Blast_Score=184, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6323821, Length=473, Percent_Identity=30.2325581395349, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6325196, Length=460, Percent_Identity=30.4347826086957, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6319478, Length=487, Percent_Identity=26.2833675564682, Blast_Score=151, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321828, Length=454, Percent_Identity=24.8898678414097, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323757, Length=416, Percent_Identity=22.8365384615385, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668425, Length=485, Percent_Identity=29.4845360824742, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24668417, Length=485, Percent_Identity=29.4845360824742, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24668413, Length=485, Percent_Identity=29.4845360824742, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24585660, Length=489, Percent_Identity=29.4478527607362, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI20129399, Length=483, Percent_Identity=30.8488612836439, Blast_Score=186, Evalue=7e-47,
Organism=Drosophila melanogaster, GI281362580, Length=464, Percent_Identity=28.448275862069, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472918, Length=464, Percent_Identity=28.448275862069, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472926, Length=464, Percent_Identity=28.448275862069, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI62472936, Length=464, Percent_Identity=28.448275862069, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356737, Length=464, Percent_Identity=28.448275862069, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24650465, Length=481, Percent_Identity=29.5218295218295, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28571798, Length=497, Percent_Identity=26.7605633802817, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571796, Length=497, Percent_Identity=26.7605633802817, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571794, Length=497, Percent_Identity=26.7605633802817, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571806, Length=497, Percent_Identity=26.7605633802817, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571802, Length=497, Percent_Identity=26.7605633802817, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28571800, Length=497, Percent_Identity=26.7605633802817, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24666674, Length=484, Percent_Identity=27.6859504132231, Blast_Score=153, Evalue=5e-37,
Organism=Drosophila melanogaster, GI28574525, Length=484, Percent_Identity=25.4132231404959, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24638878, Length=447, Percent_Identity=28.1879194630872, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24638876, Length=447, Percent_Identity=28.1879194630872, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281360299, Length=440, Percent_Identity=25.2272727272727, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360297, Length=440, Percent_Identity=25.2272727272727, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360295, Length=440, Percent_Identity=25.2272727272727, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24586250, Length=440, Percent_Identity=25.2272727272727, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360301, Length=436, Percent_Identity=25.2293577981651, Blast_Score=87, Evalue=8e-17,
Organism=Drosophila melanogaster, GI45552499, Length=440, Percent_Identity=25, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281360303, Length=436, Percent_Identity=25, Blast_Score=86, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 116099; Mature: 116099

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIIMFKASEVLAGHYDTADLNELFQAISDNYIVDEEQYLSDLIKLVPSSDEEINRVTT
CCEEEEEECHHHHHCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCHHHHHHHH
RAHELVNKVRQYDKKGLMVGVDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIED
HHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KLSGAKWDEHLSKSDSILVNASTWGLMLTGKIVKLDHSIDGKPSSLLNRLVNKVGEPVIR
HCCCCCHHHHCCCCCCEEEEECCCCEEEECEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
QSMLAAMKIMGKQFVLGRTVKEALKNSNDKRKLGYTHSYDMLGEAALTKKDALKYFEDYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAIASLGAQEYDTSDAPRPTISIKLSALHPRYEVANEDRILTELYDTLILLIKQARSLNV
HHHHHCCCCCCCCCCCCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
GISIDAEEMDRLELSLKLFQQLYNSDAAKGWGLLGIVVQAYSKRALPVLCWLTRLSKDQG
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
DEIPLRLVKGAYWDSELKWAQENGEGGYPLYTRKAGTDVSYLACARYLLSDATRGAIYPQ
CCCCHHHHHCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCH
FASHNAQTIASITDMAGDREYEFQRLHGMGEELYDTLLAESGVKNVRIYAPVGAHKELLP
HHCCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
YLVRRLLENGANTSFVHKLVDPKTPIESLVGHPLTTLMGYRSLANNKIVMPEDIFGAERK
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCCCEECCHHHCCCCCC
NSKGLNMNIISESAPFFAALDKFKDTTWSAGPLINGETLTGETKEVVSPFDTNLVVGKIA
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEE
FANNQAIEQALSSAEAAFPSWCNTPVEVRANALQKLADLLEENREELIVLCTREAGKSIQ
ECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHCCHHH
DGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELYLEGRGIFVCISPWNFPLAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEECCEEEEEECCCCCHHHH
FLGQVTAALAVGNTVIAKPAEQTSIVGYRATQLAHEAGIPKDVLQFLPGTGATVGAAITS
HHHHHHHHHHHCCEEEECCCCHHHEEHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEECC
DERIAGVCFTGSTATAKLINRTLAMREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVS
CCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHH
SSFTSAGQRCSALRVLFLQDDIADRVIDVMKGAMEELTIGNPNSVKTDVGPVIDAAAAAN
HHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC
LNAHIDHIKQVGKLLKQVELPENTKNGYYVAPTAVEIDSIKMLEKEHFGPILHVIRYKSS
CHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEHHHHHHHHHHHCCHHHHHHHCCCH
ELDKVIAEINSTNFGLTLGIHSRNEGHALKLADKVRAGNVYINRNQIGAVVGVQPFGGQG
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHEECCEEEECCCCCEEEEECCCCCCC
LSGTGPKAGGPHYLTRFITEKTHTNNITAIGGNATLLSLGDSED
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCEEEEECCCCCC
>Mature Secondary Structure
MEAIIMFKASEVLAGHYDTADLNELFQAISDNYIVDEEQYLSDLIKLVPSSDEEINRVTT
CCEEEEEECHHHHHCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCCCCCHHHHHHHH
RAHELVNKVRQYDKKGLMVGVDAFLQQYSLETQEGIILMCLAEALLRIPDAATADALIED
HHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
KLSGAKWDEHLSKSDSILVNASTWGLMLTGKIVKLDHSIDGKPSSLLNRLVNKVGEPVIR
HCCCCCHHHHCCCCCCEEEEECCCCEEEECEEEEECCCCCCCHHHHHHHHHHHHCCHHHH
QSMLAAMKIMGKQFVLGRTVKEALKNSNDKRKLGYTHSYDMLGEAALTKKDALKYFEDYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAIASLGAQEYDTSDAPRPTISIKLSALHPRYEVANEDRILTELYDTLILLIKQARSLNV
HHHHHCCCCCCCCCCCCCCEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
GISIDAEEMDRLELSLKLFQQLYNSDAAKGWGLLGIVVQAYSKRALPVLCWLTRLSKDQG
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
DEIPLRLVKGAYWDSELKWAQENGEGGYPLYTRKAGTDVSYLACARYLLSDATRGAIYPQ
CCCCHHHHHCCCCCCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCH
FASHNAQTIASITDMAGDREYEFQRLHGMGEELYDTLLAESGVKNVRIYAPVGAHKELLP
HHCCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
YLVRRLLENGANTSFVHKLVDPKTPIESLVGHPLTTLMGYRSLANNKIVMPEDIFGAERK
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCCCEECCHHHCCCCCC
NSKGLNMNIISESAPFFAALDKFKDTTWSAGPLINGETLTGETKEVVSPFDTNLVVGKIA
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEE
FANNQAIEQALSSAEAAFPSWCNTPVEVRANALQKLADLLEENREELIVLCTREAGKSIQ
ECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHCCHHH
DGIDEVREAVDFCRYYAVQAKKMMAKPELLPGPTGELNELYLEGRGIFVCISPWNFPLAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEECCEEEEEECCCCCHHHH
FLGQVTAALAVGNTVIAKPAEQTSIVGYRATQLAHEAGIPKDVLQFLPGTGATVGAAITS
HHHHHHHHHHHCCEEEECCCCHHHEEHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEECC
DERIAGVCFTGSTATAKLINRTLAMREGAIIPLIAETGGQNAMVVDSTSQPEQVVNDVVS
CCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHH
SSFTSAGQRCSALRVLFLQDDIADRVIDVMKGAMEELTIGNPNSVKTDVGPVIDAAAAAN
HHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC
LNAHIDHIKQVGKLLKQVELPENTKNGYYVAPTAVEIDSIKMLEKEHFGPILHVIRYKSS
CHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEHHHHHHHHHHHCCHHHHHHHCCCH
ELDKVIAEINSTNFGLTLGIHSRNEGHALKLADKVRAGNVYINRNQIGAVVGVQPFGGQG
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHEECCEEEECCCCCEEEEECCCCCCC
LSGTGPKAGGPHYLTRFITEKTHTNNITAIGGNATLLSLGDSED
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]